Motif ID: Arnt

Z-value: 0.534


Transcription factors associated with Arnt:

Gene SymbolEntrez IDGene Name
Arnt ENSMUSG00000015522.12 Arnt

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arntmm10_v2_chr3_+_95434386_95434428-0.386.2e-04Click!


Activity profile for motif Arnt.

activity profile for motif Arnt


Sorted Z-values histogram for motif Arnt

Sorted Z-values for motif Arnt



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_125490688 6.860 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr19_+_43440404 2.810 ENSMUST00000165311.1
 Cnnm1
cyclin M1
chr15_+_98167806 2.475 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr11_+_98937669 2.096 ENSMUST00000107475.2
ENSMUST00000068133.3
 Rara

retinoic acid receptor, alpha

chr11_+_82388900 2.040 ENSMUST00000054245.4
ENSMUST00000092852.2
 Tmem132e

transmembrane protein 132E

chr12_-_67222549 1.940 ENSMUST00000037181.8
 Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr5_-_106458440 1.918 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr15_+_74721193 1.854 ENSMUST00000070923.1
 Them6
thioesterase superfamily member 6
chr15_-_79834323 1.853 ENSMUST00000177316.2
ENSMUST00000175858.2
 Nptxr

neuronal pentraxin receptor

chr5_+_28165690 1.832 ENSMUST00000036177.7
 En2
engrailed 2
chr12_-_56535047 1.804 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr3_-_107458895 1.779 ENSMUST00000009617.8
 Kcnc4
potassium voltage gated channel, Shaw-related subfamily, member 4
chr12_+_95692212 1.644 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr5_-_45639501 1.623 ENSMUST00000016023.7
 Fam184b
family with sequence similarity 184, member B
chr11_+_101316200 1.604 ENSMUST00000142640.1
ENSMUST00000019470.7
 Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr19_+_41981709 1.502 ENSMUST00000026170.1
 Ubtd1
ubiquitin domain containing 1
chr13_-_38658991 1.474 ENSMUST00000001757.7
 Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr17_+_27556641 1.470 ENSMUST00000119486.1
ENSMUST00000118599.1
 Hmga1

high mobility group AT-hook 1

chr2_-_178414460 1.464 ENSMUST00000058678.4
 Ppp1r3d
protein phosphatase 1, regulatory subunit 3D
chr17_-_65613521 1.423 ENSMUST00000024897.8
 Vapa
vesicle-associated membrane protein, associated protein A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.9 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 4.0 GO:0006284 base-excision repair(GO:0006284)
0.1 2.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 2.8 GO:0009649 entrainment of circadian clock(GO:0009649)
0.3 2.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.7 2.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.6 1.8 GO:0021759 globus pallidus development(GO:0021759)
0.4 1.8 GO:0045759 negative regulation of action potential(GO:0045759)
0.3 1.8 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 1.8 GO:1990403 embryonic brain development(GO:1990403)
0.2 1.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 1.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 1.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 1.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 1.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 1.4 GO:0001709 cell fate determination(GO:0001709)
0.0 1.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.4 1.3 GO:0070889 platelet alpha granule organization(GO:0070889)
0.3 1.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.4 1.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 5.8 GO:0000139 Golgi membrane(GO:0000139)
0.6 4.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.4 1.6 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.5 GO:0042587 glycogen granule(GO:0042587)
0.2 1.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4 1.2 GO:0044194 cytolytic granule(GO:0044194)
0.2 1.2 GO:0097452 GAIT complex(GO:0097452)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.1 GO:0045120 pronucleus(GO:0045120)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.1 0.9 GO:0032009 early phagosome(GO:0032009)
0.1 0.8 GO:0033391 chromatoid body(GO:0033391)
0.1 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0070469 respiratory chain(GO:0070469)
0.1 0.7 GO:0034715 pICln-Sm protein complex(GO:0034715)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 7.7 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.4 4.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5 2.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 2.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.5 1.9 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 1.9 GO:0070888 E-box binding(GO:0070888)
0.3 1.8 GO:0043426 MRF binding(GO:0043426)
0.2 1.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 1.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 1.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.4 1.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.2 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.1 GO:1990715 mRNA CDS binding(GO:1990715)

Gene overrepresentation in C2:CP category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 3.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.9 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.1 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 4.1 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5 4.0 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.5 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.2 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.9 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 1.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 1.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.4 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.3 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.1 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.0 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL