Motif ID: Trp53
Z-value: 0.979
Transcription factors associated with Trp53:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Trp53 | ENSMUSG00000059552.7 | Trp53 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Trp53 | mm10_v2_chr11_+_69580359_69580382 | -0.71 | 1.3e-04 | Click! |
Top targets:
Showing 1 to 20 of 166 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 65 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 6.0 | GO:0090399 | replicative senescence(GO:0090399) |
| 0.1 | 5.1 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 1.2 | 4.7 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.4 | 4.6 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.1 | 3.8 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.7 | 3.7 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 1.0 | 2.9 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.0 | 2.9 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 2.5 | GO:0086016 | AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027) AV node cell to bundle of His cell communication(GO:0086067) |
| 0.2 | 2.1 | GO:0034312 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.1 | 2.1 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.1 | 2.0 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.3 | 1.9 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.4 | 1.7 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.3 | 1.6 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.0 | 1.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 1.5 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.3 | 1.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.0 | 1.2 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.1 | 1.1 | GO:0061436 | establishment of skin barrier(GO:0061436) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 38 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 6.2 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 2.0 | 6.0 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.8 | 5.1 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.3 | 4.7 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 3.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.3 | 2.9 | GO:0031091 | platelet alpha granule(GO:0031091) extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.2 | 2.5 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.1 | 2.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 2.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.3 | 1.8 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.0 | 1.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 1.5 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.3 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 1.3 | GO:0000776 | kinetochore(GO:0000776) |
| 0.3 | 1.2 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 1.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.0 | 1.1 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.9 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.9 | GO:0005871 | kinesin complex(GO:0005871) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 45 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 6.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.4 | 6.0 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 1.2 | 4.7 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.1 | 3.8 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.5 | 3.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 2.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.4 | 2.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.3 | 2.1 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.4 | 2.0 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.1 | 1.8 | GO:1990939 | ATP-dependent microtubule motor activity(GO:1990939) |
| 0.2 | 1.6 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 1.6 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 1.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 1.2 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.2 | 1.0 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.3 | 0.9 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.0 | 0.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.9 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.9 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.9 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
