Motif ID: Cpeb1

Z-value: 2.061


Transcription factors associated with Cpeb1:

Gene SymbolEntrez IDGene Name
Cpeb1 ENSMUSG00000025586.10 Cpeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cpeb1mm10_v2_chr7_-_81454751_814547640.019.0e-01Click!


Activity profile for motif Cpeb1.

activity profile for motif Cpeb1


Sorted Z-values histogram for motif Cpeb1

Sorted Z-values for motif Cpeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cpeb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 59.412 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr3_+_5218546 47.303 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr3_+_5218516 45.175 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr3_-_63851251 41.789 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
 Plch1


phospholipase C, eta 1


chr1_+_6730051 41.551 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr2_-_51149100 41.389 ENSMUST00000154545.1
ENSMUST00000017288.2
 Rnd3

Rho family GTPase 3

chr1_-_138842429 37.529 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr2_-_18048784 37.291 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr1_+_6734827 34.675 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr3_+_5218589 32.662 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr1_+_6730135 29.658 ENSMUST00000155921.1
 St18
suppression of tumorigenicity 18
chr3_+_87948666 28.582 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr11_-_99024179 27.996 ENSMUST00000068031.7
 Top2a
topoisomerase (DNA) II alpha
chr2_-_137116624 27.826 ENSMUST00000028735.7
 Jag1
jagged 1
chr2_-_18048347 25.373 ENSMUST00000066885.5
 Skida1
SKI/DACH domain containing 1
chr14_-_48667508 23.902 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr17_+_43953191 20.541 ENSMUST00000044792.4
 Rcan2
regulator of calcineurin 2
chr9_+_96259246 20.501 ENSMUST00000179065.1
ENSMUST00000165768.2
 Tfdp2

transcription factor Dp 2

chr10_+_19356558 18.291 ENSMUST00000053225.5
 Olig3
oligodendrocyte transcription factor 3
chr12_-_54986328 18.220 ENSMUST00000038926.6
 Baz1a
bromodomain adjacent to zinc finger domain 1A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 178 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.8 105.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.0 44.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
2.6 39.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
7.5 37.5 GO:0035262 gonad morphogenesis(GO:0035262)
4.6 37.1 GO:0048625 myoblast fate commitment(GO:0048625)
7.7 31.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
2.8 30.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
7.0 28.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
5.6 27.8 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 27.5 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.2 27.2 GO:0006261 DNA-dependent DNA replication(GO:0006261)
1.6 25.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.4 24.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
4.4 22.0 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
1.7 21.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
3.7 18.3 GO:0097476 spinal cord motor neuron migration(GO:0097476)
6.0 18.0 GO:0060023 soft palate development(GO:0060023)
0.8 17.3 GO:0060009 Sertoli cell development(GO:0060009)
1.6 16.5 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
3.2 15.9 GO:0015671 oxygen transport(GO:0015671)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 109.7 GO:0032993 protein-DNA complex(GO:0032993)
0.1 60.0 GO:0005912 adherens junction(GO:0005912)
4.5 40.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 39.0 GO:0016607 nuclear speck(GO:0016607)
8.9 35.8 GO:0008623 CHRAC(GO:0008623)
0.3 33.7 GO:0005814 centriole(GO:0005814)
0.2 31.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
1.0 25.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 23.1 GO:0005794 Golgi apparatus(GO:0005794)
0.2 17.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 17.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.5 16.5 GO:0051233 spindle midzone(GO:0051233)
0.5 16.5 GO:1990391 DNA repair complex(GO:1990391)
7.9 15.9 GO:0005833 hemoglobin complex(GO:0005833)
0.0 14.0 GO:0005774 vacuolar membrane(GO:0005774)
1.0 13.9 GO:0042788 polysomal ribosome(GO:0042788)
2.8 11.1 GO:0045098 type III intermediate filament(GO:0045098)
1.0 11.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.7 10.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 10.2 GO:0005813 centrosome(GO:0005813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 129 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 131.4 GO:0001047 core promoter binding(GO:0001047)
0.2 131.3 GO:0008270 zinc ion binding(GO:0008270)
0.2 56.1 GO:0003924 GTPase activity(GO:0003924)
0.1 50.9 GO:0019904 protein domain specific binding(GO:0019904)
2.2 41.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 35.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.7 35.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 31.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
4.8 28.6 GO:0019841 retinol binding(GO:0019841)
7.0 28.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.8 27.7 GO:0005112 Notch binding(GO:0005112)
3.8 26.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 25.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.5 24.0 GO:0003680 AT DNA binding(GO:0003680)
0.7 21.7 GO:0032452 histone demethylase activity(GO:0032452)
3.4 20.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.4 20.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 17.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
3.2 15.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.5 15.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 34.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.8 30.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.6 27.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.5 24.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 24.2 PID_CDC42_PATHWAY CDC42 signaling events
0.5 21.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.6 21.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 21.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.6 20.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.5 18.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.3 12.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.5 11.3 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.6 11.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.2 8.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.6 8.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 8.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.3 8.1 NABA_COLLAGENS Genes encoding collagen proteins
0.2 7.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.2 7.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 6.6 PID_PLK1_PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 27.8 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.7 26.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
1.6 22.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 17.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 17.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.2 16.6 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.5 14.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.2 12.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.7 11.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 11.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 11.1 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 10.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 9.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 8.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.2 8.6 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.6 8.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.4 8.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3 8.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.3 8.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
2.6 7.7 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors