Motif ID: Bsx
Z-value: 0.450
Transcription factors associated with Bsx:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bsx | ENSMUSG00000054360.3 | Bsx |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Bsx | mm10_v2_chr9_+_40873981_40874127 | -0.06 | 5.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 14.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 1.3 | 9.3 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.9 | 2.8 | GO:1904207 | chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 0.5 | 3.0 | GO:0002317 | plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598) |
| 0.5 | 1.4 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 0.4 | 1.3 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.4 | 2.1 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
| 0.3 | 4.6 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.3 | 0.8 | GO:2000097 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.2 | 2.4 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.2 | 1.7 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.2 | 0.4 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 0.2 | 1.1 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) |
| 0.2 | 1.0 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.2 | 2.3 | GO:0048199 | protein localization to pre-autophagosomal structure(GO:0034497) vesicle targeting, to, from or within Golgi(GO:0048199) |
| 0.1 | 4.2 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.1 | 0.8 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.1 | 2.5 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 0.6 | GO:0051661 | maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684) |
| 0.1 | 1.1 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.1 | 1.4 | GO:0032570 | response to progesterone(GO:0032570) |
| 0.1 | 0.4 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.1 | 1.3 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.1 | 0.5 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.1 | 1.0 | GO:0044144 | regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144) |
| 0.1 | 0.3 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.1 | 0.8 | GO:1904861 | excitatory synapse assembly(GO:1904861) |
| 0.0 | 1.3 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
| 0.0 | 0.6 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.0 | 1.0 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 0.5 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.0 | 0.5 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.7 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 0.1 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.0 | 1.8 | GO:0016052 | carbohydrate catabolic process(GO:0016052) |
| 0.0 | 0.5 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.4 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.6 | GO:0009311 | oligosaccharide metabolic process(GO:0009311) |
| 0.0 | 0.4 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.1 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.2 | 1.4 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.2 | 1.5 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 2.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.2 | 0.8 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.1 | 0.4 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.1 | 0.7 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 24.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 1.1 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 3.3 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 4.2 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.1 | GO:0034657 | GID complex(GO:0034657) |
| 0.0 | 0.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 1.0 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 1.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 1.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.7 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 1.3 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.8 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
| 0.0 | 2.5 | GO:0030141 | secretory granule(GO:0030141) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 14.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.8 | 9.3 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.6 | 3.0 | GO:0005534 | galactose binding(GO:0005534) |
| 0.6 | 1.8 | GO:0016160 | alpha-amylase activity(GO:0004556) amylase activity(GO:0016160) |
| 0.6 | 2.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.3 | 2.1 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.3 | 1.1 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.2 | 1.0 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 0.4 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 0.1 | 1.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 0.4 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 0.1 | 1.1 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 2.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.4 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.1 | 0.5 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 1.0 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 1.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.2 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.8 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.0 | 1.4 | GO:0004601 | peroxidase activity(GO:0004601) |
| 0.0 | 1.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 2.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 1.3 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) thiolester hydrolase activity(GO:0016790) |
| 0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 2.8 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 2.0 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.8 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.6 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.0 | 0.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.6 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 1.3 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
| 0.0 | 0.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.5 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.2 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.0 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 2.4 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.8 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 2.8 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.5 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 13.7 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.2 | 9.3 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 2.4 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.3 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 1.4 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 2.8 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 4.2 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.4 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.7 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.1 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 1.0 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.8 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
