Motif ID: Dbp

Z-value: 1.090


Transcription factors associated with Dbp:

Gene SymbolEntrez IDGene Name
Dbp ENSMUSG00000059824.4 Dbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbpmm10_v2_chr7_+_45705088_45705292-0.537.4e-07Click!


Activity profile for motif Dbp.

activity profile for motif Dbp


Sorted Z-values histogram for motif Dbp

Sorted Z-values for motif Dbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Dbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_123264076 19.616 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr10_+_85386813 12.786 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr8_+_68880491 11.947 ENSMUST00000015712.8
 Lpl
lipoprotein lipase
chr3_-_26133734 11.336 ENSMUST00000108308.3
ENSMUST00000075054.4
 Nlgn1

neuroligin 1

chr12_+_61523889 10.955 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr5_-_44799643 10.470 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chrX_-_72656135 9.322 ENSMUST00000055966.6
 Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr5_-_92042630 9.141 ENSMUST00000113140.1
ENSMUST00000113143.1
 Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr5_+_150259922 9.111 ENSMUST00000087204.5
 Fry
furry homolog (Drosophila)
chr1_+_66386968 8.939 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chrX_-_165327376 8.879 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chrX_-_43167817 8.791 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr10_-_64090265 8.642 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr6_-_91807424 8.315 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr16_+_7069825 7.815 ENSMUST00000056416.7
 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_28813125 7.792 ENSMUST00000029964.5
ENSMUST00000080934.4
 Epha7

Eph receptor A7

chr4_+_28813152 7.612 ENSMUST00000108194.2
ENSMUST00000108191.1
 Epha7

Eph receptor A7

chr6_-_91807318 7.487 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr10_+_99263224 7.396 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr14_-_93888732 7.216 ENSMUST00000068992.2
 Pcdh9
protocadherin 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 32.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.2 20.2 GO:1902993 positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2 19.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 17.0 GO:0060395 SMAD protein signal transduction(GO:0060395)
1.6 15.8 GO:0014824 artery smooth muscle contraction(GO:0014824)
2.6 15.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.7 12.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
4.2 12.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
3.0 11.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.3 11.3 GO:0071420 cellular response to histamine(GO:0071420)
0.2 11.3 GO:0034605 cellular response to heat(GO:0034605)
3.6 10.9 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.6 10.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 10.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 10.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
1.0 9.8 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
1.1 9.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.0 9.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.5 8.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 8.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 87.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 32.4 GO:0030427 site of polarized growth(GO:0030427)
1.4 20.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.8 14.7 GO:0032433 filopodium tip(GO:0032433)
0.3 13.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 12.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 12.5 GO:0044295 axonal growth cone(GO:0044295)
1.7 11.9 GO:0042627 chylomicron(GO:0042627)
0.4 10.5 GO:0071565 nBAF complex(GO:0071565)
0.0 10.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.5 9.5 GO:0032279 asymmetric synapse(GO:0032279)
1.0 8.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 8.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 7.8 GO:0005802 trans-Golgi network(GO:0005802)
0.3 6.3 GO:0032590 dendrite membrane(GO:0032590)
1.4 5.7 GO:0031673 H zone(GO:0031673)
0.5 5.4 GO:0032426 stereocilium tip(GO:0032426)
0.3 5.1 GO:0097440 apical dendrite(GO:0097440)
1.6 4.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 4.5 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 37.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.5 16.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 15.8 GO:0035254 glutamate receptor binding(GO:0035254)
1.7 15.4 GO:0008046 axon guidance receptor activity(GO:0008046)
1.1 12.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.7 12.5 GO:0030275 LRR domain binding(GO:0030275)
1.0 11.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 11.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 11.7 GO:0005516 calmodulin binding(GO:0005516)
0.7 11.3 GO:0042043 neurexin family protein binding(GO:0042043)
1.2 10.5 GO:0030274 LIM domain binding(GO:0030274)
2.4 9.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 9.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
3.0 8.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.1 8.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 8.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.6 8.2 GO:0045499 chemorepellent activity(GO:0045499)
1.3 8.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 7.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.5 7.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 21.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 12.5 PID_FGF_PATHWAY FGF signaling pathway
0.1 8.6 PID_LKB1_PATHWAY LKB1 signaling events
0.3 8.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 8.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 7.1 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 6.5 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 5.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 5.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 3.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 3.2 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.2 3.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 3.1 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 3.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 2.4 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 2.4 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.3 PID_MYC_PATHWAY C-MYC pathway
0.1 1.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 29.5 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.9 21.6 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3 12.5 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.9 11.9 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 10.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.6 10.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 7.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.5 7.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.2 6.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 5.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.3 4.8 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.2 4.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 4.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 3.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 3.4 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 3.3 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 3.1 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 3.0 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.2 2.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors