Motif ID: Esrrb_Esrra

Z-value: 1.322

Transcription factors associated with Esrrb_Esrra:

Gene SymbolEntrez IDGene Name
Esrra ENSMUSG00000024955.7 Esrra
Esrrb ENSMUSG00000021255.11 Esrrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esrrbmm10_v2_chr12_+_86421628_86421662-0.171.3e-01Click!
Esrramm10_v2_chr19_-_6921753_6921803-0.123.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Esrrb_Esrra

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_61523889 24.485 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr11_+_7063423 22.003 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr19_-_57314896 17.518 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr3_-_54915867 14.812 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr2_+_121357714 14.524 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr4_+_13751297 14.508 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_110343009 13.774 ENSMUST00000058016.9
ENSMUST00000112478.3
P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr8_+_124793013 13.641 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr8_+_124793061 13.604 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr15_-_79804717 12.030 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr5_+_63649335 11.894 ENSMUST00000159584.1
3110047P20Rik
RIKEN cDNA 3110047P20 gene
chrX_-_72656135 11.771 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr2_+_121358591 11.770 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr7_-_74554474 11.671 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr19_+_6399857 11.231 ENSMUST00000146601.1
ENSMUST00000150713.1
Rasgrp2

RAS, guanyl releasing protein 2

chr6_+_38663061 11.063 ENSMUST00000114874.3
Clec2l
C-type lectin domain family 2, member L
chr19_+_6400523 10.792 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr11_+_42419729 10.742 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr7_-_141429351 9.982 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
Cend1


cell cycle exit and neuronal differentiation 1


chr8_-_13494479 9.936 ENSMUST00000033828.5
Gas6
growth arrest specific 6
chr19_-_5085483 9.814 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr11_+_98741805 9.535 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr1_-_167393826 9.398 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr1_-_84696182 9.329 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr9_-_106656081 9.309 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr17_-_83631892 9.205 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr15_+_84669565 9.012 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr7_+_46847128 8.883 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr7_-_141429433 8.636 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr3_-_36690118 8.582 ENSMUST00000029271.4
Trpc3
transient receptor potential cation channel, subfamily C, member 3
chr6_-_113501818 8.385 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr15_+_3270767 8.367 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr9_-_70141484 8.300 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr7_-_98162318 8.160 ENSMUST00000107112.1
Capn5
calpain 5
chr7_-_74554726 8.135 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr13_-_51567084 8.088 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr10_+_110920170 7.945 ENSMUST00000020403.5
Csrp2
cysteine and glycine-rich protein 2
chr13_-_102958084 7.935 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr10_+_79716588 7.565 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr2_+_140170641 7.308 ENSMUST00000044825.4
Ndufaf5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr4_+_138250403 7.284 ENSMUST00000105818.1
ENSMUST00000105824.1
ENSMUST00000124239.1
Kif17
Sh2d5

kinesin family member 17
SH2 domain containing 5

chr17_+_28575718 7.280 ENSMUST00000080780.6
Lhfpl5
lipoma HMGIC fusion partner-like 5
chr4_+_99929414 7.275 ENSMUST00000058351.9
Pgm2
phosphoglucomutase 2
chr19_+_6399746 7.120 ENSMUST00000113468.1
Rasgrp2
RAS, guanyl releasing protein 2
chr1_+_75375271 7.096 ENSMUST00000087122.5
Speg
SPEG complex locus
chr12_-_86988676 7.072 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr6_-_148444336 6.963 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chrX_-_141874870 6.919 ENSMUST00000182079.1
Gm15294
predicted gene 15294
chr14_-_70630149 6.843 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr2_+_170731807 6.695 ENSMUST00000029075.4
Dok5
docking protein 5
chr2_-_167188787 6.691 ENSMUST00000059826.8
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
chr6_-_91473361 6.659 ENSMUST00000040835.7
Chchd4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr6_-_59426279 6.579 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr4_+_42917234 6.476 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr6_+_91157373 6.466 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr15_-_79285502 6.440 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr6_+_91156665 6.429 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr5_-_146585239 6.398 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12
chr4_+_42916647 6.384 ENSMUST00000132173.1
ENSMUST00000107975.1
N28178

expressed sequence N28178

chr4_+_138250462 6.360 ENSMUST00000105823.1
Sh2d5
SH2 domain containing 5
chr10_+_128083273 6.154 ENSMUST00000026459.5
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr1_-_134235420 6.101 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr12_+_109545390 6.062 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr4_-_68954351 6.056 ENSMUST00000030036.5
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr19_-_47090610 5.945 ENSMUST00000096014.3
Usmg5
upregulated during skeletal muscle growth 5
chr11_-_4704334 5.921 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr16_-_91931643 5.905 ENSMUST00000023677.3
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr10_-_78464853 5.896 ENSMUST00000105385.1
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr11_-_3504766 5.840 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr15_+_82256023 5.826 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr6_+_91156772 5.801 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chr4_+_123183722 5.582 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr14_-_21848924 5.438 ENSMUST00000124549.1
Comtd1
catechol-O-methyltransferase domain containing 1
chr4_+_99955715 5.327 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr10_-_78464969 5.300 ENSMUST00000041616.8
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr9_+_44043384 5.284 ENSMUST00000114840.1
Thy1
thymus cell antigen 1, theta
chr2_-_73911323 5.255 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr11_+_75193783 5.248 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr2_+_121295437 5.214 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chr19_-_43524462 5.109 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr4_-_139131058 5.041 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr11_+_6415443 5.033 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr11_+_120484613 5.017 ENSMUST00000043627.7
Mrpl12
mitochondrial ribosomal protein L12
chr15_+_23036449 4.978 ENSMUST00000164787.1
Cdh18
cadherin 18
chr12_-_67221221 4.921 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr2_+_178119166 4.910 ENSMUST00000108916.1
Phactr3
phosphatase and actin regulator 3
chr11_+_83409655 4.846 ENSMUST00000175848.1
ENSMUST00000108140.3
Rasl10b

RAS-like, family 10, member B

chr15_+_30172570 4.820 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr5_-_24995748 4.738 ENSMUST00000076306.5
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr4_-_122961173 4.632 ENSMUST00000030408.5
ENSMUST00000127047.1
Mfsd2a

major facilitator superfamily domain containing 2A

chr1_+_131970589 4.594 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr11_-_54860564 4.552 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr19_-_46327121 4.545 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr1_+_34801704 4.545 ENSMUST00000047664.9
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr6_-_113531575 4.455 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr10_-_71344933 4.450 ENSMUST00000045887.8
Cisd1
CDGSH iron sulfur domain 1
chr8_+_36457548 4.341 ENSMUST00000135373.1
ENSMUST00000147525.1
6430573F11Rik

RIKEN cDNA 6430573F11 gene

chr14_+_58072686 4.325 ENSMUST00000022545.7
Fgf9
fibroblast growth factor 9
chr2_+_178118975 4.271 ENSMUST00000108917.1
Phactr3
phosphatase and actin regulator 3
chr7_-_31126945 4.247 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr11_+_83409137 4.223 ENSMUST00000021022.3
Rasl10b
RAS-like, family 10, member B
chr11_-_55033398 4.204 ENSMUST00000108883.3
ENSMUST00000102727.2
Anxa6

annexin A6

chr19_-_7217549 4.171 ENSMUST00000039758.4
Cox8a
cytochrome c oxidase subunit VIIIa
chr18_+_77773956 4.169 ENSMUST00000114748.1
Atp5a1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr1_-_124045247 4.147 ENSMUST00000112603.2
Dpp10
dipeptidylpeptidase 10
chr11_-_20831009 4.088 ENSMUST00000047028.8
Lgalsl
lectin, galactoside binding-like
chr11_+_69088490 4.079 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chrX_-_36991724 4.050 ENSMUST00000152291.1
Sept6
septin 6
chr3_+_68584154 4.039 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr3_-_107517321 4.037 ENSMUST00000166892.1
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr4_-_36136463 3.991 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr17_-_35188427 3.983 ENSMUST00000097336.4
Lst1
leukocyte specific transcript 1
chr9_+_54586450 3.928 ENSMUST00000167866.1
Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr15_+_78430086 3.916 ENSMUST00000162808.1
Kctd17
potassium channel tetramerisation domain containing 17
chr4_-_40279389 3.908 ENSMUST00000108108.2
ENSMUST00000095128.3
Ndufb6

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6

chr5_+_37028329 3.868 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr1_+_36691487 3.858 ENSMUST00000081180.4
Cox5b
cytochrome c oxidase subunit Vb
chr12_+_105032638 3.851 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr6_+_113697050 3.850 ENSMUST00000089018.4
Tatdn2
TatD DNase domain containing 2
chr4_-_45108038 3.829 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr2_-_152951688 3.820 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr1_+_134193432 3.818 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr19_+_6400611 3.806 ENSMUST00000113467.1
Rasgrp2
RAS, guanyl releasing protein 2
chr2_-_84678051 3.783 ENSMUST00000053664.8
ENSMUST00000111664.1
Tmx2

thioredoxin-related transmembrane protein 2

chr11_-_53430779 3.778 ENSMUST00000061326.4
ENSMUST00000109021.3
Uqcrq

ubiquinol-cytochrome c reductase, complex III subunit VII

chr18_-_60624304 3.753 ENSMUST00000097566.3
Synpo
synaptopodin
chr17_+_29360923 3.721 ENSMUST00000024810.6
Fgd2
FYVE, RhoGEF and PH domain containing 2
chr2_+_178141920 3.688 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr1_+_63176818 3.685 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr1_+_82724909 3.648 ENSMUST00000073025.5
ENSMUST00000161648.1
ENSMUST00000160786.1
ENSMUST00000162003.1
Mff



mitochondrial fission factor



chr5_-_9725305 3.640 ENSMUST00000004076.3
Grm3
glutamate receptor, metabotropic 3
chr4_-_116017854 3.614 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr2_-_26021679 3.538 ENSMUST00000036509.7
Ubac1
ubiquitin associated domain containing 1
chrX_+_135993820 3.537 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr4_-_118134869 3.492 ENSMUST00000097912.1
ENSMUST00000030263.2
ENSMUST00000106410.1
St3gal3


ST3 beta-galactoside alpha-2,3-sialyltransferase 3


chr12_-_111672290 3.483 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr17_-_35910032 3.482 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr12_-_111966954 3.422 ENSMUST00000021719.5
2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr19_-_5366626 3.421 ENSMUST00000025762.8
Banf1
barrier to autointegration factor 1
chr13_-_9878998 3.405 ENSMUST00000063093.9
Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr11_-_42000284 3.380 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr2_+_32628390 3.350 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr1_+_75382114 3.339 ENSMUST00000113590.1
ENSMUST00000148515.1
Speg

SPEG complex locus

chr12_-_71136611 3.335 ENSMUST00000021486.8
ENSMUST00000166120.1
Timm9

translocase of inner mitochondrial membrane 9

chr10_+_14523062 3.322 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr1_+_72824482 3.264 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr9_-_107710475 3.264 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_87573825 3.230 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr13_+_119690462 3.227 ENSMUST00000179869.1
Hmgcs1
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr15_+_27025386 3.208 ENSMUST00000169678.2
Gm6576
predicted gene 6576
chr2_+_151542483 3.202 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr5_+_34336289 3.142 ENSMUST00000182709.1
ENSMUST00000030992.6
Rnf4

ring finger protein 4

chr2_-_26021532 3.123 ENSMUST00000136750.1
Ubac1
ubiquitin associated domain containing 1
chr2_-_152951547 3.095 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chrX_-_71492592 3.095 ENSMUST00000080035.4
Cd99l2
CD99 antigen-like 2
chr18_+_37955544 3.087 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr2_-_7395879 3.086 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr17_-_25868727 3.083 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr19_-_37178011 3.059 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr7_-_19715395 3.053 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr11_-_42000532 3.053 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr6_+_96115249 3.048 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr19_-_6980420 3.007 ENSMUST00000070878.8
ENSMUST00000177752.1
Fkbp2

FK506 binding protein 2

chr14_+_32321987 2.996 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr15_-_35938186 2.969 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr7_+_30712209 2.966 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr9_-_114026711 2.957 ENSMUST00000117537.1
ENSMUST00000035090.7
Fbxl2

F-box and leucine-rich repeat protein 2

chr11_-_69560186 2.942 ENSMUST00000004036.5
Efnb3
ephrin B3
chr7_+_28440927 2.934 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr18_+_37955685 2.896 ENSMUST00000169498.2
Rell2
RELT-like 2
chr10_+_94198955 2.881 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr4_+_137681663 2.873 ENSMUST00000047243.5
Rap1gap
Rap1 GTPase-activating protein
chr9_+_109931774 2.853 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr19_-_3912711 2.847 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr5_-_143909782 2.841 ENSMUST00000031613.4
ENSMUST00000100483.2
Aimp2

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

chr15_-_64382908 2.833 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
Asap1



ArfGAP with SH3 domain, ankyrin repeat and PH domain1



chr8_+_71464910 2.833 ENSMUST00000048914.6
Mrpl34
mitochondrial ribosomal protein L34
chr15_-_35938009 2.819 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr13_+_97071627 2.786 ENSMUST00000042517.6
Fam169a
family with sequence similarity 169, member A
chr17_-_35909626 2.782 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr9_-_44920698 2.780 ENSMUST00000043675.7
Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr11_-_69920581 2.769 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr5_-_67815852 2.760 ENSMUST00000141443.1
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr4_+_123183456 2.729 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chrX_+_134404780 2.727 ENSMUST00000113224.2
ENSMUST00000113226.1
Drp2

dystrophin related protein 2

chr12_+_4082574 2.716 ENSMUST00000020986.7
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr16_-_37654408 2.672 ENSMUST00000023514.3
Ndufb4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr1_-_171222508 2.664 ENSMUST00000005817.2
Tomm40l
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr18_+_6332587 2.650 ENSMUST00000097682.2
Rpl27-ps3
ribosomal protein L27, pseudogene 3
chr2_+_164785823 2.635 ENSMUST00000174070.1
ENSMUST00000172577.1
ENSMUST00000056181.6
Snx21


sorting nexin family member 21


chr6_+_39592569 2.635 ENSMUST00000135671.1
ENSMUST00000119379.1
Ndufb2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2

chr17_+_34135182 2.595 ENSMUST00000042121.9
H2-DMa
histocompatibility 2, class II, locus DMa
chr5_+_66968559 2.588 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chrX_+_134404543 2.582 ENSMUST00000113228.1
ENSMUST00000153424.1
Drp2

dystrophin related protein 2

chr10_-_80855187 2.578 ENSMUST00000035775.8
Lsm7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_+_66968416 2.574 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr19_-_5366285 2.560 ENSMUST00000170010.1
Banf1
barrier to autointegration factor 1
chr1_-_4785671 2.542 ENSMUST00000130201.1
ENSMUST00000156816.1
Mrpl15

mitochondrial ribosomal protein L15

chr7_-_105574324 2.509 ENSMUST00000081165.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr7_-_24972685 2.488 ENSMUST00000076961.7
Rabac1
Rab acceptor 1 (prenylated)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 18.6 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
3.7 11.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
3.3 9.9 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510)
3.2 9.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
2.9 8.6 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
2.4 7.2 GO:0006106 fumarate metabolic process(GO:0006106)
2.3 7.0 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
2.3 6.8 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
2.2 6.7 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
2.1 6.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
2.0 6.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
2.0 6.0 GO:0019043 establishment of viral latency(GO:0019043)
1.9 17.2 GO:0071420 cellular response to histamine(GO:0071420)
1.9 7.6 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
1.8 8.9 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
1.7 1.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
1.6 12.6 GO:0019388 galactose catabolic process(GO:0019388)
1.6 22.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
1.5 6.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.5 4.6 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
1.5 13.8 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
1.5 19.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
1.5 8.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.4 4.1 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
1.3 2.6 GO:0002636 positive regulation of germinal center formation(GO:0002636)
1.3 3.8 GO:0098886 modification of dendritic spine(GO:0098886)
1.2 13.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.2 4.6 GO:1990379 lipid transport across blood brain barrier(GO:1990379)
1.1 5.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.1 8.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.1 4.2 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
1.0 27.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
1.0 9.0 GO:0038203 TORC2 signaling(GO:0038203)
1.0 4.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.9 4.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.9 2.8 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.9 5.6 GO:0046103 inosine biosynthetic process(GO:0046103)
0.9 7.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.9 2.8 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.9 2.7 GO:0045204 MAPK export from nucleus(GO:0045204)
0.9 5.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.8 5.9 GO:0006102 isocitrate metabolic process(GO:0006102)
0.8 4.0 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.8 2.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.8 3.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.8 1.5 GO:0019046 release from viral latency(GO:0019046)
0.8 5.3 GO:0090234 cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234)
0.7 0.7 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.7 16.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.7 2.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 2.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.7 2.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.7 3.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.7 2.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.6 5.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.6 1.9 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.6 5.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.6 9.3 GO:0007220 Notch receptor processing(GO:0007220)
0.6 11.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.6 9.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.6 1.9 GO:0097274 urea homeostasis(GO:0097274)
0.6 2.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.6 4.9 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.6 8.8 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.6 3.5 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.6 2.9 GO:0051012 microtubule sliding(GO:0051012)
0.6 2.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.6 1.7 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.6 3.9 GO:0009249 protein lipoylation(GO:0009249)
0.5 1.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.5 1.6 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.5 19.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.5 1.0 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.5 2.5 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.5 26.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.5 2.8 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 6.7 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.4 3.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.4 1.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.4 1.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.4 2.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4 2.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.4 1.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.4 1.6 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.4 3.6 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.4 3.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4 1.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.4 1.2 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.4 4.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 2.8 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 3.5 GO:0009644 response to high light intensity(GO:0009644)
0.4 9.2 GO:0051764 actin crosslink formation(GO:0051764)
0.4 1.5 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.4 9.9 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.4 1.1 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 2.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 1.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.4 1.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 2.1 GO:0051665 membrane raft localization(GO:0051665)
0.4 1.1 GO:0035672 regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672)
0.3 5.2 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.3 2.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.3 3.8 GO:0034982 mitochondrial protein processing(GO:0034982)
0.3 1.0 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.3 11.8 GO:0014003 oligodendrocyte development(GO:0014003)
0.3 1.0 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.3 1.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 3.2 GO:0031000 response to caffeine(GO:0031000)
0.3 0.6 GO:0060166 olfactory pit development(GO:0060166)
0.3 2.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.3 4.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.3 23.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.3 18.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.3 0.9 GO:2000612 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) kidney rudiment formation(GO:0072003) kidney field specification(GO:0072004) positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.3 5.5 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.3 2.6 GO:0016198 axon choice point recognition(GO:0016198)
0.3 6.1 GO:0071625 vocalization behavior(GO:0071625)
0.3 1.4 GO:0034214 protein hexamerization(GO:0034214)
0.3 2.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 1.1 GO:0018343 protein farnesylation(GO:0018343)
0.3 0.8 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.3 5.0 GO:0034389 lipid particle organization(GO:0034389)
0.3 4.5 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 0.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 1.6 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.3 5.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.3 6.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 1.8 GO:0061718 NADH regeneration(GO:0006735) positive regulation of immunoglobulin secretion(GO:0051024) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 2.3 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.2 2.0 GO:0090336 response to muscle activity(GO:0014850) positive regulation of brown fat cell differentiation(GO:0090336)
0.2 0.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.7 GO:0072384 organelle transport along microtubule(GO:0072384)
0.2 1.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 1.6 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 1.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 0.4 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 2.0 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 0.6 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.2 0.8 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 0.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 3.9 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.2 2.3 GO:0051683 establishment of Golgi localization(GO:0051683)
0.2 16.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 2.0 GO:0031639 plasminogen activation(GO:0031639)
0.2 3.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.2 4.5 GO:0097320 membrane tubulation(GO:0097320)
0.2 3.0 GO:0000338 protein deneddylation(GO:0000338)
0.2 3.2 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.2 15.3 GO:0032091 negative regulation of protein binding(GO:0032091)
0.2 0.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.2 1.1 GO:0061615 glycolytic process through fructose-6-phosphate(GO:0061615)
0.2 5.0 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2 0.5 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.2 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.2 3.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.8 GO:0015671 oxygen transport(GO:0015671)
0.2 1.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 0.3 GO:0071649 negative regulation of mitochondrial fusion(GO:0010637) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.1 0.4 GO:1901096 regulation of autophagosome maturation(GO:1901096) negative regulation of autophagosome maturation(GO:1901097)
0.1 3.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 1.5 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.7 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) choline metabolic process(GO:0019695)
0.1 5.9 GO:0009060 aerobic respiration(GO:0009060)
0.1 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.7 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 3.6 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:0043691 high-density lipoprotein particle remodeling(GO:0034375) reverse cholesterol transport(GO:0043691)
0.1 0.4 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 4.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 2.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.8 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 1.1 GO:0032225 regulation of synaptic transmission, dopaminergic(GO:0032225)
0.1 4.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.3 GO:0042026 protein refolding(GO:0042026)
0.1 3.7 GO:0045471 response to ethanol(GO:0045471)
0.1 0.3 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 1.4 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 0.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 2.4 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 0.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.1 0.9 GO:0031118 rRNA pseudouridine synthesis(GO:0031118) tRNA pseudouridine synthesis(GO:0031119)
0.1 3.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.6 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 3.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.9 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.1 1.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 4.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 7.3 GO:0007612 learning(GO:0007612)
0.1 0.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.8 GO:0051601 exocyst localization(GO:0051601)
0.1 6.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.5 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.8 GO:1990173 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 0.2 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.1 3.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.5 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.2 GO:2000189 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) positive regulation of cholesterol homeostasis(GO:2000189)
0.1 2.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 2.3 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 2.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:0002385 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.1 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 3.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 5.1 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 1.9 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 1.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 1.9 GO:0030317 sperm motility(GO:0030317)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.5 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.6 GO:0000012 single strand break repair(GO:0000012)
0.0 0.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.1 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 1.1 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.3 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 4.4 GO:0050808 synapse organization(GO:0050808)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.9 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 1.8 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 4.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.5 GO:1903541 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.4 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 2.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.7 GO:0051099 positive regulation of binding(GO:0051099)
0.0 0.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:0001707 mesoderm formation(GO:0001707)
0.0 0.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0098855 HCN channel complex(GO:0098855)
2.4 7.3 GO:1990075 periciliary membrane compartment(GO:1990075)
1.9 28.9 GO:1902711 GABA-A receptor complex(GO:1902711)
1.7 6.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
1.6 12.9 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
1.4 14.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
1.4 22.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
1.3 4.0 GO:0005940 septin ring(GO:0005940)
1.3 11.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.3 2.5 GO:1990812 growth cone filopodium(GO:1990812)
1.2 7.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
1.2 3.6 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.1 20.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.1 12.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.0 4.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.0 9.5 GO:0032426 stereocilium tip(GO:0032426)
0.9 14.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.8 3.8 GO:0097444 spine apparatus(GO:0097444)
0.7 5.6 GO:0001520 outer dense fiber(GO:0001520)
0.7 9.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.7 3.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.6 6.4 GO:0071439 clathrin complex(GO:0071439)
0.6 3.8 GO:0005859 muscle myosin complex(GO:0005859)
0.6 3.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 9.0 GO:0031932 TORC2 complex(GO:0031932)
0.6 1.7 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.5 5.7 GO:0005688 U6 snRNP(GO:0005688)
0.5 3.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 8.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 6.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.4 1.8 GO:0032280 symmetric synapse(GO:0032280)
0.4 1.8 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 1.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 2.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.4 1.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.4 19.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 1.5 GO:0005745 m-AAA complex(GO:0005745)
0.4 4.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 0.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 1.5 GO:0008091 spectrin(GO:0008091)
0.3 4.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 5.0 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3 0.6 GO:0016939 kinesin II complex(GO:0016939)
0.3 4.5 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.3 7.8 GO:0030137 COPI-coated vesicle(GO:0030137)
0.3 2.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 3.6 GO:0097449 astrocyte projection(GO:0097449)
0.3 1.1 GO:0070069 cytochrome complex(GO:0070069)
0.3 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 2.5 GO:0042587 glycogen granule(GO:0042587)
0.3 19.0 GO:0009925 basal plasma membrane(GO:0009925)
0.3 35.9 GO:0043204 perikaryon(GO:0043204)
0.3 1.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 2.8 GO:0005642 annulate lamellae(GO:0005642)
0.2 5.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 4.2 GO:0033268 node of Ranvier(GO:0033268)
0.2 1.6 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
0.2 2.0 GO:0097427 microtubule bundle(GO:0097427)
0.2 0.9 GO:0008537 proteasome activator complex(GO:0008537)
0.2 2.1 GO:0032009 early phagosome(GO:0032009)
0.2 2.5 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.2 10.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.4 GO:0030057 desmosome(GO:0030057)
0.2 2.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 6.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 1.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 9.9 GO:0030018 Z disc(GO:0030018)
0.1 2.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 13.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.5 GO:0001533 cornified envelope(GO:0001533)
0.1 10.3 GO:0005604 basement membrane(GO:0005604)
0.1 11.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 1.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 2.8 GO:0002102 podosome(GO:0002102)
0.1 1.0 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 3.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.7 GO:1904115 axon cytoplasm(GO:1904115)
0.1 7.1 GO:0005769 early endosome(GO:0005769)
0.1 1.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 3.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.8 GO:0005833 hemoglobin complex(GO:0005833)
0.1 7.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 4.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 1.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.2 GO:0032437 cuticular plate(GO:0032437)
0.1 8.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.1 1.7 GO:0031526 brush border membrane(GO:0031526)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.4 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 2.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 3.0 GO:0008180 COP9 signalosome(GO:0008180)
0.1 4.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.8 GO:0005832 zona pellucida receptor complex(GO:0002199) chaperonin-containing T-complex(GO:0005832)
0.1 2.0 GO:0031941 filamentous actin(GO:0031941)
0.1 3.5 GO:0016605 PML body(GO:0016605)
0.1 6.2 GO:0016324 apical plasma membrane(GO:0016324)
0.1 10.0 GO:0043209 myelin sheath(GO:0043209)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 9.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.4 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0000145 exocyst(GO:0000145)
0.1 2.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 57.2 GO:0030054 cell junction(GO:0030054)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.6 GO:0043679 axon terminus(GO:0043679)
0.0 1.0 GO:0044432 endoplasmic reticulum part(GO:0044432)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0005903 brush border(GO:0005903)
0.0 2.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 29.8 GO:0004111 creatine kinase activity(GO:0004111)
3.7 11.2 GO:0031403 lithium ion binding(GO:0031403)
3.7 22.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
3.2 12.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
3.2 9.5 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
3.0 12.0 GO:0001847 opsonin receptor activity(GO:0001847)
2.8 19.8 GO:0015198 oligopeptide transporter activity(GO:0015198)
2.6 12.9 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
2.3 13.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) mercury ion binding(GO:0045340)
2.1 10.3 GO:0043532 angiostatin binding(GO:0043532)
2.0 7.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.9 5.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
1.9 7.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.8 12.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.7 5.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
1.7 5.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.5 4.6 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.5 12.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.2 8.1 GO:0015288 porin activity(GO:0015288)
1.1 16.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.1 18.2 GO:0004890 GABA-A receptor activity(GO:0004890)
1.1 5.3 GO:0034235 GPI anchor binding(GO:0034235)
1.0 6.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.0 6.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.9 20.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.9 2.8 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.9 2.7 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.9 2.7 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.9 5.3 GO:0033142 progesterone receptor binding(GO:0033142)
0.9 15.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.9 3.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.9 6.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.9 3.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.8 7.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.8 3.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.8 9.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.8 3.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.7 4.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.7 4.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.7 4.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 8.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.7 2.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.7 2.0 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.6 3.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.6 2.5 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.6 14.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.6 1.8 GO:0030172 troponin C binding(GO:0030172)
0.6 2.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.6 1.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.5 11.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.5 2.1 GO:0019808 polyamine binding(GO:0019808)
0.5 3.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.5 7.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 2.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.5 3.4 GO:0015266 protein channel activity(GO:0015266)
0.5 2.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.5 4.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.4 10.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 8.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 12.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 3.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4 6.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.4 4.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 1.7 GO:0035586 purinergic receptor activity(GO:0035586)
0.4 2.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4 4.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.4 3.9 GO:0050811 GABA receptor binding(GO:0050811)
0.4 2.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 6.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 1.0 GO:0035939 microsatellite binding(GO:0035939)
0.3 6.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 0.9 GO:0042895 antibiotic transporter activity(GO:0042895)
0.3 1.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 0.8 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.3 1.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 3.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 2.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 1.6 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.3 6.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 1.1 GO:0004064 arylesterase activity(GO:0004064)
0.3 2.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 5.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.3 4.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.3 3.3 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 1.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 6.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 4.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 7.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 9.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 6.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 3.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 0.8 GO:0004104 choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.2 0.8 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 5.0 GO:0070064 proline-rich region binding(GO:0070064)
0.2 4.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.8 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.6 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.2 0.6 GO:0016015 morphogen activity(GO:0016015)
0.2 3.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.2 0.6 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.2 0.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.2 0.7 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 11.5 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.2 0.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 38.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 2.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 1.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 6.2 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 4.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 7.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 5.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.5 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 2.1 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.1 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 0.5 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 1.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 7.0 GO:0030507 spectrin binding(GO:0030507)
0.1 3.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 3.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.7 GO:0048039 ubiquinone binding(GO:0048039)
0.1 4.3 GO:0005112 Notch binding(GO:0005112)
0.1 2.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 4.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.4 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 3.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 7.7 GO:0005518 collagen binding(GO:0005518)
0.1 1.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 3.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.4 GO:0008483 transaminase activity(GO:0008483)
0.1 15.5 GO:0030246 carbohydrate binding(GO:0030246)
0.1 0.7 GO:0051117 ATPase binding(GO:0051117)
0.1 4.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.8 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 2.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 2.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.1 GO:0050692 DBD domain binding(GO:0050692)
0.1 11.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 4.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 4.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.5 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 2.1 GO:0019003 GDP binding(GO:0019003)
0.0 5.7 GO:0008168 methyltransferase activity(GO:0008168)
0.0 1.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.1 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 5.2 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.6 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.4 GO:0003924 GTPase activity(GO:0003924)
0.0 4.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 1.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 22.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.8 32.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.4 5.3 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.3 3.2 PID_ALK2_PATHWAY ALK2 signaling events
0.2 9.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 7.0 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 12.3 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.2 22.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 7.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 10.4 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 4.3 PID_ARF_3PATHWAY Arf1 pathway
0.1 11.0 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 2.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.1 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.8 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.7 PID_IGF1_PATHWAY IGF1 pathway
0.1 0.9 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 1.8 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 1.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.0 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.7 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 1.5 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 1.1 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.8 PID_FGF_PATHWAY FGF signaling pathway
0.0 2.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.2 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.5 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.3 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID_ENDOTHELIN_PATHWAY Endothelins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 19.8 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
1.8 22.0 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
1.8 28.5 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
1.4 11.0 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.2 41.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
1.2 21.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
1.2 15.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 17.5 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.6 43.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.6 12.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.6 7.8 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.5 4.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.5 24.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.4 3.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 4.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.4 15.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 5.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 15.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.4 4.7 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4 9.4 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.3 7.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.3 3.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 6.8 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.2 9.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 16.3 REACTOME_SIGNALING_BY_NOTCH1 Genes involved in Signaling by NOTCH1
0.2 3.4 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 12.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 2.1 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.2 6.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.2 2.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 4.6 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 5.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 3.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 11.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 2.9 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 5.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 3.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.8 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.0 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.0 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 2.3 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1 5.5 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 2.0 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.0 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 2.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 4.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.7 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 0.5 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.0 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.3 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.7 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.1 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.8 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.5 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 4.3 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.9 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.3 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 0.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 2.4 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions