Motif ID: Egr1
Z-value: 1.654
Transcription factors associated with Egr1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Egr1 | ENSMUSG00000038418.7 | Egr1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Egr1 | mm10_v2_chr18_+_34861200_34861215 | -0.12 | 5.8e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 205 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 13.1 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.2 | 7.1 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
| 0.7 | 4.2 | GO:0032796 | uropod organization(GO:0032796) |
| 0.4 | 4.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.2 | 4.0 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.1 | 3.6 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.1 | 3.5 | GO:0045682 | regulation of epidermis development(GO:0045682) |
| 1.1 | 3.4 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.1 | 3.1 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 3.0 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) |
| 0.2 | 2.9 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 2.9 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.4 | 2.5 | GO:0035902 | response to immobilization stress(GO:0035902) |
| 0.1 | 2.5 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.3 | 2.4 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.1 | 2.4 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.7 | 2.2 | GO:0030070 | insulin processing(GO:0030070) |
| 0.5 | 2.2 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.3 | 2.2 | GO:1903423 | positive regulation of synaptic vesicle recycling(GO:1903423) |
| 0.7 | 2.1 | GO:0086017 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) Purkinje myocyte action potential(GO:0086017) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 101 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.9 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.4 | 6.0 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 4.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.2 | 4.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 4.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.3 | 3.9 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 3.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 3.2 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.3 | 2.6 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.1 | 2.6 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.4 | 2.5 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 2.3 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 2.1 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.0 | 2.1 | GO:0030286 | dynein complex(GO:0030286) |
| 0.0 | 2.1 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 2.1 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.6 | 1.9 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 1.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 1.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.4 | 1.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 133 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 12.6 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.1 | 5.3 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.8 | 4.2 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.4 | 4.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 1.1 | 3.4 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
| 0.1 | 3.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 2.9 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.1 | 2.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 2.7 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.1 | 2.6 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 2.5 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.3 | 2.3 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.3 | 2.2 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.3 | 2.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.1 | 2.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 2.0 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.6 | 1.9 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.3 | 1.9 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.1 | 1.9 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.3 | 1.8 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
