Motif ID: Arid5b

Z-value: 0.263


Transcription factors associated with Arid5b:

Gene SymbolEntrez IDGene Name
Arid5b ENSMUSG00000019947.9 Arid5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid5bmm10_v2_chr10_-_68278713_68278735-0.132.6e-01Click!


Activity profile for motif Arid5b.

activity profile for motif Arid5b


Sorted Z-values histogram for motif Arid5b

Sorted Z-values for motif Arid5b



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_6980376 1.572 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr9_+_21196705 1.245 ENSMUST00000003395.9
 Pde4a
phosphodiesterase 4A, cAMP specific
chr10_-_109010955 1.063 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr3_-_95882031 0.765 ENSMUST00000161994.1
 Gm129
predicted gene 129
chr9_+_112227443 0.706 ENSMUST00000161216.1
 2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr9_+_87022014 0.663 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
 Cyb5r4


cytochrome b5 reductase 4


chr15_-_13173607 0.662 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr18_+_62662108 0.662 ENSMUST00000163259.1
 Gm17732
predicted gene, 17732
chr8_-_119840522 0.615 ENSMUST00000168698.1
ENSMUST00000034285.6
 Cotl1

coactosin-like 1 (Dictyostelium)

chr12_-_24680890 0.543 ENSMUST00000156453.2
 Cys1
cystin 1
chr3_-_19264959 0.523 ENSMUST00000121951.1
 Pde7a
phosphodiesterase 7A
chr5_-_31697598 0.494 ENSMUST00000031018.7
 Rbks
ribokinase
chr3_-_95882193 0.470 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
 Gm129


predicted gene 129


chr7_-_67645195 0.456 ENSMUST00000032775.5
ENSMUST00000053950.2
 Lrrc28

leucine rich repeat containing 28

chr9_-_45984816 0.445 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr13_+_21735055 0.431 ENSMUST00000087714.4
 Hist1h4j
histone cluster 1, H4j
chr1_+_180568913 0.421 ENSMUST00000027777.6
 Parp1
poly (ADP-ribose) polymerase family, member 1
chrX_-_157492280 0.413 ENSMUST00000112529.1
 Sms
spermine synthase
chr8_-_79399513 0.409 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
 Smad1


SMAD family member 1


chr16_+_32431225 0.391 ENSMUST00000115140.1
 Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr6_+_120666388 0.379 ENSMUST00000112686.1
 Cecr2
cat eye syndrome chromosome region, candidate 2
chr10_+_14523062 0.363 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr4_+_132638987 0.362 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
 Eya3




eyes absent 3 homolog (Drosophila)




chr10_+_127420867 0.336 ENSMUST00000064793.6
 R3hdm2
R3H domain containing 2
chr15_+_37233036 0.328 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
 Grhl2


grainyhead-like 2 (Drosophila)


chr3_-_95882232 0.321 ENSMUST00000161866.1
 Gm129
predicted gene 129
chr12_-_91746020 0.309 ENSMUST00000166967.1
 Ston2
stonin 2
chr9_-_106789130 0.308 ENSMUST00000046502.5
 Rad54l2
RAD54 like 2 (S. cerevisiae)
chr12_-_10900296 0.304 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr12_+_110601439 0.301 ENSMUST00000018851.7
 Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr15_-_44428303 0.269 ENSMUST00000038719.6
 Nudcd1
NudC domain containing 1
chr13_+_109685994 0.257 ENSMUST00000074103.5
 Pde4d
phosphodiesterase 4D, cAMP specific
chr6_+_97210689 0.255 ENSMUST00000044681.6
 Arl6ip5
ADP-ribosylation factor-like 6 interacting protein 5
chr5_-_131538687 0.235 ENSMUST00000161374.1
 Auts2
autism susceptibility candidate 2
chr10_+_116143881 0.215 ENSMUST00000105271.2
 Ptprr
protein tyrosine phosphatase, receptor type, R
chr4_-_129662442 0.213 ENSMUST00000003828.4
 Kpna6
karyopherin (importin) alpha 6
chr1_-_31222604 0.197 ENSMUST00000127775.1
 4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr14_-_47394253 0.187 ENSMUST00000177822.1
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr16_+_44943737 0.184 ENSMUST00000114622.3
ENSMUST00000166731.1
 Cd200r3

CD200 receptor 3

chr5_+_115908644 0.167 ENSMUST00000141101.1
 Cit
citron
chr4_+_43631935 0.160 ENSMUST00000030191.8
 Npr2
natriuretic peptide receptor 2
chr3_-_89998656 0.159 ENSMUST00000079724.4
 Hax1
HCLS1 associated X-1
chr2_+_76650264 0.144 ENSMUST00000099986.2
 Dfnb59
deafness, autosomal recessive 59 (human)
chr8_+_104831572 0.144 ENSMUST00000059449.6
 Ces2b
carboxyesterase 2B
chr4_+_43632185 0.143 ENSMUST00000107874.2
 Npr2
natriuretic peptide receptor 2
chr2_-_151744142 0.134 ENSMUST00000109869.1
 Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr10_+_94576254 0.128 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chrM_+_8600 0.125 ENSMUST00000082409.1
 mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr1_+_163779575 0.123 ENSMUST00000027877.6
ENSMUST00000077642.5
 Kifap3

kinesin-associated protein 3

chr13_+_23533869 0.112 ENSMUST00000073261.2
 Hist1h2af
histone cluster 1, H2af
chrX_+_140456613 0.100 ENSMUST00000033809.3
 Prps1
phosphoribosyl pyrophosphate synthetase 1
chr15_-_55548164 0.095 ENSMUST00000165356.1
 Mrpl13
mitochondrial ribosomal protein L13
chr4_-_75278246 0.092 ENSMUST00000030103.8
 Tmem261
transmembrane protein 261
chr11_+_108682602 0.082 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
 Cep112


centrosomal protein 112


chr1_+_88227005 0.079 ENSMUST00000061013.6
ENSMUST00000113130.1
 Mroh2a

maestro heat-like repeat family member 2A

chr4_-_150909428 0.074 ENSMUST00000128075.1
ENSMUST00000105674.1
ENSMUST00000105673.1
 Park7


Parkinson disease (autosomal recessive, early onset) 7


chr14_-_52213379 0.073 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr2_-_84678828 0.072 ENSMUST00000111665.1
 Tmx2
thioredoxin-related transmembrane protein 2
chr3_+_95588990 0.065 ENSMUST00000177399.1
 Golph3l
golgi phosphoprotein 3-like
chr11_-_109298090 0.058 ENSMUST00000106704.2
 Rgs9
regulator of G-protein signaling 9
chr11_-_110251736 0.058 ENSMUST00000044003.7
 Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chrX_+_47912387 0.057 ENSMUST00000001202.8
ENSMUST00000115020.1
 Ocrl

oculocerebrorenal syndrome of Lowe

chr8_+_34115030 0.054 ENSMUST00000095345.3
 Mboat4
membrane bound O-acyltransferase domain containing 4
chr4_+_105157339 0.050 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chrX_-_101222426 0.044 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
 Snx12


sorting nexin 12


chr18_+_23415400 0.032 ENSMUST00000115832.2
ENSMUST00000047954.7
 Dtna

dystrobrevin alpha

chr5_+_31494736 0.029 ENSMUST00000076949.6
ENSMUST00000117700.1
 Gpn1

GPN-loop GTPase 1

chr3_+_95588960 0.020 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
 Golph3l


golgi phosphoprotein 3-like


chr18_-_25753852 0.019 ENSMUST00000025117.6
ENSMUST00000115816.2
 Celf4

CUGBP, Elav-like family member 4

chr18_-_15063560 0.017 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr3_-_19265007 0.017 ENSMUST00000091314.4
 Pde7a
phosphodiesterase 7A
chr9_+_122117338 0.013 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
 Snrk


SNF related kinase


chr3_+_95588928 0.009 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
 Golph3l


golgi phosphoprotein 3-like



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.1 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.5 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.3 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.1 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 1.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.4 GO:0001842 neural fold formation(GO:0001842)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) positive regulation of superoxide dismutase activity(GO:1901671) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of removal of superoxide radicals(GO:1904833) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.7 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.0 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0090537 CERF complex(GO:0090537)
0.1 1.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 2.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.1 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends