Motif ID: Nr1h4

Z-value: 0.775


Transcription factors associated with Nr1h4:

Gene SymbolEntrez IDGene Name
Nr1h4 ENSMUSG00000047638.9 Nr1h4



Activity profile for motif Nr1h4.

activity profile for motif Nr1h4


Sorted Z-values histogram for motif Nr1h4

Sorted Z-values for motif Nr1h4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h4

PNG image of the network

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Top targets:


Showing 1 to 20 of 154 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_50752758 2.931 ENSMUST00000034562.7
 Cryab
crystallin, alpha B
chr8_+_94179089 2.775 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr4_+_53440388 2.553 ENSMUST00000102911.3
ENSMUST00000107646.2
 Slc44a1

solute carrier family 44, member 1

chr9_-_42399709 2.413 ENSMUST00000160940.1
 Tecta
tectorin alpha
chr7_-_44670820 2.300 ENSMUST00000048102.7
 Myh14
myosin, heavy polypeptide 14
chr10_-_33995054 1.909 ENSMUST00000164429.1
 Gm17567
predicted gene, 17567
chr5_-_116422858 1.836 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr7_-_105482197 1.584 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr15_+_80287234 1.573 ENSMUST00000160424.1
 Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr5_-_147725988 1.561 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
 Flt1


FMS-like tyrosine kinase 1


chr19_+_5474681 1.521 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
 Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr7_+_19176416 1.492 ENSMUST00000117338.1
 Eml2
echinoderm microtubule associated protein like 2
chr1_+_172341197 1.427 ENSMUST00000056136.3
 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr10_+_13966268 1.351 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr9_+_54538984 1.243 ENSMUST00000060242.5
ENSMUST00000118413.1
 Sh2d7

SH2 domain containing 7

chr2_-_152951547 1.206 ENSMUST00000037715.6
 Dusp15
dual specificity phosphatase-like 15
chr7_-_99695809 1.193 ENSMUST00000107086.2
 Slco2b1
solute carrier organic anion transporter family, member 2b1
chrX_+_73064787 1.132 ENSMUST00000060418.6
 Pnma3
paraneoplastic antigen MA3
chr4_-_141664063 1.071 ENSMUST00000084203.4
 Plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr6_+_4902913 0.971 ENSMUST00000175889.1
ENSMUST00000168998.2
 Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.1 GO:0007605 sensory perception of sound(GO:0007605)
0.5 2.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 2.8 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.5 2.6 GO:0015871 choline transport(GO:0015871)
0.1 2.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 2.1 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.5 1.6 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.3 1.6 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 1.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 1.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.5 1.4 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.5 1.4 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.3 1.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.3 1.1 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 1.0 GO:0070206 protein trimerization(GO:0070206)
0.3 0.9 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 0.9 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.1 0.9 GO:0048664 neuron fate determination(GO:0048664)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 2.9 GO:0097512 cardiac myofibril(GO:0097512)
0.4 2.3 GO:0097513 myosin II filament(GO:0097513)
0.0 1.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.3 1.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 1.4 GO:0097449 astrocyte projection(GO:0097449)
0.0 1.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.3 0.9 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.2 0.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.4 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123) HOPS complex(GO:0030897)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.8 GO:0005507 copper ion binding(GO:0005507)
0.6 2.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 2.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.9 GO:0005080 protein kinase C binding(GO:0005080)
0.4 1.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 1.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.1 0.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.9 GO:0034711 inhibin binding(GO:0034711)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.8 GO:0050897 cobalt ion binding(GO:0050897)