Motif ID: Prop1

Z-value: 1.029


Transcription factors associated with Prop1:

Gene SymbolEntrez IDGene Name
Prop1 ENSMUSG00000044542.3 Prop1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prop1mm10_v2_chr11_-_50953745_50953768-0.184.0e-01Click!


Activity profile for motif Prop1.

activity profile for motif Prop1


Sorted Z-values histogram for motif Prop1

Sorted Z-values for motif Prop1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prop1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_94875600 7.731 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr10_-_45470201 6.680 ENSMUST00000079390.6
 Lin28b
lin-28 homolog B (C. elegans)
chr16_-_16829276 4.741 ENSMUST00000023468.5
 Spag6
sperm associated antigen 6
chr1_+_107511416 4.513 ENSMUST00000009356.4
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr15_-_56694525 4.425 ENSMUST00000050544.7
 Has2
hyaluronan synthase 2
chr1_+_6734827 3.898 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr18_-_66860458 3.822 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr3_+_146121655 3.736 ENSMUST00000039450.4
 Mcoln3
mucolipin 3
chr14_+_75455957 3.735 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr14_-_40893222 3.302 ENSMUST00000096000.3
 Sh2d4b
SH2 domain containing 4B
chr2_+_61804453 3.227 ENSMUST00000048934.8
 Tbr1
T-box brain gene 1
chr10_-_64090241 3.122 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_-_64090265 3.062 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr2_-_112480817 2.935 ENSMUST00000099589.2
 Chrm5
cholinergic receptor, muscarinic 5
chr17_+_27556613 2.744 ENSMUST00000117600.1
ENSMUST00000114888.3
 Hmga1

high mobility group AT-hook 1

chr17_+_27556668 2.683 ENSMUST00000117254.1
ENSMUST00000118570.1
 Hmga1

high mobility group AT-hook 1

chr17_+_27556641 2.672 ENSMUST00000119486.1
ENSMUST00000118599.1
 Hmga1

high mobility group AT-hook 1

chr10_-_109009055 2.634 ENSMUST00000156979.1
 Syt1
synaptotagmin I
chr9_-_73968901 2.568 ENSMUST00000184666.1
 Unc13c
unc-13 homolog C (C. elegans)
chr9_-_39604124 2.562 ENSMUST00000042485.4
ENSMUST00000141370.1
 AW551984

expressed sequence AW551984


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 6.9 GO:0006284 base-excision repair(GO:0006284)
0.7 6.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 6.2 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.7 4.6 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
1.1 4.4 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.8 3.8 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.7 3.7 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.7 3.7 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 3.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.6 3.2 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.1 3.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.5 2.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 2.8 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 2.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.4 2.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.3 2.6 GO:0005513 detection of calcium ion(GO:0005513)
0.8 2.5 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.6 2.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.5 2.3 GO:0060467 negative regulation of fertilization(GO:0060467)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 8.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 6.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.5 3.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 2.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 2.6 GO:0031045 dense core granule(GO:0031045)
0.2 2.5 GO:0070852 cell body fiber(GO:0070852)
0.5 2.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 1.9 GO:0045179 apical cortex(GO:0045179)
0.1 1.9 GO:0042788 polysomal ribosome(GO:0042788)
0.6 1.7 GO:0032437 cuticular plate(GO:0032437)
0.2 1.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.4 1.2 GO:1990423 RZZ complex(GO:1990423)
0.2 1.2 GO:0033269 internode region of axon(GO:0033269)
0.2 1.1 GO:0002177 manchette(GO:0002177)
0.2 1.1 GO:0008623 CHRAC(GO:0008623)
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 8.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 6.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 6.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
1.1 4.6 GO:0008142 oxysterol binding(GO:0008142)
1.5 4.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.3 3.8 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 3.7 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 3.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 3.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
1.0 2.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 2.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.9 2.6 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.6 2.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.3 2.3 GO:0000150 recombinase activity(GO:0000150)
0.1 2.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.3 GO:0016415 octanoyltransferase activity(GO:0016415)
0.1 1.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)