Motif ID: Stat5a

Z-value: 0.983


Transcription factors associated with Stat5a:

Gene SymbolEntrez IDGene Name
Stat5a ENSMUSG00000004043.8 Stat5a



Activity profile for motif Stat5a.

activity profile for motif Stat5a


Sorted Z-values histogram for motif Stat5a

Sorted Z-values for motif Stat5a



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat5a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_22689771 5.049 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr18_+_20665250 1.900 ENSMUST00000075312.3
 Ttr
transthyretin
chr11_-_55419898 1.402 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr16_-_23890805 1.346 ENSMUST00000004480.3
 Sst
somatostatin
chr8_-_71537402 1.300 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2
chrY_-_1245753 1.299 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr8_+_94179089 1.267 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr5_-_77408034 1.233 ENSMUST00000163898.1
ENSMUST00000046746.6
 Igfbp7

insulin-like growth factor binding protein 7

chr5_+_104435112 1.193 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr1_-_125913101 1.175 ENSMUST00000161361.1
 Lypd1
Ly6/Plaur domain containing 1
chr11_-_100970887 1.109 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr11_+_78499087 1.072 ENSMUST00000017488.4
 Vtn
vitronectin
chr1_+_90203980 1.069 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr9_-_39604124 1.034 ENSMUST00000042485.4
ENSMUST00000141370.1
 AW551984

expressed sequence AW551984

chr4_+_15881255 0.969 ENSMUST00000029876.1
 Calb1
calbindin 1
chrY_-_1245685 0.967 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
 Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr9_-_77347816 0.958 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr4_-_136898803 0.950 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr7_-_103853199 0.935 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr1_-_75278345 0.913 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 335 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 1.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2 1.6 GO:0097421 liver regeneration(GO:0097421)
0.3 1.3 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.2 1.3 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 1.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 1.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 1.2 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.2 1.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 1.1 GO:0033280 response to vitamin D(GO:0033280)
0.3 1.0 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 1.0 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 1.0 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.0 1.0 GO:0007614 short-term memory(GO:0007614)
0.0 1.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 1.0 GO:0071300 cellular response to retinoic acid(GO:0071300)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 141 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.6 GO:0031225 anchored component of membrane(GO:0031225)
0.5 2.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 2.3 GO:0005581 collagen trimer(GO:0005581)
0.0 2.1 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 1.5 GO:0070469 respiratory chain(GO:0070469)
0.4 1.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.0 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.0 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.2 0.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.2 0.7 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.1 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 218 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 2.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 2.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 1.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.5 1.5 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.2 1.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.1 GO:0005496 steroid binding(GO:0005496)
0.0 1.1 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.3 1.0 GO:0030172 troponin C binding(GO:0030172)
0.2 0.9 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)