Motif ID: Nkx3-1

Z-value: 0.478


Transcription factors associated with Nkx3-1:

Gene SymbolEntrez IDGene Name
Nkx3-1 ENSMUSG00000022061.8 Nkx3-1



Activity profile for motif Nkx3-1.

activity profile for motif Nkx3-1


Sorted Z-values histogram for motif Nkx3-1

Sorted Z-values for motif Nkx3-1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx3-1

PNG image of the network

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Top targets:


Showing 1 to 20 of 146 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_60963517 1.003 ENSMUST00000115295.2
ENSMUST00000039904.6
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chrX_+_100625737 0.914 ENSMUST00000048962.3
 Kif4
kinesin family member 4
chr19_+_20601958 0.877 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr9_-_124493793 0.823 ENSMUST00000178787.1
 Gm21836
predicted gene, 21836
chr9_+_78191966 0.563 ENSMUST00000034903.5
 Gsta4
glutathione S-transferase, alpha 4
chr5_-_8422582 0.534 ENSMUST00000168500.1
ENSMUST00000002368.9
 Dbf4

DBF4 homolog (S. cerevisiae)

chr1_-_133907053 0.521 ENSMUST00000149380.1
ENSMUST00000124051.2
 Optc

opticin

chr15_-_75048837 0.488 ENSMUST00000179762.1
ENSMUST00000065408.9
 Ly6c1

lymphocyte antigen 6 complex, locus C1

chr8_+_114133557 0.482 ENSMUST00000073521.5
ENSMUST00000066514.6
 Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr10_-_12861735 0.482 ENSMUST00000076817.4
 Utrn
utrophin
chr3_+_30792876 0.477 ENSMUST00000029256.7
 Sec62
SEC62 homolog (S. cerevisiae)
chr9_+_72438534 0.474 ENSMUST00000034746.8
 Mns1
meiosis-specific nuclear structural protein 1
chr18_-_6241486 0.469 ENSMUST00000025083.7
 Kif5b
kinesin family member 5B
chr9_+_72438519 0.458 ENSMUST00000184604.1
 Mns1
meiosis-specific nuclear structural protein 1
chr10_+_94514825 0.445 ENSMUST00000065060.5
 Tmcc3
transmembrane and coiled coil domains 3
chr6_+_128362919 0.438 ENSMUST00000073316.6
 Foxm1
forkhead box M1
chr5_-_21785115 0.409 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
 Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr4_+_32623985 0.400 ENSMUST00000108178.1
 Casp8ap2
caspase 8 associated protein 2
chr2_+_23068168 0.376 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
 Acbd5


acyl-Coenzyme A binding domain containing 5


chr8_+_114133635 0.365 ENSMUST00000147605.1
ENSMUST00000134593.1
 Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 0.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.9 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.1 0.9 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.9 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.3 0.8 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.6 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.2 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.5 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.4 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.4 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.4 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.4 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 0.3 GO:0070093 negative regulation of glucagon secretion(GO:0070093)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.1 0.3 GO:0005712 chiasma(GO:0005712)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.9 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 0.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0036122 BMP binding(GO:0036122)
0.0 0.4 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.1 0.3 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)