Motif ID: Arnt2

Z-value: 0.311


Transcription factors associated with Arnt2:

Gene SymbolEntrez IDGene Name
Arnt2 ENSMUSG00000015709.8 Arnt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arnt2mm10_v2_chr7_-_84409959_844100020.208.8e-02Click!


Activity profile for motif Arnt2.

activity profile for motif Arnt2


Sorted Z-values histogram for motif Arnt2

Sorted Z-values for motif Arnt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 43 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_46890405 2.532 ENSMUST00000086675.3
 A330017A19Rik
RIKEN cDNA A330017A19 gene
chr13_+_118714678 1.699 ENSMUST00000022246.8
 Fgf10
fibroblast growth factor 10
chr4_+_101496648 1.516 ENSMUST00000106930.1
ENSMUST00000154120.1
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr9_-_86695897 1.483 ENSMUST00000034989.8
 Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr13_+_13590402 1.463 ENSMUST00000110559.1
 Lyst
lysosomal trafficking regulator
chr7_+_130865756 1.432 ENSMUST00000120441.1
 Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr7_+_130865835 1.227 ENSMUST00000075181.4
ENSMUST00000048180.5
 Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr1_+_87327008 1.149 ENSMUST00000172794.1
ENSMUST00000164992.2
 Gigyf2

GRB10 interacting GYF protein 2

chr4_+_137862270 1.142 ENSMUST00000130407.1
 Ece1
endothelin converting enzyme 1
chr2_-_54085542 1.116 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr1_-_52817503 1.112 ENSMUST00000162576.1
 Inpp1
inositol polyphosphate-1-phosphatase
chr1_+_87327044 1.029 ENSMUST00000173173.1
 Gigyf2
GRB10 interacting GYF protein 2
chr5_-_135251209 0.953 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)
chr1_+_87326997 0.818 ENSMUST00000027475.8
 Gigyf2
GRB10 interacting GYF protein 2
chr1_-_52817643 0.799 ENSMUST00000027271.2
 Inpp1
inositol polyphosphate-1-phosphatase
chr14_-_63543931 0.659 ENSMUST00000058679.5
 Mtmr9
myotubularin related protein 9
chr11_+_107547925 0.643 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
 Helz


helicase with zinc finger domain


chr2_+_59160884 0.622 ENSMUST00000037903.8
 Pkp4
plakophilin 4
chr7_-_45370559 0.606 ENSMUST00000003971.7
 Lin7b
lin-7 homolog B (C. elegans)
chr12_-_59011996 0.571 ENSMUST00000021375.5
 Sec23a
SEC23A (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 2.7 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 1.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.6 1.7 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.5 1.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 1.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.3 1.5 GO:0072318 clathrin coat disassembly(GO:0072318)
0.4 1.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 1.0 GO:1990523 bone regeneration(GO:1990523)
0.2 1.0 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0031100 organ regeneration(GO:0031100)
0.1 0.4 GO:1901608 regulation of vesicle transport along microtubule(GO:1901608)
0.1 0.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.4 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.0 GO:1990635 proximal dendrite(GO:1990635)
0.0 2.7 GO:0032587 ruffle membrane(GO:0032587)
0.2 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.1 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular_function category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.5 1.9 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.4 1.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.5 1.5 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 1.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.5 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1