Motif ID: Spi1

Z-value: 1.191


Transcription factors associated with Spi1:

Gene SymbolEntrez IDGene Name
Spi1 ENSMUSG00000002111.8 Spi1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Spi1mm10_v2_chr2_+_91082362_91082390-0.203.6e-01Click!


Activity profile for motif Spi1.

activity profile for motif Spi1


Sorted Z-values histogram for motif Spi1

Sorted Z-values for motif Spi1



Network of associatons between targets according to the STRING database.



First level regulatory network of Spi1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_127725392 3.085 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr19_+_5740885 2.139 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr10_-_27616895 2.075 ENSMUST00000092639.5
 Lama2
laminin, alpha 2
chr5_+_64812336 1.917 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr5_+_89027959 1.741 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr13_-_41487306 1.711 ENSMUST00000021794.6
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr10_-_8518801 1.667 ENSMUST00000061601.7
 Ust
uronyl-2-sulfotransferase
chr5_+_89028035 1.651 ENSMUST00000113216.2
ENSMUST00000134303.1
 Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr16_+_43510267 1.609 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr5_+_111733924 1.609 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr4_-_82705735 1.563 ENSMUST00000155821.1
 Nfib
nuclear factor I/B
chr1_-_55226768 1.532 ENSMUST00000027121.8
ENSMUST00000114428.2
 Rftn2

raftlin family member 2

chr4_-_154636831 1.487 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
 Prdm16






PR domain containing 16






chr1_-_56969864 1.481 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr5_-_32746317 1.463 ENSMUST00000135248.1
 Pisd
phosphatidylserine decarboxylase
chr17_+_3397189 1.461 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr1_-_56969827 1.457 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr5_+_66968961 1.452 ENSMUST00000132991.1
 Limch1
LIM and calponin homology domains 1
chr3_-_101604580 1.436 ENSMUST00000036493.6
 Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr15_-_98567630 1.425 ENSMUST00000012104.6
 Ccnt1
cyclin T1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 577 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.6 GO:0015701 bicarbonate transport(GO:0015701)
0.4 4.3 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 3.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.5 3.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 2.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 2.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.5 2.8 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.2 2.8 GO:0070932 histone H3 deacetylation(GO:0070932)
0.4 2.2 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
0.1 2.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.7 2.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.7 2.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.5 2.0 GO:1903416 response to glycoside(GO:1903416)
0.6 1.9 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 1.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.4 1.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 1.8 GO:1902669 positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.2 1.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 1.8 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.8 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 203 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 6.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 5.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 3.1 GO:0005605 basal lamina(GO:0005605)
0.0 3.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 2.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.3 2.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 1.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.7 GO:0042581 specific granule(GO:0042581)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 1.5 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 329 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 4.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.7 3.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 3.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.8 GO:0000149 SNARE binding(GO:0000149)
0.0 2.8 GO:0008168 methyltransferase activity(GO:0008168)
0.1 2.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.5 2.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 2.2 GO:0004386 helicase activity(GO:0004386)
0.3 2.1 GO:1990239 steroid hormone binding(GO:1990239)
0.1 2.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 2.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 2.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.9 GO:0017166 vinculin binding(GO:0017166)
0.1 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 1.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.7 GO:0005125 cytokine activity(GO:0005125)