Motif ID: Creb1
Z-value: 1.633
Transcription factors associated with Creb1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Creb1 | ENSMUSG00000025958.8 | Creb1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Creb1 | mm10_v2_chr1_+_64532790_64532815 | 0.47 | 1.6e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.2 | 12.5 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 3.4 | 13.5 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 3.0 | 6.0 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
| 2.9 | 8.8 | GO:0072554 | arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) |
| 2.4 | 28.9 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 2.3 | 9.3 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 2.1 | 8.5 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 2.0 | 6.0 | GO:0097309 | cap1 mRNA methylation(GO:0097309) |
| 1.8 | 1.8 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
| 1.6 | 11.5 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 1.6 | 9.7 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 1.5 | 6.0 | GO:0001306 | age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) |
| 1.3 | 9.4 | GO:0051461 | regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 1.2 | 3.7 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 1.1 | 5.7 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 1.1 | 3.4 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 1.1 | 2.3 | GO:0035973 | aggrephagy(GO:0035973) |
| 1.1 | 5.4 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 1.1 | 3.2 | GO:0071579 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579) |
| 1.0 | 7.2 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 1.0 | 2.0 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 1.0 | 2.9 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
| 1.0 | 5.7 | GO:0045875 | DNA strand renaturation(GO:0000733) negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.9 | 6.4 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 0.8 | 2.5 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.8 | 4.0 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 0.8 | 2.4 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.8 | 3.1 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 0.7 | 8.2 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.7 | 2.2 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.7 | 3.5 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.7 | 2.0 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.7 | 3.3 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.7 | 2.6 | GO:0051311 | meiotic metaphase plate congression(GO:0051311) attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
| 0.6 | 6.4 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.6 | 1.9 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.6 | 1.8 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
| 0.6 | 2.3 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 0.5 | 4.9 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 0.5 | 3.2 | GO:0051189 | molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
| 0.5 | 3.2 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 0.5 | 4.7 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.5 | 1.6 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.5 | 4.1 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.5 | 3.6 | GO:0045078 | enucleate erythrocyte differentiation(GO:0043353) positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.5 | 2.5 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.5 | 2.0 | GO:0048296 | negative regulation of isotype switching(GO:0045829) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) |
| 0.5 | 3.3 | GO:0051004 | plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004) |
| 0.5 | 1.9 | GO:0006272 | DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272) |
| 0.5 | 8.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.4 | 1.8 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.4 | 2.7 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.4 | 9.3 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.4 | 1.8 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.4 | 2.6 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.4 | 1.3 | GO:0034182 | regulation of maintenance of sister chromatid cohesion(GO:0034091) positive regulation of maintenance of sister chromatid cohesion(GO:0034093) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 0.4 | 4.7 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.4 | 1.3 | GO:0016237 | lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157) |
| 0.4 | 1.2 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.4 | 1.6 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.4 | 1.6 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
| 0.4 | 1.1 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.4 | 2.2 | GO:0035878 | nail development(GO:0035878) |
| 0.4 | 2.8 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.3 | 3.5 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.3 | 1.0 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.3 | 2.0 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.3 | 2.9 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.3 | 1.3 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
| 0.3 | 0.9 | GO:0010751 | regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 0.3 | 8.8 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.3 | 1.2 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
| 0.3 | 2.6 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.3 | 1.4 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 0.3 | 0.8 | GO:0071707 | base-excision repair, gap-filling(GO:0006287) immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 0.3 | 1.9 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.3 | 1.6 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.3 | 2.6 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 0.2 | 2.2 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
| 0.2 | 0.5 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 0.2 | 1.9 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
| 0.2 | 1.0 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
| 0.2 | 2.8 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.2 | 0.7 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
| 0.2 | 5.0 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.2 | 0.7 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.2 | 7.4 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.2 | 0.6 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.2 | 0.8 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
| 0.2 | 0.8 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 0.2 | 0.6 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627) |
| 0.2 | 0.9 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.2 | 0.4 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
| 0.2 | 2.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.2 | 1.2 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.2 | 2.5 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 2.0 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.2 | 0.6 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.1 | 2.5 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.1 | 4.7 | GO:0007129 | synapsis(GO:0007129) |
| 0.1 | 1.7 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.1 | 2.9 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.1 | 1.1 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.1 | 1.6 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.1 | 2.3 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.1 | 1.5 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.1 | 5.6 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.1 | 1.7 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.1 | 3.8 | GO:0045879 | negative regulation of smoothened signaling pathway(GO:0045879) |
| 0.1 | 3.9 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.1 | 0.9 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 1.6 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.1 | 0.5 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.1 | 1.0 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.1 | 1.6 | GO:0034204 | lipid translocation(GO:0034204) |
| 0.1 | 5.1 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.1 | 3.6 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.1 | 4.7 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 0.4 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.1 | 0.5 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.1 | 0.7 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 0.1 | 0.9 | GO:0009125 | nucleoside monophosphate catabolic process(GO:0009125) |
| 0.1 | 4.1 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.1 | 6.7 | GO:0007098 | centrosome cycle(GO:0007098) |
| 0.1 | 0.6 | GO:0007292 | female gamete generation(GO:0007292) |
| 0.1 | 0.9 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.1 | 3.3 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.1 | 1.8 | GO:0045724 | positive regulation of cilium assembly(GO:0045724) |
| 0.1 | 0.8 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.1 | 0.2 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) |
| 0.1 | 0.2 | GO:2001140 | regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140) |
| 0.1 | 0.5 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 0.1 | 0.2 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 0.1 | 0.6 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.1 | 2.5 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 8.1 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 0.8 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 3.5 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.0 | 0.7 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.0 | 0.7 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.3 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 5.9 | GO:0007596 | blood coagulation(GO:0007596) |
| 0.0 | 0.2 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.0 | 0.4 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.0 | 0.3 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.0 | 0.1 | GO:0060743 | prostate gland stromal morphogenesis(GO:0060741) epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144) |
| 0.0 | 0.5 | GO:0008209 | androgen metabolic process(GO:0008209) |
| 0.0 | 0.5 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 2.3 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.0 | 0.0 | GO:0007521 | muscle cell fate determination(GO:0007521) |
| 0.0 | 2.5 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.0 | 0.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 3.2 | GO:0019827 | stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727) |
| 0.0 | 0.4 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.1 | GO:0034982 | mitochondrial protein processing(GO:0034982) |
| 0.0 | 0.4 | GO:0051452 | intracellular pH reduction(GO:0051452) |
| 0.0 | 0.2 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
| 0.0 | 0.1 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.0 | 0.1 | GO:0015817 | histidine transport(GO:0015817) |
| 0.0 | 4.5 | GO:0006816 | calcium ion transport(GO:0006816) |
| 0.0 | 3.0 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 0.0 | 4.4 | GO:0007283 | spermatogenesis(GO:0007283) |
| 0.0 | 0.3 | GO:0009994 | oocyte differentiation(GO:0009994) |
| 0.0 | 1.4 | GO:0060271 | cilium morphogenesis(GO:0060271) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 12.5 | GO:0008278 | cohesin complex(GO:0008278) |
| 1.8 | 8.8 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 1.5 | 6.0 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.8 | 3.3 | GO:0042827 | platelet dense granule(GO:0042827) |
| 0.8 | 2.5 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.8 | 2.3 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.7 | 9.7 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) mitotic spindle midzone(GO:1990023) |
| 0.7 | 6.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.7 | 4.1 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.6 | 6.0 | GO:0090543 | Flemming body(GO:0090543) |
| 0.6 | 31.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.6 | 8.6 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.6 | 4.5 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.6 | 1.7 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
| 0.6 | 3.3 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.6 | 9.4 | GO:0051286 | cell tip(GO:0051286) |
| 0.5 | 5.3 | GO:0090576 | RNA polymerase III transcription factor complex(GO:0090576) |
| 0.5 | 3.2 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 0.5 | 1.6 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.5 | 3.6 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.4 | 3.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.4 | 3.5 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.4 | 1.9 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.4 | 2.3 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.4 | 1.1 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
| 0.3 | 0.7 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.3 | 1.2 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.3 | 2.3 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.3 | 17.2 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.3 | 0.8 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.2 | 1.5 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.2 | 5.7 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.2 | 2.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.2 | 1.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.2 | 2.8 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.2 | 3.4 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.2 | 2.2 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 2.5 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 0.8 | GO:0032021 | NELF complex(GO:0032021) |
| 0.2 | 1.0 | GO:0030689 | Noc complex(GO:0030689) |
| 0.2 | 2.0 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.2 | 4.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.2 | 1.3 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.2 | 3.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.2 | 2.6 | GO:0000800 | lateral element(GO:0000800) |
| 0.2 | 3.2 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.2 | 2.8 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 0.7 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 0.2 | 16.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.2 | 5.2 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.2 | 1.7 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 1.3 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.2 | 2.9 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.2 | 3.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.2 | 0.5 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 4.9 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 1.3 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.1 | 0.6 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.1 | 2.9 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 8.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 0.9 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.1 | 13.0 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 2.2 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.5 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.1 | 3.3 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 4.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 1.9 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 4.7 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 6.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 3.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 2.8 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.1 | 8.5 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 5.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 1.6 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 5.5 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 2.7 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 5.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 0.9 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 2.5 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 0.8 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 0.3 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.0 | 0.9 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 8.1 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.5 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 1.6 | GO:0030529 | intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904) |
| 0.0 | 1.4 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 2.8 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 1.8 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 1.7 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 6.1 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 1.0 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.1 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.0 | 0.5 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.4 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.5 | GO:0005684 | U2-type spliceosomal complex(GO:0005684) |
| 0.0 | 0.3 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.2 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.1 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 5.6 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.8 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 0.3 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.1 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.0 | 0.8 | GO:0036064 | ciliary basal body(GO:0036064) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 9.7 | GO:0043515 | kinetochore binding(GO:0043515) |
| 1.7 | 5.0 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 1.5 | 6.0 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 1.2 | 8.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 1.2 | 7.2 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 1.2 | 9.4 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 1.2 | 9.4 | GO:0030911 | TPR domain binding(GO:0030911) |
| 1.1 | 5.7 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 1.0 | 28.9 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 1.0 | 3.0 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.9 | 3.5 | GO:0035851 | histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851) |
| 0.8 | 2.3 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.8 | 2.3 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.7 | 3.3 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.7 | 2.6 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.6 | 5.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.6 | 3.2 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.6 | 5.9 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.6 | 2.8 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.5 | 3.2 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.5 | 4.2 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) |
| 0.5 | 1.5 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.5 | 1.4 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.5 | 1.8 | GO:0004844 | mismatch base pair DNA N-glycosylase activity(GO:0000700) uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.4 | 2.2 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.4 | 4.7 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.4 | 3.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.4 | 1.3 | GO:0019779 | Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779) |
| 0.4 | 2.8 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.4 | 1.2 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
| 0.3 | 12.8 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.3 | 1.9 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.3 | 3.2 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.3 | 1.0 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 0.3 | 3.1 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.3 | 12.8 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.3 | 3.3 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.3 | 3.6 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.3 | 6.6 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.3 | 2.0 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.3 | 3.6 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.3 | 4.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.3 | 3.5 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.3 | 2.9 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.3 | 8.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 3.9 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.2 | 1.9 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.2 | 2.5 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.2 | 1.6 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.2 | 1.7 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.2 | 6.2 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.2 | 2.8 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.2 | 1.9 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.2 | 6.4 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.2 | 1.1 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.2 | 8.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 2.7 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.2 | 3.6 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.2 | 2.5 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 4.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 1.5 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.1 | 0.9 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.1 | 4.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 2.5 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.1 | 6.4 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.1 | 0.5 | GO:0035473 | lipase binding(GO:0035473) |
| 0.1 | 1.8 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.1 | 8.4 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 0.1 | 10.3 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 1.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 4.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 2.1 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.1 | 0.4 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine) methyltransferase activity(GO:0016433) |
| 0.1 | 1.8 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.1 | 3.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.1 | 0.6 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 2.3 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 0.8 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 0.9 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 0.9 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.1 | 0.7 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.1 | 7.4 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.1 | 2.5 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.1 | 0.7 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.2 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 1.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.9 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 0.1 | 1.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 0.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 2.0 | GO:0004407 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
| 0.1 | 1.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 0.5 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 0.0 | 1.5 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.6 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.0 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 0.0 | 3.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 7.8 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 1.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 8.4 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 1.6 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 3.7 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 6.7 | GO:0042623 | ATPase activity, coupled(GO:0042623) |
| 0.0 | 2.0 | GO:0005319 | lipid transporter activity(GO:0005319) |
| 0.0 | 11.3 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 1.5 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 1.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.4 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 14.6 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 2.9 | GO:0008514 | organic anion transmembrane transporter activity(GO:0008514) |
| 0.0 | 0.8 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 2.4 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.4 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.0 | 2.9 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
| 0.0 | 0.7 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 4.9 | GO:0061659 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 3.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.1 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.0 | 0.1 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 0.3 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.4 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 2.2 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 19.6 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.3 | 2.9 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.3 | 5.2 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.3 | 16.7 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.3 | 2.2 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 8.5 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.2 | 13.9 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.2 | 9.7 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.2 | 12.8 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.2 | 7.6 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 2.8 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 3.3 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.1 | 3.5 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 8.2 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
| 0.1 | 2.8 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
| 0.1 | 3.3 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 1.0 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 3.3 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 2.0 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
| 0.0 | 1.9 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.1 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.9 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 3.2 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
| 0.0 | 1.5 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.6 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.4 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.5 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 14.2 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.8 | 6.1 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.6 | 7.6 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.6 | 18.7 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.5 | 8.5 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.5 | 2.9 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.5 | 7.2 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.4 | 3.5 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.4 | 6.5 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.3 | 4.5 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.3 | 8.0 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.3 | 15.6 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.3 | 5.7 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.2 | 2.7 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.2 | 3.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.2 | 2.5 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.2 | 6.1 | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.2 | 4.9 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | Genes involved in Double-Strand Break Repair |
| 0.2 | 5.4 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.2 | 1.5 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.2 | 4.8 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.1 | 4.5 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 6.1 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 4.0 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 3.6 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 1.2 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 1.1 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.1 | 5.0 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.1 | 2.9 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 1.9 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.1 | 3.1 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 3.2 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 3.5 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 3.5 | REACTOME_SIGNALING_BY_ERBB4 | Genes involved in Signaling by ERBB4 |
| 0.1 | 1.6 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 1.3 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.1 | 3.9 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 1.6 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.1 | 7.5 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 2.5 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.6 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 3.3 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.5 | REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |
| 0.0 | 1.6 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 9.2 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.5 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.4 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 1.6 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.2 | REACTOME_ORC1_REMOVAL_FROM_CHROMATIN | Genes involved in Orc1 removal from chromatin |
| 0.0 | 0.6 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.6 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
