Motif ID: Dbp

Z-value: 1.090


Transcription factors associated with Dbp:

Gene SymbolEntrez IDGene Name
Dbp ENSMUSG00000059824.4 Dbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbpmm10_v2_chr7_+_45705088_45705292-0.537.4e-07Click!


Activity profile for motif Dbp.

activity profile for motif Dbp


Sorted Z-values histogram for motif Dbp

Sorted Z-values for motif Dbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Dbp

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_123264076 19.616 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr10_+_85386813 12.786 ENSMUST00000105307.1
ENSMUST00000020231.3
Btbd11

BTB (POZ) domain containing 11

chr8_+_68880491 11.947 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr3_-_26133734 11.336 ENSMUST00000108308.3
ENSMUST00000075054.4
Nlgn1

neuroligin 1

chr12_+_61523889 10.955 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr5_-_44799643 10.470 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chrX_-_72656135 9.322 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr5_-_92042630 9.141 ENSMUST00000113140.1
ENSMUST00000113143.1
Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr5_+_150259922 9.111 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr1_+_66386968 8.939 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chrX_-_165327376 8.879 ENSMUST00000058787.8
Glra2
glycine receptor, alpha 2 subunit
chrX_-_43167817 8.791 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr10_-_64090265 8.642 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr6_-_91807424 8.315 ENSMUST00000162300.1
Grip2
glutamate receptor interacting protein 2
chr16_+_7069825 7.815 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_28813125 7.792 ENSMUST00000029964.5
ENSMUST00000080934.4
Epha7

Eph receptor A7

chr4_+_28813152 7.612 ENSMUST00000108194.2
ENSMUST00000108191.1
Epha7

Eph receptor A7

chr6_-_91807318 7.487 ENSMUST00000159684.1
Grip2
glutamate receptor interacting protein 2
chr10_+_99263224 7.396 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr14_-_93888732 7.216 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr5_-_51553896 7.149 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr2_+_65845833 6.944 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr14_-_102982630 6.870 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr9_-_112187766 6.816 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr10_-_64090241 6.681 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr2_+_65845767 6.642 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr9_-_49798729 6.366 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr2_+_164960809 6.332 ENSMUST00000124372.1
Slc12a5
solute carrier family 12, member 5
chr10_+_90576708 6.314 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chr10_+_90576777 6.232 ENSMUST00000183136.1
ENSMUST00000182595.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr9_-_49798905 6.161 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr5_+_98854434 6.121 ENSMUST00000031278.4
Bmp3
bone morphogenetic protein 3
chr8_+_70501116 6.095 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr6_-_99520949 5.811 ENSMUST00000176565.1
Foxp1
forkhead box P1
chr1_+_143640664 5.752 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr7_-_119184374 5.718 ENSMUST00000084650.4
Gpr139
G protein-coupled receptor 139
chr7_-_19861299 5.433 ENSMUST00000014830.7
Ceacam16
carcinoembryonic antigen-related cell adhesion molecule 16
chr10_+_90576872 5.380 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr10_+_90576570 5.377 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr7_+_57591147 5.376 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr15_-_37459327 5.249 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr9_+_53771499 5.221 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr15_-_37458523 5.191 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr10_-_121311034 4.926 ENSMUST00000064107.5
Tbc1d30
TBC1 domain family, member 30
chr3_-_89322883 4.827 ENSMUST00000029673.5
Efna3
ephrin A3
chr8_+_54954728 4.776 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chrX_-_44790179 4.758 ENSMUST00000060481.2
Dcaf12l1
DDB1 and CUL4 associated factor 12-like 1
chr2_+_169632996 4.735 ENSMUST00000109159.2
Tshz2
teashirt zinc finger family member 2
chr10_+_90576678 4.635 ENSMUST00000182284.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr19_-_46327121 4.537 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr18_+_23803962 4.492 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr9_-_112187898 4.474 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr2_+_107290590 4.462 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr16_-_34513944 4.389 ENSMUST00000151491.1
ENSMUST00000114960.2
Kalrn

kalirin, RhoGEF kinase

chr1_-_37496095 4.378 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr11_-_37235882 4.341 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr17_+_68837062 4.278 ENSMUST00000178545.1
Tmem200c
transmembrane protein 200C
chr15_+_4375462 4.257 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr3_+_134236483 4.233 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr10_+_90576252 4.199 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr9_-_4796218 4.185 ENSMUST00000027020.6
ENSMUST00000063508.7
ENSMUST00000163309.1
Gria4


glutamate receptor, ionotropic, AMPA4 (alpha 4)


chr19_+_26748268 4.184 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chrX_-_44790146 4.158 ENSMUST00000115056.1
Dcaf12l1
DDB1 and CUL4 associated factor 12-like 1
chr19_-_28911879 4.137 ENSMUST00000179171.1
AC163993.1
AC163993.1
chr6_-_99521153 3.989 ENSMUST00000177227.1
Foxp1
forkhead box P1
chr13_+_109926832 3.896 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr2_+_68117713 3.781 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr16_-_34514084 3.775 ENSMUST00000089655.5
Kalrn
kalirin, RhoGEF kinase
chr15_-_79834323 3.759 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr

neuronal pentraxin receptor

chr11_-_30198232 3.688 ENSMUST00000102838.3
Sptbn1
spectrin beta, non-erythrocytic 1
chr11_-_74897052 3.667 ENSMUST00000057631.5
ENSMUST00000081799.5
Sgsm2

small G protein signaling modulator 2

chr13_-_102906046 3.581 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr14_-_76556662 3.547 ENSMUST00000064517.7
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr1_-_134234492 3.405 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr2_-_52558539 3.396 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr19_+_26605106 3.365 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr1_-_64122256 3.360 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr11_-_54860564 3.348 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr11_-_42000834 3.289 ENSMUST00000070725.4
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr18_+_34247685 3.262 ENSMUST00000066133.6
Apc
adenomatosis polyposis coli
chr6_-_113501818 3.168 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr1_+_33908172 3.155 ENSMUST00000182513.1
ENSMUST00000183034.1
Dst

dystonin

chr2_+_180042496 3.120 ENSMUST00000041126.8
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr7_-_75308373 3.094 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b
chr14_+_70077375 3.093 ENSMUST00000035908.1
Egr3
early growth response 3
chr3_+_109573907 3.060 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr18_-_36197343 3.060 ENSMUST00000115713.1
ENSMUST00000115712.1
Nrg2

neuregulin 2

chr2_-_6884940 3.041 ENSMUST00000183091.1
ENSMUST00000182851.1
Celf2

CUGBP, Elav-like family member 2

chrX_-_59166080 2.987 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr13_+_117602439 2.970 ENSMUST00000006991.7
Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr13_-_47014814 2.968 ENSMUST00000052747.2
Nhlrc1
NHL repeat containing 1
chrX_+_120290259 2.952 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
Pcdh11x


protocadherin 11 X-linked


chr1_+_140246216 2.949 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
Kcnt2



potassium channel, subfamily T, member 2



chr18_+_37489465 2.949 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr2_-_140671400 2.909 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr7_+_45785331 2.869 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr4_+_109343029 2.847 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr2_-_140671440 2.846 ENSMUST00000099301.1
Flrt3
fibronectin leucine rich transmembrane protein 3
chr3_-_103737995 2.814 ENSMUST00000029440.8
Olfml3
olfactomedin-like 3
chr2_-_102400863 2.814 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr1_+_11414089 2.799 ENSMUST00000048613.7
ENSMUST00000171690.2
ENSMUST00000137824.1
ENSMUST00000135014.1
ENSMUST00000179089.1
A830018L16Rik



A830018L16Rik
RIKEN cDNA A830018L16 gene



RIKEN cDNA A830018L16 gene
chr2_-_6884975 2.676 ENSMUST00000114924.3
ENSMUST00000170438.1
ENSMUST00000114934.4
Celf2


CUGBP, Elav-like family member 2


chr5_+_71699918 2.663 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr15_-_44428303 2.646 ENSMUST00000038719.6
Nudcd1
NudC domain containing 1
chr18_+_37504264 2.565 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr1_+_34121250 2.533 ENSMUST00000183006.1
Dst
dystonin
chr2_-_140671462 2.467 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr7_-_127021205 2.429 ENSMUST00000159916.1
Prrt2
proline-rich transmembrane protein 2
chr17_-_85090204 2.427 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr3_+_4211716 2.420 ENSMUST00000170943.1
Gm8775
predicted gene 8775
chr5_-_103211251 2.407 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr19_-_56822161 2.386 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr14_-_61556881 2.383 ENSMUST00000022497.8
Spryd7
SPRY domain containing 7
chr3_+_125404072 2.369 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr9_+_32224457 2.343 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr3_+_84925476 2.289 ENSMUST00000107675.1
Fbxw7
F-box and WD-40 domain protein 7
chr4_+_5644084 2.277 ENSMUST00000054857.6
Fam110b
family with sequence similarity 110, member B
chr14_-_26534870 2.228 ENSMUST00000139075.1
ENSMUST00000102956.1
Slmap

sarcolemma associated protein

chr3_+_13946368 2.209 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr8_+_84415348 2.197 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr19_-_31664356 2.187 ENSMUST00000073581.5
Prkg1
protein kinase, cGMP-dependent, type I
chr3_+_118430299 2.178 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr3_+_125404292 2.162 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr13_+_113794505 2.104 ENSMUST00000091201.6
Arl15
ADP-ribosylation factor-like 15
chr9_-_51077064 2.099 ENSMUST00000098782.3
Layn
layilin
chr14_-_61556746 2.062 ENSMUST00000100496.4
Spryd7
SPRY domain containing 7
chr2_+_156196642 2.052 ENSMUST00000037401.8
Phf20
PHD finger protein 20
chr5_+_65537209 2.051 ENSMUST00000142407.1
Ube2k
ubiquitin-conjugating enzyme E2K
chrX_+_37126777 2.032 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr13_-_102905740 1.882 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr15_-_82912134 1.882 ENSMUST00000048966.5
ENSMUST00000109510.2
Tcf20

transcription factor 20

chr4_-_119538769 1.873 ENSMUST00000079611.6
AA415398
expressed sequence AA415398
chr18_+_37496997 1.870 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr9_+_32224246 1.857 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr9_+_59589288 1.797 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr2_+_35691893 1.783 ENSMUST00000065001.5
Dab2ip
disabled 2 interacting protein
chr3_+_18054258 1.764 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr2_-_65238625 1.741 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobll1


Cobl-like 1


chr8_-_115707778 1.721 ENSMUST00000109104.1
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr16_+_19028232 1.705 ENSMUST00000074116.4
Gm10088
predicted gene 10088
chr6_-_29216301 1.680 ENSMUST00000162739.1
ENSMUST00000162099.1
ENSMUST00000159124.1
Impdh1


inosine 5'-phosphate dehydrogenase 1


chr6_-_35133731 1.624 ENSMUST00000114993.2
ENSMUST00000114989.2
ENSMUST00000044163.6
Cnot4


CCR4-NOT transcription complex, subunit 4


chr3_-_80802789 1.608 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr17_-_47691403 1.606 ENSMUST00000113299.1
ENSMUST00000152214.1
Gm21981
Prickle4
predicted gene 21981
prickle homolog 4 (Drosophila)
chr16_+_91225550 1.602 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr5_-_23616528 1.600 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr6_+_36388055 1.599 ENSMUST00000172278.1
Chrm2
cholinergic receptor, muscarinic 2, cardiac
chr11_-_114066174 1.584 ENSMUST00000041627.7
Sdk2
sidekick homolog 2 (chicken)
chr19_-_8819278 1.579 ENSMUST00000088092.5
Ttc9c
tetratricopeptide repeat domain 9C
chr10_-_30655859 1.567 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr17_+_8525369 1.505 ENSMUST00000115715.1
Pde10a
phosphodiesterase 10A
chr7_-_16917184 1.458 ENSMUST00000173139.1
Calm3
calmodulin 3
chr18_+_37484955 1.443 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr9_+_107400043 1.434 ENSMUST00000166799.1
ENSMUST00000170737.1
Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr7_-_118705708 1.423 ENSMUST00000038791.8
Gde1
glycerophosphodiester phosphodiesterase 1
chr6_+_51523901 1.419 ENSMUST00000049152.8
Snx10
sorting nexin 10
chr14_-_30353468 1.416 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr4_-_36136463 1.406 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr7_+_30712209 1.402 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr17_+_71204647 1.387 ENSMUST00000126681.1
Lpin2
lipin 2
chr12_-_84450944 1.372 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr1_+_60181495 1.364 ENSMUST00000160834.1
Nbeal1
neurobeachin like 1
chr6_-_23248264 1.349 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr11_-_120991305 1.341 ENSMUST00000018274.3
Csnk1d
casein kinase 1, delta
chr5_+_65537267 1.327 ENSMUST00000122141.1
Ube2k
ubiquitin-conjugating enzyme E2K
chr5_+_107497762 1.321 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chrX_+_112604274 1.283 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr1_+_179961110 1.277 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr1_+_127306706 1.271 ENSMUST00000171405.1
Mgat5
mannoside acetylglucosaminyltransferase 5
chr10_+_94550852 1.268 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3

transmembrane and coiled coil domains 3

chr3_-_50443603 1.257 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr10_+_36507013 1.237 ENSMUST00000168572.1
Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr18_+_63708689 1.236 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr13_+_55464237 1.186 ENSMUST00000046533.7
Prr7
proline rich 7 (synaptic)
chr12_+_71015966 1.181 ENSMUST00000046305.5
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr13_+_24614608 1.163 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr11_-_102556122 1.155 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr15_+_44428073 1.155 ENSMUST00000060652.3
Eny2
enhancer of yellow 2 homolog (Drosophila)
chr9_-_60649793 1.147 ENSMUST00000053171.7
Lrrc49
leucine rich repeat containing 49
chr3_-_146781351 1.139 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr19_-_23652780 1.136 ENSMUST00000035849.3
1700028P14Rik
RIKEN cDNA 1700028P14 gene
chr13_-_94246532 1.133 ENSMUST00000153558.1
Scamp1
secretory carrier membrane protein 1
chr5_+_107497718 1.101 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr2_+_19199266 1.066 ENSMUST00000114640.2
ENSMUST00000049255.6
Armc3

armadillo repeat containing 3

chr2_-_80447625 1.042 ENSMUST00000028389.3
Frzb
frizzled-related protein
chr11_+_50225315 0.996 ENSMUST00000041725.7
Mgat4b
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chrX_-_88115632 0.986 ENSMUST00000113966.1
ENSMUST00000113964.1
Il1rapl1

interleukin 1 receptor accessory protein-like 1

chr5_+_120431770 0.978 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chr6_+_134830216 0.960 ENSMUST00000111937.1
Crebl2
cAMP responsive element binding protein-like 2
chr1_-_183147461 0.959 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr2_-_58052832 0.928 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr2_-_72980402 0.922 ENSMUST00000066003.6
ENSMUST00000102689.3
Sp3

trans-acting transcription factor 3

chr8_+_23669653 0.909 ENSMUST00000042352.4
Zmat4
zinc finger, matrin type 4
chr9_+_107399858 0.907 ENSMUST00000085092.5
ENSMUST00000164988.2
Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr9_+_66350465 0.904 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chrX_+_159708593 0.894 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr11_+_24078173 0.879 ENSMUST00000109514.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr5_+_121795034 0.878 ENSMUST00000162327.1
Atxn2
ataxin 2
chr1_+_177444653 0.871 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr1_-_172258410 0.855 ENSMUST00000111243.1
Atp1a4
ATPase, Na+/K+ transporting, alpha 4 polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
3.6 10.9 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
3.0 11.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
2.7 8.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
2.7 32.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
2.6 15.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
2.5 7.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
1.8 7.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
1.6 15.8 GO:0014824 artery smooth muscle contraction(GO:0014824)
1.5 7.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.5 8.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
1.3 11.3 GO:0071420 cellular response to histamine(GO:0071420)
1.2 20.2 GO:1902993 positive regulation of amyloid precursor protein catabolic process(GO:1902993)
1.1 3.4 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.1 9.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.0 8.2 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
1.0 6.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.0 9.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.0 3.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.0 9.8 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.8 7.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.8 3.3 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.7 2.2 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.7 3.4 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.7 12.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.6 2.8 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.6 10.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.5 1.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5 3.7 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.5 3.0 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.5 1.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 2.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.5 2.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.5 1.4 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.4 2.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 1.7 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.4 2.6 GO:0097264 self proteolysis(GO:0097264)
0.4 2.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 4.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.4 7.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.4 3.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.4 1.8 GO:0036324 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.3 1.0 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.3 1.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 1.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.3 1.6 GO:0035063 nuclear speck organization(GO:0035063)
0.3 1.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 3.9 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 0.3 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.3 3.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 0.8 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 17.0 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.2 19.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 5.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.7 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 11.3 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 8.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 1.0 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.2 6.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 0.5 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.2 1.8 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.2 4.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 4.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2 2.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 3.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 2.8 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 10.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 0.4 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 2.4 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 5.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 10.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 3.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 1.7 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 4.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 1.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 1.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 1.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.4 GO:0010155 regulation of proton transport(GO:0010155)
0.1 1.0 GO:0060539 diaphragm development(GO:0060539)
0.1 4.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 1.8 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.9 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.8 GO:0043312 neutrophil degranulation(GO:0043312)
0.1 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 1.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.1 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.8 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 3.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 6.6 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 3.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 4.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 3.7 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 3.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223) progesterone secretion(GO:0042701)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 3.4 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 1.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.3 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 1.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.4 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.0 4.6 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 2.3 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0021783 facial nerve development(GO:0021561) rhombomere morphogenesis(GO:0021593) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) preganglionic parasympathetic fiber development(GO:0021783) parasympathetic nervous system development(GO:0048486)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.9 GO:0021766 hippocampus development(GO:0021766)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 1.4 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 0.3 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 1.1 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 11.9 GO:0042627 chylomicron(GO:0042627)
1.6 4.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.4 5.7 GO:0031673 H zone(GO:0031673)
1.4 20.7 GO:1902711 GABA-A receptor complex(GO:1902711)
1.0 8.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.0 3.0 GO:0098855 HCN channel complex(GO:0098855)
0.8 14.7 GO:0032433 filopodium tip(GO:0032433)
0.7 3.7 GO:0032437 cuticular plate(GO:0032437)
0.6 2.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.5 5.4 GO:0032426 stereocilium tip(GO:0032426)
0.5 2.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 9.5 GO:0032279 asymmetric synapse(GO:0032279)
0.4 1.8 GO:1990032 parallel fiber(GO:1990032)
0.4 10.5 GO:0071565 nBAF complex(GO:0071565)
0.4 3.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.4 8.9 GO:0034707 chloride channel complex(GO:0034707)
0.3 13.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 87.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 5.1 GO:0097440 apical dendrite(GO:0097440)
0.3 1.4 GO:0045298 tubulin complex(GO:0045298)
0.3 6.3 GO:0032590 dendrite membrane(GO:0032590)
0.3 2.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 12.5 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 0.9 GO:0033269 internode region of axon(GO:0033269)
0.2 12.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 32.4 GO:0030427 site of polarized growth(GO:0030427)
0.2 4.5 GO:0035371 microtubule plus-end(GO:0035371)
0.2 3.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 3.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.6 GO:0005869 dynactin complex(GO:0005869)
0.1 2.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 2.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 3.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0031252 cell leading edge(GO:0031252)
0.0 7.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 1.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 2.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 10.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.3 GO:0042641 actomyosin(GO:0042641)
0.0 1.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
2.4 9.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.7 15.4 GO:0008046 axon guidance receptor activity(GO:0008046)
1.3 8.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
1.2 10.5 GO:0030274 LIM domain binding(GO:0030274)
1.1 8.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.1 5.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.1 12.6 GO:0004890 GABA-A receptor activity(GO:0004890)
1.0 3.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.0 11.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.9 3.8 GO:0001847 opsonin receptor activity(GO:0001847)
0.9 6.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.8 5.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.7 3.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.7 4.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.7 12.5 GO:0030275 LRR domain binding(GO:0030275)
0.7 37.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.7 11.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 4.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.6 8.2 GO:0045499 chemorepellent activity(GO:0045499)
0.6 6.1 GO:0070700 BMP receptor binding(GO:0070700)
0.6 2.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.5 2.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 7.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 3.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.5 16.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.5 1.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.5 2.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 1.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 1.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 1.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 2.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.3 1.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 5.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.3 4.5 GO:0030955 potassium ion binding(GO:0030955)
0.3 1.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.3 1.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 3.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 2.1 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2 2.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 0.6 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 1.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 15.8 GO:0035254 glutamate receptor binding(GO:0035254)
0.2 9.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 1.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 3.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 2.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 1.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 5.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 3.7 GO:0030506 ankyrin binding(GO:0030506)
0.2 4.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 6.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 3.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 3.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.1 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1 11.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 1.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 1.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.0 GO:0015197 peptide transporter activity(GO:0015197)
0.1 5.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 4.1 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 3.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 4.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 11.7 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.9 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 8.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 4.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 4.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 2.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 4.7 GO:0003779 actin binding(GO:0003779)
0.0 7.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 21.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.3 8.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.2 7.1 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.2 3.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 5.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.2 12.5 PID_FGF_PATHWAY FGF signaling pathway
0.1 8.6 PID_LKB1_PATHWAY LKB1 signaling events
0.1 3.1 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 2.3 PID_MYC_PATHWAY C-MYC pathway
0.1 5.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.2 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.4 PID_CD40_PATHWAY CD40/CD40L signaling
0.1 3.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 1.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 6.5 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 0.7 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 1.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 3.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.4 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 8.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.4 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.6 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 WNT_SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 29.5 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.9 21.6 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.9 11.9 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 10.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 7.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.3 12.5 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.3 4.8 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.2 6.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 3.3 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 3.1 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.2 2.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 5.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 10.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.8 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 3.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 3.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.7 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 4.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.4 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.7 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.1 7.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.3 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 3.0 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 1.2 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.4 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation