Motif ID: Hey1_Myc_Mxi1

Z-value: 0.822

Transcription factors associated with Hey1_Myc_Mxi1:

Gene SymbolEntrez IDGene Name
Hey1 ENSMUSG00000040289.3 Hey1
Mxi1 ENSMUSG00000025025.7 Mxi1
Myc ENSMUSG00000022346.8 Myc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hey1mm10_v2_chr3_-_8667033_8667046-0.281.9e-01Click!
Mycmm10_v2_chr15_+_61985377_61985397-0.154.9e-01Click!
Mxi1mm10_v2_chr19_+_53310495_533105520.087.0e-01Click!


Activity profile for motif Hey1_Myc_Mxi1.

activity profile for motif Hey1_Myc_Mxi1


Sorted Z-values histogram for motif Hey1_Myc_Mxi1

Sorted Z-values for motif Hey1_Myc_Mxi1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hey1_Myc_Mxi1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_77956658 2.826 ENSMUST00000117725.1
ENSMUST00000016696.6
 Foxred2

FAD-dependent oxidoreductase domain containing 2

chr15_-_44788016 2.660 ENSMUST00000090057.4
ENSMUST00000110269.1
 Sybu

syntabulin (syntaxin-interacting)

chr11_+_98348404 2.612 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_-_119422239 2.358 ENSMUST00000038765.5
 Inhbb
inhibin beta-B
chr4_+_148591482 2.346 ENSMUST00000006611.8
 Srm
spermidine synthase
chr17_-_25570678 2.264 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr4_+_101419696 2.225 ENSMUST00000131397.1
ENSMUST00000133055.1
 Ak4

adenylate kinase 4

chr15_+_83791939 2.186 ENSMUST00000172115.1
ENSMUST00000172398.1
 Mpped1

metallophosphoesterase domain containing 1

chr6_+_88724828 2.172 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr6_+_88724412 2.080 ENSMUST00000113585.2
 Mgll
monoglyceride lipase
chr7_-_25658726 2.071 ENSMUST00000071329.6
 Bckdha
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr3_+_104638658 2.069 ENSMUST00000046212.1
 Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr6_+_88724462 1.909 ENSMUST00000113582.1
 Mgll
monoglyceride lipase
chr7_-_63212514 1.812 ENSMUST00000032738.5
 Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
chr8_-_84800024 1.794 ENSMUST00000126806.1
ENSMUST00000076715.6
 Nfix

nuclear factor I/X

chr15_+_81811414 1.787 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr8_+_13159135 1.729 ENSMUST00000033824.6
 Lamp1
lysosomal-associated membrane protein 1
chr12_+_112588753 1.677 ENSMUST00000101029.2
 Inf2
inverted formin, FH2 and WH2 domain containing
chr8_-_84800344 1.631 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chr6_+_54816906 1.528 ENSMUST00000079869.6
 Znrf2
zinc and ring finger 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 433 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 8.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 3.6 GO:0046033 AMP metabolic process(GO:0046033)
0.2 3.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.7 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.8 2.5 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.8 2.4 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.2 2.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.8 2.3 GO:0072034 renal vesicle induction(GO:0072034)
0.6 2.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 2.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.7 2.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 2.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.5 1.9 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.4 1.9 GO:0008355 olfactory learning(GO:0008355)
0.1 1.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.6 1.8 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.4 1.8 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 1.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 1.8 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 1.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 6.9 GO:0043196 varicosity(GO:0043196)
0.0 6.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 3.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 2.7 GO:0097433 dense body(GO:0097433)
0.5 2.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 2.4 GO:0043511 inhibin complex(GO:0043511)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.5 2.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 2.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.1 GO:0044306 neuron projection terminus(GO:0044306)
0.7 2.0 GO:0044194 cytolytic granule(GO:0044194)
0.5 1.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.7 GO:0044391 ribosomal subunit(GO:0044391)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 275 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 8.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 4.0 GO:0004497 monooxygenase activity(GO:0004497)
0.0 4.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 3.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 3.7 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.1 3.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 2.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.8 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.9 2.6 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.5 2.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 2.4 GO:0034711 inhibin binding(GO:0034711)
0.2 2.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.2 2.4 GO:0015026 coreceptor activity(GO:0015026)
0.4 2.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 2.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.5 1.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.3 1.9 GO:0043426 MRF binding(GO:0043426)
0.1 1.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.4 1.8 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)