Motif ID: Foxb1

Z-value: 0.936


Transcription factors associated with Foxb1:

Gene SymbolEntrez IDGene Name
Foxb1 ENSMUSG00000059246.4 Foxb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxb1mm10_v2_chr9_-_69760924_697609400.223.0e-01Click!


Activity profile for motif Foxb1.

activity profile for motif Foxb1


Sorted Z-values histogram for motif Foxb1

Sorted Z-values for motif Foxb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 90 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 4.034 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr3_+_55782500 3.733 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr17_+_93199348 2.939 ENSMUST00000064775.6
 Adcyap1
adenylate cyclase activating polypeptide 1
chr6_+_8948608 2.840 ENSMUST00000160300.1
 Nxph1
neurexophilin 1
chr1_-_158814469 2.828 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr18_-_47333311 2.560 ENSMUST00000126684.1
ENSMUST00000156422.1
 Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr3_+_134236483 2.514 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr6_+_14901344 2.296 ENSMUST00000115477.1
 Foxp2
forkhead box P2
chr2_+_55437100 2.264 ENSMUST00000112633.2
ENSMUST00000112632.1
 Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr13_+_5861489 2.200 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6
chr8_+_58912257 2.074 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr10_+_37139558 2.069 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr3_-_123672321 2.050 ENSMUST00000172537.1
ENSMUST00000029602.6
 Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr19_+_47228804 1.958 ENSMUST00000111807.3
 Neurl1a
neuralized homolog 1A (Drosophila)
chr6_+_5390387 1.764 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr6_-_56362356 1.728 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
 Pde1c



phosphodiesterase 1C



chr17_-_70851710 1.717 ENSMUST00000166395.2
 Tgif1
TGFB-induced factor homeobox 1
chr19_+_20601958 1.556 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr14_-_93888732 1.524 ENSMUST00000068992.2
 Pcdh9
protocadherin 9
chr3_-_123690806 1.497 ENSMUST00000154668.1
 Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 3.1 GO:0043010 camera-type eye development(GO:0043010)
1.0 2.9 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
0.0 2.8 GO:0060349 bone morphogenesis(GO:0060349)
0.1 2.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 2.4 GO:0060539 diaphragm development(GO:0060539)
0.1 2.3 GO:0010107 potassium ion import(GO:0010107)
0.2 2.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 1.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 1.7 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.4 1.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 1.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.3 GO:0051297 centrosome organization(GO:0051297)
0.4 1.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 1.1 GO:0009597 detection of virus(GO:0009597)
0.3 1.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0030315 T-tubule(GO:0030315)
0.1 2.9 GO:0097440 apical dendrite(GO:0097440)
0.1 1.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 1.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 1.5 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 1.3 GO:0030496 midbody(GO:0030496)
0.1 1.1 GO:0070852 cell body fiber(GO:0070852)
0.2 1.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 1.0 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.0 0.8 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 2.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 2.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.0 GO:0045182 translation regulator activity(GO:0045182)
0.0 2.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 1.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.7 GO:0070410 co-SMAD binding(GO:0070410)
0.3 1.6 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 1.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 0.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)