Motif ID: Cdc5l

Z-value: 0.747


Transcription factors associated with Cdc5l:

Gene SymbolEntrez IDGene Name
Cdc5l ENSMUSG00000023932.8 Cdc5l

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cdc5lmm10_v2_chr17_-_45433682_454337090.281.2e-02Click!


Activity profile for motif Cdc5l.

activity profile for motif Cdc5l


Sorted Z-values histogram for motif Cdc5l

Sorted Z-values for motif Cdc5l



Network of associatons between targets according to the STRING database.



First level regulatory network of Cdc5l

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_31447383 9.968 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr9_-_112187766 9.722 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr2_+_65620829 9.165 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr9_-_112187898 8.913 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_66968559 7.660 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr5_+_66968416 7.567 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr12_+_29528382 5.691 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr5_+_107497762 5.547 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr12_+_74297474 5.272 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr2_-_64975762 5.056 ENSMUST00000156765.1
 Grb14
growth factor receptor bound protein 14
chr1_+_143640664 4.822 ENSMUST00000038252.2
 B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr4_-_149126688 4.822 ENSMUST00000030815.2
 Cort
cortistatin
chr5_+_107497718 4.789 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr19_+_26749726 4.313 ENSMUST00000175842.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_55919605 3.739 ENSMUST00000037408.8
 Scaper
S phase cyclin A-associated protein in the ER
chr15_-_13173607 3.598 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr4_+_95967205 2.478 ENSMUST00000030306.7
 Hook1
hook homolog 1 (Drosophila)
chr17_-_78684262 2.466 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chrX_-_37104523 2.262 ENSMUST00000130324.1
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr1_-_30863256 2.138 ENSMUST00000088310.3
 Phf3
PHD finger protein 3
chr3_-_49757257 2.024 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr9_-_96752822 1.976 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr1_+_180111339 1.928 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr18_-_22850738 1.842 ENSMUST00000092015.4
ENSMUST00000069215.6
 Nol4

nucleolar protein 4

chrX_+_136822781 1.722 ENSMUST00000113085.1
 Plp1
proteolipid protein (myelin) 1
chrX_+_136822671 1.549 ENSMUST00000033800.6
 Plp1
proteolipid protein (myelin) 1
chr5_-_31220491 0.871 ENSMUST00000031032.7
 Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr7_+_130577334 0.671 ENSMUST00000059145.7
ENSMUST00000084513.4
 Tacc2

transforming, acidic coiled-coil containing protein 2

chr6_+_88724828 0.545 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr4_-_119383732 0.474 ENSMUST00000044781.2
ENSMUST00000084307.3
 Ccdc30

coiled-coil domain containing 30

chr1_+_17601893 0.344 ENSMUST00000088476.2
 Pi15
peptidase inhibitor 15
chr19_-_5797410 0.329 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr2_-_72986716 0.157 ENSMUST00000112062.1
 Gm11084
predicted gene 11084
chr2_+_106695594 0.111 ENSMUST00000016530.7
 Mpped2
metallophosphoesterase domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
1.2 10.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.5 4.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5 4.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.4 18.6 GO:0034605 cellular response to heat(GO:0034605)
0.3 4.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 3.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 5.7 GO:0048665 neuron fate specification(GO:0048665)
0.1 2.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 17.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 2.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 2.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 3.6 GO:0007219 Notch signaling pathway(GO:0007219)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.0 GO:0097449 astrocyte projection(GO:0097449)
0.4 2.5 GO:0070695 FHF complex(GO:0070695)
0.2 4.3 GO:0071564 npBAF complex(GO:0071564)
0.1 2.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 2.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.9 GO:0042641 actomyosin(GO:0042641)
0.0 3.3 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.0 GO:0030348 syntaxin-3 binding(GO:0030348)
1.2 4.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 5.7 GO:0050897 cobalt ion binding(GO:0050897)
0.4 3.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 4.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 5.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 2.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 18.6 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 15.2 GO:0003779 actin binding(GO:0003779)
0.0 4.3 GO:0004386 helicase activity(GO:0004386)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.5 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.1 4.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.9 PID_CDC42_PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 2.3 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis