Motif ID: Mybl2

Z-value: 1.407


Transcription factors associated with Mybl2:

Gene SymbolEntrez IDGene Name
Mybl2 ENSMUSG00000017861.5 Mybl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl2mm10_v2_chr2_+_163054682_1630546930.491.7e-02Click!


Activity profile for motif Mybl2.

activity profile for motif Mybl2


Sorted Z-values histogram for motif Mybl2

Sorted Z-values for motif Mybl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mybl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_79977782 4.449 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chr2_+_13573927 4.431 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr15_+_26309039 3.401 ENSMUST00000140840.1
ENSMUST00000152841.1
March11

membrane-associated ring finger (C3HC4) 11

chr11_-_106999369 3.349 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr1_-_169531343 3.028 ENSMUST00000028000.7
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr8_-_80739497 2.679 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr19_-_41802028 2.648 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr11_-_106999482 2.638 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr1_-_169531447 2.594 ENSMUST00000111368.1
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_125404292 2.413 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr4_-_107684228 2.404 ENSMUST00000069271.4
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr14_-_67715585 2.334 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr1_+_57995971 2.332 ENSMUST00000027202.8
Sgol2
shugoshin-like 2 (S. pombe)
chr4_-_41695935 2.273 ENSMUST00000145379.1
Cntfr
ciliary neurotrophic factor receptor
chr4_-_115133977 2.226 ENSMUST00000051400.7
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr4_-_116627921 2.153 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr13_+_51645232 2.048 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr2_-_181043540 2.016 ENSMUST00000124400.1
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
chr11_-_90002881 1.966 ENSMUST00000020864.8
Pctp
phosphatidylcholine transfer protein
chr19_+_5366764 1.965 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 137 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 5.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 4.7 GO:0043486 histone exchange(GO:0043486)
0.9 4.4 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 3.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.4 3.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 2.7 GO:0016584 nucleosome positioning(GO:0016584)
0.2 2.7 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 2.7 GO:0007099 centriole replication(GO:0007099)
0.1 2.6 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.0 2.6 GO:0006413 translational initiation(GO:0006413)
0.6 2.3 GO:0003360 brainstem development(GO:0003360)
0.3 2.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 2.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 2.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 2.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.7 2.0 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.0 2.0 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.8 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 1.8 GO:0060009 Sertoli cell development(GO:0060009)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.1 GO:0005643 nuclear pore(GO:0005643)
1.0 6.2 GO:0031262 Ndc80 complex(GO:0031262)
1.1 4.4 GO:0045098 type III intermediate filament(GO:0045098)
0.0 2.8 GO:0000922 spindle pole(GO:0000922)
0.2 2.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 2.7 GO:0005871 kinesin complex(GO:0005871)
0.0 2.7 GO:0000786 nucleosome(GO:0000786)
0.8 2.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.2 2.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 1.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 1.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 1.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 1.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923)
0.3 1.3 GO:0097413 Lewy body(GO:0097413)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.2 GO:0044530 supraspliceosomal complex(GO:0044530)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 106 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 5.5 GO:0003743 translation initiation factor activity(GO:0003743)
1.1 4.4 GO:1990254 keratin filament binding(GO:1990254)
0.5 3.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 3.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 2.5 GO:0031491 nucleosome binding(GO:0031491)
0.3 2.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.4 2.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 2.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 2.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 2.0 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 1.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.6 1.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.7 GO:0048487 beta-tubulin binding(GO:0048487)