Motif ID: Ehf

Z-value: 0.267


Transcription factors associated with Ehf:

Gene SymbolEntrez IDGene Name
Ehf ENSMUSG00000012350.9 Ehf



Activity profile for motif Ehf.

activity profile for motif Ehf


Sorted Z-values histogram for motif Ehf

Sorted Z-values for motif Ehf



Network of associatons between targets according to the STRING database.



First level regulatory network of Ehf

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_37477768 1.434 ENSMUST00000051442.5
 Pcdhb16
protocadherin beta 16
chr9_-_106447584 1.231 ENSMUST00000171678.1
ENSMUST00000048685.6
ENSMUST00000171925.1
 Abhd14a


abhydrolase domain containing 14A


chr11_-_54860564 1.230 ENSMUST00000144164.1
 Lyrm7
LYR motif containing 7
chr9_+_32116040 1.124 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr4_+_48049080 1.098 ENSMUST00000153369.1
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr6_+_142413833 1.037 ENSMUST00000126521.2
 B230216G23Rik
RIKEN cDNA B230216G23 gene
chr13_+_109260481 1.007 ENSMUST00000153234.1
 Pde4d
phosphodiesterase 4D, cAMP specific
chr6_+_142413441 0.964 ENSMUST00000088263.4
 B230216G23Rik
RIKEN cDNA B230216G23 gene
chr6_+_142414012 0.902 ENSMUST00000141548.1
 B230216G23Rik
RIKEN cDNA B230216G23 gene
chr9_-_107541816 0.842 ENSMUST00000041459.3
 Cyb561d2
cytochrome b-561 domain containing 2
chr15_+_4375462 0.688 ENSMUST00000061925.4
 Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr3_+_28781305 0.657 ENSMUST00000060500.7
 Eif5a2
eukaryotic translation initiation factor 5A2
chr1_-_153549697 0.653 ENSMUST00000041874.7
 Npl
N-acetylneuraminate pyruvate lyase
chr11_+_70764209 0.570 ENSMUST00000060444.5
 Zfp3
zinc finger protein 3
chr11_-_96075655 0.492 ENSMUST00000090541.5
 Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr18_-_24603791 0.444 ENSMUST00000070726.3
 Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr3_-_95855860 0.417 ENSMUST00000015892.7
 Prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr4_-_64276595 0.399 ENSMUST00000141162.1
 Gm11217
predicted gene 11217
chr18_-_24603464 0.394 ENSMUST00000154205.1
 Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr11_-_96075581 0.388 ENSMUST00000107686.1
ENSMUST00000107684.1
 Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr3_+_116594959 0.362 ENSMUST00000029571.8
 Sass6
spindle assembly 6 homolog (C. elegans)
chr3_-_95855753 0.337 ENSMUST00000161476.1
 Prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr9_+_107542209 0.318 ENSMUST00000010201.3
 Nprl2
nitrogen permease regulator-like 2
chr2_+_129100995 0.280 ENSMUST00000103205.4
ENSMUST00000028874.7
 Polr1b

polymerase (RNA) I polypeptide B

chr11_+_72689997 0.249 ENSMUST00000155998.1
 Ankfy1
ankyrin repeat and FYVE domain containing 1
chr16_+_16302955 0.238 ENSMUST00000159962.1
ENSMUST00000059955.8
 Yars2

tyrosyl-tRNA synthetase 2 (mitochondrial)

chr5_+_121749196 0.221 ENSMUST00000161064.1
 Atxn2
ataxin 2
chr6_-_30915552 0.212 ENSMUST00000048580.1
 Tsga13
testis specific gene A13
chr5_+_90794530 0.166 ENSMUST00000031322.6
 Cxcl15
chemokine (C-X-C motif) ligand 15
chr2_+_164805082 0.066 ENSMUST00000052107.4
 Zswim3
zinc finger SWIM-type containing 3
chr1_+_146495621 0.063 ENSMUST00000074622.4
 Brinp3
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr15_-_73184840 0.058 ENSMUST00000044113.10
 Ago2
argonaute RISC catalytic subunit 2
chr13_-_8870999 0.053 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
 Wdr37


WD repeat domain 37


chr4_-_120815703 0.051 ENSMUST00000120779.1
 Nfyc
nuclear transcription factor-Y gamma

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 1.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 1.0 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.4 GO:0007099 centriole replication(GO:0007099)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.1 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination