Motif ID: Etv4

Z-value: 0.863


Transcription factors associated with Etv4:

Gene SymbolEntrez IDGene Name
Etv4 ENSMUSG00000017724.8 Etv4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv4mm10_v2_chr11_-_101785252_1017853710.445.9e-05Click!


Activity profile for motif Etv4.

activity profile for motif Etv4


Sorted Z-values histogram for motif Etv4

Sorted Z-values for motif Etv4



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66969616 13.839 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr6_+_5725639 12.950 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr9_+_107935876 11.702 ENSMUST00000035700.8
Camkv
CaM kinase-like vesicle-associated
chr15_-_66812593 11.181 ENSMUST00000100572.3
Sla
src-like adaptor
chr9_-_29411736 9.832 ENSMUST00000115236.1
Ntm
neurotrimin
chr17_-_56133817 9.308 ENSMUST00000167545.1
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr13_+_83504032 9.292 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr3_+_95526777 8.856 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr11_-_76509419 7.722 ENSMUST00000094012.4
Abr
active BCR-related gene
chr1_-_56969864 7.550 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_56969827 7.431 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr8_+_70501116 7.390 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr6_+_8259288 7.273 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr7_+_45627482 6.922 ENSMUST00000057927.7
Rasip1
Ras interacting protein 1
chr7_+_30413744 6.634 ENSMUST00000032800.9
Tyrobp
TYRO protein tyrosine kinase binding protein
chr9_-_29412204 5.981 ENSMUST00000115237.1
Ntm
neurotrimin
chr2_+_14229390 5.727 ENSMUST00000028045.2
Mrc1
mannose receptor, C type 1
chr13_-_49309217 5.717 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr3_-_141982224 5.657 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr9_+_56418624 5.559 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr18_+_30272747 5.445 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
Pik3c3


phosphoinositide-3-kinase, class 3


chr2_-_5714490 5.432 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr17_+_3397189 5.252 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr13_+_109632760 5.176 ENSMUST00000135275.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr14_-_76556662 4.939 ENSMUST00000064517.7
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr13_-_37049203 4.814 ENSMUST00000037491.8
F13a1
coagulation factor XIII, A1 subunit
chr7_+_49246131 4.754 ENSMUST00000064395.6
Nav2
neuron navigator 2
chr9_-_110476637 4.692 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr1_-_191318090 4.689 ENSMUST00000046770.9
Nenf
neuron derived neurotrophic factor
chr19_-_57360668 4.593 ENSMUST00000181921.1
B230217O12Rik
RIKEN cDNA B230217O12 gene
chr11_+_103171081 4.507 ENSMUST00000042286.5
Fmnl1
formin-like 1
chr11_-_48816936 4.495 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr7_+_73740277 4.491 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr11_-_48817332 4.474 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr11_-_45944910 4.452 ENSMUST00000129820.1
Lsm11
U7 snRNP-specific Sm-like protein LSM11
chr18_+_23803962 4.434 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr4_+_103313806 4.348 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr11_+_101245996 4.333 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr11_-_59163281 4.243 ENSMUST00000069631.2
Iba57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr11_+_101246405 4.219 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr17_+_55445550 4.171 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr2_+_130405256 4.163 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr6_+_125552948 4.037 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr17_+_74489492 3.904 ENSMUST00000024873.6
Yipf4
Yip1 domain family, member 4
chr6_+_8259327 3.869 ENSMUST00000159378.1
Gm16039
predicted gene 16039
chr6_-_99028251 3.851 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
Foxp1



forkhead box P1



chr15_+_25984359 3.780 ENSMUST00000061875.6
Zfp622
zinc finger protein 622
chr8_+_105326354 3.713 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chr17_-_24527830 3.609 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr15_+_30172570 3.541 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr8_+_94037198 3.512 ENSMUST00000109556.2
ENSMUST00000093301.2
ENSMUST00000060632.7
Ogfod1


2-oxoglutarate and iron-dependent oxygenase domain containing 1


chr13_-_92030897 3.508 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr13_-_91388079 3.451 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr9_+_58582240 3.442 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr5_+_122391878 3.366 ENSMUST00000102525.4
Arpc3
actin related protein 2/3 complex, subunit 3
chr2_-_57113053 3.361 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr2_+_127336152 3.324 ENSMUST00000028846.6
Dusp2
dual specificity phosphatase 2
chr3_-_109027600 3.319 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chr12_-_84970814 3.290 ENSMUST00000165886.1
ENSMUST00000167448.1
ENSMUST00000043169.7
Arel1


apoptosis resistant E3 ubiquitin protein ligase 1


chr3_+_123267445 3.275 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr17_-_24527925 3.256 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr15_-_79804717 3.253 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr11_-_105944412 3.235 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
Cyb561


cytochrome b-561


chr11_+_82035569 3.206 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr9_+_108290433 3.186 ENSMUST00000035227.6
Nicn1
nicolin 1
chr12_-_67221221 3.157 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr11_+_74898078 3.153 ENSMUST00000045807.7
Tsr1
TSR1 20S rRNA accumulation
chr6_-_124741374 3.107 ENSMUST00000004389.5
Grcc10
gene rich cluster, C10 gene
chr6_+_17463749 3.105 ENSMUST00000115443.1
Met
met proto-oncogene
chr2_-_84678051 3.084 ENSMUST00000053664.8
ENSMUST00000111664.1
Tmx2

thioredoxin-related transmembrane protein 2

chr4_-_129573637 3.081 ENSMUST00000102596.1
Lck
lymphocyte protein tyrosine kinase
chr6_+_8259379 3.049 ENSMUST00000162034.1
ENSMUST00000160705.1
ENSMUST00000159433.1
Gm16039


predicted gene 16039


chr17_+_8311101 3.047 ENSMUST00000154553.1
Sft2d1
SFT2 domain containing 1
chr5_+_117133567 3.030 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
Taok3


TAO kinase 3


chr2_+_4559742 2.981 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr16_-_4880284 2.973 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr10_-_89732253 2.959 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr14_-_65953728 2.950 ENSMUST00000042046.3
Scara3
scavenger receptor class A, member 3
chr17_+_33940660 2.904 ENSMUST00000025170.9
Wdr46
WD repeat domain 46
chr16_+_18811772 2.903 ENSMUST00000168822.1
ENSMUST00000115578.3
Ufd1l

ubiquitin fusion degradation 1 like

chr18_+_37473538 2.882 ENSMUST00000050034.1
Pcdhb15
protocadherin beta 15
chr7_+_80261202 2.864 ENSMUST00000117989.1
Ngrn
neugrin, neurite outgrowth associated
chr7_+_29309429 2.828 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr6_-_22356068 2.822 ENSMUST00000163963.1
ENSMUST00000165576.1
Fam3c

family with sequence similarity 3, member C

chr2_+_168230597 2.806 ENSMUST00000099071.3
Mocs3
molybdenum cofactor synthesis 3
chr10_+_79988584 2.806 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr4_+_43562672 2.805 ENSMUST00000167751.1
ENSMUST00000132631.1
Creb3

cAMP responsive element binding protein 3

chr9_+_58582397 2.805 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr6_-_22356176 2.788 ENSMUST00000081288.7
Fam3c
family with sequence similarity 3, member C
chr9_-_40346290 2.775 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chrX_+_159840463 2.762 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr1_-_124045247 2.719 ENSMUST00000112603.2
Dpp10
dipeptidylpeptidase 10
chr8_+_85071737 2.677 ENSMUST00000078665.6
Dhps
deoxyhypusine synthase
chr17_+_29268788 2.676 ENSMUST00000064709.5
ENSMUST00000120346.1
BC004004

cDNA sequence BC004004

chr2_+_84678396 2.623 ENSMUST00000102645.3
Med19
mediator of RNA polymerase II transcription, subunit 19 homolog (yeast)
chr5_-_103100054 2.611 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr11_+_70647258 2.574 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr6_+_17463826 2.548 ENSMUST00000140070.1
Met
met proto-oncogene
chr3_-_50443603 2.545 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr3_-_89773221 2.535 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr17_-_80290476 2.510 ENSMUST00000086555.3
ENSMUST00000038166.7
Dhx57

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

chr3_+_82358056 2.482 ENSMUST00000091014.4
Map9
microtubule-associated protein 9
chr1_+_87620334 2.474 ENSMUST00000042275.8
ENSMUST00000168783.1
Inpp5d

inositol polyphosphate-5-phosphatase D

chr15_+_103453782 2.423 ENSMUST00000047405.7
Nckap1l
NCK associated protein 1 like
chr4_+_156235999 2.422 ENSMUST00000179543.1
ENSMUST00000179886.1
Noc2l

nucleolar complex associated 2 homolog (S. cerevisiae)

chr14_-_19977249 2.414 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr17_-_33940299 2.407 ENSMUST00000173363.1
ENSMUST00000174048.1
ENSMUST00000179418.1
ENSMUST00000174426.1
ENSMUST00000025163.7
H2-Ke2




H2-K region expressed gene 2




chr15_+_78597047 2.379 ENSMUST00000043069.5
Cyth4
cytohesin 4
chr17_-_46680870 2.358 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3

kelch domain containing 3

chrX_+_162760388 2.355 ENSMUST00000033720.5
ENSMUST00000112327.1
Rbbp7

retinoblastoma binding protein 7

chr3_-_8964037 2.347 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr1_-_124045523 2.341 ENSMUST00000112606.1
Dpp10
dipeptidylpeptidase 10
chr14_-_74947865 2.333 ENSMUST00000088970.5
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chrX_+_153832225 2.310 ENSMUST00000148708.1
ENSMUST00000123264.1
ENSMUST00000049999.8
Spin2c


spindlin family, member 2C


chr16_-_94526830 2.302 ENSMUST00000023615.6
Dscr3
Down syndrome critical region gene 3
chr4_-_122885965 2.301 ENSMUST00000128485.1
Cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr11_+_83302641 2.296 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr7_+_97081711 2.288 ENSMUST00000004622.5
Gab2
growth factor receptor bound protein 2-associated protein 2
chr13_+_109260481 2.271 ENSMUST00000153234.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr8_-_105295934 2.258 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr11_+_97362396 2.256 ENSMUST00000045540.3
Socs7
suppressor of cytokine signaling 7
chr11_-_70646972 2.245 ENSMUST00000014750.8
Slc25a11
solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
chr10_-_34207551 2.238 ENSMUST00000048010.7
Dse
dermatan sulfate epimerase
chr11_+_61653259 2.226 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr6_+_142413441 2.221 ENSMUST00000088263.4
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr17_+_46681038 2.214 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chr7_-_113347273 2.213 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr1_+_152399824 2.202 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr9_-_107541816 2.191 ENSMUST00000041459.3
Cyb561d2
cytochrome b-561 domain containing 2
chr19_-_53944621 2.181 ENSMUST00000135402.2
Bbip1
BBSome interacting protein 1
chr15_-_100403243 2.149 ENSMUST00000124324.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr14_-_6287250 2.132 ENSMUST00000170104.2
Gm3411
predicted gene 3411
chr12_-_27160311 2.130 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr16_+_29579331 2.128 ENSMUST00000160597.1
Opa1
optic atrophy 1
chr11_-_102156339 2.119 ENSMUST00000021296.6
Tmem101
transmembrane protein 101
chr13_-_100730839 2.118 ENSMUST00000091299.6
Cdk7
cyclin-dependent kinase 7
chr11_+_49244191 2.095 ENSMUST00000167400.1
ENSMUST00000081794.6
Mgat1

mannoside acetylglucosaminyltransferase 1

chr17_+_35135196 2.072 ENSMUST00000172571.1
ENSMUST00000173491.1
Bag6

BCL2-associated athanogene 6

chr11_-_102469839 2.071 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr11_-_120573253 2.067 ENSMUST00000026122.4
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr7_-_122067263 2.019 ENSMUST00000033159.3
Ears2
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr4_+_138304723 2.005 ENSMUST00000030538.4
Ddost
dolichyl-di-phosphooligosaccharide-protein glycotransferase
chr16_+_36934976 1.992 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr17_+_33955902 1.988 ENSMUST00000173196.2
Vps52
vacuolar protein sorting 52 (yeast)
chr17_+_34031787 1.982 ENSMUST00000044858.8
Rxrb
retinoid X receptor beta
chr14_+_80000292 1.980 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chrX_-_157492280 1.979 ENSMUST00000112529.1
Sms
spermine synthase
chr18_+_24470844 1.978 ENSMUST00000097646.3
2700062C07Rik
RIKEN cDNA 2700062C07 gene
chr15_-_64382736 1.972 ENSMUST00000176384.1
ENSMUST00000175799.1
Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

chr5_-_118244861 1.953 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr11_+_87592145 1.948 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr1_+_152807877 1.942 ENSMUST00000027754.6
Ncf2
neutrophil cytosolic factor 2
chr14_-_19977151 1.929 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr11_-_79530569 1.926 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
Evi2a

Evi2b
ecotropic viral integration site 2a

ecotropic viral integration site 2b
chr10_-_63927434 1.925 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr3_+_88043098 1.908 ENSMUST00000166021.1
ENSMUST00000029707.7
Gpatch4

G patch domain containing 4

chr17_+_35135174 1.905 ENSMUST00000166426.2
ENSMUST00000025250.7
Bag6

BCL2-associated athanogene 6

chr2_-_7395879 1.888 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr2_+_91650169 1.882 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr1_+_171329015 1.882 ENSMUST00000111300.1
Dedd
death effector domain-containing
chr8_-_71723308 1.881 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr5_-_34187670 1.881 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr17_+_33955812 1.880 ENSMUST00000025178.9
ENSMUST00000114330.2
Vps52

vacuolar protein sorting 52 (yeast)

chr3_-_87768932 1.875 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
Pear1




platelet endothelial aggregation receptor 1




chr1_-_52817643 1.871 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr13_-_23710714 1.869 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr9_+_107551516 1.868 ENSMUST00000093786.2
ENSMUST00000122225.1
Rassf1

Ras association (RalGDS/AF-6) domain family member 1

chr2_+_91096744 1.865 ENSMUST00000132741.2
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr15_-_64382908 1.853 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
Asap1



ArfGAP with SH3 domain, ankyrin repeat and PH domain1



chr6_-_99096196 1.846 ENSMUST00000175886.1
Foxp1
forkhead box P1
chr14_-_19977040 1.818 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr6_+_86849488 1.817 ENSMUST00000089519.6
ENSMUST00000113668.1
Aak1

AP2 associated kinase 1

chr11_+_83302817 1.806 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr17_+_26252915 1.804 ENSMUST00000114976.2
ENSMUST00000140427.1
ENSMUST00000119928.1
Luc7l


Luc7 homolog (S. cerevisiae)-like


chr4_-_156228540 1.803 ENSMUST00000105571.2
Plekhn1
pleckstrin homology domain containing, family N member 1
chr6_-_124738579 1.791 ENSMUST00000174265.1
ENSMUST00000004377.8
Ptpn6

protein tyrosine phosphatase, non-receptor type 6

chr11_-_109722214 1.781 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr14_-_55671873 1.780 ENSMUST00000163750.1
ENSMUST00000010520.8
Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr9_-_20952838 1.775 ENSMUST00000004202.9
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr10_+_81357491 1.770 ENSMUST00000044844.8
Mfsd12
major facilitator superfamily domain containing 12
chr2_+_39008076 1.758 ENSMUST00000112862.1
ENSMUST00000090993.5
Arpc5l

actin related protein 2/3 complex, subunit 5-like

chr17_+_24414640 1.755 ENSMUST00000115371.1
ENSMUST00000088512.5
ENSMUST00000163717.1
Rnps1


ribonucleic acid binding protein S1


chr18_+_36760214 1.754 ENSMUST00000049323.7
Wdr55
WD repeat domain 55
chr1_-_52817503 1.742 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr12_+_87266696 1.741 ENSMUST00000021425.6
Ahsa1
AHA1, activator of heat shock protein ATPase 1
chr6_-_128124312 1.739 ENSMUST00000127105.1
Tspan9
tetraspanin 9
chr11_+_29692937 1.726 ENSMUST00000102843.3
ENSMUST00000102842.3
ENSMUST00000078830.4
ENSMUST00000170731.1
Rtn4



reticulon 4



chr16_+_29579347 1.711 ENSMUST00000038867.6
ENSMUST00000161186.1
Opa1

optic atrophy 1

chr6_+_125009232 1.701 ENSMUST00000112428.1
Zfp384
zinc finger protein 384
chr7_-_143600049 1.700 ENSMUST00000105909.3
ENSMUST00000010899.7
Cars

cysteinyl-tRNA synthetase

chr15_+_78983041 1.694 ENSMUST00000109687.1
ENSMUST00000109688.1
ENSMUST00000130663.2
Triobp


TRIO and F-actin binding protein


chr7_+_46796088 1.670 ENSMUST00000006774.4
ENSMUST00000165031.1
Gtf2h1

general transcription factor II H, polypeptide 1

chr11_-_59163696 1.670 ENSMUST00000137433.1
ENSMUST00000054523.5
Iba57

IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)

chr11_-_115276973 1.664 ENSMUST00000021078.2
Fdxr
ferredoxin reductase
chr1_+_16688405 1.646 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr13_-_102906046 1.645 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr14_-_55722176 1.642 ENSMUST00000169237.1
ENSMUST00000062861.7
Rabggta

Rab geranylgeranyl transferase, a subunit

chr3_-_106790143 1.642 ENSMUST00000038845.8
Cd53
CD53 antigen
chr5_+_117363513 1.633 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr11_-_20112876 1.622 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
1.8 5.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.6 4.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
1.5 7.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
1.4 8.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
1.4 5.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.3 3.9 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
1.2 6.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
1.2 7.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.2 4.8 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
1.2 13.0 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
1.2 13.0 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.2 4.6 GO:0014042 positive regulation of neuron maturation(GO:0014042)
1.1 6.6 GO:2001204 regulation of osteoclast development(GO:2001204)
1.1 3.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
1.1 8.5 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
1.0 3.1 GO:0061744 motor behavior(GO:0061744)
1.0 4.9 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.9 2.8 GO:0019046 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.9 3.7 GO:0006624 vacuolar protein processing(GO:0006624)
0.9 2.7 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.9 4.3 GO:0010637 diet induced thermogenesis(GO:0002024) negative regulation of mitochondrial fusion(GO:0010637)
0.8 3.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.8 2.5 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.8 5.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.8 5.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.8 3.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.7 2.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.7 3.7 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.7 2.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.7 9.4 GO:0010447 response to acidic pH(GO:0010447)
0.7 5.3 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.7 2.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.6 5.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 3.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 3.2 GO:2000427 eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683) positive regulation of apoptotic cell clearance(GO:2000427)
0.6 10.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.6 1.8 GO:0051715 cytolysis in other organism(GO:0051715)
0.6 6.0 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.6 1.8 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.6 7.4 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.6 5.7 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.6 5.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.5 6.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 1.6 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.5 2.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.5 1.6 GO:0002432 granuloma formation(GO:0002432)
0.5 2.0 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.5 2.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.5 0.9 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.5 1.4 GO:0070889 platelet alpha granule organization(GO:0070889)
0.5 1.4 GO:0019085 early viral transcription(GO:0019085)
0.5 4.5 GO:0051014 actin filament severing(GO:0051014)
0.4 3.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 2.7 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.4 1.8 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.4 0.9 GO:0019086 late viral transcription(GO:0019086)
0.4 3.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.4 2.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 2.1 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.4 4.7 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.4 3.0 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.4 1.2 GO:2001180 regulation of interleukin-18 production(GO:0032661) negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.4 1.6 GO:0002188 translation reinitiation(GO:0002188)
0.4 1.2 GO:1905072 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.4 0.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.4 0.8 GO:0045054 constitutive secretory pathway(GO:0045054)
0.4 1.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.4 1.9 GO:0045346 regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347)
0.4 1.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.4 1.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 0.3 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.3 2.7 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.3 1.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.3 1.3 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3 1.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 1.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 1.3 GO:0016240 autophagosome docking(GO:0016240)
0.3 5.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 1.3 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.3 1.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 2.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 0.9 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.3 0.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 1.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.3 0.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.5 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.3 1.2 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.3 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 2.0 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.3 2.9 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.3 1.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 1.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 1.7 GO:0070166 enamel mineralization(GO:0070166)
0.3 1.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.3 1.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.3 0.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 5.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 2.4 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.3 1.0 GO:0003356 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.3 1.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.3 3.6 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.3 1.8 GO:0006102 isocitrate metabolic process(GO:0006102)
0.3 2.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.3 2.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 3.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 3.2 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.2 2.9 GO:0070995 NADPH oxidation(GO:0070995)
0.2 1.5 GO:0032811 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811)
0.2 1.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 2.4 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 1.7 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.2 1.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 4.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 2.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 13.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 2.4 GO:0045730 respiratory burst(GO:0045730)
0.2 0.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 1.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.2 0.6 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.2 1.3 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 0.4 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.4 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.2 5.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.8 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.2 1.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 1.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.8 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 2.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 2.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 0.9 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.2 0.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 0.9 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 0.4 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.2 1.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 1.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 2.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 1.0 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 0.8 GO:0051665 membrane raft localization(GO:0051665)
0.2 1.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 1.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 1.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 3.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.6 GO:0090647 modulation of age-related behavioral decline(GO:0090647)
0.1 1.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 3.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 8.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.4 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.2 GO:0006544 glycine metabolic process(GO:0006544)
0.1 3.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.7 GO:0033600 positive regulation of exit from mitosis(GO:0031536) negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 2.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 3.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 3.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 3.1 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.1 0.9 GO:0006265 DNA topological change(GO:0006265)
0.1 2.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 3.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 1.2 GO:0008334 histone mRNA metabolic process(GO:0008334) histone mRNA catabolic process(GO:0071044)
0.1 0.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.7 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.3 GO:0044110 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.1 2.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.7 GO:0045116 protein neddylation(GO:0045116)
0.1 0.3 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 4.3 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) positive regulation of receptor catabolic process(GO:2000646)
0.1 0.6 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 1.9 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 1.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 1.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 1.2 GO:0001963 synaptic transmission, dopaminergic(GO:0001963)
0.1 0.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 7.0 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.8 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.7 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 0.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 1.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 4.6 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.4 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 1.4 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 3.6 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.3 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.1 1.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 12.0 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 0.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.7 GO:0030259 lipid glycosylation(GO:0030259)
0.1 3.3 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.9 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.5 GO:0072015 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.5 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 1.5 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.3 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.4 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.1 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 3.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 4.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 5.6 GO:0001570 vasculogenesis(GO:0001570)
0.1 7.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 2.1 GO:0001706 endoderm formation(GO:0001706)
0.1 0.3 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.4 GO:0002002 regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
0.1 2.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 1.0 GO:0007614 short-term memory(GO:0007614)
0.1 3.3 GO:0022900 electron transport chain(GO:0022900)
0.1 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 1.1 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.6 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.1 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 3.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 2.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:1901420 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0060686 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.0 0.2 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086)
0.0 0.4 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.1 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 2.6 GO:0007416 synapse assembly(GO:0007416)
0.0 0.3 GO:0006907 pinocytosis(GO:0006907)
0.0 0.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.7 GO:0001889 liver development(GO:0001889)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.2 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0071671 monocyte extravasation(GO:0035696) regulation of smooth muscle cell chemotaxis(GO:0071671) positive regulation of smooth muscle cell chemotaxis(GO:0071673) regulation of monocyte extravasation(GO:2000437)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.1 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.3 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.5 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 2.8 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.6 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.3 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.3 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
2.5 7.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.8 1.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.7 8.6 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.3 3.8 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
1.1 1.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.1 3.2 GO:0044299 C-fiber(GO:0044299)
0.9 2.8 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.9 2.6 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.8 4.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.8 4.0 GO:0005683 U7 snRNP(GO:0005683)
0.8 3.9 GO:1990745 EARP complex(GO:1990745)
0.8 5.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.7 2.1 GO:0070985 TFIIK complex(GO:0070985)
0.7 8.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.6 3.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.6 3.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.6 3.7 GO:0097443 sorting endosome(GO:0097443)
0.6 3.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 4.0 GO:0071439 clathrin complex(GO:0071439)
0.5 1.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.5 4.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.5 2.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.5 1.9 GO:1902636 kinociliary basal body(GO:1902636)
0.5 1.9 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.5 1.9 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.4 1.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.4 2.1 GO:0070826 paraferritin complex(GO:0070826)
0.4 2.5 GO:0000235 astral microtubule(GO:0000235)
0.4 1.9 GO:1990357 terminal web(GO:1990357)
0.4 1.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 3.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 1.3 GO:0001651 dense fibrillar component(GO:0001651)
0.3 0.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 4.8 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 1.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 0.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 2.4 GO:0000439 core TFIIH complex(GO:0000439)
0.3 9.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 7.4 GO:0031430 M band(GO:0031430)
0.3 3.3 GO:0031209 SCAR complex(GO:0031209)
0.2 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 2.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 1.9 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 6.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 1.1 GO:1990130 Iml1 complex(GO:1990130)
0.2 4.5 GO:0000242 pericentriolar material(GO:0000242)
0.2 2.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 2.2 GO:0034464 BBSome(GO:0034464)
0.2 1.8 GO:0061574 ASAP complex(GO:0061574)
0.2 0.8 GO:0002102 podosome(GO:0002102)
0.2 0.8 GO:0019034 viral replication complex(GO:0019034)
0.2 3.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.2 0.7 GO:0031673 H zone(GO:0031673)
0.2 2.0 GO:0005688 U6 snRNP(GO:0005688)
0.2 2.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 7.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 2.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.3 GO:0032009 early phagosome(GO:0032009)
0.2 6.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 19.0 GO:0031225 anchored component of membrane(GO:0031225)
0.2 22.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 3.6 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 1.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 3.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.8 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.8 GO:0070847 core mediator complex(GO:0070847)
0.1 0.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.4 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.0 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.4 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 2.8 GO:0071565 nBAF complex(GO:0071565)
0.1 0.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 3.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 3.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.4 GO:0016589 NURF complex(GO:0016589)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 6.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 2.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.2 GO:0030673 axolemma(GO:0030673)
0.1 0.6 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 5.4 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.1 1.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.1 GO:0031011 Ino80 complex(GO:0031011)
0.1 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.1 GO:0030008 TRAPP complex(GO:0030008)
0.1 5.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.2 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:0033391 chromatoid body(GO:0033391)
0.1 0.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 2.4 GO:0043209 myelin sheath(GO:0043209)
0.1 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 2.1 GO:0016592 mediator complex(GO:0016592)
0.1 0.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.7 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.9 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.8 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 1.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.0 GO:0055037 recycling endosome(GO:0055037)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 7.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 11.6 GO:0009986 cell surface(GO:0009986)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 2.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 1.4 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.0 GO:0030017 sarcomere(GO:0030017)
0.0 2.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 9.2 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.3 GO:0012506 vesicle membrane(GO:0012506)
0.0 0.3 GO:0005840 ribosome(GO:0005840)
0.0 3.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0030426 growth cone(GO:0030426)
0.0 1.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.6 GO:0097643 amylin receptor activity(GO:0097643)
1.5 4.5 GO:0071209 U7 snRNA binding(GO:0071209)
1.4 5.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.2 6.0 GO:0042610 CD8 receptor binding(GO:0042610)
1.2 4.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.1 4.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.1 3.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
1.1 7.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.9 3.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.8 4.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.8 3.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.8 3.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.8 3.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.8 13.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.7 2.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.7 3.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.7 4.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.7 2.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 2.5 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.6 5.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.6 2.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.6 6.0 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.6 1.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.6 5.8 GO:0019865 immunoglobulin binding(GO:0019865)
0.6 2.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.5 1.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.5 3.8 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.5 2.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.5 9.3 GO:0035198 miRNA binding(GO:0035198)
0.5 2.4 GO:0031493 nucleosomal histone binding(GO:0031493)
0.5 9.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 1.4 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.5 1.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.4 2.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4 2.1 GO:0070051 fibrinogen binding(GO:0070051)
0.4 5.3 GO:0015643 toxic substance binding(GO:0015643)
0.4 1.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.4 3.6 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.4 0.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 5.7 GO:0005537 mannose binding(GO:0005537)
0.4 15.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 2.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 4.5 GO:0005522 profilin binding(GO:0005522)
0.3 15.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 6.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 1.0 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.3 13.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 4.9 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.3 1.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3 1.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.3 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 1.9 GO:0051525 NFAT protein binding(GO:0051525)
0.3 2.1 GO:0000339 RNA cap binding(GO:0000339)
0.3 0.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 7.2 GO:0001968 fibronectin binding(GO:0001968)
0.3 2.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 7.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 1.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 0.8 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 1.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 0.5 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.3 1.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 0.8 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 3.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 2.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 4.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 4.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.7 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.2 1.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2 2.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 1.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.9 GO:0039706 co-receptor binding(GO:0039706)
0.2 4.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 0.8 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 0.6 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 1.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 0.6 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.2 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.7 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.2 2.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 0.5 GO:0030519 snoRNP binding(GO:0030519)
0.2 1.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 3.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 0.9 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.5 GO:0097677 STAT family protein binding(GO:0097677)
0.2 2.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 4.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0030172 troponin C binding(GO:0030172)
0.1 4.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 3.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.8 GO:0031489 myosin V binding(GO:0031489)
0.1 0.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 6.6 GO:0030507 spectrin binding(GO:0030507)
0.1 1.2 GO:0015266 protein channel activity(GO:0015266)
0.1 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 2.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 2.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.7 GO:0004673 protein histidine kinase activity(GO:0004673)
0.1 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 10.6 GO:0000149 SNARE binding(GO:0000149)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 4.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 6.0 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.7 GO:0070402 NADPH binding(GO:0070402)
0.1 0.4 GO:0035877 death effector domain binding(GO:0035877)
0.1 3.9 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 1.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 4.3 GO:0030276 clathrin binding(GO:0030276)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.2 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 1.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.3 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 5.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 1.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 2.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 2.7 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 4.9 GO:0008083 growth factor activity(GO:0008083)
0.1 7.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0008009 chemokine activity(GO:0008009)
0.1 6.0 GO:0008201 heparin binding(GO:0008201)
0.1 3.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.6 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.1 7.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.5 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 2.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.1 GO:0072542 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) protein phosphatase activator activity(GO:0072542)
0.0 2.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.9 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 2.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 1.2 GO:0020037 heme binding(GO:0020037)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.0 2.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 8.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.1 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.0 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.3 9.6 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.3 8.1 PID_ARF_3PATHWAY Arf1 pathway
0.3 6.4 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.3 6.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.3 9.9 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 4.5 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 2.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 4.8 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 2.1 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.2 1.9 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.2 10.9 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.2 1.6 PID_IL3_PATHWAY IL3-mediated signaling events
0.2 12.1 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.2 9.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.2 12.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.2 3.0 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 6.6 PID_BMP_PATHWAY BMP receptor signaling
0.1 0.7 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.1 1.8 PID_EPO_PATHWAY EPO signaling pathway
0.1 1.8 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 4.6 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 1.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 3.9 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 8.4 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 4.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.9 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 4.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 10.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.0 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 1.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 0.4 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.1 1.2 PID_ALK1_PATHWAY ALK1 signaling events
0.1 1.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 9.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.6 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 2.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.6 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 5.3 NABA_MATRISOME_ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.4 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.7 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.3 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.0 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.8 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID_MTOR_4PATHWAY mTOR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.8 4.8 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.6 9.3 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.5 4.6 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.5 6.0 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.4 8.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.4 5.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.3 9.1 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.3 10.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.3 4.7 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 2.6 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 6.6 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 6.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.2 6.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 1.5 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.2 1.9 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 1.6 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.2 2.0 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 4.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 7.2 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ Genes involved in Formation of RNA Pol II elongation complex
0.2 4.1 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.2 12.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 1.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 3.8 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.5 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 2.0 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 8.6 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.1 2.0 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.0 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 5.6 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.2 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.2 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.8 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.5 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 6.8 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 4.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.3 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 1.9 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 1.2 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.2 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 3.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.1 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.2 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.6 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 3.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 4.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.9 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 1.3 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.8 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 3.4 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.3 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.9 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane