Motif ID: Maf_Nrl
Z-value: 0.698
Transcription factors associated with Maf_Nrl:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Maf | ENSMUSG00000055435.6 | Maf |
Nrl | ENSMUSG00000040632.9 | Nrl |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Maf | mm10_v2_chr8_-_115707778_115707794 | -0.54 | 8.2e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.6 | GO:0015671 | oxygen transport(GO:0015671) |
0.7 | 2.0 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
0.4 | 2.2 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
0.4 | 2.1 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.3 | 0.9 | GO:2000670 | positive regulation of dendritic cell apoptotic process(GO:2000670) |
0.2 | 1.5 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.2 | 0.7 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.2 | 0.7 | GO:1901731 | calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731) |
0.2 | 0.8 | GO:0046958 | nonassociative learning(GO:0046958) |
0.2 | 0.6 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
0.2 | 0.7 | GO:1904192 | cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193) |
0.2 | 0.4 | GO:0032513 | negative regulation of protein phosphatase type 2B activity(GO:0032513) |
0.2 | 1.9 | GO:0060539 | diaphragm development(GO:0060539) |
0.2 | 1.0 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.2 | 0.6 | GO:0060032 | notochord regression(GO:0060032) |
0.2 | 2.2 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
0.1 | 1.2 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
0.1 | 5.1 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
0.1 | 0.4 | GO:0021557 | oculomotor nerve development(GO:0021557) |
0.1 | 0.4 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
0.1 | 0.4 | GO:0007210 | serotonin receptor signaling pathway(GO:0007210) |
0.1 | 0.4 | GO:0015960 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
0.1 | 0.4 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.1 | 0.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.1 | 0.5 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
0.1 | 0.3 | GO:0021649 | vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) |
0.1 | 1.9 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.1 | 0.7 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.1 | 0.3 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
0.1 | 0.3 | GO:0040009 | regulation of growth rate(GO:0040009) protein poly-ADP-ribosylation(GO:0070212) |
0.1 | 0.3 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
0.1 | 0.2 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.1 | 0.5 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
0.1 | 0.3 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.1 | 0.4 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
0.1 | 0.2 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
0.1 | 0.3 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.1 | 0.3 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) |
0.1 | 0.2 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.1 | 0.3 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
0.1 | 0.5 | GO:1903423 | positive regulation of synaptic vesicle recycling(GO:1903423) |
0.1 | 0.7 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.1 | 0.5 | GO:0061436 | establishment of skin barrier(GO:0061436) |
0.1 | 0.3 | GO:0021764 | amygdala development(GO:0021764) |
0.1 | 0.1 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.1 | 1.2 | GO:0042517 | positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517) |
0.1 | 0.4 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
0.1 | 0.3 | GO:1901524 | regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525) |
0.1 | 0.5 | GO:0060068 | vagina development(GO:0060068) |
0.1 | 0.2 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474) |
0.1 | 0.3 | GO:0007603 | phototransduction, visible light(GO:0007603) |
0.0 | 0.5 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.0 | 0.4 | GO:0040016 | embryonic cleavage(GO:0040016) |
0.0 | 0.4 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.2 | GO:0001927 | exocyst assembly(GO:0001927) |
0.0 | 0.1 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.0 | 0.2 | GO:2001270 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) |
0.0 | 0.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.0 | 0.8 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.0 | 0.8 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.4 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.0 | 0.1 | GO:0048818 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
0.0 | 0.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.3 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
0.0 | 0.7 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.3 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 0.2 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.0 | 0.4 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.0 | 0.1 | GO:0015920 | regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920) |
0.0 | 0.4 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
0.0 | 1.3 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 0.1 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
0.0 | 0.2 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
0.0 | 1.3 | GO:0045806 | negative regulation of endocytosis(GO:0045806) |
0.0 | 0.2 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
0.0 | 1.1 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
0.0 | 0.3 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.0 | 0.2 | GO:0002115 | store-operated calcium entry(GO:0002115) |
0.0 | 0.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.2 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
0.0 | 0.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) phosphate ion transmembrane transport(GO:0035435) |
0.0 | 1.3 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.0 | 0.1 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.0 | 0.7 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
0.0 | 0.2 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.2 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.0 | 0.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.0 | 0.1 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.0 | 0.3 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
0.0 | 0.1 | GO:0090383 | phagosome acidification(GO:0090383) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.6 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.2 | 0.7 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.2 | 0.7 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
0.2 | 0.7 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.1 | 1.3 | GO:0030008 | TRAPP complex(GO:0030008) |
0.1 | 0.4 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
0.1 | 0.3 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.1 | 0.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 0.7 | GO:0005916 | fascia adherens(GO:0005916) |
0.1 | 0.7 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.1 | 5.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.6 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 1.1 | GO:0071565 | nBAF complex(GO:0071565) |
0.0 | 0.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
0.0 | 0.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.2 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.5 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 1.9 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.3 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.0 | 0.4 | GO:0070852 | cell body fiber(GO:0070852) |
0.0 | 0.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 1.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.0 | 0.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 0.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.1 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.0 | 0.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 2.0 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.2 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 2.8 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 0.2 | GO:0043203 | axon hillock(GO:0043203) |
0.0 | 0.5 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 0.2 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 0.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 0.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.1 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 0.0 | GO:0044299 | C-fiber(GO:0044299) |
0.0 | 0.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 4.9 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958) |
1.2 | 4.6 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
0.4 | 1.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.2 | 2.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.2 | 1.9 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.2 | 0.7 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.2 | 1.1 | GO:0071253 | connexin binding(GO:0071253) |
0.2 | 0.5 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
0.1 | 0.7 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.1 | 0.9 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.1 | 0.3 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.1 | 0.8 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
0.1 | 1.1 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 2.6 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.1 | 0.3 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.1 | 0.4 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589) |
0.1 | 0.4 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.1 | 1.1 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.1 | 0.2 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.1 | 0.3 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.1 | 0.6 | GO:0031432 | titin binding(GO:0031432) |
0.1 | 0.3 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.1 | 1.1 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.1 | 1.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 1.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 0.2 | GO:0097100 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) supercoiled DNA binding(GO:0097100) |
0.1 | 0.5 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.1 | 0.4 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
0.0 | 0.4 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.4 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 0.3 | GO:0034452 | dynactin binding(GO:0034452) |
0.0 | 0.3 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.0 | 0.8 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.4 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
0.0 | 0.3 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.0 | 0.3 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.0 | 0.4 | GO:0048185 | activin binding(GO:0048185) |
0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.5 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
0.0 | 0.3 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.0 | 1.5 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.6 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
0.0 | 0.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.3 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 0.2 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.0 | 0.2 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 0.1 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.0 | 0.1 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.0 | 0.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.1 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.0 | 0.3 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
0.0 | 0.2 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.1 | GO:0070728 | leucine binding(GO:0070728) |
0.0 | 0.2 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 0.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) D-lysine oxidase activity(GO:0043912) |
0.0 | 0.8 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.1 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.0 | 1.2 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.8 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.1 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
0.0 | 0.2 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 2.5 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
0.0 | 0.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.1 | GO:0003905 | alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733) |
0.0 | 0.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.0 | 0.3 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 1.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.6 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 1.1 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |