Motif ID: E2f1

Z-value: 2.598


Transcription factors associated with E2f1:

Gene SymbolEntrez IDGene Name
E2f1 ENSMUSG00000027490.11 E2f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f1mm10_v2_chr2_-_154569720_1545697990.869.0e-24Click!


Activity profile for motif E2f1.

activity profile for motif E2f1


Sorted Z-values histogram for motif E2f1

Sorted Z-values for motif E2f1



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_34372004 37.812 ENSMUST00000113132.2
ENSMUST00000040638.8
Pbx3

pre B cell leukemia homeobox 3

chrX_-_60893430 37.130 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr5_+_45669907 31.365 ENSMUST00000117396.1
Ncapg
non-SMC condensin I complex, subunit G
chr4_+_126556935 30.261 ENSMUST00000048391.8
Clspn
claspin
chr17_+_56303396 27.439 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr4_-_59549314 26.185 ENSMUST00000148331.2
ENSMUST00000030076.5
Ptbp3

polypyrimidine tract binding protein 3

chr5_-_106458440 24.108 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr15_+_55557399 23.449 ENSMUST00000022998.7
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr15_-_78773452 23.428 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_+_56303321 23.425 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr4_-_59549243 23.221 ENSMUST00000173699.1
ENSMUST00000173884.1
ENSMUST00000102883.4
ENSMUST00000174586.1
Ptbp3



polypyrimidine tract binding protein 3



chr9_+_65890237 22.495 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr14_-_52020698 21.422 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chr10_-_128704978 21.162 ENSMUST00000026416.7
ENSMUST00000026415.7
Cdk2

cyclin-dependent kinase 2

chr9_-_61946768 21.037 ENSMUST00000034815.7
Kif23
kinesin family member 23
chr2_+_163054682 20.482 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr4_+_115000156 20.480 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr4_+_126556994 20.323 ENSMUST00000147675.1
Clspn
claspin
chr5_+_123749696 19.495 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr14_-_47276790 19.425 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
Wdhd1


WD repeat and HMG-box DNA binding protein 1


chr15_+_55557575 19.293 ENSMUST00000170046.1
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr2_+_172550761 18.695 ENSMUST00000099058.3
Tfap2c
transcription factor AP-2, gamma
chr4_+_8691303 18.572 ENSMUST00000051558.3
Chd7
chromodomain helicase DNA binding protein 7
chr12_+_24708241 18.142 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr7_+_102441685 17.678 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr13_-_47106176 17.544 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chrX_+_35888808 17.333 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr11_-_69948145 17.300 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr1_-_20820213 17.276 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr13_-_103920508 17.239 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2ip


Erbb2 interacting protein


chr15_-_58135047 17.010 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chr11_+_98907801 16.820 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr4_+_115000174 16.740 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr1_-_138848576 16.049 ENSMUST00000112030.2
Lhx9
LIM homeobox protein 9
chr13_-_47105790 15.986 ENSMUST00000129352.1
Dek
DEK oncogene (DNA binding)
chr12_+_116405397 15.377 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr11_+_80300866 15.331 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr4_-_91371946 14.765 ENSMUST00000176362.1
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr6_+_134929118 14.722 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr6_+_134929089 14.653 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr7_+_45215753 14.532 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr6_-_39206782 14.491 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr11_-_101551837 14.198 ENSMUST00000017290.4
Brca1
breast cancer 1
chr4_+_52439235 14.167 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
Smc2


structural maintenance of chromosomes 2


chr14_-_21989475 14.159 ENSMUST00000043409.7
Zfp503
zinc finger protein 503
chr17_-_35516780 13.945 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr14_+_31217850 13.905 ENSMUST00000090180.2
Sema3g
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr7_+_13278778 13.808 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr17_-_71526819 13.440 ENSMUST00000024851.9
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr12_+_69168808 13.333 ENSMUST00000110621.1
Lrr1
leucine rich repeat protein 1
chr11_+_119022962 13.098 ENSMUST00000026662.7
Cbx2
chromobox 2
chr6_+_113531675 13.047 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr5_-_44101668 12.871 ENSMUST00000087441.4
ENSMUST00000074113.6
Prom1

prominin 1

chr6_+_47454320 12.802 ENSMUST00000031697.8
Cul1
cullin 1
chr2_+_52072823 12.743 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr14_-_67715585 12.717 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr7_+_110122299 12.441 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr17_-_56830916 12.375 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chrX_-_111463149 12.283 ENSMUST00000096348.3
ENSMUST00000113428.2
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr14_+_47276910 12.243 ENSMUST00000065562.4
Socs4
suppressor of cytokine signaling 4
chr2_+_35109482 12.206 ENSMUST00000028235.4
ENSMUST00000156933.1
ENSMUST00000028237.8
Cep110


centrosomal protein 110


chr13_-_100775844 12.203 ENSMUST00000075550.3
Cenph
centromere protein H
chr4_-_91372028 12.113 ENSMUST00000107110.1
ENSMUST00000008633.8
ENSMUST00000107118.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr17_+_43667389 12.075 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr9_-_97018823 11.967 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr3_+_40800013 11.811 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr15_-_98004695 11.809 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr18_+_4921662 11.760 ENSMUST00000143254.1
Svil
supervillin
chr6_+_47453874 11.751 ENSMUST00000146200.1
Cul1
cullin 1
chr8_+_71406003 11.626 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr5_+_118027743 11.589 ENSMUST00000031304.7
Tesc
tescalcin
chr15_-_82212796 11.326 ENSMUST00000179269.1
AI848285
expressed sequence AI848285
chr7_-_102250086 11.260 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr2_+_119618717 11.209 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr1_-_191575534 11.200 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr4_+_24496434 11.130 ENSMUST00000108222.2
ENSMUST00000138567.2
ENSMUST00000050446.6
Mms22l


MMS22-like, DNA repair protein


chr15_-_98004634 11.106 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr11_-_84525514 11.099 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr12_+_24708984 11.096 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr5_+_65764073 11.009 ENSMUST00000138239.1
ENSMUST00000087264.3
N4bp2

NEDD4 binding protein 2

chr6_+_146888481 10.950 ENSMUST00000016631.7
ENSMUST00000111623.2
Ppfibp1

PTPRF interacting protein, binding protein 1 (liprin beta 1)

chr11_-_34833631 10.752 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr3_+_40800054 10.687 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr6_-_126939524 10.669 ENSMUST00000144954.1
ENSMUST00000112221.1
ENSMUST00000112220.1
Rad51ap1


RAD51 associated protein 1


chr4_-_133968611 10.649 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr13_+_113035111 10.628 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr15_+_75862310 10.596 ENSMUST00000023238.4
Gsdmd
gasdermin D
chr10_-_120476469 10.511 ENSMUST00000072777.7
ENSMUST00000159699.1
Hmga2

high mobility group AT-hook 2

chr10_-_80433615 10.496 ENSMUST00000105346.3
ENSMUST00000020377.6
ENSMUST00000105340.1
ENSMUST00000020379.6
ENSMUST00000105344.1
ENSMUST00000105342.1
ENSMUST00000105345.3
ENSMUST00000105343.1
Tcf3







transcription factor 3







chr5_+_115845229 10.361 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr7_-_127218390 10.352 ENSMUST00000142356.1
ENSMUST00000106314.1
Sept1

septin 1

chr8_-_122678072 10.338 ENSMUST00000006525.7
ENSMUST00000064674.6
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr14_-_73325773 10.201 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr4_-_41697040 10.199 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr17_+_21707682 10.165 ENSMUST00000073312.6
Zfp760
zinc finger protein 760
chrX_-_111463103 10.085 ENSMUST00000137712.2
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr4_+_11558914 10.053 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr2_-_18048784 10.035 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr2_-_157204483 9.973 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr19_-_9899450 9.920 ENSMUST00000025562.7
Incenp
inner centromere protein
chr7_-_141443989 9.904 ENSMUST00000026580.5
Lrdd
leucine-rich and death domain containing
chr1_+_172312367 9.898 ENSMUST00000039506.9
Igsf8
immunoglobulin superfamily, member 8
chr1_+_61638819 9.881 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr9_-_36726374 9.851 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr2_+_103566304 9.847 ENSMUST00000076212.3
Abtb2
ankyrin repeat and BTB (POZ) domain containing 2
chr8_-_53638945 9.843 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr11_+_79993062 9.802 ENSMUST00000017692.8
ENSMUST00000163272.1
Suz12

suppressor of zeste 12 homolog (Drosophila)

chr7_-_48881032 9.799 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr7_+_82867327 9.669 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr19_+_41482632 9.553 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr8_-_80739497 9.391 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr16_-_18811615 9.361 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr7_-_127218303 9.310 ENSMUST00000106313.1
Sept1
septin 1
chr16_+_37011758 9.255 ENSMUST00000071452.5
ENSMUST00000054034.6
Polq

polymerase (DNA directed), theta

chr9_+_119402444 9.220 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr9_-_82975475 9.039 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr4_-_135272798 9.027 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr13_-_78197815 8.947 ENSMUST00000127137.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr4_-_132422394 8.765 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr18_-_67641329 8.714 ENSMUST00000097542.2
Cep76
centrosomal protein 76
chr2_+_158768083 8.626 ENSMUST00000029183.2
Fam83d
family with sequence similarity 83, member D
chr9_-_56928350 8.597 ENSMUST00000050916.5
Snx33
sorting nexin 33
chr16_+_21204755 8.568 ENSMUST00000006112.6
Ephb3
Eph receptor B3
chr7_-_48881596 8.512 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr12_-_98901478 8.465 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr4_-_132422484 8.427 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr2_+_109280738 8.413 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr10_+_128232065 8.372 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr1_+_172481788 8.295 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr13_-_64153194 8.168 ENSMUST00000059817.4
ENSMUST00000117241.1
Zfp367

zinc finger protein 367

chr7_-_89980935 8.164 ENSMUST00000107234.1
Eed
embryonic ectoderm development
chr11_+_21239279 8.135 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54

vacuolar protein sorting 54 (yeast)

chr2_+_105668888 8.107 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr2_-_180889660 8.092 ENSMUST00000137629.1
Gm14342
predicted gene 14342
chr11_-_116335384 8.088 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr13_-_55329723 8.008 ENSMUST00000021941.7
Mxd3
Max dimerization protein 3
chr11_+_49203465 7.989 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr11_+_84525669 7.983 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr8_+_95633500 7.951 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr14_+_50955992 7.884 ENSMUST00000095925.4
Pnp2
purine-nucleoside phosphorylase 2
chr1_+_172482199 7.864 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr4_-_133967893 7.769 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr2_+_154436437 7.753 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr15_-_55090422 7.752 ENSMUST00000110231.1
ENSMUST00000023059.6
Dscc1

defective in sister chromatid cohesion 1 homolog (S. cerevisiae)

chr12_+_16894894 7.733 ENSMUST00000020904.6
Rock2
Rho-associated coiled-coil containing protein kinase 2
chr6_-_47594967 7.730 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
Ezh2


enhancer of zeste homolog 2 (Drosophila)


chr4_-_133967235 7.724 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr9_-_27155418 7.712 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr17_-_40935047 7.711 ENSMUST00000087114.3
Cenpq
centromere protein Q
chr13_-_21750505 7.680 ENSMUST00000102983.1
Hist1h4k
histone cluster 1, H4k
chr13_-_23761223 7.645 ENSMUST00000102964.2
Hist1h4a
histone cluster 1, H4a
chr5_-_37336870 7.605 ENSMUST00000031005.4
Evc
Ellis van Creveld gene syndrome
chr1_+_191063001 7.598 ENSMUST00000076952.5
ENSMUST00000139340.1
ENSMUST00000078259.6
Nsl1


NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)


chr11_+_49203285 7.589 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr8_-_111300222 7.580 ENSMUST00000038739.4
Rfwd3
ring finger and WD repeat domain 3
chr4_+_136469755 7.485 ENSMUST00000170102.1
ENSMUST00000105849.2
ENSMUST00000129230.2
Luzp1


leucine zipper protein 1


chr16_-_36784784 7.473 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chrX_+_170009659 7.442 ENSMUST00000179760.1
Gm21887
predicted gene, 21887
chr19_+_38931008 7.422 ENSMUST00000145051.1
Hells
helicase, lymphoid specific
chr4_+_62965560 7.397 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr2_-_125625065 7.386 ENSMUST00000089776.2
Cep152
centrosomal protein 152
chr16_-_16146771 7.384 ENSMUST00000040248.7
Spidr
scaffolding protein involved i DNA repair
chr4_-_116123618 7.384 ENSMUST00000102704.3
ENSMUST00000102705.3
Rad54l

RAD54 like (S. cerevisiae)

chrX_+_71556874 7.348 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chrX_+_18162575 7.321 ENSMUST00000044484.6
ENSMUST00000052368.8
Kdm6a

lysine (K)-specific demethylase 6A

chr1_-_190169399 7.312 ENSMUST00000010319.7
Prox1
prospero-related homeobox 1
chr10_-_92722356 7.306 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr8_-_33385470 7.272 ENSMUST00000033991.6
ENSMUST00000033990.5
Wrn

Werner syndrome homolog (human)

chr3_+_89229046 7.235 ENSMUST00000041142.3
Muc1
mucin 1, transmembrane
chr3_+_127553462 7.224 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr3_-_100969644 7.214 ENSMUST00000076941.5
Ttf2
transcription termination factor, RNA polymerase II
chr1_-_181842334 7.173 ENSMUST00000005003.6
Lbr
lamin B receptor
chr9_+_13246982 7.157 ENSMUST00000110583.2
ENSMUST00000169961.1
Ccdc82

coiled-coil domain containing 82

chr11_+_84525647 7.138 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chrY_+_90784738 7.135 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr11_-_77078404 7.115 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr4_-_133967296 7.112 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr14_+_51984826 7.042 ENSMUST00000093813.5
Arhgef40
Rho guanine nucleotide exchange factor (GEF) 40
chr2_-_38287347 7.032 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr19_+_36409719 7.029 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr14_+_51984857 7.020 ENSMUST00000100639.4
ENSMUST00000182909.1
ENSMUST00000182760.1
ENSMUST00000182061.1
ENSMUST00000182193.1
Arhgef40




Rho guanine nucleotide exchange factor (GEF) 40




chr8_+_87473116 7.001 ENSMUST00000182650.1
ENSMUST00000182758.1
ENSMUST00000181898.1
Gm2694


predicted gene 2694


chr2_-_18048347 6.946 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr10_-_117376922 6.883 ENSMUST00000177145.1
ENSMUST00000176670.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr12_-_54999102 6.864 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr2_+_105668935 6.854 ENSMUST00000142772.1
Pax6
paired box gene 6
chr13_-_29984219 6.847 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr17_+_56304313 6.823 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr3_+_40800778 6.788 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr5_-_65697856 6.781 ENSMUST00000031104.6
Pds5a
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr11_-_106272927 6.694 ENSMUST00000021052.9
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr12_-_4233958 6.683 ENSMUST00000111169.3
ENSMUST00000020981.5
Cenpo

centromere protein O

chr14_+_26579535 6.679 ENSMUST00000037585.7
Dennd6a
DENN/MADD domain containing 6A
chr19_+_38930909 6.672 ENSMUST00000025965.5
Hells
helicase, lymphoid specific
chr16_-_36784924 6.658 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr12_+_110279228 6.573 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr9_-_72111651 6.553 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr9_+_123478693 6.536 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chr2_+_18064564 6.522 ENSMUST00000114671.1
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr5_+_120431770 6.515 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 53.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
9.3 46.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
8.1 24.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
7.0 21.0 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
6.2 18.7 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
6.2 18.6 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
6.0 24.0 GO:2000768 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
5.9 41.2 GO:0098535 de novo centriole assembly(GO:0098535)
5.6 5.6 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
5.1 10.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
5.1 50.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
4.9 19.7 GO:0051311 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
4.9 19.4 GO:0070829 heterochromatin maintenance(GO:0070829)
4.8 72.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
4.7 14.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
4.7 14.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
4.3 17.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
4.2 21.2 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
4.1 37.2 GO:0033504 floor plate development(GO:0033504)
4.1 61.0 GO:0043249 erythrocyte maturation(GO:0043249)
3.8 56.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
3.7 40.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
3.5 3.5 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
3.4 10.2 GO:0003360 brainstem development(GO:0003360)
3.3 10.0 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
3.2 16.0 GO:0035262 gonad morphogenesis(GO:0035262)
3.2 12.8 GO:0061113 pancreas morphogenesis(GO:0061113)
3.1 9.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.0 15.0 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
3.0 12.0 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
3.0 14.9 GO:0042938 dipeptide transport(GO:0042938)
2.9 2.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.9 52.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
2.9 11.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
2.8 8.4 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
2.7 19.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
2.6 10.6 GO:0070269 pyroptosis(GO:0070269)
2.6 13.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.5 22.9 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
2.5 7.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
2.5 32.0 GO:2000381 negative regulation of mesoderm development(GO:2000381)
2.4 38.8 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
2.3 6.9 GO:0006273 lagging strand elongation(GO:0006273)
2.3 11.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
2.2 44.8 GO:0030903 notochord development(GO:0030903)
2.2 6.7 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
2.2 6.7 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
2.2 10.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.2 6.5 GO:0006545 glycine biosynthetic process(GO:0006545)
2.1 38.1 GO:0007530 sex determination(GO:0007530)
2.1 12.6 GO:0002326 B cell lineage commitment(GO:0002326)
2.1 8.4 GO:0010288 response to lead ion(GO:0010288)
2.1 10.3 GO:0051026 chiasma assembly(GO:0051026)
2.0 44.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
2.0 8.1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
2.0 11.8 GO:0016584 nucleosome positioning(GO:0016584)
2.0 5.9 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
2.0 13.7 GO:0072697 protein localization to cell cortex(GO:0072697)
1.9 13.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
1.9 11.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
1.9 11.1 GO:0036089 cleavage furrow formation(GO:0036089)
1.8 7.4 GO:0072757 cellular response to camptothecin(GO:0072757)
1.8 3.7 GO:0070671 response to interleukin-12(GO:0070671)
1.8 1.8 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
1.8 5.4 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
1.8 21.4 GO:0034501 protein localization to kinetochore(GO:0034501)
1.8 10.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.7 3.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
1.7 31.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
1.6 29.6 GO:0030261 chromosome condensation(GO:0030261)
1.6 4.9 GO:0061144 alveolar secondary septum development(GO:0061144)
1.6 3.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.6 43.4 GO:0006270 DNA replication initiation(GO:0006270)
1.6 7.8 GO:0034421 post-translational protein acetylation(GO:0034421)
1.5 7.7 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.5 17.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.5 30.9 GO:0031297 replication fork processing(GO:0031297)
1.5 3.0 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
1.4 2.8 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.4 5.5 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
1.4 9.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
1.4 36.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.3 9.4 GO:0046060 dATP metabolic process(GO:0046060)
1.3 2.7 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
1.3 5.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
1.3 4.0 GO:0061743 motor learning(GO:0061743)
1.3 2.6 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
1.3 12.9 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
1.3 3.8 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
1.2 5.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
1.2 3.7 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
1.2 4.9 GO:0030091 protein repair(GO:0030091)
1.2 6.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
1.2 12.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.2 25.7 GO:0034508 centromere complex assembly(GO:0034508)
1.2 3.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.2 3.5 GO:0030043 actin filament fragmentation(GO:0030043)
1.1 3.4 GO:0097402 neuroblast migration(GO:0097402)
1.1 5.7 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
1.1 6.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.1 5.7 GO:0042117 monocyte activation(GO:0042117)
1.1 3.4 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
1.1 11.3 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
1.1 12.4 GO:0001675 acrosome assembly(GO:0001675)
1.1 4.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.1 4.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.1 7.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.1 3.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.1 4.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
1.1 7.7 GO:0001842 neural fold formation(GO:0001842)
1.1 2.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.1 3.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.1 3.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
1.0 4.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.0 1.0 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
1.0 3.1 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
1.0 9.2 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
1.0 5.0 GO:1901525 negative regulation of macromitophagy(GO:1901525)
1.0 8.9 GO:0046599 regulation of centriole replication(GO:0046599)
1.0 3.0 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
1.0 9.8 GO:0032682 negative regulation of chemokine production(GO:0032682)
1.0 2.9 GO:0070634 transepithelial ammonium transport(GO:0070634)
1.0 3.8 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.9 6.6 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.9 3.7 GO:0051660 establishment of centrosome localization(GO:0051660)
0.9 17.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.9 5.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.9 8.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.9 9.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.9 2.7 GO:0045004 DNA replication proofreading(GO:0045004)
0.9 4.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.9 7.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.8 8.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.8 5.8 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.8 3.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.8 3.3 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.8 2.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.8 6.5 GO:0006004 fucose metabolic process(GO:0006004)
0.8 2.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.8 3.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.8 7.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.8 0.8 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.8 3.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.8 8.4 GO:0019985 translesion synthesis(GO:0019985)
0.8 1.5 GO:0030539 male genitalia development(GO:0030539)
0.7 6.7 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.7 2.2 GO:0006116 NADH oxidation(GO:0006116)
0.7 5.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.7 12.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.7 14.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.7 18.1 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.7 2.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223) cerebellum vasculature development(GO:0061300)
0.7 5.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.7 12.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.7 6.4 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.7 8.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.7 2.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.7 24.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.7 2.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.7 2.0 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.7 8.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.7 9.8 GO:0097237 cellular response to toxic substance(GO:0097237)
0.7 1.3 GO:0051462 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) positive regulation of cortisol secretion(GO:0051464)
0.7 7.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.7 2.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.6 4.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.6 2.6 GO:0051562 cellular triglyceride homeostasis(GO:0035356) negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.6 5.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.6 1.8 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.6 1.8 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.6 2.4 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.6 2.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.6 5.8 GO:0000729 DNA double-strand break processing(GO:0000729)
0.6 8.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.6 2.9 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.6 2.3 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.6 21.1 GO:0090307 mitotic spindle assembly(GO:0090307)
0.5 20.7 GO:0051310 metaphase plate congression(GO:0051310)
0.5 1.6 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.5 4.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.5 2.7 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.5 2.1 GO:0009414 response to water deprivation(GO:0009414)
0.5 6.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.5 2.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.5 4.7 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.5 1.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 5.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.5 3.6 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.5 1.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 5.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.5 3.6 GO:0048102 autophagic cell death(GO:0048102)
0.5 9.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.5 1.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.5 4.5 GO:0090527 actin filament reorganization(GO:0090527)
0.5 3.0 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.5 2.5 GO:0035878 nail development(GO:0035878)
0.5 3.0 GO:0036337 Fas signaling pathway(GO:0036337)
0.5 2.5 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.5 7.7 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.5 6.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.5 3.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.5 5.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.5 0.9 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.5 9.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 2.7 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.4 1.8 GO:0033260 nuclear DNA replication(GO:0033260)
0.4 1.3 GO:0042732 D-xylose metabolic process(GO:0042732)
0.4 7.5 GO:0060746 parental behavior(GO:0060746)
0.4 6.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.4 2.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.4 0.9 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.4 2.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.4 1.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.4 6.5 GO:0002076 osteoblast development(GO:0002076)
0.4 17.6 GO:0006378 mRNA polyadenylation(GO:0006378)
0.4 10.9 GO:0003416 endochondral bone growth(GO:0003416)
0.4 2.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.4 2.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.4 1.2 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.4 9.5 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.4 1.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4 2.4 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.4 3.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.4 3.6 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.4 1.2 GO:0021764 amygdala development(GO:0021764)
0.4 3.6 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) small RNA loading onto RISC(GO:0070922)
0.4 1.1 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.4 1.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.4 8.6 GO:0022038 corpus callosum development(GO:0022038)
0.4 1.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.4 6.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.1 GO:1903416 response to glycoside(GO:1903416)
0.4 4.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.4 1.8 GO:0016266 O-glycan processing(GO:0016266)
0.4 11.1 GO:0006284 base-excision repair(GO:0006284)
0.4 2.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.3 0.7 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.3 1.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 12.6 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.3 3.3 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.3 2.0 GO:0090383 phagosome acidification(GO:0090383)
0.3 1.3 GO:0070166 enamel mineralization(GO:0070166)
0.3 1.3 GO:0043987 histone-serine phosphorylation(GO:0035404) histone H3-S10 phosphorylation(GO:0043987)
0.3 1.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 1.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.3 3.9 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.3 0.6 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
0.3 1.2 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.3 0.6 GO:0072719 cellular response to cisplatin(GO:0072719)
0.3 4.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.3 0.8 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.3 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 1.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.3 1.4 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.3 12.2 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.3 0.8 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.3 0.8 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.3 9.0 GO:0030517 negative regulation of axon extension(GO:0030517)
0.3 2.2 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.3 4.0 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.3 2.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 1.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 2.6 GO:0016926 protein desumoylation(GO:0016926)
0.3 0.8 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3 2.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 1.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 6.3 GO:0000303 response to superoxide(GO:0000303)
0.2 11.2 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.2 3.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 0.5 GO:0032776 DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.2 2.0 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.2 1.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.2 0.7 GO:0060430 lung saccule development(GO:0060430)
0.2 0.5 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.2 8.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.2 2.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 2.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2 0.9 GO:0035989 tendon development(GO:0035989)
0.2 3.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 3.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 3.4 GO:0032465 regulation of cytokinesis(GO:0032465)
0.2 1.8 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.2 1.6 GO:0014029 neural crest formation(GO:0014029)
0.2 5.1 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.2 1.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 6.6 GO:0007520 myoblast fusion(GO:0007520)
0.2 3.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 0.9 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 6.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 4.2 GO:0001709 cell fate determination(GO:0001709)
0.2 1.0 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.2 0.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 1.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 0.6 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 1.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.2 0.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 1.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 5.3 GO:0018345 protein palmitoylation(GO:0018345)
0.2 1.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.9 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 0.5 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.2 0.5 GO:0070365 hepatocyte differentiation(GO:0070365)
0.2 0.8 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 0.8 GO:1990839 response to endothelin(GO:1990839)
0.2 2.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 2.0 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 1.4 GO:0006817 phosphate ion transport(GO:0006817)
0.2 0.8 GO:0046208 spermine catabolic process(GO:0046208)
0.2 0.9 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.2 0.3 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.2 1.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 1.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 2.3 GO:0035050 embryonic heart tube development(GO:0035050)
0.1 1.0 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.9 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086)
0.1 8.3 GO:0006342 chromatin silencing(GO:0006342)
0.1 3.7 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.8 GO:0051775 response to redox state(GO:0051775)
0.1 2.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.7 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 1.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 9.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.8 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.7 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 1.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 3.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 2.0 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 0.8 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.3 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 1.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 2.4 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.1 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.6 GO:1990776 angiotensin-activated signaling pathway(GO:0038166) cellular response to angiotensin(GO:1904385) response to angiotensin(GO:1990776)
0.1 1.4 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 3.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 11.0 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.1 2.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.2 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.1 0.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 1.8 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 3.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 1.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.7 GO:0021554 optic nerve development(GO:0021554)
0.1 2.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.3 GO:0000389 generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.1 1.3 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 0.3 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1 0.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 1.0 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 4.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 5.1 GO:0000910 cytokinesis(GO:0000910)
0.1 0.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 2.9 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 2.9 GO:0006302 double-strand break repair(GO:0006302)
0.1 2.1 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 0.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.4 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 1.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.8 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 1.1 GO:0050684 regulation of mRNA processing(GO:0050684)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.9 GO:0045087 innate immune response(GO:0045087)
0.1 0.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.2 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1 0.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 5.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 1.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.6 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0097503 sialylation(GO:0097503)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 4.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 1.4 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 3.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 1.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.4 GO:0019098 reproductive behavior(GO:0019098)
0.0 1.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.7 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683)
0.0 0.3 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
10.1 30.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
9.4 46.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
8.0 24.1 GO:1990423 RZZ complex(GO:1990423)
6.1 24.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
6.1 61.3 GO:0000796 condensin complex(GO:0000796)
6.1 36.7 GO:0098536 deuterosome(GO:0098536)
4.8 14.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
4.4 13.1 GO:0035101 FACT complex(GO:0035101)
4.4 21.8 GO:0031523 Myb complex(GO:0031523)
4.3 12.9 GO:0071914 prominosome(GO:0071914)
4.2 21.0 GO:0097149 centralspindlin complex(GO:0097149)
3.6 10.9 GO:0000801 central element(GO:0000801)
3.4 10.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
3.4 13.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
3.3 19.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
3.1 9.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.6 10.6 GO:0061702 inflammasome complex(GO:0061702)
2.4 9.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
2.4 14.2 GO:0070531 BRCA1-A complex(GO:0070531)
2.2 8.9 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
2.2 4.5 GO:0070939 Dsl1p complex(GO:0070939)
2.2 19.7 GO:0072687 meiotic spindle(GO:0072687)
2.2 6.5 GO:0033186 CAF-1 complex(GO:0033186)
2.2 25.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.1 21.1 GO:0001739 sex chromatin(GO:0001739)
2.0 10.2 GO:0035189 Rb-E2F complex(GO:0035189)
1.8 7.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.8 12.7 GO:0001940 male pronucleus(GO:0001940)
1.8 5.4 GO:0071920 cleavage body(GO:0071920)
1.7 6.9 GO:0008623 CHRAC(GO:0008623)
1.7 8.4 GO:0005828 kinetochore microtubule(GO:0005828)
1.6 122.7 GO:0005657 replication fork(GO:0005657)
1.5 7.7 GO:0033010 paranodal junction(GO:0033010)
1.5 4.5 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.4 6.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.4 8.1 GO:0000938 GARP complex(GO:0000938)
1.3 4.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.3 22.2 GO:0044453 nuclear membrane part(GO:0044453)
1.3 42.1 GO:0000788 nuclear nucleosome(GO:0000788)
1.3 6.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.2 7.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.2 20.2 GO:0032593 insulin-responsive compartment(GO:0032593)
1.2 4.8 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.2 3.5 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.1 5.7 GO:0001740 Barr body(GO:0001740)
1.1 10.8 GO:0035102 PRC1 complex(GO:0035102)
1.1 5.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.1 5.4 GO:0097226 sperm mitochondrial sheath(GO:0097226)
1.0 6.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
1.0 8.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.9 2.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.9 3.8 GO:0031084 BLOC-2 complex(GO:0031084)
0.9 6.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.9 16.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.9 12.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.9 6.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.9 7.1 GO:0042382 paraspeckles(GO:0042382)
0.9 8.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.9 5.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.8 7.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.8 2.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.8 8.1 GO:0000974 Prp19 complex(GO:0000974)
0.8 11.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.8 4.0 GO:0044301 climbing fiber(GO:0044301)
0.8 16.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.8 2.3 GO:0031417 NatC complex(GO:0031417)
0.7 4.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.7 4.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.7 8.4 GO:0030057 desmosome(GO:0030057)
0.7 4.9 GO:0070695 FHF complex(GO:0070695)
0.7 8.2 GO:0042555 MCM complex(GO:0042555)
0.7 8.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.6 10.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.6 5.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.6 2.5 GO:0043293 apoptosome(GO:0043293)
0.6 5.0 GO:0002177 manchette(GO:0002177)
0.6 5.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.6 14.7 GO:0051233 spindle midzone(GO:0051233)
0.6 7.2 GO:0044294 dendritic growth cone(GO:0044294)
0.6 3.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.6 57.9 GO:0005814 centriole(GO:0005814)
0.6 90.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.6 1.7 GO:0030905 retromer, tubulation complex(GO:0030905)
0.5 3.7 GO:0097422 tubular endosome(GO:0097422)
0.5 5.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 1.5 GO:0018444 translation release factor complex(GO:0018444)
0.5 4.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.5 2.9 GO:0070847 core mediator complex(GO:0070847)
0.5 6.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 4.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5 8.4 GO:0097470 ribbon synapse(GO:0097470)
0.5 4.6 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.5 3.6 GO:0070652 HAUS complex(GO:0070652)
0.4 1.3 GO:0005927 muscle tendon junction(GO:0005927)
0.4 2.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.4 4.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 1.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 4.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.4 1.9 GO:0032797 SMN complex(GO:0032797)
0.4 3.0 GO:0031415 NatA complex(GO:0031415)
0.4 16.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 15.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 11.9 GO:0005876 spindle microtubule(GO:0005876)
0.4 4.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 2.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.4 3.6 GO:1904115 axon cytoplasm(GO:1904115)
0.4 6.0 GO:0000795 synaptonemal complex(GO:0000795)
0.3 1.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 6.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.3 2.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 1.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.3 1.2 GO:0072487 MSL complex(GO:0072487)
0.3 3.6 GO:0005614 interstitial matrix(GO:0005614)
0.3 3.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.3 5.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 1.9 GO:0042825 TAP complex(GO:0042825)
0.3 1.9 GO:0071203 WASH complex(GO:0071203)
0.2 2.5 GO:0030056 hemidesmosome(GO:0030056)
0.2 11.6 GO:0043034 costamere(GO:0043034)
0.2 5.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 82.9 GO:0000228 nuclear chromosome(GO:0000228)
0.2 8.0 GO:0060077 inhibitory synapse(GO:0060077)
0.2 9.8 GO:0000793 condensed chromosome(GO:0000793)
0.2 0.7 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 1.3 GO:0030914 STAGA complex(GO:0030914)
0.2 13.6 GO:0005902 microvillus(GO:0005902)
0.2 45.6 GO:0005694 chromosome(GO:0005694)
0.2 1.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 0.6 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.2 3.8 GO:0044447 axoneme part(GO:0044447)
0.2 12.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 2.7 GO:0030008 TRAPP complex(GO:0030008)
0.2 4.2 GO:0016459 myosin complex(GO:0016459)
0.2 2.3 GO:0014704 intercalated disc(GO:0014704)
0.2 5.1 GO:0031519 PcG protein complex(GO:0031519)
0.2 5.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 5.4 GO:0016592 mediator complex(GO:0016592)
0.2 46.2 GO:0005667 transcription factor complex(GO:0005667)
0.2 0.9 GO:1990246 uniplex complex(GO:1990246)
0.2 2.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 3.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 1.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.9 GO:0016600 flotillin complex(GO:0016600)
0.2 4.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 7.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 2.0 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 2.2 GO:0042588 zymogen granule(GO:0042588)
0.1 0.4 GO:0042827 platelet dense granule(GO:0042827)
0.1 0.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.3 GO:0090544 BAF-type complex(GO:0090544)
0.1 3.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.9 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 1.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 2.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 6.0 GO:0016605 PML body(GO:0016605)
0.1 3.6 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 2.6 GO:0000922 spindle pole(GO:0000922)
0.1 0.3 GO:0032021 NELF complex(GO:0032021)
0.1 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 13.0 GO:0043292 contractile fiber(GO:0043292)
0.1 1.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 10.5 GO:0001726 ruffle(GO:0001726)
0.1 1.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.6 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.3 GO:0031143 pseudopodium(GO:0031143)
0.1 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.4 GO:0016235 aggresome(GO:0016235)
0.1 0.3 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 5.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 82.9 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 2.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)
0.0 3.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 55.3 GO:0005634 nucleus(GO:0005634)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 57.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
9.4 46.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
8.2 49.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
7.8 23.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
6.0 6.0 GO:0030983 mismatched DNA binding(GO:0030983)
4.7 14.1 GO:0042936 dipeptide transporter activity(GO:0042936)
4.6 23.0 GO:0043515 kinetochore binding(GO:0043515)
4.6 22.9 GO:0042289 MHC class II protein binding(GO:0042289)
4.0 19.8 GO:0000405 bubble DNA binding(GO:0000405)
3.7 26.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
3.4 17.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
3.3 3.3 GO:0042296 ISG15 transferase activity(GO:0042296)
3.3 9.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.9 14.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
2.8 11.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
2.7 16.4 GO:0001069 regulatory region RNA binding(GO:0001069)
2.6 15.9 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
2.4 7.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
2.4 19.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.3 9.1 GO:0070087 chromo shadow domain binding(GO:0070087)
2.3 27.1 GO:0035173 histone kinase activity(GO:0035173)
2.2 6.5 GO:0051870 methotrexate binding(GO:0051870)
1.9 15.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
1.8 11.0 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.8 5.4 GO:0097108 hedgehog family protein binding(GO:0097108)
1.7 10.5 GO:0070644 vitamin D response element binding(GO:0070644)
1.7 12.2 GO:0015616 DNA translocase activity(GO:0015616)
1.7 10.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
1.6 14.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.6 6.5 GO:0042806 fucose binding(GO:0042806)
1.6 25.5 GO:0003680 AT DNA binding(GO:0003680)
1.5 9.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.5 10.6 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
1.5 12.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.4 15.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.4 8.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.4 1.4 GO:0043398 HLH domain binding(GO:0043398)
1.4 9.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.4 5.5 GO:0005113 patched binding(GO:0005113)
1.4 15.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
1.3 12.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
1.3 3.9 GO:0048019 receptor antagonist activity(GO:0048019)
1.2 6.0 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
1.1 7.7 GO:0032794 GTPase activating protein binding(GO:0032794)
1.1 3.2 GO:0070052 collagen V binding(GO:0070052)
1.1 13.9 GO:0038191 neuropilin binding(GO:0038191)
1.1 5.3 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.1 28.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
1.0 7.3 GO:0050693 LBD domain binding(GO:0050693)
1.0 37.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.0 9.2 GO:0034711 inhibin binding(GO:0034711)
1.0 3.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.0 8.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.0 3.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.0 5.0 GO:0050700 CARD domain binding(GO:0050700)
1.0 2.9 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
1.0 3.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
1.0 41.0 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.9 42.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.9 10.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.8 4.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.8 23.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.8 3.3 GO:0070279 vitamin B6 binding(GO:0070279)
0.8 8.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.8 6.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.8 12.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 4.6 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.8 6.0 GO:0036310 annealing helicase activity(GO:0036310)
0.7 3.0 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.7 2.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.7 2.2 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.7 2.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.7 2.1 GO:0019002 GMP binding(GO:0019002)
0.7 5.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.7 2.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.7 4.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.7 2.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.7 3.4 GO:0032027 myosin light chain binding(GO:0032027)
0.7 16.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.6 2.5 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.6 1.9 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.6 5.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 1.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.6 23.3 GO:0001671 ATPase activator activity(GO:0001671)
0.6 3.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6 10.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 5.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.6 1.1 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.6 3.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.6 3.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.6 2.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 3.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.5 13.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 7.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.5 3.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.5 5.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.5 106.2 GO:0042393 histone binding(GO:0042393)
0.5 3.5 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.5 4.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.5 2.5 GO:0038132 neuregulin binding(GO:0038132)
0.5 6.0 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.5 6.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.5 2.5 GO:0034452 dynactin binding(GO:0034452)
0.5 59.6 GO:0004386 helicase activity(GO:0004386)
0.5 1.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.5 16.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.5 4.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.5 5.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.5 1.8 GO:0035877 death effector domain binding(GO:0035877)
0.4 2.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.4 1.8 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.4 20.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.4 20.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 9.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.4 3.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.4 0.8 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.4 1.7 GO:1990460 leptin receptor binding(GO:1990460)
0.4 10.6 GO:0070840 dynein complex binding(GO:0070840)
0.4 2.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.4 1.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 5.0 GO:0050897 cobalt ion binding(GO:0050897)
0.4 6.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.4 2.9 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.4 1.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.4 56.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.4 2.4 GO:0097016 L27 domain binding(GO:0097016)
0.4 0.8 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.4 1.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.4 4.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 1.9 GO:0098634 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-matrix adhesion(GO:0098634)
0.4 2.6 GO:0031419 cobalamin binding(GO:0031419)
0.4 1.9 GO:0004359 glutaminase activity(GO:0004359)
0.4 1.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 1.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 1.8 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.4 4.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 6.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 10.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 1.4 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.3 9.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 2.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 1.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 1.3 GO:0004966 galanin receptor activity(GO:0004966)
0.3 2.0 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.3 6.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 3.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.3 3.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 18.5 GO:0002039 p53 binding(GO:0002039)
0.3 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.3 1.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 1.2 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.3 1.4 GO:0008494 translation activator activity(GO:0008494)
0.3 0.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.3 7.2 GO:0042805 actinin binding(GO:0042805)
0.3 60.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3 0.8 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.3 3.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 1.3 GO:1990188 euchromatin binding(GO:1990188)
0.3 3.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.3 0.8 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 1.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 1.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 0.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 1.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 2.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 14.8 GO:0003777 microtubule motor activity(GO:0003777)
0.2 5.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 3.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 25.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 1.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 4.6 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.2 18.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 0.8 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.2 2.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 0.7 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.2 2.4 GO:0048156 tau protein binding(GO:0048156)
0.2 5.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 1.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 2.4 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.2 2.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 0.7 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.2 0.8 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 9.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 4.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 5.4 GO:0030332 cyclin binding(GO:0030332)
0.1 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.6 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 2.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 12.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.7 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 1.4 GO:0043495 protein anchor(GO:0043495)
0.1 1.2 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.1 GO:1990239 steroid hormone binding(GO:1990239)
0.1 2.1 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.2 GO:0019210 kinase inhibitor activity(GO:0019210)
0.1 5.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 2.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 11.5 GO:0051015 actin filament binding(GO:0051015)
0.1 1.9 GO:0004707 MAP kinase activity(GO:0004707)
0.1 2.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 1.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 3.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.6 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 5.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.2 GO:0043022 ribosome binding(GO:0043022)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.6 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 2.0 GO:0005112 Notch binding(GO:0005112)
0.1 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.2 GO:0044020 snoRNP binding(GO:0030519) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.8 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 11.7 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 1.6 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.8 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 0.9 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 74.8 GO:0003677 DNA binding(GO:0003677)
0.1 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 9.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 2.4 GO:0017022 myosin binding(GO:0017022)
0.1 7.6 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 3.3 GO:0003682 chromatin binding(GO:0003682)
0.0 1.0 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 12.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 4.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 6.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 1.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 4.5 GO:0005525 GTP binding(GO:0005525)
0.0 1.0 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 42.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
2.5 22.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.3 112.6 PID_AURORA_B_PATHWAY Aurora B signaling
2.1 167.5 PID_E2F_PATHWAY E2F transcription factor network
1.6 69.0 PID_ATR_PATHWAY ATR signaling pathway
1.2 37.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.8 2.4 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.7 19.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.6 7.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.6 2.9 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6 20.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.6 8.4 PID_BARD1_PATHWAY BARD1 signaling events
0.5 9.0 PID_MYC_PATHWAY C-MYC pathway
0.5 5.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.5 12.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.5 14.0 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.5 8.6 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 7.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.5 15.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.5 23.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.5 4.5 PID_IL5_PATHWAY IL5-mediated signaling events
0.4 9.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.4 2.4 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 17.8 NABA_COLLAGENS Genes encoding collagen proteins
0.4 28.6 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 1.0 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.3 12.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.3 2.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.3 13.1 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.3 10.7 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.2 6.0 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 2.9 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.2 3.4 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.2 8.0 PID_PLK1_PATHWAY PLK1 signaling events
0.2 6.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 2.6 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.2 5.1 PID_ALK1_PATHWAY ALK1 signaling events
0.2 1.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 2.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 17.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 5.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 4.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 4.6 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 3.1 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.9 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.1 1.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.6 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.0 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.3 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.8 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.5 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 1.0 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 67.5 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
3.7 73.4 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
2.9 20.0 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
2.2 24.6 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
2.1 19.2 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.1 33.9 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.7 12.1 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
1.5 30.1 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.4 14.3 REACTOME_LAGGING_STRAND_SYNTHESIS Genes involved in Lagging Strand Synthesis
1.4 11.2 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.3 69.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.3 10.2 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
1.2 20.7 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
1.2 9.4 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
1.1 30.2 REACTOME_KINESINS Genes involved in Kinesins
1.1 15.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.0 11.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.0 22.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.9 9.8 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.8 30.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.8 22.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.7 5.7 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.7 7.0 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.7 11.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.7 17.8 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.7 57.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.6 8.9 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.6 9.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.6 37.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.6 27.6 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.5 3.7 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.5 3.7 REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER Genes involved in Transcription-coupled NER (TC-NER)
0.5 15.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4 2.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.4 3.6 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.4 5.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 6.2 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.4 4.5 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.4 18.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.4 5.7 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3 3.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.3 1.0 REACTOME_MITOTIC_G2_G2_M_PHASES Genes involved in Mitotic G2-G2/M phases
0.3 4.3 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.3 8.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 2.5 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.3 3.0 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3 4.0 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 6.6 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3 4.6 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.3 10.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.2 8.3 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.2 3.2 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 4.1 REACTOME_RNA_POL_I_TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.2 2.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.0 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.2 4.3 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.2 2.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.2 3.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 0.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.2 7.1 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.2 0.8 REACTOME_SIGNALLING_TO_RAS Genes involved in Signalling to RAS
0.2 2.2 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.2 1.0 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.2 5.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 2.1 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.2 4.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.2 4.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 2.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 4.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 4.1 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.2 3.9 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 4.5 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 2.6 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.2 4.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 2.5 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 0.6 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ Genes involved in Formation of RNA Pol II elongation complex
0.2 3.2 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 10.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 4.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.8 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 1.5 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.1 3.8 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 7.4 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 29.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 0.3 REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1 1.7 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.9 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.8 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 1.2 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.1 2.2 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.7 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.6 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 4.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.5 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.6 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 2.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.4 REACTOME_APOPTOTIC_EXECUTION_PHASE Genes involved in Apoptotic execution phase
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly