Motif ID: Emx1_Emx2

Z-value: 0.557

Transcription factors associated with Emx1_Emx2:

Gene SymbolEntrez IDGene Name
Emx1 ENSMUSG00000033726.8 Emx1
Emx2 ENSMUSG00000043969.4 Emx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Emx1mm10_v2_chr6_+_85187438_851875100.271.6e-02Click!
Emx2mm10_v2_chr19_+_59458372_594584500.075.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Emx1_Emx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_118961578 5.564 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr3_+_127633134 5.027 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr7_-_103827922 4.890 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr4_-_82505274 4.324 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr4_-_82505749 4.156 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr4_-_82505707 3.551 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr17_-_36032682 3.229 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr2_-_160619971 2.945 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chrX_+_106920618 2.238 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr8_-_21906412 2.055 ENSMUST00000051965.4
Defb11
defensin beta 11
chr13_-_97747373 2.026 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr17_-_48432723 2.023 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr3_-_49757257 1.969 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr18_+_57142782 1.964 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr13_-_97747399 1.960 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr12_-_98577940 1.827 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr14_+_26259109 1.817 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr6_+_42245907 1.792 ENSMUST00000031897.5
Gstk1
glutathione S-transferase kappa 1
chr7_+_126781483 1.766 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr3_+_90541146 1.658 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr5_-_28210022 1.656 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr17_-_31636631 1.470 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr10_+_90071095 1.465 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_+_26119811 1.463 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr1_-_144177259 1.331 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr10_-_42583628 1.283 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr8_-_4779513 1.250 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr3_-_63851251 1.247 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr16_-_63864114 1.222 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr6_-_57535422 1.219 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr9_+_65890237 1.213 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr14_+_46832127 1.191 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr10_+_79996479 1.190 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr11_+_109543694 1.184 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr13_+_23555023 1.181 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr14_+_26119173 1.171 ENSMUST00000174564.1
Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 1.171 ENSMUST00000172517.1
Duxbl3
double homeobox B-like 3
chr14_+_25979401 1.161 ENSMUST00000173580.1
Duxbl1
double homeobox B-like 1
chr6_-_144209558 1.145 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr6_-_144209448 1.144 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr6_-_144209471 1.113 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr12_-_90969768 1.080 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr7_-_115846080 1.073 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr6_-_101377342 1.069 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr17_+_40115358 1.046 ENSMUST00000061746.7
Gm7148
predicted gene 7148
chr14_+_25980039 1.045 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr4_+_110397661 1.017 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr12_-_84617326 1.006 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr2_-_67194695 0.993 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr18_-_15403680 0.987 ENSMUST00000079081.6
Aqp4
aquaporin 4
chr10_-_88605017 0.948 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr8_+_69300776 0.904 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr17_+_45734506 0.864 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr13_+_23763660 0.846 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr4_+_110397764 0.822 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chrX_-_102505359 0.776 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr11_+_97029925 0.775 ENSMUST00000021249.4
Scrn2
secernin 2
chr16_-_44016387 0.765 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr12_-_54999102 0.764 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr14_+_53324632 0.758 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr7_-_5413145 0.730 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr15_-_103366763 0.683 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr14_+_55560010 0.660 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr2_+_110597298 0.656 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr2_+_175469985 0.635 ENSMUST00000109042.3
ENSMUST00000109002.2
ENSMUST00000109043.2
ENSMUST00000143490.1
Gm8923



predicted gene 8923



chr3_+_88716838 0.633 ENSMUST00000029692.8
ENSMUST00000171645.1
Rit1

Ras-like without CAAX 1

chr3_+_88716884 0.620 ENSMUST00000172252.1
Rit1
Ras-like without CAAX 1
chrM_+_11734 0.617 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr2_-_73580288 0.596 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr3_+_32708546 0.592 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr12_-_98259416 0.591 ENSMUST00000021390.7
Galc
galactosylceramidase
chrX_+_106027259 0.590 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr2_-_175703646 0.588 ENSMUST00000109027.2
ENSMUST00000179061.1
ENSMUST00000131041.1
Gm4245


predicted gene 4245


chr2_+_175372436 0.587 ENSMUST00000131676.1
ENSMUST00000109048.2
ENSMUST00000109047.2
Gm4723


predicted gene 4723


chrX_+_106027300 0.585 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr10_-_86011833 0.568 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr7_-_142661858 0.557 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr10_-_25297055 0.555 ENSMUST00000177124.1
Akap7
A kinase (PRKA) anchor protein 7
chr7_+_39588931 0.553 ENSMUST00000178791.1
ENSMUST00000098511.3
Gm2058

predicted gene 2058

chr9_+_78191966 0.548 ENSMUST00000034903.5
Gsta4
glutathione S-transferase, alpha 4
chr2_+_36230426 0.521 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr7_-_84679346 0.498 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr1_-_133610253 0.477 ENSMUST00000166915.1
Snrpe
small nuclear ribonucleoprotein E
chr4_-_155645408 0.460 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr17_-_45599603 0.436 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr10_-_76110956 0.423 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chrX_-_74393003 0.419 ENSMUST00000015427.6
Fam3a
family with sequence similarity 3, member A
chr2_-_28583189 0.406 ENSMUST00000113889.2
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr13_-_4609122 0.396 ENSMUST00000110691.3
ENSMUST00000091848.5
Akr1e1

aldo-keto reductase family 1, member E1

chr3_+_137341103 0.388 ENSMUST00000119475.1
Emcn
endomucin
chr3_-_130730375 0.374 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr16_-_97170707 0.373 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chrX_+_8271133 0.362 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr2_-_28583239 0.361 ENSMUST00000028157.8
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr4_-_86669492 0.359 ENSMUST00000149700.1
Plin2
perilipin 2
chr9_+_72958785 0.348 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr16_-_59553970 0.344 ENSMUST00000139989.1
Crybg3
beta-gamma crystallin domain containing 3
chr2_+_144594054 0.341 ENSMUST00000136628.1
Gm561
predicted gene 561
chr10_+_20347788 0.339 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr14_+_58893465 0.337 ENSMUST00000079960.1
Rpl13-ps3
ribosomal protein L13, pseudogene 3
chr17_-_32822200 0.335 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr3_-_146495115 0.329 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr13_-_106847267 0.325 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr5_-_65428354 0.325 ENSMUST00000131263.1
Ugdh
UDP-glucose dehydrogenase
chr2_+_119047129 0.303 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr7_-_19573343 0.300 ENSMUST00000051364.3
Gemin7
gem (nuclear organelle) associated protein 7
chr16_+_21794320 0.299 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr13_+_94976435 0.285 ENSMUST00000160409.1
ENSMUST00000159647.1
ENSMUST00000167155.1
Wdr41


WD repeat domain 41


chr12_+_80463095 0.272 ENSMUST00000038185.8
Exd2
exonuclease 3'-5' domain containing 2
chr4_-_11254248 0.253 ENSMUST00000044616.3
ENSMUST00000108319.2
ENSMUST00000108318.2
Ints8


integrator complex subunit 8


chr10_+_128322443 0.235 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr10_-_127030789 0.225 ENSMUST00000120547.1
ENSMUST00000152054.1
Tsfm

Ts translation elongation factor, mitochondrial

chrX_-_102157065 0.222 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr17_+_14943184 0.219 ENSMUST00000052691.8
ENSMUST00000164837.2
ENSMUST00000174004.1
1600012H06Rik


RIKEN cDNA 1600012H06 gene


chr3_+_137341067 0.216 ENSMUST00000122064.1
Emcn
endomucin
chr7_-_101845300 0.209 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chr2_+_69789647 0.208 ENSMUST00000112266.1
Phospho2
phosphatase, orphan 2
chr7_-_42706369 0.206 ENSMUST00000180131.1
Gm17067
predicted gene 17067
chr7_-_38019505 0.201 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr9_-_15301555 0.194 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr12_-_12940600 0.190 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr10_-_49783259 0.186 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr17_+_46772635 0.176 ENSMUST00000071430.5
2310039H08Rik
RIKEN cDNA 2310039H08 gene
chr18_-_66002612 0.169 ENSMUST00000120461.1
ENSMUST00000048260.7
Lman1

lectin, mannose-binding, 1

chr9_-_124304718 0.168 ENSMUST00000071300.6
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr17_-_56036546 0.157 ENSMUST00000003268.9
Sh3gl1
SH3-domain GRB2-like 1
chr8_+_34054622 0.156 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr4_-_64276595 0.149 ENSMUST00000141162.1
Gm11217
predicted gene 11217
chr6_-_145047636 0.144 ENSMUST00000149769.1
Bcat1
branched chain aminotransferase 1, cytosolic
chr2_-_119662756 0.143 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chrX_-_160138375 0.137 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr12_+_36314160 0.130 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr15_+_85510812 0.127 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr7_-_125491397 0.123 ENSMUST00000138616.1
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr14_-_18893376 0.121 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chrX_+_159303266 0.116 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr2_-_155930018 0.114 ENSMUST00000152766.1
ENSMUST00000139232.1
ENSMUST00000109632.1
ENSMUST00000006036.6
ENSMUST00000142655.1
ENSMUST00000159238.1
Uqcc1





ubiquinol-cytochrome c reductase complex assembly factor 1





chr14_+_118137101 0.114 ENSMUST00000022728.2
Gpr180
G protein-coupled receptor 180
chr3_-_37125943 0.105 ENSMUST00000029275.5
Il2
interleukin 2
chr13_-_23934156 0.104 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr12_-_56345862 0.099 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr3_+_121531603 0.098 ENSMUST00000180804.1
A530020G20Rik
RIKEN cDNA A530020G20 gene
chr7_+_126976338 0.083 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr8_-_8690493 0.070 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr6_+_66896480 0.070 ENSMUST00000114222.1
Gng12
guanine nucleotide binding protein (G protein), gamma 12
chr2_-_34826071 0.069 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr12_-_87444017 0.061 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr4_-_150914401 0.061 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr6_-_129533267 0.052 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr2_+_30171486 0.049 ENSMUST00000015481.5
Endog
endonuclease G
chr8_+_45507768 0.048 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr17_-_24479034 0.048 ENSMUST00000179163.1
ENSMUST00000070888.6
Mlst8

MTOR associated protein, LST8 homolog (S. cerevisiae)

chr17_-_47043039 0.047 ENSMUST00000075152.5
Gm4945
predicted gene 4945
chr6_-_145047725 0.046 ENSMUST00000123930.1
Bcat1
branched chain aminotransferase 1, cytosolic
chr8_+_72219726 0.040 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr6_-_115037824 0.037 ENSMUST00000174848.1
ENSMUST00000032461.5
Tamm41

TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)

chr14_-_57133585 0.036 ENSMUST00000039380.8
Gjb6
gap junction protein, beta 6
chr11_+_72689997 0.034 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr10_+_52022502 0.025 ENSMUST00000163017.1
ENSMUST00000058347.4
Vgll2

vestigial like 2 homolog (Drosophila)

chr18_-_73754457 0.024 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chrX_+_106187100 0.022 ENSMUST00000081593.6
Pgk1
phosphoglycerate kinase 1
chr3_+_106034661 0.021 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr7_-_143649614 0.020 ENSMUST00000129476.1
ENSMUST00000084396.3
ENSMUST00000075588.6
ENSMUST00000146692.1
Tnfrsf22



tumor necrosis factor receptor superfamily, member 22



chr3_+_32436376 0.017 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr5_+_135009152 0.013 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr9_-_15279860 0.006 ENSMUST00000034411.8
Med17
mediator complex subunit 17
chr17_-_45686899 0.004 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr2_+_129100995 0.003 ENSMUST00000103205.4
ENSMUST00000028874.7
Polr1b

polymerase (RNA) I polypeptide B


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.1 3.2 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.7 2.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 4.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.5 1.5 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.5 1.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 1.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.4 3.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.4 1.2 GO:1904959 elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.3 0.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 1.8 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.2 1.0 GO:0070295 renal water absorption(GO:0070295)
0.2 0.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 1.2 GO:0016584 nucleosome positioning(GO:0016584)
0.2 1.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.4 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.1 0.5 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.4 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 1.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 2.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.6 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 5.8 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.1 0.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.7 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 5.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.3 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) regulation of cellular amino acid biosynthetic process(GO:2000282) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.1 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 2.2 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 2.1 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 1.7 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.7 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.0 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 12.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 3.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.8 GO:0008623 CHRAC(GO:0008623)
0.2 0.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 3.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.2 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.5 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 3.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
1.2 4.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.5 2.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.5 1.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.4 3.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.4 1.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 1.2 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3 12.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 2.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.3 2.0 GO:0001849 complement component C1q binding(GO:0001849)
0.3 0.8 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.2 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 1.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.0 GO:0015288 porin activity(GO:0015288)
0.1 0.3 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.1 5.0 GO:0070888 E-box binding(GO:0070888)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 1.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.2 GO:0051870 methotrexate binding(GO:0051870)
0.1 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.2 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.1 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.6 GO:0016208 AMP binding(GO:0016208)
0.0 2.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.5 GO:0004601 peroxidase activity(GO:0004601)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 2.2 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.7 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 1.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID_MYC_PATHWAY C-MYC pathway
0.0 0.6 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.0 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.3 1.8 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 2.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 1.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.0 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.0 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 0.6 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.3 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane