Motif ID: Gata6

Z-value: 0.342


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 1.634 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_-_103853199 1.510 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr4_+_13751297 0.948 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_45628176 0.701 ENSMUST00000130850.1
 Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627946 0.596 ENSMUST00000145458.1
 Sorbs2
sorbin and SH3 domain containing 2
chr2_+_65930117 0.535 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr8_+_45627709 0.508 ENSMUST00000134321.1
ENSMUST00000135336.1
 Sorbs2

sorbin and SH3 domain containing 2

chr12_+_95692212 0.442 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr11_+_67586675 0.354 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr1_+_179803376 0.334 ENSMUST00000097454.2
 Gm10518
predicted gene 10518
chr16_-_34262945 0.269 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr2_-_172370506 0.257 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
 Aurka


aurora kinase A


chr5_-_73191848 0.237 ENSMUST00000176910.1
 Fryl
furry homolog-like (Drosophila)
chr1_-_25829511 0.233 ENSMUST00000135518.1
ENSMUST00000151309.1
 Bai3

brain-specific angiogenesis inhibitor 3

chr8_-_122699066 0.230 ENSMUST00000127984.1
 Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr2_+_80617045 0.228 ENSMUST00000028384.4
 Dusp19
dual specificity phosphatase 19
chr6_+_86078070 0.227 ENSMUST00000032069.5
 Add2
adducin 2 (beta)
chr2_+_125859134 0.195 ENSMUST00000028636.6
ENSMUST00000125084.1
 Galk2

galactokinase 2

chr3_-_154330543 0.188 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr17_+_34604819 0.174 ENSMUST00000173242.1
 Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr9_+_66350465 0.156 ENSMUST00000042824.6
 Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr9_+_44379490 0.154 ENSMUST00000066601.6
 Hyou1
hypoxia up-regulated 1
chr9_+_62342449 0.152 ENSMUST00000156461.1
 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr11_+_4883186 0.149 ENSMUST00000139737.1
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr10_+_40883469 0.147 ENSMUST00000019975.7
 Wasf1
WAS protein family, member 1
chr19_+_4711153 0.142 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr10_-_34207551 0.140 ENSMUST00000048010.7
 Dse
dermatan sulfate epimerase
chr5_-_30461902 0.139 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
 Otof



otoferlin



chr3_-_92429403 0.136 ENSMUST00000047300.7
 Gm9774
predicted pseudogene 9774
chr17_+_71204647 0.135 ENSMUST00000126681.1
 Lpin2
lipin 2
chr6_-_127109517 0.134 ENSMUST00000039913.8
 9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr5_+_121777929 0.134 ENSMUST00000160821.1
 Atxn2
ataxin 2
chr1_+_152954966 0.133 ENSMUST00000043313.8
 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr15_-_103251465 0.125 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
 Nfe2




nuclear factor, erythroid derived 2




chr9_-_29963112 0.123 ENSMUST00000075069.4
 Ntm
neurotrimin
chr4_-_110287479 0.113 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
 Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr16_-_46010212 0.112 ENSMUST00000130481.1
 Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr2_-_7395879 0.112 ENSMUST00000182404.1
 Celf2
CUGBP, Elav-like family member 2
chr6_-_38124568 0.111 ENSMUST00000040259.4
 Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr11_-_102365111 0.106 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr2_-_7396192 0.105 ENSMUST00000137733.2
 Celf2
CUGBP, Elav-like family member 2
chr6_-_7983424 0.096 ENSMUST00000178598.1
 Gm9825
predicted gene 9825
chr2_+_71786923 0.094 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr6_-_136875794 0.090 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr2_-_7081207 0.087 ENSMUST00000114923.2
ENSMUST00000182706.1
 Celf2

CUGBP, Elav-like family member 2

chr9_-_95815389 0.085 ENSMUST00000119760.1
 Pls1
plastin 1 (I-isoform)
chr6_+_58831748 0.080 ENSMUST00000126292.1
ENSMUST00000031823.5
 Herc3

hect domain and RLD 3

chr2_+_110597298 0.078 ENSMUST00000045972.6
ENSMUST00000111026.2
 Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr18_-_43477764 0.078 ENSMUST00000057110.9
 Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr2_+_143915273 0.076 ENSMUST00000103172.3
 Dstn
destrin
chr10_+_53337686 0.074 ENSMUST00000046221.6
ENSMUST00000163319.1
 Pln

phospholamban

chr11_+_95712673 0.067 ENSMUST00000107717.1
 Zfp652
zinc finger protein 652
chr9_-_106887000 0.065 ENSMUST00000055843.7
 Rbm15b
RNA binding motif protein 15B
chr2_-_7081256 0.057 ENSMUST00000183209.1
 Celf2
CUGBP, Elav-like family member 2
chr15_-_83170168 0.055 ENSMUST00000162834.1
 Cyb5r3
cytochrome b5 reductase 3
chr2_+_68104671 0.048 ENSMUST00000042456.3
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_-_59948155 0.045 ENSMUST00000153136.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr7_-_99238564 0.037 ENSMUST00000064231.7
 Mogat2
monoacylglycerol O-acyltransferase 2
chr7_-_119895446 0.034 ENSMUST00000098080.2
 Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr17_-_33713372 0.032 ENSMUST00000173392.1
 March2
membrane-associated ring finger (C3HC4) 2
chr16_+_58670208 0.031 ENSMUST00000060077.5
 Cpox
coproporphyrinogen oxidase
chr15_-_83170498 0.031 ENSMUST00000162178.1
 Cyb5r3
cytochrome b5 reductase 3
chr10_+_52417532 0.028 ENSMUST00000023830.8
 Nus1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr10_-_86732409 0.028 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr6_+_58833689 0.028 ENSMUST00000041401.8
 Herc3
hect domain and RLD 3
chr13_+_24802020 0.026 ENSMUST00000155575.1
 BC005537
cDNA sequence BC005537
chr9_-_44342332 0.025 ENSMUST00000097558.3
 Hmbs
hydroxymethylbilane synthase
chr10_-_40883073 0.017 ENSMUST00000044166.7
 Cdc40
cell division cycle 40
chr11_+_98026695 0.011 ENSMUST00000092425.4
 Rpl19
ribosomal protein L19
chr2_-_125859139 0.009 ENSMUST00000110463.1
ENSMUST00000028635.5
 Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

chr11_+_4986824 0.006 ENSMUST00000009234.9
ENSMUST00000109897.1
 Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr2_-_7395968 0.001 ENSMUST00000002176.6
 Celf2
CUGBP, Elav-like family member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0015671 oxygen transport(GO:0015671)
0.3 1.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.3 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.1 1.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.3 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 0.2 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)