Motif ID: Bptf

Z-value: 2.711


Transcription factors associated with Bptf:

Gene SymbolEntrez IDGene Name
Bptf ENSMUSG00000040481.10 Bptf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bptfmm10_v2_chr11_-_107131922_1071319540.471.3e-05Click!


Activity profile for motif Bptf.

activity profile for motif Bptf


Sorted Z-values histogram for motif Bptf

Sorted Z-values for motif Bptf



Network of associatons between targets according to the STRING database.



First level regulatory network of Bptf

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_116968969 29.540 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr3_+_5218546 24.712 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr16_+_43510267 23.611 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr18_-_62756275 21.947 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr5_-_123012874 21.735 ENSMUST00000172729.1
Kdm2b
lysine (K)-specific demethylase 2B
chr3_+_5218516 21.530 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr1_-_97977233 21.107 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr2_-_118549668 20.943 ENSMUST00000090219.6
Bmf
BCL2 modifying factor
chr17_+_75178797 20.725 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr11_+_44617310 20.558 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr10_-_130280218 20.375 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr3_-_121171678 20.153 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr7_-_37769624 18.664 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr14_-_47411666 17.872 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr5_-_124354671 17.011 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr3_+_5218589 16.790 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr18_-_13972617 16.615 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr16_+_37916440 16.566 ENSMUST00000061274.7
Gpr156
G protein-coupled receptor 156
chr15_-_99820072 16.246 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr19_+_5740885 16.058 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr6_+_134929118 16.034 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr7_-_70360593 15.997 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr14_-_62456286 15.887 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr3_-_86999284 15.841 ENSMUST00000063869.5
ENSMUST00000029717.2
Cd1d1

CD1d1 antigen

chr1_+_20917856 15.672 ENSMUST00000167119.1
Paqr8
progestin and adipoQ receptor family member VIII
chr4_-_53159885 15.250 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr17_+_35077080 15.159 ENSMUST00000172959.1
Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr4_+_144892813 15.083 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr18_-_34751502 14.536 ENSMUST00000060710.7
Cdc25c
cell division cycle 25C
chr4_+_86748526 14.515 ENSMUST00000082026.7
ENSMUST00000045512.8
Dennd4c

DENN/MADD domain containing 4C

chr5_+_92925400 14.395 ENSMUST00000172706.1
Shroom3
shroom family member 3
chr16_+_43508118 14.364 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr5_+_17574268 14.173 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_-_190170671 13.794 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr17_-_35702297 13.725 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr13_-_100786402 13.703 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr6_+_134929089 13.588 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr15_+_102460076 13.486 ENSMUST00000164688.1
Prr13
proline rich 13
chr3_+_86986562 13.358 ENSMUST00000041920.4
Cd1d2
CD1d2 antigen
chr1_+_6734827 13.347 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr17_+_35076902 13.171 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr19_-_7105729 12.664 ENSMUST00000113383.2
Flrt1
fibronectin leucine rich transmembrane protein 1
chr10_+_112271123 12.659 ENSMUST00000092175.2
Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr14_+_70545251 12.575 ENSMUST00000047218.3
Reep4
receptor accessory protein 4
chr2_-_91931774 12.538 ENSMUST00000069423.6
Mdk
midkine
chr12_-_46818749 12.516 ENSMUST00000021438.6
Nova1
neuro-oncological ventral antigen 1
chr17_+_75178911 12.381 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr1_-_77515048 12.065 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr4_-_117182623 11.810 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr16_+_43247278 11.757 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr3_+_127633134 11.132 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr18_-_84086379 11.039 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr4_+_11704439 11.019 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr2_+_152847961 10.773 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr3_-_116968827 10.651 ENSMUST00000119557.1
Palmd
palmdelphin
chr2_-_113848655 10.604 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr17_+_78508063 10.525 ENSMUST00000024880.9
Vit
vitrin
chr14_+_55478753 10.438 ENSMUST00000022821.6
Dhrs4
dehydrogenase/reductase (SDR family) member 4
chr11_-_100822525 10.421 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chr16_+_43364145 10.142 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr7_+_51621830 10.094 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr4_+_144893077 10.069 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr18_+_35829798 10.056 ENSMUST00000060722.6
Cxxc5
CXXC finger 5
chr2_+_152847993 9.997 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr4_+_144893127 9.980 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr8_+_45627709 9.955 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr15_+_102459193 9.924 ENSMUST00000164957.1
ENSMUST00000171245.1
Prr13

proline rich 13

chr18_+_84088077 9.820 ENSMUST00000060223.2
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr13_+_104287855 9.777 ENSMUST00000065766.6
Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr14_-_47418407 9.735 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr13_-_78196373 9.617 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chrX_+_142226765 9.382 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2
chr19_-_28963863 9.216 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr10_-_128176568 8.978 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chrX_-_48513518 8.977 ENSMUST00000114945.2
ENSMUST00000037349.7
Aifm1

apoptosis-inducing factor, mitochondrion-associated 1

chr2_+_119618717 8.891 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr3_+_69004711 8.851 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr4_-_19570073 8.731 ENSMUST00000029885.4
Cpne3
copine III
chr2_-_118547541 8.705 ENSMUST00000110859.2
Bmf
BCL2 modifying factor
chr1_-_44101661 8.595 ENSMUST00000152239.1
Tex30
testis expressed 30
chr7_+_131410601 8.586 ENSMUST00000015829.7
ENSMUST00000117518.1
Acadsb

acyl-Coenzyme A dehydrogenase, short/branched chain

chr2_-_114052804 8.556 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr1_-_119913162 8.525 ENSMUST00000037906.5
Tmem177
transmembrane protein 177
chr3_+_69004969 8.508 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4

structural maintenance of chromosomes 4

chr3_+_156562141 8.355 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr10_-_53630439 8.301 ENSMUST00000075540.5
Mcm9
minichromosome maintenance complex component 9
chr12_-_65172560 8.245 ENSMUST00000052201.8
Mis18bp1
MIS18 binding protein 1
chr5_+_69556924 8.210 ENSMUST00000087228.4
ENSMUST00000031113.6
Guf1

GUF1 GTPase homolog (S. cerevisiae)

chr3_-_51796516 8.170 ENSMUST00000118075.1
Maml3
mastermind like 3 (Drosophila)
chr9_-_124493793 8.124 ENSMUST00000178787.1
Gm21836
predicted gene, 21836
chr19_-_44107447 8.110 ENSMUST00000119591.1
ENSMUST00000026217.4
Chuk

conserved helix-loop-helix ubiquitous kinase

chrX_+_106920618 8.067 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr9_+_72438534 7.995 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr15_-_99875382 7.755 ENSMUST00000073691.3
Lima1
LIM domain and actin binding 1
chr14_+_26579535 7.741 ENSMUST00000037585.7
Dennd6a
DENN/MADD domain containing 6A
chr7_-_46672537 7.715 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr6_+_137754529 7.693 ENSMUST00000087675.6
Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr13_-_78197815 7.592 ENSMUST00000127137.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr18_+_34751803 7.562 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr9_+_15520830 7.558 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr13_+_119462752 7.538 ENSMUST00000026519.8
4833420G17Rik
RIKEN cDNA 4833420G17 gene
chr3_+_116878227 7.507 ENSMUST00000040260.6
Frrs1
ferric-chelate reductase 1
chr19_+_55742242 7.506 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr4_-_117178726 7.491 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr9_+_72438519 7.415 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr5_+_123749696 7.411 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr4_+_32623985 7.398 ENSMUST00000108178.1
Casp8ap2
caspase 8 associated protein 2
chr13_+_112660739 7.391 ENSMUST00000052514.4
Slc38a9
solute carrier family 38, member 9
chr11_-_76399107 7.286 ENSMUST00000021204.3
Nxn
nucleoredoxin
chr10_-_69352886 7.249 ENSMUST00000119827.1
ENSMUST00000020099.5
Cdk1

cyclin-dependent kinase 1

chr7_+_31059342 7.228 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr9_+_83548309 7.101 ENSMUST00000113215.3
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr13_+_51846673 7.082 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr17_-_12909912 7.074 ENSMUST00000163394.1
Pnldc1
poly(A)-specific ribonuclease (PARN)-like domain containing 1
chrX_+_134308084 7.061 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr16_+_43363855 6.932 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chrX_+_101254528 6.929 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr2_-_59948155 6.925 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr4_+_140701466 6.920 ENSMUST00000038893.5
ENSMUST00000138808.1
Rcc2

regulator of chromosome condensation 2

chr3_-_85746266 6.896 ENSMUST00000118408.1
Fam160a1
family with sequence similarity 160, member A1
chr7_-_131410495 6.886 ENSMUST00000121033.1
ENSMUST00000046306.8
Ikzf5

IKAROS family zinc finger 5

chr15_+_102459028 6.820 ENSMUST00000164938.1
ENSMUST00000023810.5
Prr13

proline rich 13

chr13_-_24761440 6.802 ENSMUST00000176890.1
ENSMUST00000175689.1
Gmnn

geminin

chrX_+_166344692 6.792 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr15_-_10713537 6.783 ENSMUST00000090339.3
Rai14
retinoic acid induced 14
chr7_-_133122615 6.660 ENSMUST00000167218.1
Ctbp2
C-terminal binding protein 2
chrX_-_73097017 6.651 ENSMUST00000114524.2
ENSMUST00000074619.5
Xlr3a

X-linked lymphocyte-regulated 3A

chr11_-_34833631 6.613 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr5_-_138155694 6.605 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chr11_+_34314757 6.602 ENSMUST00000165963.1
ENSMUST00000093192.3
Fam196b

family with sequence similarity 196, member B

chr2_-_127133909 6.602 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr7_-_70366735 6.554 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr17_-_71459300 6.540 ENSMUST00000183937.1
Gm4707
predicted gene 4707
chr17_-_70849644 6.506 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr4_-_97584605 6.468 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_-_43426192 6.443 ENSMUST00000101340.4
ENSMUST00000118368.1
ENSMUST00000020685.9
ENSMUST00000020687.8
Pttg1



pituitary tumor-transforming gene 1



chr4_-_97584612 6.442 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr14_+_67745229 6.432 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr9_-_96862903 6.424 ENSMUST00000121077.1
ENSMUST00000124923.1
Acpl2

acid phosphatase-like 2

chr6_+_113531675 6.348 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr3_+_41742615 6.283 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr10_-_61147625 6.242 ENSMUST00000122259.1
Sgpl1
sphingosine phosphate lyase 1
chrX_-_157568983 6.239 ENSMUST00000065806.4
Yy2
Yy2 transcription factor
chr15_-_50889691 6.194 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr9_-_121277160 6.178 ENSMUST00000051479.6
ENSMUST00000171923.1
Ulk4

unc-51-like kinase 4

chr8_+_71951038 6.153 ENSMUST00000131237.1
ENSMUST00000136516.1
ENSMUST00000109997.2
ENSMUST00000132848.1
Zfp961



zinc finger protein 961



chr14_+_120275669 6.088 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr9_+_88839164 6.082 ENSMUST00000163255.2
Trim43c
tripartite motif-containing 43C
chr4_+_136172367 6.042 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr5_+_76656512 6.000 ENSMUST00000086909.4
Gm10430
predicted gene 10430
chr4_-_132732514 5.925 ENSMUST00000045550.4
Xkr8
X Kell blood group precursor related family member 8 homolog
chrX_-_162829379 5.845 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
Txlng


taxilin gamma


chr5_-_111761697 5.833 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr11_-_116027961 5.832 ENSMUST00000106454.1
H3f3b
H3 histone, family 3B
chr11_+_97029925 5.798 ENSMUST00000021249.4
Scrn2
secernin 2
chrX_-_162888426 5.790 ENSMUST00000033723.3
Syap1
synapse associated protein 1
chr8_-_111300222 5.780 ENSMUST00000038739.4
Rfwd3
ring finger and WD repeat domain 3
chr4_-_131838231 5.771 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr17_+_72918298 5.764 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr10_+_41887428 5.749 ENSMUST00000041438.6
Sesn1
sestrin 1
chr12_-_84617326 5.748 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr8_+_84908731 5.732 ENSMUST00000134569.1
Dnase2a
deoxyribonuclease II alpha
chr3_+_156561792 5.693 ENSMUST00000074015.4
Negr1
neuronal growth regulator 1
chr1_+_132298606 5.674 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr16_+_38902305 5.611 ENSMUST00000023478.7
Igsf11
immunoglobulin superfamily, member 11
chr15_-_89171120 5.594 ENSMUST00000109331.1
Plxnb2
plexin B2
chr17_+_35049966 5.575 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr7_-_133123160 5.554 ENSMUST00000166439.1
Ctbp2
C-terminal binding protein 2
chr19_+_55741810 5.552 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr9_+_58134535 5.548 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr1_+_153749496 5.499 ENSMUST00000182722.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr1_-_156032948 5.498 ENSMUST00000136397.1
Tor1aip1
torsin A interacting protein 1
chr6_-_114921778 5.490 ENSMUST00000032459.7
Vgll4
vestigial like 4 (Drosophila)
chr7_+_142460834 5.462 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr2_+_154436437 5.448 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr8_+_84908680 5.435 ENSMUST00000145292.1
Dnase2a
deoxyribonuclease II alpha
chr5_-_88675613 5.383 ENSMUST00000113234.1
ENSMUST00000153565.1
Grsf1

G-rich RNA sequence binding factor 1

chr14_-_24486994 5.341 ENSMUST00000026322.7
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr11_+_95337012 5.325 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr1_+_60181495 5.322 ENSMUST00000160834.1
Nbeal1
neurobeachin like 1
chrX_+_139217166 5.305 ENSMUST00000166444.1
ENSMUST00000170671.1
ENSMUST00000113041.2
ENSMUST00000113042.2
Mum1l1



melanoma associated antigen (mutated) 1-like 1



chrX_+_159532674 5.299 ENSMUST00000057180.6
A830080D01Rik
RIKEN cDNA A830080D01 gene
chr7_+_134670667 5.265 ENSMUST00000084488.4
Dock1
dedicator of cytokinesis 1
chr4_-_45826923 5.248 ENSMUST00000044297.6
Igfbpl1
insulin-like growth factor binding protein-like 1
chr1_-_105659008 5.236 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr2_+_110017879 5.230 ENSMUST00000150183.2
Ccdc34
coiled-coil domain containing 34
chr3_+_135281221 5.209 ENSMUST00000120397.1
ENSMUST00000171974.1
ENSMUST00000029817.7
Bdh2


3-hydroxybutyrate dehydrogenase, type 2


chrX_-_153696195 5.175 ENSMUST00000039424.8
ENSMUST00000112572.1
Kctd12b

potassium channel tetramerisation domain containing 12b

chrX_+_73192222 5.173 ENSMUST00000101486.4
Xlr3b
X-linked lymphocyte-regulated 3B
chr4_-_26346882 5.137 ENSMUST00000041374.7
ENSMUST00000153813.1
Manea

mannosidase, endo-alpha

chr5_+_137745730 5.120 ENSMUST00000100540.3
Tsc22d4
TSC22 domain family, member 4
chr16_-_11909398 5.107 ENSMUST00000127972.1
ENSMUST00000121750.1
ENSMUST00000096272.4
ENSMUST00000073371.6
Cpped1



calcineurin-like phosphoesterase domain containing 1



chr13_+_44731265 5.097 ENSMUST00000173246.1
Jarid2
jumonji, AT rich interactive domain 2
chr3_+_76074270 5.084 ENSMUST00000038364.8
Fstl5
follistatin-like 5
chr17_-_40935047 5.037 ENSMUST00000087114.3
Cenpq
centromere protein Q
chr4_-_132422394 5.031 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr9_+_107576915 5.025 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr15_-_89170688 5.009 ENSMUST00000060808.9
Plxnb2
plexin B2
chrX_-_73265390 4.996 ENSMUST00000080839.1
Xlr3c
X-linked lymphocyte-regulated 3C
chr15_+_102296256 4.965 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 36.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
6.7 20.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
5.4 16.1 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
5.3 15.8 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
5.2 15.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
4.6 13.7 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
4.3 8.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
4.2 12.5 GO:0030421 defecation(GO:0030421)
4.1 4.1 GO:0072284 metanephric S-shaped body morphogenesis(GO:0072284)
4.0 12.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
3.9 19.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
3.8 19.1 GO:0021993 initiation of neural tube closure(GO:0021993)
3.8 15.2 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
3.8 60.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.7 11.0 GO:0060023 soft palate development(GO:0060023)
3.5 10.4 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
3.4 30.3 GO:0048102 autophagic cell death(GO:0048102)
3.3 9.9 GO:0061386 closure of optic fissure(GO:0061386)
3.2 6.4 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
3.0 24.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.7 8.1 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
2.4 14.2 GO:0003350 pulmonary myocardium development(GO:0003350)
2.2 4.4 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
2.2 8.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
2.1 17.1 GO:0048625 myoblast fate commitment(GO:0048625)
2.0 5.9 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
2.0 5.9 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.9 7.7 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.9 7.7 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
1.9 7.7 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
1.9 5.6 GO:0006592 ornithine biosynthetic process(GO:0006592)
1.8 5.3 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
1.8 72.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.8 21.1 GO:0009404 toxin metabolic process(GO:0009404)
1.7 24.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
1.7 15.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.7 5.0 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.7 8.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.6 1.6 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.6 14.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
1.6 20.4 GO:0035881 amacrine cell differentiation(GO:0035881)
1.5 4.6 GO:1903519 negative regulation of interleukin-1 beta secretion(GO:0050713) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.5 9.0 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.5 10.4 GO:0042574 retinal metabolic process(GO:0042574)
1.5 5.9 GO:0034239 regulation of macrophage fusion(GO:0034239)
1.5 5.8 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
1.4 4.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.4 5.8 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
1.4 4.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
1.4 4.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.4 6.9 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
1.4 33.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
1.3 4.0 GO:1905065 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
1.3 16.0 GO:0070986 left/right axis specification(GO:0070986)
1.3 3.8 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
1.3 3.8 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.3 3.8 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.2 3.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
1.2 7.4 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
1.2 7.4 GO:0036337 Fas signaling pathway(GO:0036337)
1.2 4.9 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
1.2 10.8 GO:0071763 nuclear membrane organization(GO:0071763)
1.2 2.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
1.2 2.4 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
1.2 1.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.2 7.1 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
1.2 3.5 GO:0006642 triglyceride mobilization(GO:0006642) oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
1.2 12.9 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.1 5.7 GO:0009235 cobalamin metabolic process(GO:0009235)
1.1 2.3 GO:0090235 regulation of metaphase plate congression(GO:0090235)
1.1 3.4 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.1 10.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
1.1 8.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.1 5.5 GO:0061205 paramesonephric duct development(GO:0061205)
1.1 3.3 GO:0050915 sensory perception of sour taste(GO:0050915)
1.1 16.5 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
1.1 4.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
1.1 14.1 GO:0071732 cellular response to nitric oxide(GO:0071732)
1.1 3.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.1 17.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.1 6.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
1.0 4.2 GO:1990414 negative regulation of mitotic recombination(GO:0045950) replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
1.0 2.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.0 5.2 GO:0061038 uterus morphogenesis(GO:0061038)
1.0 12.3 GO:0034501 protein localization to kinetochore(GO:0034501)
1.0 6.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.0 10.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
1.0 3.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.0 2.9 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.0 9.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.9 5.7 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.9 28.3 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.9 30.7 GO:0060325 face morphogenesis(GO:0060325)
0.9 3.6 GO:0014012 negative regulation of Schwann cell proliferation(GO:0010626) peripheral nervous system axon regeneration(GO:0014012)
0.9 6.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.9 2.7 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.9 0.9 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.9 1.8 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.9 3.5 GO:0030091 protein repair(GO:0030091)
0.9 6.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.9 6.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.9 2.6 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.9 13.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.8 4.2 GO:0061511 centriole elongation(GO:0061511)
0.8 5.0 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.8 5.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.8 3.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.8 4.9 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.8 4.0 GO:0030183 B cell differentiation(GO:0030183)
0.8 6.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.8 2.4 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.8 3.1 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.8 2.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.8 3.1 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.8 1.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.8 4.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.8 5.3 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.8 7.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.7 4.4 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.7 14.5 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.7 6.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.7 2.1 GO:0036509 trimming of terminal mannose on B branch(GO:0036509)
0.7 3.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.7 4.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.7 2.8 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.7 3.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.7 18.7 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.7 3.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.7 2.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.7 9.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.7 10.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.6 4.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.6 18.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.6 3.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.6 2.5 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.6 1.9 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.6 3.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.6 3.0 GO:2000482 interleukin-8 secretion(GO:0072606) regulation of interleukin-8 secretion(GO:2000482)
0.6 3.0 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.6 3.0 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.6 16.1 GO:0051310 metaphase plate congression(GO:0051310)
0.6 3.5 GO:0051095 regulation of helicase activity(GO:0051095)
0.6 1.7 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.6 0.6 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.6 5.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.6 1.1 GO:0006401 RNA catabolic process(GO:0006401)
0.6 2.3 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.5 5.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.5 0.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.5 2.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.5 1.6 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.5 2.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.5 1.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 16.5 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.5 3.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.5 1.6 GO:0003334 keratinocyte development(GO:0003334)
0.5 2.6 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.5 3.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.5 2.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 1.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.5 5.0 GO:0051307 meiotic chromosome separation(GO:0051307)
0.5 1.5 GO:0021546 rhombomere development(GO:0021546)
0.5 2.0 GO:0061156 pulmonary artery morphogenesis(GO:0061156)
0.5 3.4 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.5 3.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.5 1.4 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of reciprocal meiotic recombination(GO:0010845)
0.5 1.4 GO:0015793 glycerol transport(GO:0015793)
0.5 25.0 GO:0031529 ruffle organization(GO:0031529)
0.5 2.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.4 4.0 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.4 3.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.4 6.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.4 0.9 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.4 1.7 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.4 0.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 8.0 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.4 12.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 4.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.4 1.2 GO:1905077 T-helper 17 cell lineage commitment(GO:0072540) negative regulation of interleukin-17 secretion(GO:1905077)
0.4 7.1 GO:0034508 centromere complex assembly(GO:0034508)
0.4 4.5 GO:0033572 transferrin transport(GO:0033572)
0.4 17.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.4 3.7 GO:0060973 cell migration involved in heart development(GO:0060973)
0.4 2.9 GO:0071372 cellular response to gonadotropin stimulus(GO:0071371) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.4 1.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.4 2.4 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.4 2.4 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.4 1.6 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.4 1.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 1.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.4 3.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4 2.4 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.4 0.4 GO:0051593 response to folic acid(GO:0051593)
0.4 1.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.4 8.1 GO:0051482 positive regulation of Rho protein signal transduction(GO:0035025) positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.4 1.1 GO:0035690 cellular response to drug(GO:0035690)
0.4 4.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 2.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.4 1.5 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.4 3.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.4 4.4 GO:0060349 bone morphogenesis(GO:0060349)
0.4 4.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.4 2.9 GO:0050957 equilibrioception(GO:0050957)
0.4 6.6 GO:0015693 magnesium ion transport(GO:0015693)
0.4 1.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.4 2.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.4 3.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.4 0.4 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.4 1.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.4 1.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.4 7.8 GO:0001967 suckling behavior(GO:0001967)
0.3 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.3 1.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 5.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.3 1.7 GO:0033762 response to glucagon(GO:0033762)
0.3 1.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 3.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.3 3.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.3 6.9 GO:0060009 Sertoli cell development(GO:0060009)
0.3 2.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 6.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.3 5.2 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.3 2.9 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.3 3.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 1.6 GO:0019614 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.3 2.6 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.3 8.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.3 1.6 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.3 2.5 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.3 3.8 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.3 1.5 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.3 7.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3 0.9 GO:0090399 replicative senescence(GO:0090399)
0.3 1.2 GO:0021764 amygdala development(GO:0021764)
0.3 0.9 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.3 3.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.3 2.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 0.9 GO:0046061 dATP catabolic process(GO:0046061)
0.3 0.8 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.3 9.9 GO:0006270 DNA replication initiation(GO:0006270)
0.3 4.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 1.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.3 5.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 0.8 GO:0042732 D-xylose metabolic process(GO:0042732)
0.3 1.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 1.3 GO:0035878 nail development(GO:0035878)
0.3 2.8 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.3 45.6 GO:0008360 regulation of cell shape(GO:0008360)
0.3 8.0 GO:0030488 tRNA methylation(GO:0030488)
0.2 1.5 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 3.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.2 1.7 GO:0070475 rRNA base methylation(GO:0070475)
0.2 5.9 GO:0033687 osteoblast proliferation(GO:0033687)
0.2 4.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 1.9 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.2 1.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 2.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.2 0.9 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 1.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 4.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 3.7 GO:0030033 microvillus assembly(GO:0030033)
0.2 3.7 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 3.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 4.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.2 2.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.0 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.2 1.7 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 0.4 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 0.6 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.2 1.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2 5.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.2 1.8 GO:0006379 mRNA cleavage(GO:0006379)
0.2 0.6 GO:0060021 palate development(GO:0060021)
0.2 0.8 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.2 1.2 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2 1.9 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.1 GO:0043144 snoRNA processing(GO:0043144)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 1.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.2 2.9 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.2 1.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 0.9 GO:0006817 phosphate ion transport(GO:0006817)
0.2 1.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 2.9 GO:0034204 lipid translocation(GO:0034204)
0.2 6.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.2 1.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.4 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.2 3.3 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.2 0.9 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 2.7 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.2 2.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.2 1.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 7.4 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.2 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 1.7 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.2 2.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 1.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 1.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 1.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 3.7 GO:0000578 embryonic axis specification(GO:0000578)
0.2 1.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 5.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620) folic acid transport(GO:0015884)
0.1 1.5 GO:0015838 amino-acid betaine transport(GO:0015838)
0.1 1.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.9 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 5.7 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 2.4 GO:0034340 response to type I interferon(GO:0034340)
0.1 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 2.2 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597) learned vocalization behavior or vocal learning(GO:0098598)
0.1 3.6 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.8 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.8 GO:0031297 replication fork processing(GO:0031297)
0.1 1.8 GO:0042711 maternal behavior(GO:0042711)
0.1 3.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 2.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 5.3 GO:0048477 oogenesis(GO:0048477)
0.1 0.4 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 1.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 1.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 1.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.8 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.2 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 14.1 GO:0050684 regulation of mRNA processing(GO:0050684)
0.1 6.6 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.5 GO:0043248 proteasome assembly(GO:0043248)
0.1 6.0 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 1.3 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 1.5 GO:0010453 regulation of cell fate commitment(GO:0010453)
0.1 1.7 GO:0042407 cristae formation(GO:0042407)
0.1 1.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.6 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 1.3 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 1.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 2.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 11.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 1.6 GO:0070875 positive regulation of glycogen metabolic process(GO:0070875)
0.1 2.0 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 1.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 4.0 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.5 GO:0015819 lysine transport(GO:0015819) ornithine transport(GO:0015822)
0.1 1.9 GO:0065004 nucleosome assembly(GO:0006334) chromatin assembly(GO:0031497) protein-DNA complex assembly(GO:0065004)
0.1 0.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 1.9 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 0.4 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1 0.9 GO:0051923 sulfation(GO:0051923)
0.1 2.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.3 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 5.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.4 GO:0070627 ferrous iron import(GO:0070627)
0.1 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 1.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 2.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.0 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 1.9 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 4.1 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.1 1.2 GO:0044458 motile cilium assembly(GO:0044458)
0.1 8.9 GO:1990138 neuron projection extension(GO:1990138)
0.1 1.1 GO:0051642 centrosome localization(GO:0051642)
0.1 1.0 GO:0030307 positive regulation of cell growth(GO:0030307)
0.1 0.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 1.9 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 1.7 GO:0035329 hippo signaling(GO:0035329)
0.1 6.6 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.6 GO:0006298 mismatch repair(GO:0006298)
0.1 0.6 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 3.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 2.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.6 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 1.0 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.7 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.7 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.1 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.9 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.6 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.3 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 2.1 GO:0051028 mRNA transport(GO:0051028)
0.0 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 1.9 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.4 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.0 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.0 GO:0098706 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.3 GO:0043488 regulation of mRNA stability(GO:0043488)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 33.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
3.4 13.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
2.8 8.5 GO:1990047 spindle matrix(GO:1990047)
2.6 20.8 GO:0005818 aster(GO:0005818)
2.5 7.4 GO:1990423 RZZ complex(GO:1990423)
2.4 24.0 GO:0000796 condensin complex(GO:0000796)
1.9 17.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
1.5 27.6 GO:0031616 spindle pole centrosome(GO:0031616)
1.2 1.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
1.2 7.4 GO:0071986 Ragulator complex(GO:0071986)
1.2 3.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.1 21.0 GO:0000800 lateral element(GO:0000800)
1.0 9.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.9 6.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.9 4.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.9 8.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.9 4.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.9 14.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.8 10.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.8 15.6 GO:0097470 ribbon synapse(GO:0097470)
0.8 4.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.8 6.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.8 14.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.8 11.7 GO:0042555 MCM complex(GO:0042555)
0.8 2.3 GO:0097447 dendritic tree(GO:0097447)
0.8 3.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.8 1.6 GO:0005899 insulin receptor complex(GO:0005899)
0.8 4.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.7 2.6 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.6 25.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.6 3.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.6 6.9 GO:0034464 BBSome(GO:0034464)
0.6 19.6 GO:0035371 microtubule plus-end(GO:0035371)
0.6 1.8 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.6 2.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.6 11.0 GO:0051233 spindle midzone(GO:0051233)
0.6 4.5 GO:0031415 NatA complex(GO:0031415)
0.6 5.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 13.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 1.6 GO:0031251 PAN complex(GO:0031251)
0.5 6.3 GO:0061700 GATOR2 complex(GO:0061700)
0.5 2.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.5 2.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.5 12.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.5 30.2 GO:0016459 myosin complex(GO:0016459)
0.5 7.9 GO:0036038 MKS complex(GO:0036038)
0.5 2.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.5 3.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.4 5.7 GO:0005614 interstitial matrix(GO:0005614)
0.4 1.7 GO:0031983 vesicle lumen(GO:0031983)
0.4 21.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 5.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 10.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 19.0 GO:0031519 PcG protein complex(GO:0031519)
0.4 2.7 GO:0033503 HULC complex(GO:0033503)
0.4 3.1 GO:0042382 paraspeckles(GO:0042382)
0.4 1.9 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 5.3 GO:0031011 Ino80 complex(GO:0031011)
0.4 14.7 GO:0005876 spindle microtubule(GO:0005876)
0.4 3.7 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.4 16.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 7.4 GO:0005605 basal lamina(GO:0005605)
0.3 2.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.3 3.0 GO:0061617 MICOS complex(GO:0061617)
0.3 4.4 GO:0031045 dense core granule(GO:0031045)
0.3 9.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 3.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 1.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 18.7 GO:0030667 secretory granule membrane(GO:0030667)
0.3 3.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 2.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 1.4 GO:0032797 SMN complex(GO:0032797)
0.3 1.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 5.2 GO:0035869 ciliary transition zone(GO:0035869)
0.3 4.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 3.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.3 1.0 GO:0001652 granular component(GO:0001652)
0.3 4.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 3.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 3.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 7.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 3.1 GO:0033268 node of Ranvier(GO:0033268)
0.2 1.4 GO:0035976 AP1 complex(GO:0035976)
0.2 1.6 GO:0000346 transcription export complex(GO:0000346)
0.2 12.1 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.1 GO:0005667 transcription factor complex(GO:0005667)
0.2 2.3 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 5.7 GO:0035861 site of double-strand break(GO:0035861)
0.2 5.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 32.7 GO:0000775 chromosome, centromeric region(GO:0000775)
0.2 0.6 GO:0030286 dynein complex(GO:0030286)
0.2 1.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 8.4 GO:1990391 DNA repair complex(GO:1990391)
0.2 27.2 GO:0043296 apical junction complex(GO:0043296)
0.2 2.8 GO:0000242 pericentriolar material(GO:0000242)
0.2 6.7 GO:0034707 chloride channel complex(GO:0034707)
0.2 1.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 6.8 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.2 GO:0097542 ciliary tip(GO:0097542)
0.2 2.1 GO:0005902 microvillus(GO:0005902)
0.1 3.0 GO:0005771 multivesicular body(GO:0005771)
0.1 1.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.9 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.6 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 2.0 GO:0005922 connexon complex(GO:0005922)
0.1 0.6 GO:0035859 Seh1-associated complex(GO:0035859)
0.1 12.2 GO:0036126 sperm flagellum(GO:0036126)
0.1 5.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 26.3 GO:0043197 dendritic spine(GO:0043197)
0.1 1.1 GO:0070852 cell body fiber(GO:0070852)
0.1 2.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.3 GO:0097546 ciliary base(GO:0097546)
0.1 0.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 4.2 GO:0000922 spindle pole(GO:0000922)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.4 GO:0001741 XY body(GO:0001741)
0.1 1.0 GO:0036157 outer dynein arm(GO:0036157)
0.1 2.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 3.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 11.7 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.1 11.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.6 GO:0070847 core mediator complex(GO:0070847)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 3.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 11.5 GO:0043235 receptor complex(GO:0043235)
0.1 8.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 1.4 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.5 GO:0005844 polysome(GO:0005844)
0.1 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.9 GO:0045178 basal part of cell(GO:0045178)
0.1 2.2 GO:0016235 aggresome(GO:0016235)
0.1 3.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 8.5 GO:0005925 focal adhesion(GO:0005925)
0.1 1.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.7 GO:0005811 lipid particle(GO:0005811)
0.0 3.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.1 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.6 GO:0000502 proteasome complex(GO:0000502)
0.0 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 7.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 201.9 GO:0005634 nucleus(GO:0005634)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.0 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 28.3 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
8.3 33.1 GO:0050436 microfibril binding(GO:0050436)
7.0 21.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
5.3 15.8 GO:0071723 lipopeptide binding(GO:0071723)
5.1 15.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
5.1 15.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
5.0 35.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
3.8 22.6 GO:0001972 retinoic acid binding(GO:0001972)
3.6 10.7 GO:0008384 IkappaB kinase activity(GO:0008384)
3.5 10.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
3.4 13.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
3.3 9.8 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
3.0 9.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
2.8 16.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
2.6 23.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
2.6 7.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
2.1 32.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
2.1 12.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
2.0 9.9 GO:0072542 protein phosphatase activator activity(GO:0072542)
1.9 15.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.9 5.6 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
1.8 11.1 GO:0070728 leucine binding(GO:0070728)
1.7 5.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.7 13.8 GO:0050693 LBD domain binding(GO:0050693)
1.7 6.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.7 5.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.5 13.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.5 4.5 GO:0004998 transferrin receptor activity(GO:0004998)
1.5 7.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.5 20.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.5 7.3 GO:0047134 thioredoxin-disulfide reductase activity(GO:0004791) protein-disulfide reductase activity(GO:0047134)
1.4 18.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
1.4 5.6 GO:0004528 phosphodiesterase I activity(GO:0004528)
1.3 6.6 GO:0043515 kinetochore binding(GO:0043515)
1.3 5.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.3 3.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.2 3.5 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
1.2 8.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
1.1 18.1 GO:0051010 microtubule plus-end binding(GO:0051010)
1.1 21.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.1 3.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.1 3.3 GO:0008527 taste receptor activity(GO:0008527)
1.1 6.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.1 14.2 GO:0038191 neuropilin binding(GO:0038191)
1.1 5.3 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
1.1 7.4 GO:0032184 SUMO polymer binding(GO:0032184)
1.0 16.4 GO:0045295 gamma-catenin binding(GO:0045295)
1.0 2.9 GO:0036033 mediator complex binding(GO:0036033)
0.9 2.8 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.9 3.7 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.9 4.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.9 9.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.9 4.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.9 3.5 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.9 2.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.9 6.9 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.8 4.2 GO:0000405 bubble DNA binding(GO:0000405)
0.8 23.4 GO:0003785 actin monomer binding(GO:0003785)
0.8 3.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.8 7.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.8 10.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.7 22.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 7.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.7 2.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7 4.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.7 6.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.7 3.5 GO:0016778 diphosphotransferase activity(GO:0016778)
0.7 3.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.7 6.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.7 14.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.6 3.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.6 1.9 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.6 3.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.6 3.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.6 28.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6 3.7 GO:0097001 ceramide binding(GO:0097001)
0.6 3.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6 2.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 1.8 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.6 2.4 GO:0008142 oxysterol binding(GO:0008142)
0.6 3.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.6 1.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.6 3.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.6 1.7 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.6 3.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 2.3 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.6 8.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.6 4.5 GO:0016421 CoA carboxylase activity(GO:0016421)
0.6 2.2 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.5 1.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.5 1.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.5 1.6 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.5 4.2 GO:0043559 insulin binding(GO:0043559)
0.5 9.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 7.2 GO:0035173 histone kinase activity(GO:0035173)
0.5 2.1 GO:0051378 serotonin binding(GO:0051378)
0.5 9.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.5 11.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 4.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.5 2.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5 1.9 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.5 1.9 GO:0097108 hedgehog family protein binding(GO:0097108)
0.5 3.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.5 4.1 GO:0070513 death domain binding(GO:0070513)
0.5 2.3 GO:0045545 syndecan binding(GO:0045545)
0.4 7.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 3.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.4 3.0 GO:0001849 complement component C1q binding(GO:0001849)
0.4 1.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.4 6.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 5.0 GO:0050897 cobalt ion binding(GO:0050897)
0.4 6.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 3.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 1.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.4 0.8 GO:0004532 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016796) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.4 1.2 GO:0051870 methotrexate binding(GO:0051870)
0.4 70.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 2.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 2.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4 5.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.4 2.6 GO:0031419 cobalamin binding(GO:0031419)
0.4 5.5 GO:0016805 dipeptidase activity(GO:0016805)
0.4 1.4 GO:0004103 choline kinase activity(GO:0004103)
0.4 12.6 GO:0050699 WW domain binding(GO:0050699)
0.3 3.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3 3.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 2.4 GO:0015925 galactosidase activity(GO:0015925)
0.3 2.0 GO:0016803 ether hydrolase activity(GO:0016803)
0.3 7.6 GO:0005521 lamin binding(GO:0005521)
0.3 8.1 GO:0032452 histone demethylase activity(GO:0032452)
0.3 10.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 1.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 5.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.3 13.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3 1.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.3 10.5 GO:0004386 helicase activity(GO:0004386)
0.3 1.6 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3 7.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 15.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.3 2.8 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 1.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 4.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 1.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3 1.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 5.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 0.9 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 3.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 9.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 0.9 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673) sphingolipid transporter activity(GO:0046624)
0.3 0.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 2.9 GO:0005167 neurotrophin TRK receptor binding(GO:0005167) chemorepellent activity(GO:0045499)
0.3 10.1 GO:0070888 E-box binding(GO:0070888)
0.3 8.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 1.6 GO:0034046 poly(G) binding(GO:0034046)
0.3 4.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 4.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 4.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 2.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 3.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 1.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 1.9 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3 1.6 GO:0050733 RS domain binding(GO:0050733)
0.3 1.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 1.5 GO:0000150 recombinase activity(GO:0000150)
0.2 1.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 0.9 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 1.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 1.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 0.9 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 40.6 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.2 1.3 GO:1990405 protein antigen binding(GO:1990405)
0.2 2.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.2 1.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 2.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 0.4 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.2 4.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.2 3.7 GO:0004697 protein kinase C activity(GO:0004697)
0.2 8.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 1.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 7.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.2 6.7 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.2 0.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 3.8 GO:0008143 poly(A) binding(GO:0008143)
0.2 1.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.2 7.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 2.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 2.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 2.1 GO:0005522 profilin binding(GO:0005522)
0.2 1.2 GO:0016801 hydrolase activity, acting on ether bonds(GO:0016801)
0.2 0.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 8.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 1.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 26.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2 2.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.2 0.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 1.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 1.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 10.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.1 8.4 GO:0019003 GDP binding(GO:0019003)
0.1 3.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 2.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 7.1 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.1 GO:0043495 protein anchor(GO:0043495)
0.1 0.9 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.1 5.0 GO:0017022 myosin binding(GO:0017022)
0.1 0.5 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.1 7.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 64.9 GO:0008270 zinc ion binding(GO:0008270)
0.1 0.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 5.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 2.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 2.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.9 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 3.7 GO:0030552 cAMP binding(GO:0030552)
0.1 3.0 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 3.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 6.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.3 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.1 5.9 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 6.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 1.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 1.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 2.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 10.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 3.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.7 GO:0005112 Notch binding(GO:0005112)
0.1 7.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 5.5 GO:0004519 endonuclease activity(GO:0004519)
0.1 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.6 GO:0043022 ribosome binding(GO:0043022)
0.0 1.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 2.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.3 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.7 GO:0030594 neurotransmitter receptor activity(GO:0030594)
0.0 0.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
2.0 4.0 PID_FAS_PATHWAY FAS (CD95) signaling pathway
1.5 13.5 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
1.1 48.4 PID_AURORA_A_PATHWAY Aurora A signaling
1.1 8.7 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.0 41.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.9 42.2 PID_PLK1_PATHWAY PLK1 signaling events
0.7 39.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.6 8.1 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6 11.8 PID_IL5_PATHWAY IL5-mediated signaling events
0.5 5.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.5 13.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.5 8.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.4 61.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.4 12.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.4 14.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.4 21.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.4 2.4 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.4 30.8 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.4 16.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.4 8.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.4 7.9 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 7.9 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.3 10.2 PID_ATM_PATHWAY ATM pathway
0.3 5.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 11.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 7.1 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.3 21.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.3 9.1 PID_IGF1_PATHWAY IGF1 pathway
0.3 6.8 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.3 6.6 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.3 3.8 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 3.3 PID_IL27_PATHWAY IL27-mediated signaling events
0.2 0.9 PID_IL23_PATHWAY IL23-mediated signaling events
0.2 4.2 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 2.6 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 1.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 1.6 PID_INSULIN_PATHWAY Insulin Pathway
0.2 4.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 6.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.2 2.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 2.1 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 2.8 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 6.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 4.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 14.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 7.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 0.2 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 3.5 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 8.0 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 1.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 6.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 6.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.7 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.3 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 2.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 6.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.7 PID_P73PATHWAY p73 transcription factor network
0.0 0.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 34.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.1 6.4 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
1.6 6.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.2 15.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
1.1 28.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
1.0 11.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
1.0 10.7 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.0 16.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.9 10.4 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.9 8.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.8 11.3 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.7 7.0 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.7 2.1 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.7 7.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.6 63.9 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.6 2.8 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.5 42.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.5 2.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.4 9.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 18.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 1.3 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.4 11.2 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.4 3.1 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.4 8.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.4 11.2 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.3 1.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 3.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 4.0 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 2.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.3 5.5 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.3 12.1 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 4.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 3.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.3 6.2 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.3 6.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 3.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 2.7 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 4.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.2 2.0 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 9.0 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 2.6 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.2 6.6 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.2 2.1 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 3.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 1.3 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 7.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 6.5 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 1.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.2 0.9 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 1.9 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 7.0 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.2 2.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 3.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.1 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 8.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.2 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.3 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.1 3.1 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 3.5 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 1.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 4.0 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 0.8 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.6 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 2.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 3.5 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.5 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 2.3 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.9 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.2 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 1.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 3.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 0.2 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 2.0 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.8 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.2 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins