ISMARA results: Bhlhe40

Motif ID: Bhlhe40

Z-value: 0.470

Transcription factors associated with Bhlhe40:

Gene Symbol	Entrez ID	Gene Name
Bhlhe40	ENSMUSG00000030103.5	Bhlhe40

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Bhlhe40	mm10_v2_chr6_+_108660772_108660874	0.20	8.0e-02	Click!

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Showing 1 to 20 of 93 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_110095937	4.000	ENSMUST00000106664.3 ENSMUST00000046223.7 ENSMUST00000106662.1	Abca8a	ATP-binding cassette, sub-family A (ABC1), member 8a
chr11_+_97450136	2.823	ENSMUST00000107601.1	Arhgap23	Rho GTPase activating protein 23
chr11_-_110095974	2.592	ENSMUST00000100287.2	Abca8a	ATP-binding cassette, sub-family A (ABC1), member 8a
chr4_-_148038769	2.172	ENSMUST00000030879.5 ENSMUST00000137724.1	Clcn6	chloride channel 6
chr5_+_65199691	2.013	ENSMUST00000041892.8	Wdr19	WD repeat domain 19
chrX_-_136203637	1.922	ENSMUST00000151592.1 ENSMUST00000131510.1 ENSMUST00000066819.4	Tceal5	transcription elongation factor A (SII)-like 5
chr7_+_121707189	1.788	ENSMUST00000065310.2	1700069B07Rik	RIKEN cDNA 1700069B07 gene
chrX_+_136138996	1.665	ENSMUST00000116527.1	Bex4	brain expressed gene 4
chr5_+_123252087	1.503	ENSMUST00000121964.1	Wdr66	WD repeat domain 66
chr3_-_10440054	1.491	ENSMUST00000099223.4 ENSMUST00000029047.6	Snx16	sorting nexin 16
chr1_+_166254095	1.426	ENSMUST00000111416.1	Ildr2	immunoglobulin-like domain containing receptor 2
chr16_-_44139003	1.417	ENSMUST00000124102.1	Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A
chr7_+_35802593	1.330	ENSMUST00000052454.2	E130304I02Rik	RIKEN cDNA E130304I02 gene
chr17_+_70561739	1.315	ENSMUST00000097288.2	Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chrX_+_153832225	1.300	ENSMUST00000148708.1 ENSMUST00000123264.1 ENSMUST00000049999.8	Spin2c	spindlin family, member 2C
chr16_+_8830093	1.238	ENSMUST00000023150.5	1810013L24Rik	RIKEN cDNA 1810013L24 gene
chr5_-_123572976	1.234	ENSMUST00000031388.8	Vps33a	vacuolar protein sorting 33A (yeast)
chr12_+_86947343	1.205	ENSMUST00000038369.4	2310044G17Rik	RIKEN cDNA 2310044G17 gene
chr2_+_166805506	1.171	ENSMUST00000099078.3	Arfgef2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chrX_-_135210672	1.136	ENSMUST00000033783.1	Tceal6	transcription elongation factor A (SII)-like 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 35 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.6	GO:0006869	lipid transport(GO:0006869)
0.1	2.7	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	2.3	GO:0009612	response to mechanical stimulus(GO:0009612)
0.2	2.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.5	2.0	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0	1.9	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.1	1.5	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	1.3	GO:0070842	aggresome assembly(GO:0070842)
0.2	1.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.1	1.2	GO:0048070	regulation of developmental pigmentation(GO:0048070)
0.0	1.2	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3	0.9	GO:0046032	ADP catabolic process(GO:0046032)
0.3	0.9	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0	0.9	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.3	0.8	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
0.3	0.8	GO:0071873	response to norepinephrine(GO:0071873)
0.1	0.8	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.8	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.7	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
0.2	0.6	GO:0002940	tRNA N2-guanine methylation(GO:0002940)

Gene overrepresentation in cellular_component category:

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Showing 1 to 20 of 21 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.4	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.4	3.4	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	2.1	GO:0034399	nuclear periphery(GO:0034399)
0.2	2.0	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	1.8	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	1.5	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.3	1.2	GO:0032280	symmetric synapse(GO:0032280)
0.2	1.2	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	1.0	GO:0033263	CORVET complex(GO:0033263)
0.0	1.0	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1	0.8	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	0.8	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.2	0.6	GO:1990590	ATF1-ATF4 transcription factor complex(GO:1990590)
0.0	0.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.5	GO:0005662	male germ cell nucleus(GO:0001673) DNA replication factor A complex(GO:0005662)
0.0	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.3	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 28 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.6	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1	3.4	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	3.1	GO:0050699	WW domain binding(GO:0050699)
0.1	2.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.2	1.4	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	1.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	1.2	GO:0050811	GABA receptor binding(GO:0050811)
0.3	0.9	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.2	0.9	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.9	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.9	GO:0005246	calcium channel regulator activity(GO:0005246)
0.2	0.8	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.8	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.7	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.2	0.6	GO:0015173	hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1	0.6	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.6	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.6	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.5	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)

Gene overrepresentation in C2:CP category:

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Showing 1 to 7 of 7 entries

Total log-likelihood	Term	Description
1.5	PID_P75_NTR_PATHWAY	p75(NTR)-mediated signaling
1.3	PID_ATR_PATHWAY	ATR signaling pathway
0.9	PID_TCR_CALCIUM_PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.9	PID_EPO_PATHWAY	EPO signaling pathway
0.6	PID_P38_GAMMA_DELTA_PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.6	PID_FRA_PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.5	PID_ECADHERIN_KERATINOCYTE_PATHWAY	E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 13 of 13 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.4	REACTOME_INSULIN_RECEPTOR_RECYCLING	Genes involved in Insulin receptor recycling
0.1	1.8	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA	Genes involved in G beta:gamma signalling through PLC beta
0.2	1.5	REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.5	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	1.2	REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	1.2	REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.8	REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.7	REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.5	REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.4	REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.4	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING	Genes involved in Transferrin endocytosis and recycling