Motif ID: Hoxa6

Z-value: 0.678


Transcription factors associated with Hoxa6:

Gene SymbolEntrez IDGene Name
Hoxa6 ENSMUSG00000043219.8 Hoxa6



Activity profile for motif Hoxa6.

activity profile for motif Hoxa6


Sorted Z-values histogram for motif Hoxa6

Sorted Z-values for motif Hoxa6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_19103022 8.428 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr16_+_42907563 7.682 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr2_+_71528657 5.913 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr5_-_123141067 3.950 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr1_-_165934900 3.885 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
 Pou2f1


POU domain, class 2, transcription factor 1


chr8_-_84773381 3.534 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr5_+_117841839 3.510 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr13_-_84064772 3.423 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr1_-_163313661 3.350 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
 Prrx1


paired related homeobox 1


chr19_+_26749726 3.117 ENSMUST00000175842.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_+_7069825 2.951 ENSMUST00000056416.7
 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_70474923 2.860 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chr1_+_177445660 2.721 ENSMUST00000077225.6
 Zbtb18
zinc finger and BTB domain containing 18
chr15_-_8710734 2.712 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_-_109170308 2.598 ENSMUST00000036992.7
 Lmo1
LIM domain only 1
chr10_+_97479470 2.533 ENSMUST00000105287.3
 Dcn
decorin
chr9_-_42399709 2.366 ENSMUST00000160940.1
 Tecta
tectorin alpha
chr16_+_43247278 2.352 ENSMUST00000114691.1
ENSMUST00000079441.6
 Zbtb20

zinc finger and BTB domain containing 20

chr9_-_42399915 2.350 ENSMUST00000042190.7
 Tecta
tectorin alpha
chr13_-_97747373 2.338 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 14.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.0 6.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.7 6.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 6.1 GO:0030901 midbrain development(GO:0030901)
2.0 5.9 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.1 5.5 GO:0021766 hippocampus development(GO:0021766)
0.0 4.7 GO:0007160 cell-matrix adhesion(GO:0007160)
1.1 4.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 4.4 GO:1901629 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of presynaptic membrane organization(GO:1901629)
0.6 3.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 3.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.9 3.5 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.3 3.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 2.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.7 2.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.4 2.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 2.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.4 2.3 GO:0006570 tyrosine metabolic process(GO:0006570)
0.2 2.3 GO:0097154 GABAergic neuron differentiation(GO:0097154)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.6 GO:0005667 transcription factor complex(GO:0005667)
0.4 6.7 GO:0071564 npBAF complex(GO:0071564)
0.1 4.4 GO:0045171 intercellular bridge(GO:0045171)
0.3 4.2 GO:0043205 fibril(GO:0043205)
0.1 4.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.6 GO:0031225 anchored component of membrane(GO:0031225)
0.3 3.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 3.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.8 2.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 2.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 1.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.5 GO:0097440 apical dendrite(GO:0097440)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.1 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.1 GO:0005720 nuclear heterochromatin(GO:0005720)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 7.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 4.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.9 4.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 4.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.2 3.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 3.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 2.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.5 GO:0003729 mRNA binding(GO:0003729)
0.6 2.4 GO:0050436 microfibril binding(GO:0050436)
0.2 2.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.5 1.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 1.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 1.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 1.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 1.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.1 GO:0004385 guanylate kinase activity(GO:0004385)