Motif ID: Ar

Z-value: 1.256


Transcription factors associated with Ar:

Gene SymbolEntrez IDGene Name
Ar ENSMUSG00000046532.7 Ar



Activity profile for motif Ar.

activity profile for motif Ar


Sorted Z-values histogram for motif Ar

Sorted Z-values for motif Ar



Network of associatons between targets according to the STRING database.



First level regulatory network of Ar

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_5725639 12.662 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr6_+_5725812 12.460 ENSMUST00000115554.1
ENSMUST00000153942.1
Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr3_+_117575268 11.611 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr4_-_136892867 11.428 ENSMUST00000046332.5
C1qc
complement component 1, q subcomponent, C chain
chr3_-_113577743 9.260 ENSMUST00000067980.5
Amy1
amylase 1, salivary
chr3_-_113574758 9.072 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr10_-_117282262 9.040 ENSMUST00000092163.7
Lyz2
lysozyme 2
chr19_+_8664005 8.656 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr12_-_25096080 8.651 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr3_-_113574242 8.646 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr12_+_74297474 8.631 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr14_-_7483762 8.341 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr14_-_5455467 8.004 ENSMUST00000180867.1
Gm3194
predicted gene 3194
chr17_+_56764738 7.571 ENSMUST00000007747.8
Dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr8_+_94179089 7.483 ENSMUST00000034215.6
Mt1
metallothionein 1
chr14_+_3133997 6.350 ENSMUST00000170790.1
Gm10340
predicted gene 10340
chr14_-_6412482 6.310 ENSMUST00000164408.1
Gm3591
predicted gene 3591
chr14_+_5015891 6.149 ENSMUST00000165289.1
ENSMUST00000172110.2
Gm3298

predicted gene 3298

chr14_+_4664192 6.018 ENSMUST00000163525.1
Gm3239
predicted gene 3239
chr14_-_6590613 5.997 ENSMUST00000171706.1
Gm3629
predicted gene 3629
chr14_+_3963547 5.978 ENSMUST00000164696.1
Gm3095
predicted gene 3095
chr13_-_37049203 5.957 ENSMUST00000037491.8
F13a1
coagulation factor XIII, A1 subunit
chr14_+_4023941 5.929 ENSMUST00000096184.4
Gm5796
predicted gene 5796
chrX_-_162565514 5.722 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr14_-_7643972 5.628 ENSMUST00000171360.2
Gm10128
predicted gene 10128
chr14_-_6093942 5.518 ENSMUST00000168733.2
Gm3468
predicted gene 3468
chr17_-_35175995 5.493 ENSMUST00000173324.1
Aif1
allograft inflammatory factor 1
chr15_+_89568322 5.453 ENSMUST00000023295.2
Acr
acrosin prepropeptide
chr8_+_95703037 5.448 ENSMUST00000073139.7
ENSMUST00000080666.7
Ndrg4

N-myc downstream regulated gene 4

chr14_+_5085714 5.444 ENSMUST00000100893.2
Gm8281
predicted gene, 8281
chr14_+_4110526 5.254 ENSMUST00000170207.1
Gm8108
predicted gene 8108
chr14_-_5389049 5.132 ENSMUST00000177986.1
Gm3500
predicted gene 3500
chr14_-_6219210 4.922 ENSMUST00000177670.1
ENSMUST00000168480.3
Gm21560

predicted gene, 21560

chr14_-_6742332 4.816 ENSMUST00000163850.1
Gm3636
predicted gene 3636
chr14_-_5807958 4.763 ENSMUST00000112758.3
ENSMUST00000096171.5
Gm3383

predicted gene 3383

chr19_+_4099998 4.733 ENSMUST00000049658.7
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr14_+_4339563 4.668 ENSMUST00000112778.3
2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr1_-_173942445 4.651 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr10_+_21993890 4.615 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr4_+_12906838 4.439 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr14_-_7022599 4.409 ENSMUST00000100895.3
Gm10406
predicted gene 10406
chr14_-_7090812 4.307 ENSMUST00000179898.1
Gm3696
predicted gene 3696
chr14_-_6287250 4.304 ENSMUST00000170104.2
Gm3411
predicted gene 3411
chr14_-_7100621 4.242 ENSMUST00000167923.1
Gm3696
predicted gene 3696
chr11_-_61453992 4.183 ENSMUST00000060255.7
ENSMUST00000054927.7
ENSMUST00000102661.3
Rnf112


ring finger protein 112


chr7_-_46179929 4.147 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr10_-_86732409 4.116 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr14_-_6875155 4.098 ENSMUST00000170465.2
Gm3636
predicted gene 3636
chr14_-_5741577 4.051 ENSMUST00000177556.1
Gm3373
predicted gene 3373
chr8_+_72319033 4.038 ENSMUST00000067912.7
Klf2
Kruppel-like factor 2 (lung)
chr10_-_32410335 3.985 ENSMUST00000092603.4
Nkain2
Na+/K+ transporting ATPase interacting 2
chr7_+_28982832 3.953 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr7_+_6383310 3.949 ENSMUST00000081022.7
Zfp28
zinc finger protein 28
chr11_+_16752203 3.918 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr2_-_10130638 3.917 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr14_-_6038209 3.885 ENSMUST00000164139.1
Gm8206
predicted gene 8206
chr10_-_78464969 3.778 ENSMUST00000041616.8
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr6_-_6882068 3.620 ENSMUST00000142635.1
ENSMUST00000052609.8
Dlx5

distal-less homeobox 5

chr10_+_127078886 3.615 ENSMUST00000039259.6
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr16_-_5222257 3.604 ENSMUST00000050160.4
AU021092
expressed sequence AU021092
chr11_+_78322965 3.589 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr12_-_111908040 3.555 ENSMUST00000163747.2
ENSMUST00000054815.7
Ppp1r13b

protein phosphatase 1, regulatory (inhibitor) subunit 13B

chr14_+_4415448 3.538 ENSMUST00000168866.1
Gm3164
predicted gene 3164
chr14_-_5260580 3.457 ENSMUST00000164544.1
Gm3526
predicted gene 3526
chr19_-_45812291 3.450 ENSMUST00000086993.4
Kcnip2
Kv channel-interacting protein 2
chr2_+_4559742 3.432 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr14_-_5373401 3.379 ENSMUST00000178058.1
Gm3500
predicted gene 3500
chr5_-_115652974 3.321 ENSMUST00000121746.1
ENSMUST00000118576.1
Ccdc64

coiled-coil domain containing 64

chr5_+_17574726 3.312 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_-_122697603 3.293 ENSMUST00000071235.4
Gm10064
predicted gene 10064
chr11_+_105975204 3.213 ENSMUST00000001964.7
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr14_-_5725943 3.207 ENSMUST00000169087.2
Gm3373
predicted gene 3373
chr5_+_110879788 3.165 ENSMUST00000156290.2
ENSMUST00000040111.9
Ttc28

tetratricopeptide repeat domain 28

chr7_-_16476765 3.154 ENSMUST00000002053.8
Npas1
neuronal PAS domain protein 1
chr10_-_78464853 3.115 ENSMUST00000105385.1
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr15_+_102102926 3.099 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr15_+_80097866 3.038 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr11_+_94936224 2.991 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr6_-_126645784 2.989 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr2_+_30266513 2.948 ENSMUST00000091132.6
Phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr2_-_24935148 2.940 ENSMUST00000102935.3
ENSMUST00000133934.1
ENSMUST00000028349.7
Arrdc1


arrestin domain containing 1


chr9_+_72985568 2.897 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
Ccpg1


cell cycle progression 1


chr7_-_126676357 2.892 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
Sult1a1


sulfotransferase family 1A, phenol-preferring, member 1


chr2_+_152427639 2.884 ENSMUST00000128737.1
6820408C15Rik
RIKEN cDNA 6820408C15 gene
chr6_-_122801639 2.850 ENSMUST00000165884.1
Slc2a3
solute carrier family 2 (facilitated glucose transporter), member 3
chr17_+_48932368 2.848 ENSMUST00000046254.2
Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr6_+_55203381 2.837 ENSMUST00000053094.7
Fam188b
family with sequence similarity 188, member B
chr8_-_54718664 2.827 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chrX_-_8132770 2.788 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
Wdr13



WD repeat domain 13



chr4_+_138395198 2.761 ENSMUST00000062902.6
AB041806
hypothetical protein, MNCb-2457
chr14_-_6390319 2.753 ENSMUST00000100900.3
Gm16440
predicted gene 16440
chr6_+_135362931 2.710 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr14_-_6840306 2.620 ENSMUST00000179296.1
ENSMUST00000166895.1
Gm3642

predicted gene 3642

chr2_-_26380600 2.617 ENSMUST00000114115.2
ENSMUST00000035427.4
Snapc4

small nuclear RNA activating complex, polypeptide 4

chr8_+_84148252 2.600 ENSMUST00000093375.4
4930432K21Rik
RIKEN cDNA 4930432K21 gene
chr10_-_95415484 2.585 ENSMUST00000172070.1
ENSMUST00000150432.1
Socs2

suppressor of cytokine signaling 2

chr14_-_6537210 2.582 ENSMUST00000178896.1
ENSMUST00000164917.1
ENSMUST00000163636.1
Gm8356


predicted gene 8356


chr14_+_3188255 2.552 ENSMUST00000100920.3
ENSMUST00000171150.1
ENSMUST00000166275.1
Gm5795


predicted gene 5795


chr18_+_64254359 2.547 ENSMUST00000025477.7
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr8_-_54724317 2.481 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr13_+_67128219 2.470 ENSMUST00000052716.7
Zfp759
zinc finger protein 759
chr16_+_36934976 2.469 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr4_-_127313980 2.437 ENSMUST00000053753.7
Gja4
gap junction protein, alpha 4
chr18_+_33794882 2.420 ENSMUST00000146010.2
2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr6_+_29279587 2.377 ENSMUST00000167131.1
Fam71f2
family with sequence similarity 71, member F2
chr2_+_55435918 2.374 ENSMUST00000067101.3
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr9_+_72985410 2.372 ENSMUST00000037977.8
Ccpg1
cell cycle progression 1
chr8_+_25532125 2.370 ENSMUST00000167764.1
Fgfr1
fibroblast growth factor receptor 1
chr7_-_137410717 2.360 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr8_-_115707778 2.352 ENSMUST00000109104.1
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr9_-_57467985 2.345 ENSMUST00000046587.6
Scamp5
secretory carrier membrane protein 5
chr14_-_6973818 2.337 ENSMUST00000166618.1
Gm6356
predicted gene 6356
chr7_-_19861299 2.328 ENSMUST00000014830.7
Ceacam16
carcinoembryonic antigen-related cell adhesion molecule 16
chr9_-_75599124 2.293 ENSMUST00000098552.2
Tmod2
tropomodulin 2
chr1_-_180193475 2.291 ENSMUST00000160482.1
ENSMUST00000170472.1
Adck3

aarF domain containing kinase 3

chr15_-_102524615 2.279 ENSMUST00000023814.7
Npff
neuropeptide FF-amide peptide precursor
chr9_-_106685653 2.274 ENSMUST00000163441.1
Tex264
testis expressed gene 264
chr2_-_24935054 2.227 ENSMUST00000132074.1
Arrdc1
arrestin domain containing 1
chr13_-_24937585 2.218 ENSMUST00000037615.6
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr14_+_32159865 2.207 ENSMUST00000163336.1
ENSMUST00000169722.1
ENSMUST00000168385.1
Ncoa4


nuclear receptor coactivator 4


chr7_-_97417730 2.173 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr14_-_26066961 2.167 ENSMUST00000100818.5
Tmem254c
transmembrane protein 254c
chr1_-_54194048 2.166 ENSMUST00000120904.1
Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr11_-_98053415 2.160 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr10_-_83533383 2.153 ENSMUST00000146640.1
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr12_+_84100654 2.148 ENSMUST00000056822.3
Acot6
acyl-CoA thioesterase 6
chr18_+_33794915 2.139 ENSMUST00000179138.1
2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr4_+_21848039 2.112 ENSMUST00000098238.2
ENSMUST00000108229.1
Sfrs18

serine/arginine-rich splicing factor 18

chr2_+_163994960 2.109 ENSMUST00000018470.3
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr15_+_100334929 2.093 ENSMUST00000075420.4
Mettl7a3
methyltransferase like 7A3
chr9_+_72985504 2.091 ENSMUST00000156879.1
Ccpg1
cell cycle progression 1
chr3_-_40846847 2.090 ENSMUST00000026859.5
Mfsd8
major facilitator superfamily domain containing 8
chr15_-_58214882 2.087 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr7_-_126676428 2.067 ENSMUST00000106373.1
Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr10_-_33624587 2.058 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr14_-_5633028 2.041 ENSMUST00000170469.1
Gm8265
predicted gene 8265
chr17_+_33810515 1.964 ENSMUST00000048560.4
ENSMUST00000172649.1
ENSMUST00000173789.1
Kank3


KN motif and ankyrin repeat domains 3


chr13_+_84222286 1.870 ENSMUST00000057495.8
Tmem161b
transmembrane protein 161B
chr10_+_79988584 1.832 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr14_-_19549958 1.826 ENSMUST00000164372.1
Gm2244
predicted gene 2244
chr11_-_110251736 1.824 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr3_-_84259812 1.822 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr7_+_25619404 1.819 ENSMUST00000077338.5
ENSMUST00000085953.3
Atp5sl

ATP5S-like

chr11_-_46052311 1.807 ENSMUST00000093169.2
Gm12166
predicted gene 12166
chr8_-_54724474 1.752 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr4_+_99715640 1.723 ENSMUST00000097961.2
ENSMUST00000107004.2
ENSMUST00000139799.1
Alg6


asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)


chr3_-_122984404 1.701 ENSMUST00000090379.2
Usp53
ubiquitin specific peptidase 53
chr2_-_11502025 1.680 ENSMUST00000114846.2
Pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr7_+_12922290 1.648 ENSMUST00000108539.1
ENSMUST00000004554.7
ENSMUST00000147435.1
ENSMUST00000137329.1
Rps5



ribosomal protein S5



chr2_-_12301914 1.623 ENSMUST00000028106.4
Itga8
integrin alpha 8
chr6_+_94500313 1.595 ENSMUST00000061118.8
Slc25a26
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
chr15_+_85037062 1.589 ENSMUST00000023069.7
Fam118a
family with sequence similarity 118, member A
chr10_+_116143881 1.556 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr17_+_56673225 1.520 ENSMUST00000002445.8
Ranbp3
RAN binding protein 3
chr2_+_127070646 1.503 ENSMUST00000002064.8
ENSMUST00000135529.1
ENSMUST00000110389.3
Blvra


biliverdin reductase A


chr15_-_79742518 1.481 ENSMUST00000089311.4
ENSMUST00000046259.7
Sun2

Sad1 and UNC84 domain containing 2

chr11_+_86484647 1.475 ENSMUST00000020827.6
Rnft1
ring finger protein, transmembrane 1
chr17_-_25433263 1.461 ENSMUST00000159623.1
Cacna1h
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr5_+_16553488 1.456 ENSMUST00000030683.3
Hgf
hepatocyte growth factor
chr15_-_58847321 1.441 ENSMUST00000075109.5
Ube2d4
ubiquitin-conjugating enzyme E2D 4
chr7_+_41633531 1.433 ENSMUST00000100275.3
ENSMUST00000131180.1
ENSMUST00000140964.1
ENSMUST00000045720.7
ENSMUST00000098508.2
Zfp788




zinc finger protein 788




chr15_-_74997634 1.425 ENSMUST00000023248.6
Ly6a
lymphocyte antigen 6 complex, locus A
chr19_+_5474681 1.419 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr9_+_56865104 1.413 ENSMUST00000035661.5
Cspg4
chondroitin sulfate proteoglycan 4
chrX_+_136741821 1.403 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr14_+_3224440 1.387 ENSMUST00000112797.4
D830030K20Rik
RIKEN cDNA D830030K20 gene
chr16_-_95459245 1.363 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr1_-_160792908 1.357 ENSMUST00000028049.7
Rabgap1l
RAB GTPase activating protein 1-like
chr19_-_45046614 1.338 ENSMUST00000145391.1
Pdzd7
PDZ domain containing 7
chr13_-_106936907 1.337 ENSMUST00000080856.7
Ipo11
importin 11
chr8_-_105568298 1.314 ENSMUST00000005849.5
Agrp
agouti related protein
chr4_+_88094599 1.310 ENSMUST00000097992.3
Focad
focadhesin
chr14_+_3846245 1.304 ENSMUST00000180934.1
Gm3033
predicted gene 3033
chr17_+_47593516 1.301 ENSMUST00000182874.1
Ccnd3
cyclin D3
chr4_+_42949814 1.292 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr13_-_67755132 1.272 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr12_-_4477138 1.261 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr6_+_52714219 1.243 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr11_-_86671169 1.243 ENSMUST00000143991.1
Vmp1
vacuole membrane protein 1
chr17_+_34187545 1.241 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_-_11502067 1.237 ENSMUST00000028114.6
ENSMUST00000049849.6
Pfkfb3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

chr3_-_116253467 1.233 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr13_+_55693082 1.231 ENSMUST00000057844.8
B230219D22Rik
RIKEN cDNA B230219D22 gene
chr15_-_79742493 1.228 ENSMUST00000100439.3
Sun2
Sad1 and UNC84 domain containing 2
chr2_-_91070283 1.225 ENSMUST00000111436.2
ENSMUST00000073575.5
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr15_+_102503722 1.224 ENSMUST00000096145.4
Gm10337
predicted gene 10337
chr2_-_132029845 1.205 ENSMUST00000028814.8
Rassf2
Ras association (RalGDS/AF-6) domain family member 2
chr11_-_48946148 1.197 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr14_+_4892416 1.195 ENSMUST00000164459.1
Gm3278
predicted gene 3278
chr17_+_33524170 1.195 ENSMUST00000087623.6
Adamts10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
chr14_-_7450917 1.165 ENSMUST00000169555.1
Gm3755
predicted gene 3755
chr2_-_109280718 1.163 ENSMUST00000147770.1
Mettl15
methyltransferase like 15
chr2_+_25456830 1.159 ENSMUST00000114265.2
ENSMUST00000102918.2
Clic3

chloride intracellular channel 3

chr13_+_13954614 1.154 ENSMUST00000099747.3
B3galnt2
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2
chr17_+_37270214 1.140 ENSMUST00000038580.6
H2-M3
histocompatibility 2, M region locus 3
chr17_+_25823626 1.137 ENSMUST00000026833.5
Wdr24
WD repeat domain 24
chr18_+_36348653 1.127 ENSMUST00000050584.3
Cystm1
cysteine-rich transmembrane module containing 1
chr8_-_60983215 1.117 ENSMUST00000004430.7
ENSMUST00000110301.1
ENSMUST00000093490.2
Clcn3


chloride channel 3


chr13_-_104863883 1.116 ENSMUST00000043061.4
Fam159b
family with sequence similarity 159, member B
chr5_-_74531619 1.079 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Scfd2



Sec1 family domain containing 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
2.3 6.9 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
2.3 25.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
2.0 6.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
1.8 7.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.8 5.5 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
1.8 5.5 GO:0007341 penetration of zona pellucida(GO:0007341)
1.7 8.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.7 8.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
1.6 11.4 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
1.4 4.1 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
1.2 3.6 GO:0060166 olfactory pit development(GO:0060166)
1.2 3.6 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
1.2 4.7 GO:0060025 regulation of synaptic activity(GO:0060025)
1.1 7.5 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
1.0 3.0 GO:0050975 sensory perception of touch(GO:0050975)
0.9 2.6 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.8 4.0 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.8 2.4 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.8 3.9 GO:0070459 prolactin secretion(GO:0070459)
0.7 2.2 GO:0006083 acetate metabolic process(GO:0006083)
0.7 2.2 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.7 3.6 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.7 2.8 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.7 3.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.7 2.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.6 2.5 GO:1990743 protein sialylation(GO:1990743)
0.6 1.1 GO:0002481 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.6 2.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.6 3.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.5 1.0 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.5 1.5 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.5 3.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 3.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4 5.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.4 0.8 GO:2000282 regulation of cellular amino acid biosynthetic process(GO:2000282)
0.4 1.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.4 2.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 1.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.4 1.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.4 4.0 GO:0051923 sulfation(GO:0051923)
0.4 3.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 2.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 2.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.3 2.3 GO:0070253 somatostatin secretion(GO:0070253)
0.3 1.6 GO:0051182 coenzyme transport(GO:0051182)
0.3 1.2 GO:0061743 motor learning(GO:0061743)
0.3 4.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 0.9 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.3 1.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 1.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.3 0.8 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 1.0 GO:0050904 diapedesis(GO:0050904)
0.2 1.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 1.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 0.7 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.2 1.3 GO:0008343 adult feeding behavior(GO:0008343)
0.2 2.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.3 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.2 0.8 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 5.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 1.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 0.7 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.2 1.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 0.8 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 3.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 3.2 GO:0042711 maternal behavior(GO:0042711)
0.2 2.6 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 0.3 GO:0035811 negative regulation of urine volume(GO:0035811)
0.2 0.5 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 1.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 19.4 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.1 2.7 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 4.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 4.5 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.1 1.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 1.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.2 GO:0070475 rRNA base methylation(GO:0070475)
0.1 2.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.8 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 1.0 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 3.6 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 2.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 4.7 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.6 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 2.2 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 3.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 2.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 1.4 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.5 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 2.4 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.8 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 2.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.1 0.9 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 1.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 5.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 3.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.0 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 1.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 2.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.3 GO:0090148 membrane fission(GO:0090148)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0051693 actin filament capping(GO:0051693)
0.0 2.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.7 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.4 GO:0048747 muscle fiber development(GO:0048747)
0.0 4.0 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 25.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
1.8 9.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.0 4.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.0 3.0 GO:0005584 collagen type I trimer(GO:0005584)
1.0 3.9 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.4 3.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.4 8.7 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.3 GO:0002141 stereocilia ankle link(GO:0002141)
0.3 2.2 GO:0042825 TAP complex(GO:0042825)
0.3 5.5 GO:0001891 phagocytic cup(GO:0001891)
0.3 1.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 0.8 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.3 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.2 2.3 GO:0032426 stereocilium tip(GO:0032426)
0.2 21.6 GO:0072562 blood microparticle(GO:0072562)
0.2 0.8 GO:0071797 LUBAC complex(GO:0071797)
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 2.2 GO:0044754 autolysosome(GO:0044754)
0.2 2.5 GO:0005922 connexon complex(GO:0005922)
0.2 3.2 GO:0097225 sperm midpiece(GO:0097225)
0.2 3.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 2.8 GO:0002080 acrosomal membrane(GO:0002080)
0.1 3.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 0.8 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.2 GO:0070820 tertiary granule(GO:0070820)
0.1 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 2.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 5.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 1.1 GO:0042581 specific granule(GO:0042581)
0.1 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 4.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.7 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.1 GO:0042611 MHC protein complex(GO:0042611)
0.1 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 3.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.9 GO:0005682 U5 snRNP(GO:0005682)
0.0 4.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 2.3 GO:0042641 actomyosin(GO:0042641)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.8 GO:0030017 sarcomere(GO:0030017) contractile fiber part(GO:0044449)
0.0 3.6 GO:0030424 axon(GO:0030424)
0.0 2.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.4 GO:0043235 receptor complex(GO:0043235)
0.0 14.2 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 3.6 GO:0005925 focal adhesion(GO:0005925)
0.0 4.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 27.0 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
3.0 9.0 GO:0003796 lysozyme activity(GO:0003796)
2.3 6.9 GO:0031403 lithium ion binding(GO:0031403)
1.8 5.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
1.7 8.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.7 5.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.5 6.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.5 25.1 GO:0045504 dynein heavy chain binding(GO:0045504)
1.3 3.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.8 3.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.7 2.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.7 2.8 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.7 3.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.6 3.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 4.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.6 2.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.5 2.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 2.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 4.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 2.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 3.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.4 1.5 GO:0004074 biliverdin reductase activity(GO:0004074)
0.4 1.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 5.5 GO:0005537 mannose binding(GO:0005537)
0.3 2.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 3.6 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.3 4.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 1.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 1.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.3 2.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 3.6 GO:0043495 protein anchor(GO:0043495)
0.3 3.3 GO:0038191 neuropilin binding(GO:0038191)
0.3 2.3 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.2 1.3 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 3.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 2.1 GO:0050815 phosphoserine binding(GO:0050815)
0.2 3.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 3.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.8 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 0.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.1 5.9 GO:0005507 copper ion binding(GO:0005507)
0.1 2.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 2.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 4.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 2.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 2.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 6.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 0.6 GO:0000182 rDNA binding(GO:0000182)
0.1 0.2 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.1 0.3 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 4.4 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.7 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 1.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 4.0 GO:0001047 core promoter binding(GO:0001047)
0.0 2.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 4.9 GO:0003924 GTPase activity(GO:0003924)
0.0 1.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.7 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 2.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 2.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 4.0 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 5.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.2 6.0 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 13.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 8.8 PID_FOXO_PATHWAY FoxO family signaling
0.1 5.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 16.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.4 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 4.4 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 1.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 2.4 ST_ADRENERGIC Adrenergic Pathway
0.1 1.0 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 3.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 0.8 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.6 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.5 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 0.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 2.4 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.1 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.0 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.0 6.0 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.7 5.0 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.7 8.7 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 2.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 3.0 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 6.0 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.2 2.2 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 2.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.2 6.0 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 21.7 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 8.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 5.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.5 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.6 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.6 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 2.2 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.0 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 1.6 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.6 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 3.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.0 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.7 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 2.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.6 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.0 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.9 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism