Motif ID: Crem_Jdp2

Z-value: 0.567

Transcription factors associated with Crem_Jdp2:

Gene SymbolEntrez IDGene Name
Crem ENSMUSG00000063889.10 Crem
Jdp2 ENSMUSG00000034271.9 Jdp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Jdp2mm10_v2_chr12_+_85599047_85599105-0.502.9e-06Click!
Cremmm10_v2_chr18_-_3337539_33376000.412.1e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Crem_Jdp2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 16.078 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr3_+_135212557 11.226 ENSMUST00000062893.7
Cenpe
centromere protein E
chr11_+_101468164 11.223 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr1_-_134079114 7.658 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr17_+_43952999 7.341 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr17_+_43953191 6.795 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr2_+_109280738 5.870 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr5_-_106458440 5.817 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr1_+_135729147 5.698 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr2_+_105668888 5.628 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr1_+_74791516 5.563 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr15_+_34238026 5.544 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr7_+_79500081 5.528 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr7_+_79500018 5.451 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr6_+_113531675 5.243 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr7_+_112679314 4.838 ENSMUST00000084705.5
ENSMUST00000059768.10
Tead1

TEA domain family member 1

chr2_+_105668935 4.584 ENSMUST00000142772.1
Pax6
paired box gene 6
chr4_+_8690399 4.575 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr11_-_88718223 4.559 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr11_-_84525514 4.398 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr4_+_11704439 4.103 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr1_+_184034381 4.019 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr7_-_142899985 3.920 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr14_+_47472628 3.906 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr14_+_47472547 3.892 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr7_+_112679327 3.761 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr11_+_113619318 3.728 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr3_-_36571952 3.694 ENSMUST00000029270.3
Ccna2
cyclin A2
chr6_+_14901344 3.668 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr3_+_125404072 3.607 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr7_-_137314394 3.604 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr3_+_31095052 3.602 ENSMUST00000118470.1
ENSMUST00000029194.5
ENSMUST00000123532.1
ENSMUST00000117728.1
Skil



SKI-like



chr5_-_124032214 3.497 ENSMUST00000040967.7
Vps37b
vacuolar protein sorting 37B (yeast)
chr3_+_145118564 3.371 ENSMUST00000098538.2
ENSMUST00000106192.2
ENSMUST00000029920.8
ENSMUST00000098539.2
Odf2l



outer dense fiber of sperm tails 2-like



chr11_+_84525669 3.331 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr11_+_84525647 3.135 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr3_+_125404292 3.053 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr13_+_15463202 2.967 ENSMUST00000130065.1
Gli3
GLI-Kruppel family member GLI3
chr15_+_25758755 2.814 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr13_+_113035111 2.786 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr11_-_100939357 2.707 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr5_-_69341699 2.698 ENSMUST00000054095.4
Kctd8
potassium channel tetramerisation domain containing 8
chr11_-_100939540 2.667 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr6_+_15196949 2.612 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr4_-_123750236 2.608 ENSMUST00000102636.3
Akirin1
akirin 1
chr7_-_144939823 2.576 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr11_-_100939457 2.537 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr11_+_64435315 2.515 ENSMUST00000058652.5
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr9_-_20976762 2.502 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr9_-_64172879 2.494 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
Zwilch



zwilch kinetochore protein



chr19_+_37376359 2.449 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr3_+_127553462 2.350 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr11_-_78165521 2.338 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr1_+_107511489 2.336 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_107511416 2.255 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_63273261 2.127 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chrX_-_56598069 2.091 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chrX_-_7188713 2.029 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr6_+_34598530 2.017 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr17_-_56476462 1.987 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chr13_+_23531044 1.985 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr2_-_23155864 1.974 ENSMUST00000028119.6
Mastl
microtubule associated serine/threonine kinase-like
chr10_-_92722356 1.915 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr17_+_72918298 1.897 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr9_-_96478596 1.887 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr9_-_52679429 1.884 ENSMUST00000098768.2
AI593442
expressed sequence AI593442
chr11_+_69324069 1.873 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr10_-_42583628 1.868 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr11_+_69324055 1.867 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr1_-_79440039 1.862 ENSMUST00000049972.4
Scg2
secretogranin II
chr14_+_54476100 1.857 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr6_+_34598500 1.851 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr3_-_65958236 1.831 ENSMUST00000029416.7
Ccnl1
cyclin L1
chr8_+_72135247 1.816 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr14_+_14012491 1.815 ENSMUST00000022257.2
Atxn7
ataxin 7
chr9_-_96478660 1.797 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr7_+_139389072 1.763 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr8_-_24438937 1.720 ENSMUST00000052622.4
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr6_+_124808885 1.670 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr7_-_30664986 1.657 ENSMUST00000019697.8
Haus5
HAUS augmin-like complex, subunit 5
chr13_-_64274879 1.656 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr11_-_88718165 1.653 ENSMUST00000107908.1
Msi2
musashi RNA-binding protein 2
chr11_+_69965396 1.643 ENSMUST00000018713.6
Cldn7
claudin 7
chr3_+_67374091 1.620 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr3_+_67374116 1.620 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr12_+_52097737 1.606 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr11_+_69323963 1.586 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr4_+_115737738 1.566 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr11_-_69323768 1.531 ENSMUST00000092973.5
Cntrob
centrobin, centrosomal BRCA2 interacting protein
chr16_+_38562806 1.528 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr6_-_86669136 1.523 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr17_-_31855782 1.492 ENSMUST00000024839.4
Sik1
salt inducible kinase 1
chr10_+_44268328 1.454 ENSMUST00000039286.4
Atg5
autophagy related 5
chr10_+_96616998 1.451 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr5_+_142960343 1.446 ENSMUST00000031565.8
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr11_+_108682602 1.409 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr2_-_3474954 1.389 ENSMUST00000060618.6
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr10_-_128176568 1.383 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr16_+_38562821 1.374 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr19_+_8850785 1.354 ENSMUST00000096257.2
Lrrn4cl
LRRN4 C-terminal like
chr13_-_54688065 1.349 ENSMUST00000125871.1
Rnf44
ring finger protein 44
chr3_+_88214474 1.341 ENSMUST00000181356.1
ENSMUST00000181396.1
Gm3764

predicted gene 3764

chr4_-_131838231 1.335 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr17_-_26508463 1.325 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr6_-_30304513 1.306 ENSMUST00000094543.2
ENSMUST00000102993.3
Ube2h

ubiquitin-conjugating enzyme E2H

chr2_-_3475027 1.302 ENSMUST00000027956.2
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr3_+_40800054 1.291 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr9_-_105395237 1.268 ENSMUST00000140851.1
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chr2_-_36136773 1.228 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chrX_-_21061981 1.214 ENSMUST00000040628.5
ENSMUST00000115333.2
ENSMUST00000115334.1
Zfp182


zinc finger protein 182


chr10_+_80494835 1.173 ENSMUST00000051773.8
Onecut3
one cut domain, family member 3
chr10_-_128804353 1.170 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr7_-_118533298 1.159 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chrX_-_111697069 1.145 ENSMUST00000113422.2
ENSMUST00000038472.5
Hdx

highly divergent homeobox

chr17_+_36958623 1.140 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr17_-_27907706 1.120 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_+_46012810 1.107 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr7_-_118584669 1.106 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr2_+_19909769 1.092 ENSMUST00000114610.1
Etl4
enhancer trap locus 4
chr5_+_24164963 1.085 ENSMUST00000049887.6
Nupl2
nucleoporin like 2
chr6_+_14901440 1.069 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr9_+_64179289 1.061 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chr8_+_40511769 1.055 ENSMUST00000098817.2
Vps37a
vacuolar protein sorting 37A (yeast)
chr2_-_36136602 1.028 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chr17_+_36958571 1.024 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr2_+_156840077 1.023 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr12_-_27342696 0.998 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr2_+_145785980 0.995 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chr13_+_42052015 0.982 ENSMUST00000060148.5
Hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr12_+_73286868 0.975 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr13_-_54688184 0.965 ENSMUST00000150806.1
ENSMUST00000125927.1
Rnf44

ring finger protein 44

chr6_+_6863269 0.956 ENSMUST00000160937.2
ENSMUST00000171311.1
Dlx6

distal-less homeobox 6

chr4_-_132075250 0.944 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr2_+_49619277 0.937 ENSMUST00000028102.7
Kif5c
kinesin family member 5C
chr13_+_19623163 0.930 ENSMUST00000002883.5
Sfrp4
secreted frizzled-related protein 4
chr9_+_74861888 0.902 ENSMUST00000056006.9
Onecut1
one cut domain, family member 1
chr3_+_129199919 0.898 ENSMUST00000029657.9
ENSMUST00000106382.4
Pitx2

paired-like homeodomain transcription factor 2

chr14_+_56887795 0.897 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr10_-_128891674 0.887 ENSMUST00000026408.6
Gdf11
growth differentiation factor 11
chr10_-_115587739 0.870 ENSMUST00000020350.8
Lgr5
leucine rich repeat containing G protein coupled receptor 5
chr8_-_110997764 0.868 ENSMUST00000040416.7
Ddx19a
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
chr9_+_46012822 0.864 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr13_-_64274962 0.862 ENSMUST00000039318.8
Cdc14b
CDC14 cell division cycle 14B
chr5_-_51553896 0.857 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr2_+_167777467 0.840 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr2_+_122738495 0.830 ENSMUST00000005954.8
Bloc1s6
biogenesis of organelles complex-1, subunit 6, pallidin
chr7_+_63444741 0.827 ENSMUST00000058476.7
Otud7a
OTU domain containing 7A
chr9_+_102718424 0.792 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chr11_-_102185239 0.783 ENSMUST00000021297.5
Lsm12
LSM12 homolog (S. cerevisiae)
chr8_+_92674289 0.782 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr4_+_32238713 0.778 ENSMUST00000108180.2
Bach2
BTB and CNC homology 2
chr17_+_84511832 0.769 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr7_-_65370908 0.753 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr8_+_22757744 0.749 ENSMUST00000033941.5
Plat
plasminogen activator, tissue
chr7_+_125707945 0.747 ENSMUST00000148701.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr5_-_5664196 0.746 ENSMUST00000061008.3
ENSMUST00000054865.6
A330021E22Rik

RIKEN cDNA A330021E22 gene

chr19_-_42129043 0.743 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr6_-_39725193 0.727 ENSMUST00000101497.3
Braf
Braf transforming gene
chr13_-_54688246 0.722 ENSMUST00000122935.1
ENSMUST00000128257.1
Rnf44

ring finger protein 44

chr3_+_138143429 0.716 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr13_-_19395728 0.712 ENSMUST00000039694.7
Stard3nl
STARD3 N-terminal like
chr7_+_139248477 0.706 ENSMUST00000093993.3
ENSMUST00000172136.1
Pwwp2b

PWWP domain containing 2B

chr10_+_72654873 0.700 ENSMUST00000105431.1
ENSMUST00000160337.1
Zwint

ZW10 interactor

chr2_-_120609319 0.694 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr17_-_45573253 0.674 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr4_+_115737754 0.673 ENSMUST00000106522.2
Efcab14
EF-hand calcium binding domain 14
chr11_+_20631956 0.670 ENSMUST00000109586.2
Sertad2
SERTA domain containing 2
chr6_-_39725448 0.639 ENSMUST00000002487.8
Braf
Braf transforming gene
chr1_+_75236439 0.636 ENSMUST00000082158.6
ENSMUST00000055223.7
Dnajb2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr10_+_80629646 0.635 ENSMUST00000085435.5
Csnk1g2
casein kinase 1, gamma 2
chr6_+_134035691 0.633 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr11_-_113751813 0.632 ENSMUST00000053536.4
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr2_+_130295148 0.621 ENSMUST00000110288.2
Ebf4
early B cell factor 4
chr4_+_43578709 0.616 ENSMUST00000107886.2
ENSMUST00000117140.1
Rgp1

RGP1 retrograde golgi transport homolog (S. cerevisiae)

chr7_-_38271310 0.615 ENSMUST00000032585.6
Pop4
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chr15_-_12321899 0.610 ENSMUST00000180521.1
1810049J17Rik
RIKEN cDNA 1810049J17 gene
chr3_+_138143483 0.606 ENSMUST00000162864.1
Trmt10a
tRNA methyltransferase 10A
chr2_-_120609283 0.606 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr5_-_97111565 0.599 ENSMUST00000112969.3
Paqr3
progestin and adipoQ receptor family member III
chr3_-_138143352 0.586 ENSMUST00000098580.2
Mttp
microsomal triglyceride transfer protein
chr5_-_5559521 0.574 ENSMUST00000088842.4
ENSMUST00000115441.2
Gtpbp10

GTP-binding protein 10 (putative)

chr16_+_5050012 0.564 ENSMUST00000052449.5
Ubn1
ubinuclein 1
chr8_+_92674826 0.562 ENSMUST00000167261.2
Irx6
Iroquois related homeobox 6 (Drosophila)
chr11_-_102185202 0.561 ENSMUST00000107156.2
Lsm12
LSM12 homolog (S. cerevisiae)
chr16_+_22009471 0.556 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr2_-_120609500 0.553 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr5_-_5559501 0.550 ENSMUST00000119521.1
Gtpbp10
GTP-binding protein 10 (putative)
chr13_-_100104064 0.546 ENSMUST00000038104.5
Bdp1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chrX_-_8145713 0.545 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
Rbm3


RNA binding motif protein 3


chr15_+_12321472 0.541 ENSMUST00000059680.5
Golph3
golgi phosphoprotein 3
chr2_+_162931520 0.537 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr7_-_44748306 0.529 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
Zfp473


zinc finger protein 473


chr11_-_53457110 0.524 ENSMUST00000084653.3
Gm10447
predicted gene 10447
chr15_+_59648644 0.517 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr12_+_72761211 0.515 ENSMUST00000021514.8
Ppm1a
protein phosphatase 1A, magnesium dependent, alpha isoform
chr1_+_38987806 0.514 ENSMUST00000027247.5
Pdcl3
phosducin-like 3
chr13_-_99516537 0.513 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr7_+_125707893 0.511 ENSMUST00000069660.6
ENSMUST00000142464.1
D430042O09Rik

RIKEN cDNA D430042O09 gene

chr3_+_129199878 0.504 ENSMUST00000174661.2
Pitx2
paired-like homeodomain transcription factor 2
chr3_-_146108047 0.502 ENSMUST00000160285.1
Wdr63
WD repeat domain 63

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 16.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.0 10.2 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
2.0 7.9 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
1.9 11.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
1.5 4.6 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.5 4.4 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
1.2 3.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
1.1 3.3 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.0 3.9 GO:0042414 epinephrine metabolic process(GO:0042414)
0.8 4.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.7 5.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.7 11.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.7 7.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.7 13.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.7 6.0 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.6 5.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.6 1.8 GO:0035973 aggrephagy(GO:0035973)
0.6 6.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.5 2.1 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.5 4.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.5 2.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.5 7.5 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.5 4.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.4 1.7 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.4 3.7 GO:0030432 peristalsis(GO:0030432)
0.4 2.0 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.4 1.9 GO:0021764 amygdala development(GO:0021764)
0.4 1.9 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.4 1.5 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.4 1.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 2.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3 1.0 GO:0060022 hard palate development(GO:0060022) soft palate development(GO:0060023)
0.3 5.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 1.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 0.9 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.3 3.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.3 1.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 3.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 0.9 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.3 1.2 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.3 0.8 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 2.7 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.3 1.3 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.2 0.5 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.2 1.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 1.7 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.2 0.7 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.2 1.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 0.9 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 2.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 1.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 0.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 2.1 GO:0006824 cobalt ion transport(GO:0006824)
0.2 1.8 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 0.5 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 5.8 GO:0001709 cell fate determination(GO:0001709)
0.2 0.9 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.2 5.0 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.7 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.4 GO:0021603 cranial nerve formation(GO:0021603)
0.1 1.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.4 GO:0010958 regulation of amino acid import(GO:0010958)
0.1 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 2.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 1.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.6 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.5 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.3 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.8 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.5 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.8 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.8 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.6 GO:0097152 vitellogenesis(GO:0007296) mesenchymal cell apoptotic process(GO:0097152)
0.1 1.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.5 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.1 0.4 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.2 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 5.7 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.3 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 0.4 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.1 3.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 2.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 2.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 0.6 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 1.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 1.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0 0.1 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.5 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.9 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.6 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 1.2 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.4 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 1.1 GO:0048536 spleen development(GO:0048536)
0.0 4.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 2.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0030825 positive regulation of cGMP metabolic process(GO:0030825) positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 2.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.8 GO:0035329 hippo signaling(GO:0035329)
0.0 1.6 GO:0051225 spindle assembly(GO:0051225)
0.0 0.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 1.8 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.4 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.0 1.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0034204 lipid translocation(GO:0034204)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.3 GO:0003016 respiratory system process(GO:0003016)
0.0 0.4 GO:0050982 detection of mechanical stimulus(GO:0050982)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.3 3.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.2 3.7 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.2 15.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.8 2.5 GO:1990423 RZZ complex(GO:1990423)
0.5 3.7 GO:0001940 male pronucleus(GO:0001940)
0.5 4.6 GO:0000813 ESCRT I complex(GO:0000813)
0.5 1.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.5 1.9 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.4 3.9 GO:0030478 actin cap(GO:0030478)
0.3 5.3 GO:0030008 TRAPP complex(GO:0030008)
0.2 1.3 GO:0098536 deuterosome(GO:0098536)
0.2 4.1 GO:0051233 spindle midzone(GO:0051233)
0.2 1.6 GO:0070652 HAUS complex(GO:0070652)
0.1 1.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.3 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.4 GO:0071437 invadopodium(GO:0071437)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 2.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 2.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 3.2 GO:0097546 ciliary base(GO:0097546)
0.1 6.0 GO:0005844 polysome(GO:0005844)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 4.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.1 8.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 0.6 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 2.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.9 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 4.3 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 11.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.7 GO:0000922 spindle pole(GO:0000922)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 12.8 GO:0016604 nuclear body(GO:0016604)
0.0 5.5 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0060293 SMN-Sm protein complex(GO:0034719) P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.0 GO:0016234 inclusion body(GO:0016234)
0.0 0.5 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.9 GO:0000790 nuclear chromatin(GO:0000790)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 11.2 GO:0043515 kinetochore binding(GO:0043515)
2.2 13.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2 3.7 GO:0004994 somatostatin receptor activity(GO:0004994)
1.0 6.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.8 3.9 GO:0035240 dopamine binding(GO:0035240)
0.7 6.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 10.2 GO:0003680 AT DNA binding(GO:0003680)
0.5 2.7 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.5 1.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.5 0.9 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.5 3.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.4 1.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 8.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 2.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 5.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 2.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 1.6 GO:0042731 PH domain binding(GO:0042731)
0.3 2.1 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.3 6.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.0 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 3.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 2.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 1.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 0.6 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.2 1.6 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.2 39.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 2.3 GO:0031996 thioesterase binding(GO:0031996)
0.2 5.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 0.5 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.2 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.5 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 1.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 4.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 5.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 4.8 GO:0005109 frizzled binding(GO:0005109)
0.1 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 3.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 4.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 4.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.7 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.8 GO:0071253 connexin binding(GO:0071253)
0.1 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 2.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 8.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 2.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 3.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 2.2 GO:0030507 spectrin binding(GO:0030507)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.5 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 1.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.2 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 1.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 1.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 3.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.2 ST_STAT3_PATHWAY STAT3 Pathway
0.4 6.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 10.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 13.5 PID_PLK1_PATHWAY PLK1 signaling events
0.2 8.9 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 5.2 PID_BARD1_PATHWAY BARD1 signaling events
0.1 3.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 1.4 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 6.4 PID_CDC42_PATHWAY CDC42 signaling events
0.1 3.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 0.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 8.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 3.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 0.7 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.1 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID_MYC_PATHWAY C-MYC pathway
0.0 3.7 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.2 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 3.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 1.2 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.7 7.9 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.6 4.6 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 5.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 3.9 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.3 8.3 REACTOME_KINESINS Genes involved in Kinesins
0.3 8.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 1.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 3.7 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 7.1 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 6.1 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.7 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.9 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.4 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 2.2 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.9 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 4.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.1 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.1 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 2.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.6 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 3.5 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives