Motif ID: Ezh2_Atf2_Ikzf1

Z-value: 1.715

Transcription factors associated with Ezh2_Atf2_Ikzf1:

Gene SymbolEntrez IDGene Name
Atf2 ENSMUSG00000027104.12 Atf2
Ezh2 ENSMUSG00000029687.10 Ezh2
Ikzf1 ENSMUSG00000018654.11 Ikzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ezh2mm10_v2_chr6_-_47594967_475950470.687.6e-12Click!
Atf2mm10_v2_chr2_-_73892588_738926160.551.9e-07Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Ezh2_Atf2_Ikzf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_34745952 40.883 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
Cald1


caldesmon 1


chr1_-_190170671 37.666 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr6_+_34746368 34.584 ENSMUST00000142716.1
Cald1
caldesmon 1
chr14_-_98169542 28.611 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr3_-_86548268 22.852 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr1_-_190170178 20.941 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr2_+_152081529 20.278 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr9_-_91365756 18.231 ENSMUST00000034927.6
Zic1
zinc finger protein of the cerebellum 1
chr9_-_117252450 17.999 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr9_-_91365778 16.457 ENSMUST00000065360.3
Zic1
zinc finger protein of the cerebellum 1
chr11_+_44617310 15.977 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr15_-_91191733 15.717 ENSMUST00000069511.6
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr4_-_110290884 14.780 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr16_-_59555752 14.746 ENSMUST00000179383.1
ENSMUST00000044604.8
Crybg3

beta-gamma crystallin domain containing 3

chr14_+_28504736 14.542 ENSMUST00000063465.4
Wnt5a
wingless-related MMTV integration site 5A
chr4_-_110287479 13.688 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr6_-_23248264 13.332 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr13_-_78199757 12.026 ENSMUST00000091458.6
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr11_-_84525514 11.774 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr17_-_35704000 11.732 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr5_-_106458440 11.317 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr10_-_120476469 11.049 ENSMUST00000072777.7
ENSMUST00000159699.1
Hmga2

high mobility group AT-hook 2

chr10_-_128176568 9.997 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr13_+_94875600 9.958 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr4_-_82505707 9.853 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr1_+_6730135 9.636 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr7_-_37770757 9.570 ENSMUST00000176680.1
Zfp536
zinc finger protein 536
chr1_+_136467958 9.262 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr17_-_35703971 9.153 ENSMUST00000148065.1
Ddr1
discoidin domain receptor family, member 1
chr11_-_19018956 9.048 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr1_+_6730051 8.740 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chrX_-_88115632 8.478 ENSMUST00000113966.1
ENSMUST00000113964.1
Il1rapl1

interleukin 1 receptor accessory protein-like 1

chr11_+_23020464 8.466 ENSMUST00000094363.3
ENSMUST00000151877.1
Fam161a

family with sequence similarity 161, member A

chr13_-_78197815 8.271 ENSMUST00000127137.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr11_-_84069179 8.199 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr4_+_8691303 8.079 ENSMUST00000051558.3
Chd7
chromodomain helicase DNA binding protein 7
chr13_+_54371340 8.010 ENSMUST00000026985.8
Cplx2
complexin 2
chr1_-_55226768 7.700 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr4_-_53159885 7.452 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr4_-_82505749 7.409 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr1_-_69685937 7.295 ENSMUST00000027146.2
Ikzf2
IKAROS family zinc finger 2
chr10_+_86302854 7.281 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr4_-_91399984 7.100 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr16_+_43503607 7.082 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr9_+_118478182 7.019 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr1_+_66175286 6.975 ENSMUST00000114017.1
ENSMUST00000114015.1
Map2

microtubule-associated protein 2

chr2_-_33942111 6.919 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr9_+_118478344 6.760 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr16_+_43363855 6.729 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr16_-_33056174 6.708 ENSMUST00000115100.1
ENSMUST00000040309.8
Iqcg

IQ motif containing G

chr18_-_72351009 6.551 ENSMUST00000073379.5
Dcc
deleted in colorectal carcinoma
chr18_-_72351029 6.471 ENSMUST00000114943.3
Dcc
deleted in colorectal carcinoma
chr1_-_118982551 6.467 ENSMUST00000159678.1
Gli2
GLI-Kruppel family member GLI2
chr11_-_22001605 6.461 ENSMUST00000006071.7
Otx1
orthodenticle homolog 1 (Drosophila)
chr3_+_156562141 6.446 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr2_-_28916412 6.415 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr11_-_94297067 6.373 ENSMUST00000132623.2
Luc7l3
LUC7-like 3 (S. cerevisiae)
chr3_+_156561950 6.302 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr7_-_37769624 6.253 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr6_-_127151044 6.154 ENSMUST00000000188.8
Ccnd2
cyclin D2
chr2_-_114013619 6.143 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr19_+_55741810 6.127 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr16_+_42907563 6.125 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr9_-_63146980 6.063 ENSMUST00000055281.7
ENSMUST00000119146.1
Skor1

SKI family transcriptional corepressor 1

chr16_+_43247278 6.055 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr4_+_41762309 5.920 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr1_+_66175272 5.895 ENSMUST00000156636.2
Map2
microtubule-associated protein 2
chr14_+_56887795 5.852 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr11_+_84525647 5.844 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr17_-_90455872 5.772 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr2_+_181767040 5.737 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr9_+_64385675 5.668 ENSMUST00000068967.4
Megf11
multiple EGF-like-domains 11
chr11_-_118909487 5.635 ENSMUST00000117731.1
ENSMUST00000106278.2
ENSMUST00000120061.1
ENSMUST00000017576.4
Rbfox3



RNA binding protein, fox-1 homolog (C. elegans) 3



chr8_-_80739497 5.589 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chrX_-_142966709 5.547 ENSMUST00000041317.2
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr11_+_101627942 5.498 ENSMUST00000010506.3
Rdm1
RAD52 motif 1
chr4_+_11704439 5.482 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr2_+_181767283 5.427 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr14_+_13453937 5.345 ENSMUST00000153954.1
Synpr
synaptoporin
chr7_+_31059342 5.264 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr11_-_100354040 5.195 ENSMUST00000173630.1
Hap1
huntingtin-associated protein 1
chr13_-_40733768 5.151 ENSMUST00000110193.2
Tfap2a
transcription factor AP-2, alpha
chr5_-_53707532 5.131 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr5_-_63968867 5.120 ENSMUST00000154169.1
Rell1
RELT-like 1
chr2_-_137116624 5.082 ENSMUST00000028735.7
Jag1
jagged 1
chr7_+_75610038 5.043 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr12_+_52699297 5.022 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr4_-_24430838 5.017 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr4_-_109665249 5.011 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr9_+_65587187 5.006 ENSMUST00000047099.5
ENSMUST00000131483.1
ENSMUST00000141046.1
Pif1


PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)


chr4_-_110292719 4.978 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr16_+_43364145 4.949 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_+_107511489 4.933 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr6_+_149408973 4.896 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chr10_-_23349887 4.845 ENSMUST00000074366.6
ENSMUST00000092665.4
Eya4

eyes absent 4 homolog (Drosophila)

chr6_-_120038647 4.818 ENSMUST00000088646.5
ENSMUST00000177761.1
ENSMUST00000088644.6
ENSMUST00000060043.6
Wnk1



WNK lysine deficient protein kinase 1



chr10_-_62880014 4.803 ENSMUST00000050826.7
Tet1
tet methylcytosine dioxygenase 1
chr6_+_4755327 4.713 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr14_+_54476100 4.711 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr15_-_99820072 4.678 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr1_-_144177259 4.672 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr11_-_87108656 4.632 ENSMUST00000051395.8
Prr11
proline rich 11
chr9_+_65587149 4.611 ENSMUST00000134538.1
ENSMUST00000136205.1
Pif1

PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)

chr14_+_13454010 4.610 ENSMUST00000112656.2
Synpr
synaptoporin
chr12_-_64965496 4.594 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr13_-_23430826 4.591 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr8_-_67818284 4.573 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr17_+_85613432 4.548 ENSMUST00000176081.1
Six3
sine oculis-related homeobox 3
chr10_+_26229707 4.527 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr8_-_67910911 4.471 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr14_+_116925291 4.394 ENSMUST00000078849.4
Gpc6
glypican 6
chr17_+_85620816 4.389 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr3_-_87174657 4.360 ENSMUST00000159976.1
ENSMUST00000107618.2
Kirrel

kin of IRRE like (Drosophila)

chr4_-_110286581 4.353 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr10_+_19356558 4.341 ENSMUST00000053225.5
Olig3
oligodendrocyte transcription factor 3
chr10_-_12861735 4.336 ENSMUST00000076817.4
Utrn
utrophin
chr9_+_64385626 4.327 ENSMUST00000093829.2
ENSMUST00000118485.1
ENSMUST00000164113.1
Megf11


multiple EGF-like-domains 11


chr7_-_116038734 4.300 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chrX_+_136741821 4.279 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr5_+_115845229 4.228 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr7_+_75701965 4.203 ENSMUST00000094307.3
Akap13
A kinase (PRKA) anchor protein 13
chr12_+_98920567 4.134 ENSMUST00000085109.3
ENSMUST00000079146.6
Ttc8

tetratricopeptide repeat domain 8

chr2_+_35132194 4.042 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr10_-_92165159 4.021 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr14_+_116925379 3.988 ENSMUST00000088483.3
Gpc6
glypican 6
chr4_-_92191749 3.987 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr15_+_40655020 3.962 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr19_+_37376359 3.914 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr12_-_46818749 3.899 ENSMUST00000021438.6
Nova1
neuro-oncological ventral antigen 1
chr11_-_69758223 3.801 ENSMUST00000071213.3
Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr1_-_45503282 3.758 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chrX_-_108834303 3.755 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr16_-_26989974 3.741 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr7_-_35802968 3.740 ENSMUST00000061586.4
Zfp507
zinc finger protein 507
chrX_-_113185485 3.736 ENSMUST00000026607.8
ENSMUST00000113388.2
Chm

choroidermia

chr17_-_53463315 3.724 ENSMUST00000024725.4
Efhb
EF hand domain family, member B
chr15_-_84447037 3.690 ENSMUST00000080751.2
1810041L15Rik
RIKEN cDNA 1810041L15 gene
chr5_-_72559599 3.644 ENSMUST00000074948.4
ENSMUST00000087216.5
Nfxl1

nuclear transcription factor, X-box binding-like 1

chr2_+_72297895 3.642 ENSMUST00000144111.1
Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr12_+_64965742 3.641 ENSMUST00000066296.7
Fam179b
family with sequence similarity 179, member B
chr12_+_73286868 3.631 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr14_-_47411666 3.623 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr3_+_102010138 3.609 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr6_+_128362919 3.553 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr7_+_51621830 3.504 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr6_+_83142387 3.491 ENSMUST00000130622.1
ENSMUST00000129316.1
Rtkn

rhotekin

chr2_-_157204483 3.484 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr19_+_38931008 3.483 ENSMUST00000145051.1
Hells
helicase, lymphoid specific
chr8_-_61902669 3.454 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr11_+_29463735 3.449 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr11_-_70656467 3.448 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chrX_+_42149534 3.445 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr2_+_84734050 3.442 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr1_-_136230289 3.439 ENSMUST00000150163.1
ENSMUST00000144464.1
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr17_+_80944611 3.421 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr12_+_73286779 3.419 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr14_+_116925516 3.408 ENSMUST00000125435.1
Gpc6
glypican 6
chr1_-_127677923 3.370 ENSMUST00000160616.1
Tmem163
transmembrane protein 163
chr14_+_120275669 3.349 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr3_+_127633134 3.347 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr11_-_78697370 3.346 ENSMUST00000142739.1
Nlk
nemo like kinase
chr7_-_116031047 3.323 ENSMUST00000106612.1
Sox6
SRY-box containing gene 6
chr9_-_105521147 3.319 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr14_+_54431597 3.317 ENSMUST00000089688.4
Mmp14
matrix metallopeptidase 14 (membrane-inserted)
chr2_-_63184253 3.293 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr14_-_122465677 3.289 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr3_-_87174518 3.276 ENSMUST00000041732.8
Kirrel
kin of IRRE like (Drosophila)
chr14_+_47663756 3.257 ENSMUST00000022391.7
Ktn1
kinectin 1
chr8_+_45658273 3.241 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr2_-_66410064 3.240 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr3_-_94473591 3.233 ENSMUST00000029785.3
Riiad1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr1_-_190169399 3.229 ENSMUST00000010319.7
Prox1
prospero-related homeobox 1
chr4_+_53713998 3.203 ENSMUST00000128667.1
Fktn
fukutin
chr9_+_91368970 3.199 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr2_+_79255500 3.190 ENSMUST00000099972.4
Itga4
integrin alpha 4
chr6_+_11925869 3.164 ENSMUST00000115510.1
ENSMUST00000115511.2
ENSMUST00000090632.4
Phf14


PHD finger protein 14


chr4_-_118437331 3.153 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr6_-_137169678 3.128 ENSMUST00000119610.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr6_-_114921778 3.122 ENSMUST00000032459.7
Vgll4
vestigial like 4 (Drosophila)
chr2_+_4976113 3.110 ENSMUST00000167607.1
ENSMUST00000115010.2
Ucma

upper zone of growth plate and cartilage matrix associated

chr17_-_70851189 3.100 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr1_-_139377094 3.098 ENSMUST00000131586.1
ENSMUST00000145244.1
Crb1

crumbs homolog 1 (Drosophila)

chrX_+_56454871 3.042 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr16_-_55283237 3.014 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr19_+_59458372 3.007 ENSMUST00000062216.3
Emx2
empty spiracles homeobox 2
chr4_-_84674989 3.004 ENSMUST00000175800.1
ENSMUST00000176418.1
ENSMUST00000175969.1
ENSMUST00000176370.1
ENSMUST00000176947.1
ENSMUST00000102820.2
ENSMUST00000107198.2
ENSMUST00000175756.1
ENSMUST00000176691.1
Bnc2








basonuclin 2








chr19_-_58455161 2.994 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr12_-_75177325 2.972 ENSMUST00000042299.2
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr11_-_19018714 2.941 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr14_+_47276910 2.934 ENSMUST00000065562.4
Socs4
suppressor of cytokine signaling 4
chr13_-_36734450 2.921 ENSMUST00000037623.8
Nrn1
neuritin 1
chr2_+_136057927 2.917 ENSMUST00000057503.6
Lamp5
lysosomal-associated membrane protein family, member 5
chr2_+_116067213 2.910 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr7_+_45215753 2.909 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr10_-_92164666 2.904 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr13_+_51846673 2.881 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr17_+_29090969 2.868 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr1_-_134079114 2.863 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr3_+_90220783 2.859 ENSMUST00000065418.6
Rab13
RAB13, member RAS oncogene family
chr8_-_122678653 2.855 ENSMUST00000134045.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
20.6 61.8 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
9.5 28.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
8.8 26.3 GO:0060067 cervix development(GO:0060067)
4.8 19.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
4.6 13.8 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
4.0 12.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
3.6 21.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
3.4 13.6 GO:0021698 cerebellar cortex structural organization(GO:0021698)
3.2 19.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
2.6 5.2 GO:0003404 optic vesicle morphogenesis(GO:0003404)
2.1 18.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
2.0 10.0 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
1.9 1.9 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
1.9 5.6 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
1.9 7.5 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
1.8 11.0 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.8 7.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.8 10.7 GO:0048852 diencephalon morphogenesis(GO:0048852)
1.7 5.1 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.7 21.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.6 19.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.6 3.2 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
1.6 11.0 GO:0060613 fat pad development(GO:0060613)
1.5 6.1 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
1.4 4.3 GO:0007525 somatic muscle development(GO:0007525)
1.4 4.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
1.4 17.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.4 22.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.4 9.6 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
1.3 9.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.3 5.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.3 3.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.2 11.0 GO:0021979 hypothalamus cell differentiation(GO:0021979)
1.2 8.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
1.2 13.1 GO:0060539 diaphragm development(GO:0060539)
1.2 3.5 GO:0021759 globus pallidus development(GO:0021759)
1.1 6.8 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
1.1 8.7 GO:0048625 myoblast fate commitment(GO:0048625)
1.1 4.3 GO:0097476 spinal cord motor neuron migration(GO:0097476)
1.1 25.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
1.0 7.3 GO:0032596 protein transport into membrane raft(GO:0032596)
1.0 5.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.0 1.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
1.0 3.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.0 4.8 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
1.0 3.8 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.9 9.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.9 2.7 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.9 2.7 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.9 3.6 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.9 53.8 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.9 2.6 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.8 1.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.8 3.3 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.8 2.4 GO:0019085 early viral transcription(GO:0019085)
0.8 4.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.8 2.4 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.8 3.2 GO:0050904 diapedesis(GO:0050904)
0.8 11.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.8 2.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.8 31.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.8 3.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.7 9.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.7 2.2 GO:0051653 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001) establishment of spindle localization(GO:0051293) establishment of spindle orientation(GO:0051294) spindle localization(GO:0051653)
0.7 1.4 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.7 2.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.7 2.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.7 4.8 GO:0016584 nucleosome positioning(GO:0016584)
0.7 37.0 GO:0007628 adult walking behavior(GO:0007628)
0.7 4.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.7 2.0 GO:0015793 glycerol transport(GO:0015793)
0.6 1.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.6 13.8 GO:0035855 megakaryocyte development(GO:0035855)
0.6 1.9 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.6 1.8 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.6 1.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 4.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 1.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.6 1.8 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.6 4.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 1.7 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.6 1.7 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.6 3.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.6 7.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.6 2.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.6 2.8 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.5 2.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.5 0.5 GO:0039519 modulation by virus of host autophagy(GO:0039519)
0.5 2.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.5 2.1 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.5 1.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.5 2.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.5 5.1 GO:0043586 tongue development(GO:0043586)
0.5 2.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.5 1.5 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.5 3.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.5 1.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.5 2.5 GO:0035063 nuclear speck organization(GO:0035063)
0.5 3.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 3.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.5 2.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.5 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.5 1.0 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.5 12.6 GO:0010842 retina layer formation(GO:0010842)
0.5 1.9 GO:0006272 leading strand elongation(GO:0006272)
0.5 3.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.5 2.3 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.5 7.0 GO:0046697 decidualization(GO:0046697)
0.5 21.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.5 4.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.5 1.4 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.5 1.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.4 1.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.4 6.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.4 1.3 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.4 3.6 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.4 4.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 1.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.4 1.3 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.4 0.8 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.4 2.1 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.4 2.0 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.4 0.8 GO:1901203 positive regulation of extracellular matrix assembly(GO:1901203)
0.4 0.8 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.4 4.0 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.4 1.6 GO:0003360 brainstem development(GO:0003360)
0.4 3.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.4 1.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 3.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.4 35.4 GO:0043488 regulation of mRNA stability(GO:0043488)
0.4 1.6 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.4 3.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 2.7 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.4 1.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.4 1.9 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.4 3.0 GO:0048664 neuron fate determination(GO:0048664)
0.4 1.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 3.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.4 2.9 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.3 4.2 GO:0003334 keratinocyte development(GO:0003334)
0.3 3.3 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.3 1.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 1.6 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 2.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 6.1 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.3 2.9 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 2.2 GO:0007296 vitellogenesis(GO:0007296)
0.3 1.6 GO:0044793 negative regulation by host of viral process(GO:0044793)
0.3 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 0.9 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.3 1.2 GO:0033603 positive regulation of dopamine secretion(GO:0033603) positive regulation of catecholamine secretion(GO:0033605)
0.3 4.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.3 8.6 GO:0001754 eye photoreceptor cell differentiation(GO:0001754)
0.3 1.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.3 2.0 GO:0051660 establishment of centrosome localization(GO:0051660)
0.3 2.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 3.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.3 2.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 1.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 2.2 GO:0048102 autophagic cell death(GO:0048102)
0.3 1.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 1.1 GO:0044849 estrous cycle(GO:0044849) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3 2.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.3 1.6 GO:0015074 DNA integration(GO:0015074)
0.3 7.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 2.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.3 1.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 1.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 1.0 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.3 1.0 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.3 2.3 GO:0060009 Sertoli cell development(GO:0060009)
0.3 3.5 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.2 3.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 0.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.5 GO:0061370 negative regulation of chronic inflammatory response(GO:0002677) testosterone biosynthetic process(GO:0061370)
0.2 1.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 1.0 GO:0051890 regulation of cardioblast differentiation(GO:0051890) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 1.2 GO:0015867 ATP transport(GO:0015867)
0.2 2.4 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.2 1.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.5 GO:0070827 chromatin maintenance(GO:0070827)
0.2 0.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.2 2.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 0.7 GO:0021553 olfactory nerve development(GO:0021553)
0.2 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2 1.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.1 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.2 16.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 1.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 1.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 5.0 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 1.1 GO:0048733 sebaceous gland development(GO:0048733)
0.2 2.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 1.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 3.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 0.6 GO:0097274 urea homeostasis(GO:0097274)
0.2 0.6 GO:1990839 response to endothelin(GO:1990839)
0.2 4.7 GO:0043486 histone exchange(GO:0043486)
0.2 2.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.2 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 3.6 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.2 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.2 0.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 19.3 GO:0045727 positive regulation of translation(GO:0045727)
0.2 1.4 GO:0006691 leukotriene metabolic process(GO:0006691)
0.2 0.2 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
0.2 1.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 0.6 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.2 7.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.2 1.9 GO:0009404 toxin metabolic process(GO:0009404)
0.2 0.9 GO:0061009 common bile duct development(GO:0061009)
0.2 0.9 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 0.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 0.2 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.2 0.9 GO:0015671 oxygen transport(GO:0015671)
0.2 0.5 GO:0016598 protein arginylation(GO:0016598)
0.2 0.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 2.8 GO:0030308 negative regulation of cell growth(GO:0030308)
0.2 0.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.7 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 1.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 2.6 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.2 6.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 3.5 GO:0043029 T cell homeostasis(GO:0043029)
0.2 1.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.2 1.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.2 0.7 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.2 2.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 2.9 GO:0048368 lateral mesoderm development(GO:0048368)
0.2 0.6 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 1.4 GO:0030259 lipid glycosylation(GO:0030259)
0.2 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.2 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 1.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.0 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.1 0.6 GO:0006547 histidine metabolic process(GO:0006547)
0.1 1.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 0.1 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.9 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.6 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 6.1 GO:0030901 midbrain development(GO:0030901)
0.1 0.7 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 1.2 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.1 0.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 2.6 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 2.0 GO:0045911 positive regulation of isotype switching(GO:0045830) positive regulation of DNA recombination(GO:0045911)
0.1 0.4 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.7 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.2 GO:1904738 vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752) positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.1 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.7 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 1.4 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 3.6 GO:0007588 excretion(GO:0007588)
0.1 2.6 GO:0016180 snRNA processing(GO:0016180)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.2 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.3 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 0.3 GO:0030473 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815) nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.1 0.3 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.1 0.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.7 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.1 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 2.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.6 GO:0046684 response to pyrethroid(GO:0046684)
0.1 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.9 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 5.4 GO:0050684 regulation of mRNA processing(GO:0050684)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 0.2 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 2.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 2.1 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.3 GO:0050926 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927)
0.1 2.0 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 3.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.8 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.5 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.4 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 1.0 GO:0060117 auditory receptor cell development(GO:0060117)
0.1 0.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 1.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 4.5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 0.9 GO:0051450 myoblast proliferation(GO:0051450)
0.1 8.5 GO:0044782 cilium organization(GO:0044782)
0.1 1.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.5 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 0.8 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 1.0 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 1.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 2.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.3 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1 0.4 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.6 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.8 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 1.6 GO:0045931 positive regulation of mitotic cell cycle(GO:0045931)
0.1 0.2 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.0 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.1 GO:0031297 replication fork processing(GO:0031297)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 1.1 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.3 GO:1903055 positive regulation of extracellular matrix organization(GO:1903055)
0.1 0.9 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 1.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.0 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 2.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 2.8 GO:0051310 metaphase plate congression(GO:0051310)
0.1 1.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672) xenobiotic transport(GO:0042908)
0.1 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 1.2 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.7 GO:0060349 bone morphogenesis(GO:0060349)
0.1 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.4 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.1 GO:0072553 terminal button organization(GO:0072553)
0.1 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.5 GO:0015838 amino-acid betaine transport(GO:0015838)
0.1 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 2.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.7 GO:0032526 response to retinoic acid(GO:0032526)
0.1 1.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.1 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.8 GO:0035315 hair cell differentiation(GO:0035315) auditory receptor cell differentiation(GO:0042491)
0.0 1.9 GO:0007338 single fertilization(GO:0007338)
0.0 1.5 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.5 GO:0070168 negative regulation of biomineral tissue development(GO:0070168)
0.0 0.3 GO:0035265 organ growth(GO:0035265)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.7 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.7 GO:0030033 microvillus assembly(GO:0030033)
0.0 1.0 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 1.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.9 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 1.0 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0021855 hypothalamus cell migration(GO:0021855)
0.0 0.9 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0009409 response to cold(GO:0009409)
0.0 0.0 GO:2000426 interleukin-4-mediated signaling pathway(GO:0035771) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 2.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0010506 regulation of autophagy(GO:0010506)
0.0 4.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0072176 nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890)
0.0 0.7 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.3 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:1901341 positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 1.9 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.0 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.1 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.7 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.7 GO:0035904 aorta development(GO:0035904)
0.0 0.2 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.7 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.4 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.0 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.9 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0006826 iron ion transport(GO:0006826)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 80.2 GO:0030478 actin cap(GO:0030478)
2.6 38.5 GO:0042788 polysomal ribosome(GO:0042788)
2.0 8.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.7 15.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.6 3.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.5 6.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.5 16.1 GO:0032584 growth cone membrane(GO:0032584)
1.3 4.0 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.3 3.8 GO:0005588 collagen type V trimer(GO:0005588)
1.0 4.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.0 11.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.0 2.9 GO:0070557 PCNA-p21 complex(GO:0070557)
1.0 2.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.0 3.8 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.9 2.8 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.8 6.9 GO:0002177 manchette(GO:0002177)
0.8 3.0 GO:0060187 cell pole(GO:0060187)
0.8 16.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.7 3.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.6 5.1 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.6 1.9 GO:0005899 insulin receptor complex(GO:0005899)
0.5 1.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.5 6.5 GO:0097542 ciliary tip(GO:0097542)
0.5 5.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.5 3.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.5 1.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 14.7 GO:0051233 spindle midzone(GO:0051233)
0.4 6.1 GO:0000974 Prp19 complex(GO:0000974)
0.4 2.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.4 7.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 2.4 GO:0043256 laminin complex(GO:0043256)
0.4 2.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 1.6 GO:0045098 type III intermediate filament(GO:0045098)
0.4 4.1 GO:0034464 BBSome(GO:0034464)
0.4 1.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 8.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 5.1 GO:0005922 connexon complex(GO:0005922)
0.3 18.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 6.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.3 4.3 GO:0070938 contractile ring(GO:0070938)
0.3 1.9 GO:0098536 deuterosome(GO:0098536)
0.3 1.5 GO:1990246 uniplex complex(GO:1990246)
0.3 2.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 2.0 GO:0033503 HULC complex(GO:0033503)
0.3 3.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 1.1 GO:0044307 dendritic branch(GO:0044307)
0.3 1.1 GO:0031673 H zone(GO:0031673)
0.3 2.1 GO:0072687 meiotic spindle(GO:0072687)
0.3 6.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 3.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 4.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 3.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 1.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 2.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 8.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 21.6 GO:0005814 centriole(GO:0005814)
0.2 0.6 GO:1990047 spindle matrix(GO:1990047)
0.2 1.0 GO:0070876 SOSS complex(GO:0070876)
0.2 0.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 1.8 GO:0036157 outer dynein arm(GO:0036157)
0.2 1.5 GO:0097165 nuclear stress granule(GO:0097165)
0.2 2.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.0 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 1.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 0.5 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 1.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 2.6 GO:0032039 integrator complex(GO:0032039)
0.2 11.6 GO:0005657 replication fork(GO:0005657)
0.2 3.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 13.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 1.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 11.5 GO:0036064 ciliary basal body(GO:0036064)
0.2 3.2 GO:0097228 sperm principal piece(GO:0097228)
0.2 1.7 GO:0016342 catenin complex(GO:0016342)
0.2 3.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 20.9 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.4 GO:0000235 astral microtubule(GO:0000235)
0.1 1.2 GO:0061574 ASAP complex(GO:0061574)
0.1 1.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.5 GO:0000242 pericentriolar material(GO:0000242)
0.1 3.9 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 5.0 GO:0005902 microvillus(GO:0005902)
0.1 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.1 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.4 GO:0030891 VCB complex(GO:0030891)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 1.2 GO:0002080 acrosomal membrane(GO:0002080)
0.1 7.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 2.7 GO:0005815 microtubule organizing center(GO:0005815)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.5 GO:0002102 podosome(GO:0002102)
0.1 1.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.1 11.5 GO:0005813 centrosome(GO:0005813)
0.1 0.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.9 GO:0016235 aggresome(GO:0016235)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 8.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 0.6 GO:0005883 neurofilament(GO:0005883)
0.1 1.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 2.0 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 3.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.5 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0097227 sperm annulus(GO:0097227)
0.1 2.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 2.0 GO:0005811 lipid particle(GO:0005811)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 1.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 7.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0000346 transcription export complex(GO:0000346)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 270.7 GO:0005634 nucleus(GO:0005634)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 2.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.7 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 2.8 GO:0015630 microtubule cytoskeleton(GO:0015630)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 61.8 GO:0050693 LBD domain binding(GO:0050693)
4.8 14.5 GO:0005110 frizzled-2 binding(GO:0005110)
3.8 30.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
3.4 37.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
3.2 9.6 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
2.5 7.6 GO:0004531 deoxyribonuclease II activity(GO:0004531)
2.5 7.5 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
2.4 21.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
2.2 13.0 GO:0005042 netrin receptor activity(GO:0005042)
1.8 14.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.7 6.8 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
1.6 4.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
1.5 18.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.5 5.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
1.1 11.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
1.1 40.5 GO:0017091 AU-rich element binding(GO:0017091)
1.0 6.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.0 4.0 GO:0050436 microfibril binding(GO:0050436)
1.0 35.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.0 2.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.9 7.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.8 3.3 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.8 6.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.7 2.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.7 8.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.7 3.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.6 11.0 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.6 3.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.6 6.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.6 1.8 GO:0030350 iron-responsive element binding(GO:0030350)
0.6 1.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 10.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.6 13.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.6 3.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.5 17.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.5 3.8 GO:0070087 DNA translocase activity(GO:0015616) chromo shadow domain binding(GO:0070087)
0.5 3.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.5 2.6 GO:0005113 patched binding(GO:0005113)
0.5 2.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.5 1.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.5 2.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 1.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.5 3.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.5 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 2.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.5 1.9 GO:0008142 oxysterol binding(GO:0008142)
0.5 1.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.5 9.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.5 8.6 GO:0070410 co-SMAD binding(GO:0070410)
0.4 6.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 1.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.4 5.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 3.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 2.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 1.6 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 1.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.4 1.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.4 66.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 1.6 GO:0046790 virion binding(GO:0046790)
0.4 1.6 GO:1990254 keratin filament binding(GO:1990254)
0.4 1.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 1.9 GO:0043515 kinetochore binding(GO:0043515)
0.4 7.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 2.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 1.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.4 1.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.4 1.8 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.4 2.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 1.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 2.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.4 18.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 5.0 GO:0043495 protein anchor(GO:0043495)
0.4 1.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4 2.1 GO:0043559 insulin binding(GO:0043559)
0.4 1.4 GO:0015254 glycerol channel activity(GO:0015254)
0.3 0.7 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.3 3.5 GO:0004386 helicase activity(GO:0004386)
0.3 2.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.3 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.3 0.7 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.3 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.3 21.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.3 5.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 2.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 4.0 GO:0070888 E-box binding(GO:0070888)
0.3 1.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 4.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 2.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 1.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.3 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 0.8 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.3 7.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 1.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 2.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.3 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 1.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 72.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 1.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 0.8 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.3 1.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.3 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 5.0 GO:0043422 protein kinase B binding(GO:0043422)
0.2 14.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 1.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 1.2 GO:0045545 syndecan binding(GO:0045545)
0.2 1.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 1.8 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.2 0.9 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.7 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.2 1.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 0.9 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 1.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 3.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 0.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.0 GO:0043532 angiostatin binding(GO:0043532)
0.2 2.0 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 6.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 18.7 GO:0001047 core promoter binding(GO:0001047)
0.2 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 0.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 2.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 2.2 GO:0016805 dipeptidase activity(GO:0016805)
0.2 2.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 0.7 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.2 2.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 2.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.2 5.7 GO:0005112 Notch binding(GO:0005112)
0.2 2.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 3.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 2.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 3.2 GO:0031402 sodium ion binding(GO:0031402)
0.2 1.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 0.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 1.4 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.5 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 2.0 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 2.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 6.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 2.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 5.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.1 2.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.1 GO:0030553 cGMP binding(GO:0030553)
0.1 6.2 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 1.9 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 3.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 5.6 GO:0042393 histone binding(GO:0042393)
0.1 0.4 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 6.0 GO:0017022 myosin binding(GO:0017022)
0.1 0.5 GO:0050733 RS domain binding(GO:0050733)
0.1 3.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.0 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 1.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 4.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.7 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 4.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 43.0 GO:0003779 actin binding(GO:0003779)
0.1 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 4.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 2.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 14.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 3.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 6.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.8 GO:0003682 chromatin binding(GO:0003682)
0.1 0.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 7.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.3 GO:0019003 GDP binding(GO:0019003)
0.1 1.5 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 4.0 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996) fatty-acyl-CoA synthase activity(GO:0004321)
0.1 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 2.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.4 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 7.5 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 2.1 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.8 GO:0020037 heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.0 2.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.2 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.2 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.2 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0097001 ceramide binding(GO:0097001)
0.0 0.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.6 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5 15.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.4 20.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.4 11.2 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.4 1.1 PID_IGF1_PATHWAY IGF1 pathway
0.3 2.8 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 2.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 8.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.3 14.9 PID_IL12_2PATHWAY IL12-mediated signaling events
0.2 8.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 8.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.2 3.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 8.0 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.2 10.6 PID_LKB1_PATHWAY LKB1 signaling events
0.2 9.9 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.2 2.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.2 9.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 20.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 6.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 1.4 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.2 4.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 10.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.2 8.7 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 8.4 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 2.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.8 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.7 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 4.8 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.0 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.1 2.9 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.0 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 2.0 ST_ADRENERGIC Adrenergic Pathway
0.1 2.0 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 1.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 2.2 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 1.7 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 2.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.3 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 4.0 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 1.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.5 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.5 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 5.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 1.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 1.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 0.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 6.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.6 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.3 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.3 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 1.5 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.4 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.2 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 77.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
1.3 14.2 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.6 16.6 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.6 12.0 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 3.0 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 7.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.5 5.7 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.5 1.8 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.5 19.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.4 9.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.4 4.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.3 6.3 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3 11.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 4.0 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 12.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.3 19.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 2.7 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.3 4.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 0.8 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 2.8 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.2 2.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.2 1.0 REACTOME_INFLUENZA_LIFE_CYCLE Genes involved in Influenza Life Cycle
0.2 2.8 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.2 5.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 2.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.2 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.2 4.2 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 10.0 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 1.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 4.7 REACTOME_KINESINS Genes involved in Kinesins
0.2 6.4 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.2 4.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 3.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.9 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.0 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.1 0.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.8 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.1 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.0 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.7 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.6 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.0 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 6.2 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.5 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 8.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 8.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 4.0 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.1 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 2.5 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.9 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.5 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 0.6 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.1 0.5 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.4 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.1 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 2.1 REACTOME_MEIOSIS Genes involved in Meiosis
0.1 1.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.0 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 0.2 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME_PI3K_AKT_ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 1.9 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin