Motif ID: Dlx5_Dlx4

Z-value: 1.473

Transcription factors associated with Dlx5_Dlx4:

Gene SymbolEntrez IDGene Name
Dlx4 ENSMUSG00000020871.7 Dlx4
Dlx5 ENSMUSG00000029755.9 Dlx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dlx5mm10_v2_chr6_-_6882068_6882092-0.582.3e-08Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Dlx5_Dlx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 33.623 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr8_-_4779513 22.527 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chrM_+_9870 18.211 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_24612700 17.346 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr12_-_55014329 15.679 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chrM_+_10167 15.066 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr1_+_6487231 14.725 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr9_-_66514567 13.281 ENSMUST00000056890.8
Fbxl22
F-box and leucine-rich repeat protein 22
chr3_+_55782500 12.458 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr15_+_25773985 12.446 ENSMUST00000125667.1
Myo10
myosin X
chr9_-_16378231 12.231 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr9_+_65890237 11.581 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr1_+_139454747 11.574 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr2_-_121235689 11.046 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr9_-_36726374 10.961 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr17_-_59013264 10.657 ENSMUST00000174122.1
ENSMUST00000025065.5
Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr16_+_52031549 10.312 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr3_+_146121655 10.288 ENSMUST00000039450.4
Mcoln3
mucolipin 3
chr2_+_118814237 10.242 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr13_-_89742244 9.795 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr9_+_95857597 9.680 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related
chr2_+_118814195 9.633 ENSMUST00000110842.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr2_+_118813995 9.397 ENSMUST00000134661.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr2_+_172550991 9.096 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr8_+_45627946 9.021 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr5_-_84417359 8.929 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr8_-_57653023 8.864 ENSMUST00000034021.5
Galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr8_+_45628176 8.823 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr7_-_62464505 8.724 ENSMUST00000094339.2
Peg12
paternally expressed 12
chr14_-_100149764 8.650 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr4_+_8690399 8.508 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr8_+_45627709 8.179 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr4_+_126556935 7.892 ENSMUST00000048391.8
Clspn
claspin
chr13_-_89742490 7.731 ENSMUST00000109546.2
Vcan
versican
chr7_+_51621830 7.692 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr6_+_8948608 7.655 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr19_+_23723279 7.591 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr14_-_67715585 7.483 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr4_-_132075250 7.439 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chrX_-_60893430 7.244 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr4_+_110397661 7.168 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr8_+_116921735 7.146 ENSMUST00000034205.4
Cenpn
centromere protein N
chr2_+_119047116 7.104 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr17_+_29090969 7.000 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr4_+_109978004 6.793 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr10_-_128804353 6.699 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr10_-_81350389 6.632 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr10_-_76110956 6.555 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr9_-_15357692 6.488 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr2_-_180954620 6.420 ENSMUST00000139929.1
Nkain4
Na+/K+ transporting ATPase interacting 4
chr18_+_4920509 6.388 ENSMUST00000126977.1
Svil
supervillin
chr11_-_29515017 6.307 ENSMUST00000133103.1
ENSMUST00000039900.3
Prorsd1

prolyl-tRNA synthetase domain containing 1

chr5_+_138187485 6.214 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr13_+_104229366 5.994 ENSMUST00000022227.6
Cenpk
centromere protein K
chr1_-_172027269 5.979 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr10_-_81350191 5.976 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr1_-_5019342 5.960 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr2_+_165655237 5.895 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr4_+_126556994 5.878 ENSMUST00000147675.1
Clspn
claspin
chr8_+_3353415 5.846 ENSMUST00000098966.3
A430078G23Rik
RIKEN cDNA A430078G23 gene
chr6_+_34746368 5.755 ENSMUST00000142716.1
Cald1
caldesmon 1
chr2_-_26246707 5.720 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr10_-_81350305 5.691 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr9_-_21760275 5.673 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_-_19264959 5.602 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr4_-_110292719 5.591 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr4_+_43059028 5.569 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
Unc13b


unc-13 homolog B (C. elegans)


chr12_-_101028983 5.409 ENSMUST00000068411.3
ENSMUST00000085096.3
Ccdc88c

coiled-coil domain containing 88C

chr7_-_5413145 5.336 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chrM_+_11734 5.248 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chrM_-_14060 5.245 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr4_-_20778527 5.033 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr5_+_76588663 5.002 ENSMUST00000121979.1
Cep135
centrosomal protein 135
chr16_+_14906622 5.002 ENSMUST00000090277.1
Efcab1
EF hand calcium binding domain 1
chr17_+_34039437 4.894 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2



collagen, type XI, alpha 2



chr19_-_5875210 4.803 ENSMUST00000155227.1
Frmd8
FERM domain containing 8
chr5_-_44102032 4.781 ENSMUST00000171543.1
Prom1
prominin 1
chr10_-_8886033 4.693 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr2_-_79456750 4.691 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr8_-_116921408 4.669 ENSMUST00000078589.6
ENSMUST00000148235.1
Cmc2

COX assembly mitochondrial protein 2

chr8_-_116921365 4.607 ENSMUST00000128304.1
Cmc2
COX assembly mitochondrial protein 2
chr19_+_60144682 4.577 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chrM_+_3906 4.558 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr3_-_121171678 4.516 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr9_+_74953053 4.392 ENSMUST00000170846.1
Fam214a
family with sequence similarity 214, member A
chr12_+_52699297 4.295 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr4_-_41464816 4.284 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chrX_+_56454871 4.284 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr15_+_25742314 4.276 ENSMUST00000135981.1
Myo10
myosin X
chr16_-_16560046 4.221 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr17_-_35027909 4.220 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr4_+_43058939 4.197 ENSMUST00000079978.6
Unc13b
unc-13 homolog B (C. elegans)
chrM_+_7759 4.196 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr10_+_80264942 4.177 ENSMUST00000105362.1
ENSMUST00000105361.3
Dazap1

DAZ associated protein 1

chr17_+_21690766 4.168 ENSMUST00000097384.1
Gm10509
predicted gene 10509
chr2_+_110597298 4.108 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr13_-_24761440 4.105 ENSMUST00000176890.1
ENSMUST00000175689.1
Gmnn

geminin

chr8_-_122915987 4.036 ENSMUST00000098333.4
Ankrd11
ankyrin repeat domain 11
chr9_+_119063429 4.031 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr9_+_57998036 3.910 ENSMUST00000181289.1
Gm17322
predicted gene, 17322
chr10_+_26822560 3.882 ENSMUST00000135866.1
Arhgap18
Rho GTPase activating protein 18
chr2_-_168767136 3.855 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr3_-_51796516 3.820 ENSMUST00000118075.1
Maml3
mastermind like 3 (Drosophila)
chr16_+_15637844 3.740 ENSMUST00000023352.8
Prkdc
protein kinase, DNA activated, catalytic polypeptide
chr13_+_23575753 3.677 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr19_-_5875268 3.674 ENSMUST00000025728.6
Frmd8
FERM domain containing 8
chr1_+_161070767 3.628 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
Cenpl


centromere protein L


chr10_-_62814539 3.588 ENSMUST00000173087.1
ENSMUST00000174121.1
Tet1

tet methylcytosine dioxygenase 1

chr13_+_44729535 3.570 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr13_+_23555023 3.541 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr14_+_120275669 3.532 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr7_+_103550368 3.511 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr4_-_42661893 3.508 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr16_-_16560201 3.504 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr2_+_83724397 3.496 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr10_-_117148474 3.427 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr3_+_75557530 3.419 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr18_+_64340225 3.412 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr17_-_33685386 3.401 ENSMUST00000139302.1
ENSMUST00000087582.5
ENSMUST00000114385.2
Hnrnpm


heterogeneous nuclear ribonucleoprotein M


chr2_+_125068118 3.393 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chrX_+_159303266 3.351 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr14_-_47276790 3.285 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
Wdhd1


WD repeat and HMG-box DNA binding protein 1


chr16_-_16599978 3.262 ENSMUST00000162671.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr10_-_92162753 3.259 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr6_+_37870786 3.216 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr10_+_50592669 3.199 ENSMUST00000035606.8
Ascc3
activating signal cointegrator 1 complex subunit 3
chrM_+_14138 3.174 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr4_-_20778852 3.160 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr5_-_112228934 3.159 ENSMUST00000181535.2
Miat
myocardial infarction associated transcript (non-protein coding)
chr14_+_67716262 3.141 ENSMUST00000150768.1
Kctd9
potassium channel tetramerisation domain containing 9
chr9_+_27299205 3.103 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr13_-_3918157 3.102 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr6_-_120357440 3.101 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr13_-_34963788 3.101 ENSMUST00000164155.1
ENSMUST00000021853.5
Eci3

enoyl-Coenzyme A delta isomerase 3

chr7_+_89404356 3.078 ENSMUST00000058755.3
Fzd4
frizzled homolog 4 (Drosophila)
chr14_+_7817957 3.047 ENSMUST00000052678.8
Flnb
filamin, beta
chr5_-_112228900 3.008 ENSMUST00000182509.1
Miat
myocardial infarction associated transcript (non-protein coding)
chr14_+_47298260 2.963 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr12_+_116275386 2.961 ENSMUST00000090195.4
Gm11027
predicted gene 11027
chr9_-_53248106 2.958 ENSMUST00000065630.6
Ddx10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr6_-_149101506 2.939 ENSMUST00000127727.1
Dennd5b
DENN/MADD domain containing 5B
chr9_+_13621646 2.902 ENSMUST00000034401.8
Maml2
mastermind like 2 (Drosophila)
chr9_+_104063678 2.879 ENSMUST00000047799.5
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr4_+_62583568 2.861 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr14_+_67716095 2.857 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr1_+_174501796 2.857 ENSMUST00000030039.7
Fmn2
formin 2
chr7_+_19508712 2.848 ENSMUST00000002112.8
ENSMUST00000108455.1
Trappc6a

trafficking protein particle complex 6A

chr2_-_37703845 2.844 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr13_-_54565299 2.844 ENSMUST00000153065.1
ENSMUST00000126295.1
ENSMUST00000143144.1
ENSMUST00000132136.1
4833439L19Rik



RIKEN cDNA 4833439L19 gene



chr4_-_132510493 2.805 ENSMUST00000030724.8
Sesn2
sestrin 2
chr7_+_29983948 2.753 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr2_+_176711933 2.748 ENSMUST00000108983.2
Gm14305
predicted gene 14305
chr15_+_7129557 2.747 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr5_-_106926245 2.725 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr4_+_126103940 2.721 ENSMUST00000116286.2
ENSMUST00000094761.4
ENSMUST00000139524.1
Stk40


serine/threonine kinase 40


chr7_-_102099932 2.720 ENSMUST00000106934.1
Art5
ADP-ribosyltransferase 5
chr12_-_111813834 2.710 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr4_-_96553617 2.708 ENSMUST00000030303.5
Cyp2j6
cytochrome P450, family 2, subfamily j, polypeptide 6
chr7_+_38183217 2.698 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chr11_+_120491840 2.693 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr15_-_35155750 2.655 ENSMUST00000067033.7
ENSMUST00000018476.7
Stk3

serine/threonine kinase 3

chr16_-_10543028 2.653 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr7_-_25477607 2.606 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
Ceacam1


carcinoembryonic antigen-related cell adhesion molecule 1


chr1_+_15312452 2.591 ENSMUST00000171715.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr6_-_50456085 2.588 ENSMUST00000146341.1
ENSMUST00000071728.4
Osbpl3

oxysterol binding protein-like 3

chrX_-_75578188 2.586 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr13_+_44121167 2.568 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr17_-_31277327 2.542 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr5_+_9100681 2.523 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chrX_+_103356464 2.511 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr6_-_149101674 2.509 ENSMUST00000111557.1
Dennd5b
DENN/MADD domain containing 5B
chr16_+_87454976 2.483 ENSMUST00000119504.1
ENSMUST00000131356.1
Usp16

ubiquitin specific peptidase 16

chr19_-_53464721 2.444 ENSMUST00000180489.1
5830416P10Rik
RIKEN cDNA 5830416P10 gene
chr7_+_128744870 2.443 ENSMUST00000042942.8
Sec23ip
Sec23 interacting protein
chr18_+_32067729 2.420 ENSMUST00000025243.3
Iws1
IWS1 homolog (S. cerevisiae)
chr9_-_65885024 2.404 ENSMUST00000122410.1
ENSMUST00000117083.1
Trip4

thyroid hormone receptor interactor 4

chrX_+_20364481 2.387 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
Rp2h


retinitis pigmentosa 2 homolog (human)


chr12_+_80790532 2.376 ENSMUST00000068519.5
4933426M11Rik
RIKEN cDNA 4933426M11 gene
chr16_+_34690548 2.376 ENSMUST00000023532.6
Ccdc14
coiled-coil domain containing 14
chr12_+_38781093 2.364 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr4_-_123664725 2.361 ENSMUST00000147030.1
Macf1
microtubule-actin crosslinking factor 1
chr3_+_88629442 2.331 ENSMUST00000176316.1
ENSMUST00000176879.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr3_+_88629499 2.329 ENSMUST00000175745.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr2_+_69897255 2.324 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr19_-_12796108 2.317 ENSMUST00000038627.8
Zfp91
zinc finger protein 91
chr13_+_21717626 2.284 ENSMUST00000091754.2
Hist1h3h
histone cluster 1, H3h
chr12_+_38780284 2.282 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr10_+_21377290 2.274 ENSMUST00000042699.7
ENSMUST00000159163.1
Aldh8a1

aldehyde dehydrogenase 8 family, member A1

chr6_-_42645254 2.262 ENSMUST00000031879.3
Fam115c
family with sequence similarity 115, member C
chr2_-_170131156 2.256 ENSMUST00000063710.6
Zfp217
zinc finger protein 217
chr13_-_21716143 2.247 ENSMUST00000091756.1
Hist1h2bl
histone cluster 1, H2bl
chr11_+_106216926 2.240 ENSMUST00000021046.5
Ddx42
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chr17_-_36020525 2.238 ENSMUST00000174063.1
ENSMUST00000113760.3
H2-T24

histocompatibility 2, T region locus 24

chr13_-_12258093 2.223 ENSMUST00000099856.4
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr2_-_161109017 2.211 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr7_-_143460989 2.197 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr14_+_79515618 2.188 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr14_+_56668242 2.186 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr2_-_86347764 2.167 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr11_+_71749914 2.155 ENSMUST00000150531.1
Wscd1
WSC domain containing 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 36.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
3.4 10.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
3.2 9.7 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
3.0 9.1 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
2.8 8.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
2.4 9.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
2.1 10.7 GO:0051661 maintenance of centrosome location(GO:0051661)
2.0 6.0 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.9 7.7 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
1.8 7.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
1.8 31.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.6 4.9 GO:0060023 soft palate development(GO:0060023)
1.6 4.8 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
1.6 11.0 GO:0030035 microspike assembly(GO:0030035)
1.6 11.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
1.6 4.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.6 4.7 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.5 4.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
1.5 5.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.4 13.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.4 1.4 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
1.3 6.6 GO:1904659 glucose transmembrane transport(GO:1904659)
1.3 17.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.3 5.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
1.2 14.7 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.2 3.5 GO:0038044 negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044)
1.1 4.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
1.1 18.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
1.0 4.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
1.0 3.1 GO:0061300 cerebellum vasculature development(GO:0061300)
1.0 2.9 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.9 10.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.9 2.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.9 2.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.9 1.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.9 2.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.9 8.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.9 7.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.8 3.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.8 2.5 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.8 3.3 GO:0070829 heterochromatin maintenance(GO:0070829)
0.8 3.2 GO:0033762 response to glucagon(GO:0033762)
0.8 10.7 GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.7 6.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.7 5.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.7 11.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.7 2.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.7 3.6 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.7 2.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.7 2.7 GO:0015744 succinate transport(GO:0015744)
0.7 2.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6 3.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.6 25.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.6 1.8 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.6 1.8 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.6 4.7 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.6 1.7 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.6 2.8 GO:1903232 melanosome assembly(GO:1903232)
0.6 2.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.6 26.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.6 0.6 GO:0006404 RNA import into nucleus(GO:0006404)
0.5 3.3 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.5 3.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.5 3.5 GO:0016584 nucleosome positioning(GO:0016584)
0.5 1.5 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.5 1.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.5 3.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.5 1.4 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.4 3.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.4 0.9 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.4 12.2 GO:0010842 retina layer formation(GO:0010842)
0.4 6.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 5.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.4 2.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.4 1.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4 1.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.4 24.2 GO:0008347 glial cell migration(GO:0008347)
0.4 2.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.4 1.5 GO:0015825 L-serine transport(GO:0015825)
0.4 7.2 GO:0007530 sex determination(GO:0007530)
0.4 3.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.4 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.3 1.0 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.3 2.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.3 5.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 0.9 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.3 1.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.3 1.5 GO:0018158 protein oxidation(GO:0018158)
0.3 2.7 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3 0.6 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.3 8.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.7 GO:0090527 actin filament reorganization(GO:0090527)
0.3 0.6 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.3 0.8 GO:0045006 DNA deamination(GO:0045006)
0.3 0.8 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.3 0.8 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.3 1.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.3 20.1 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.3 10.3 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.2 1.0 GO:0030647 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.2 2.7 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 8.7 GO:0000578 embryonic axis specification(GO:0000578)
0.2 0.7 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.2 1.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 2.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 0.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 0.7 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 0.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 1.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 1.6 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.2 7.1 GO:0034508 centromere complex assembly(GO:0034508)
0.2 2.4 GO:0001675 acrosome assembly(GO:0001675)
0.2 3.1 GO:0051451 myoblast migration(GO:0051451)
0.2 2.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 3.0 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.6 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.2 14.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 1.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 1.4 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.2 1.5 GO:0032328 alanine transport(GO:0032328)
0.2 1.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.2 0.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 1.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 11.0 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.2 1.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.2 0.9 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 4.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 1.7 GO:0009404 toxin metabolic process(GO:0009404)
0.2 1.9 GO:0060746 parental behavior(GO:0060746)
0.2 2.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 7.7 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.2 1.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 1.5 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.2 2.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 1.4 GO:0009301 snRNA transcription(GO:0009301)
0.2 2.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 1.7 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.6 GO:0080009 mRNA methylation(GO:0080009)
0.1 5.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 3.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 5.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 2.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.2 GO:0007096 regulation of exit from mitosis(GO:0007096) uterus development(GO:0060065)
0.1 1.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 6.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 13.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 4.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:2000543 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) positive regulation of gastrulation(GO:2000543)
0.1 15.3 GO:0006338 chromatin remodeling(GO:0006338)
0.1 2.7 GO:0003016 respiratory system process(GO:0003016)
0.1 2.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 2.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 2.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 3.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 2.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 2.7 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 3.7 GO:0051693 actin filament capping(GO:0051693)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 4.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 4.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 2.9 GO:0031648 protein destabilization(GO:0031648)
0.1 1.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579) regulation of mitochondrial depolarization(GO:0051900)
0.1 0.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 3.4 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 2.0 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 2.5 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.1 GO:0070827 chromatin maintenance(GO:0070827)
0.1 1.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 3.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 1.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.3 GO:0006265 DNA topological change(GO:0006265)
0.1 0.5 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 1.6 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.0 3.4 GO:1904591 positive regulation of protein import(GO:1904591)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.6 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 1.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.1 GO:0051647 nucleus localization(GO:0051647)
0.0 0.1 GO:1990000 amyloid fibril formation(GO:1990000)
0.0 1.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 2.1 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.9 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.7 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 1.2 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.4 GO:0006907 pinocytosis(GO:0006907)
0.0 3.5 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.9 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 4.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.7 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 2.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.6 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.3 GO:0010667 negative regulation of striated muscle cell apoptotic process(GO:0010664) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.4 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 1.2 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.5 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.6 GO:0007569 cell aging(GO:0007569)
0.0 0.0 GO:0000389 generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.0 3.2 GO:0051260 protein homooligomerization(GO:0051260)
0.0 4.9 GO:0010498 proteasomal protein catabolic process(GO:0010498)
0.0 0.1 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.0 0.5 GO:0002377 immunoglobulin production(GO:0002377)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 18.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
3.9 15.7 GO:0008623 CHRAC(GO:0008623)
2.3 7.0 GO:0070557 PCNA-p21 complex(GO:0070557)
2.3 11.6 GO:0036449 microtubule minus-end(GO:0036449)
1.6 9.8 GO:0044305 calyx of Held(GO:0044305)
1.6 4.8 GO:0071914 prominosome(GO:0071914)
1.5 6.0 GO:0060187 cell pole(GO:0060187)
1.2 3.5 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.9 5.7 GO:0031262 Ndc80 complex(GO:0031262)
0.9 31.6 GO:1990752 microtubule end(GO:1990752)
0.9 3.4 GO:0031983 vesicle lumen(GO:0031983)
0.7 1.4 GO:0016600 flotillin complex(GO:0016600)
0.7 3.3 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.6 5.8 GO:0030478 actin cap(GO:0030478)
0.6 52.6 GO:0070469 respiratory chain(GO:0070469)
0.6 3.7 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.5 2.1 GO:0031673 H zone(GO:0031673)
0.5 2.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.5 6.5 GO:0042788 polysomal ribosome(GO:0042788)
0.5 3.2 GO:0033503 HULC complex(GO:0033503)
0.5 3.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.4 3.4 GO:0042382 paraspeckles(GO:0042382)
0.4 1.3 GO:0034657 GID complex(GO:0034657)
0.4 1.7 GO:1990032 parallel fiber(GO:1990032)
0.4 9.7 GO:0001741 XY body(GO:0001741)
0.3 2.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.3 11.0 GO:0035861 site of double-strand break(GO:0035861)
0.3 7.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 2.5 GO:0072687 meiotic spindle(GO:0072687)
0.3 2.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 9.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 17.4 GO:0016459 myosin complex(GO:0016459)
0.3 1.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 1.4 GO:0030891 VCB complex(GO:0030891)
0.3 3.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.5 GO:0097413 Lewy body(GO:0097413)
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 4.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 4.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 1.4 GO:0070187 telosome(GO:0070187)
0.2 1.4 GO:0097422 tubular endosome(GO:0097422)
0.2 14.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 20.6 GO:0005814 centriole(GO:0005814)
0.2 2.8 GO:0030008 TRAPP complex(GO:0030008)
0.2 1.4 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 2.3 GO:0032797 SMN complex(GO:0032797)
0.2 11.2 GO:0005657 replication fork(GO:0005657)
0.2 2.6 GO:0042101 T cell receptor complex(GO:0042101)
0.2 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 3.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 0.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 1.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 15.6 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.1 GO:0051286 cell tip(GO:0051286)
0.1 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 15.8 GO:0000776 kinetochore(GO:0000776)
0.1 2.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 6.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 4.7 GO:0002102 podosome(GO:0002102)
0.1 2.4 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 2.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 8.4 GO:0030175 filopodium(GO:0030175)
0.1 1.0 GO:0042571 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.1 1.3 GO:1990391 DNA repair complex(GO:1990391)
0.1 7.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.0 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 5.8 GO:0000792 heterochromatin(GO:0000792)
0.1 1.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.2 GO:0031519 PcG protein complex(GO:0031519)
0.1 2.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.7 GO:0005687 U4 snRNP(GO:0005687)
0.1 4.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.1 GO:0005844 polysome(GO:0005844)
0.1 2.9 GO:0005902 microvillus(GO:0005902)
0.1 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.9 GO:0005938 cell cortex(GO:0005938)
0.0 2.5 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 21.9 GO:0005694 chromosome(GO:0005694)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 2.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 9.6 GO:0016604 nuclear body(GO:0016604)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 28.9 GO:0005654 nucleoplasm(GO:0005654)
0.0 1.2 GO:0005930 axoneme(GO:0005930)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.7 GO:0005813 centrosome(GO:0005813)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
3.3 9.8 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
2.7 10.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
2.3 7.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
2.3 13.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.8 11.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.6 9.7 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
1.6 46.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.2 3.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
1.1 8.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
1.0 17.5 GO:0005540 hyaluronic acid binding(GO:0005540)
1.0 2.9 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.9 5.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.9 2.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.9 4.6 GO:0070330 aromatase activity(GO:0070330)
0.9 2.7 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.9 19.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.9 2.7 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.7 3.5 GO:0038132 neuregulin binding(GO:0038132)
0.7 4.1 GO:0002135 CTP binding(GO:0002135)
0.7 3.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.6 3.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.6 3.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.6 4.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 1.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.5 4.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 22.5 GO:0042169 SH2 domain binding(GO:0042169)
0.5 8.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 3.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 2.8 GO:0070728 leucine binding(GO:0070728)
0.5 3.2 GO:0034056 estrogen response element binding(GO:0034056)
0.5 3.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.4 2.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.4 6.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.4 3.4 GO:1990405 protein antigen binding(GO:1990405)
0.4 5.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.4 2.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.4 2.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.4 2.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 0.9 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.3 4.3 GO:0043495 protein anchor(GO:0043495)
0.3 10.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 1.7 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 16.7 GO:0030507 spectrin binding(GO:0030507)
0.3 1.4 GO:0043532 angiostatin binding(GO:0043532)
0.3 0.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 11.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 2.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 1.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 7.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 6.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 6.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 1.4 GO:0034452 dynactin binding(GO:0034452)
0.2 1.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 4.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 0.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 2.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 5.6 GO:0017091 AU-rich element binding(GO:0017091)
0.2 2.0 GO:0017166 vinculin binding(GO:0017166)
0.2 1.0 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.2 14.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 1.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 4.8 GO:0042805 actinin binding(GO:0042805)
0.1 0.4 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 1.0 GO:0071253 connexin binding(GO:0071253)
0.1 3.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 2.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 9.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 10.0 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 5.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 5.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.8 GO:0005123 death receptor binding(GO:0005123)
0.1 5.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 4.2 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 2.2 GO:0051787 misfolded protein binding(GO:0051787)
0.1 2.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 4.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.6 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 2.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 16.2 GO:0001047 core promoter binding(GO:0001047)
0.1 3.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 3.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 3.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 2.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 4.3 GO:0003777 microtubule motor activity(GO:0003777)
0.1 11.0 GO:0042393 histone binding(GO:0042393)
0.1 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.3 GO:0015485 cholesterol binding(GO:0015485)
0.1 49.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 1.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 13.9 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 7.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 3.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 5.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 3.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 3.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 6.3 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 3.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 2.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.1 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 3.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.8 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 18.0 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 16.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.5 9.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.4 4.3 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 19.4 PID_PLK1_PATHWAY PLK1 signaling events
0.3 16.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.3 8.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 9.4 PID_CD40_PATHWAY CD40/CD40L signaling
0.2 8.8 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.2 3.5 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.2 6.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 5.4 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.2 6.0 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.2 1.5 PID_IL5_PATHWAY IL5-mediated signaling events
0.2 6.2 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 3.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.9 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 1.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.7 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 1.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 2.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 1.9 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.0 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 2.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.6 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 2.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 0.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 4.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 0.7 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.6 PID_ARF6_PATHWAY Arf6 signaling events
0.1 0.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 2.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 2.4 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 2.6 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 3.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.8 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.0 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 2.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 20.6 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.2 16.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.5 11.3 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 6.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.4 20.0 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 3.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 3.5 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.3 4.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.3 3.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 6.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 1.4 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.3 10.2 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 20.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.3 6.1 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 3.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 8.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.2 6.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 1.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 4.2 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.2 4.8 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 1.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.4 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.2 18.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 12.6 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 3.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 2.6 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 3.7 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.1 1.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 0.9 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 0.8 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 5.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.4 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 1.4 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.2 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.7 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.8 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.7 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 3.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules