Motif ID: Gata4

Z-value: 0.669


Transcription factors associated with Gata4:

Gene SymbolEntrez IDGene Name
Gata4 ENSMUSG00000021944.9 Gata4



Activity profile for motif Gata4.

activity profile for motif Gata4


Sorted Z-values histogram for motif Gata4

Sorted Z-values for motif Gata4



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata4

PNG image of the network

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Top targets:


Showing 1 to 20 of 132 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_135825788 2.106 ENSMUST00000167390.1
 Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr1_-_56969864 2.086 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr6_+_103510874 2.083 ENSMUST00000066905.6
 Chl1
cell adhesion molecule with homology to L1CAM
chr1_-_56969827 1.927 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr1_+_177444653 1.694 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr1_+_45311538 1.579 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr4_-_32923455 1.564 ENSMUST00000035719.4
ENSMUST00000084749.1
 Ankrd6

ankyrin repeat domain 6

chr8_+_84701430 1.553 ENSMUST00000037165.4
 Lyl1
lymphoblastomic leukemia 1
chr1_-_14310198 1.463 ENSMUST00000168081.2
ENSMUST00000027066.6
 Eya1

eyes absent 1 homolog (Drosophila)

chr2_+_4559742 1.459 ENSMUST00000176828.1
 Frmd4a
FERM domain containing 4A
chr3_+_135826075 1.387 ENSMUST00000029810.5
 Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr5_+_64812336 1.375 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr11_+_3330781 1.371 ENSMUST00000136536.1
ENSMUST00000093399.4
 Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr4_-_82705735 1.363 ENSMUST00000155821.1
 Nfib
nuclear factor I/B
chr16_-_23520579 1.194 ENSMUST00000089883.5
 Masp1
mannan-binding lectin serine peptidase 1
chr15_-_50890396 1.176 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr14_-_64455903 1.128 ENSMUST00000067927.7
 Msra
methionine sulfoxide reductase A
chr11_+_3330401 1.085 ENSMUST00000045153.4
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chrX_+_150547375 1.073 ENSMUST00000066337.6
ENSMUST00000112715.1
 Alas2

aminolevulinic acid synthase 2, erythroid

chr15_+_55307743 1.008 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
 Col14a1


collagen, type XIV, alpha 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3 4.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 3.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.4 2.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 2.1 GO:0035640 exploration behavior(GO:0035640)
0.0 1.7 GO:0021766 hippocampus development(GO:0021766)
0.3 1.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.6 GO:0001955 blood vessel maturation(GO:0001955)
0.2 1.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 1.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.3 1.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 1.4 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.2 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 1.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 1.1 GO:0030091 protein repair(GO:0030091)
0.1 1.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 1.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 1.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 1.0 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.0 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.6 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.3 1.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.6 GO:1990246 uniplex complex(GO:1990246)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 3.0 GO:0002020 protease binding(GO:0002020)
0.8 2.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 2.2 GO:0060090 binding, bridging(GO:0060090)
0.1 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 1.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.1 GO:0016594 glycine binding(GO:0016594)
0.1 1.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 1.0 GO:0043015 cAMP binding(GO:0030552) gamma-tubulin binding(GO:0043015)
0.1 0.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 0.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.7 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)