Motif ID: Jun

Z-value: 0.447


Transcription factors associated with Jun:

Gene SymbolEntrez IDGene Name
Jun ENSMUSG00000052684.3 Jun

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Junmm10_v2_chr4_-_95052170_95052181-0.184.2e-01Click!


Activity profile for motif Jun.

activity profile for motif Jun


Sorted Z-values histogram for motif Jun

Sorted Z-values for motif Jun



Network of associatons between targets according to the STRING database.



First level regulatory network of Jun

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_139834148 1.753 ENSMUST00000026548.7
 Gpr123
G protein-coupled receptor 123
chr3_+_109573907 1.082 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chrX_+_52791179 0.966 ENSMUST00000101588.1
 Ccdc160
coiled-coil domain containing 160
chr3_-_88503187 0.716 ENSMUST00000120377.1
 Lmna
lamin A
chr2_-_77703252 0.693 ENSMUST00000171063.1
 Zfp385b
zinc finger protein 385B
chr10_+_128933782 0.690 ENSMUST00000099112.2
 Itga7
integrin alpha 7
chrX_-_23266751 0.678 ENSMUST00000115316.2
 Klhl13
kelch-like 13
chr6_+_7555053 0.661 ENSMUST00000090679.2
ENSMUST00000184986.1
 Tac1

tachykinin 1

chr3_-_88503331 0.651 ENSMUST00000029699.6
 Lmna
lamin A
chr10_-_5922385 0.639 ENSMUST00000131996.1
ENSMUST00000064225.7
 Rgs17

regulator of G-protein signaling 17

chr6_+_17463927 0.626 ENSMUST00000115442.1
 Met
met proto-oncogene
chr6_+_17281185 0.615 ENSMUST00000000058.6
 Cav2
caveolin 2
chr3_-_85722474 0.600 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr2_+_25395866 0.558 ENSMUST00000028328.2
 Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr16_-_26989974 0.545 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr6_+_17281304 0.535 ENSMUST00000115459.1
ENSMUST00000115462.1
 Cav2

caveolin 2

chr7_-_142899985 0.535 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr7_-_142372210 0.531 ENSMUST00000084412.5
 Ifitm10
interferon induced transmembrane protein 10
chr6_+_4755327 0.531 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr15_-_97767798 0.514 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
 Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.1 1.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 1.2 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 1.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.2 0.9 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.0 0.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 0.7 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.0 0.7 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.6 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.6 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.2 0.5 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.1 0.5 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.5 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.4 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0051036 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.2 1.4 GO:0005638 lamin filament(GO:0005638)
0.1 1.2 GO:0002080 acrosomal membrane(GO:0002080)
0.2 0.9 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.2 0.7 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0005604 basement membrane(GO:0005604)
0.2 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 1.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 1.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.6 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.2 0.5 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 0.5 GO:0035240 dopamine binding(GO:0035240) catecholamine binding(GO:1901338)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.4 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.4 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)