Motif ID: Foxf2
Z-value: 1.452
Transcription factors associated with Foxf2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxf2 | ENSMUSG00000038402.2 | Foxf2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxf2 | mm10_v2_chr13_+_31625802_31625816 | 0.21 | 7.0e-02 | Click! |
Top targets:
Showing 1 to 20 of 111 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 65 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.7 | 51.2 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 9.6 | 47.9 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.0 | 39.7 | GO:0006396 | RNA processing(GO:0006396) |
| 0.3 | 24.5 | GO:0048663 | neuron fate commitment(GO:0048663) |
| 2.1 | 19.1 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 1.0 | 18.4 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 1.4 | 18.2 | GO:0070842 | aggresome assembly(GO:0070842) |
| 2.8 | 17.0 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 0.2 | 16.9 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 1.8 | 16.6 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 1.4 | 13.5 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.8 | 11.6 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.2 | 9.9 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 1.2 | 9.7 | GO:0033625 | positive regulation of integrin activation(GO:0033625) |
| 1.9 | 9.4 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
| 0.4 | 9.3 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) |
| 2.5 | 7.5 | GO:0009826 | unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.1 | 6.3 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.8 | 6.2 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.2 | 5.6 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 34 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 59.7 | GO:0005739 | mitochondrion(GO:0005739) |
| 1.4 | 51.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 38.9 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.1 | 38.6 | GO:0014069 | postsynaptic density(GO:0014069) |
| 0.1 | 20.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 20.4 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 16.6 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 11.7 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.2 | 10.2 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.2 | 9.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.6 | 9.7 | GO:1990635 | proximal dendrite(GO:1990635) |
| 3.1 | 9.4 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.6 | 7.5 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 6.2 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 4.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.4 | 4.6 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.2 | 4.2 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.4 | 3.7 | GO:0071664 | catenin-TCF7L2 complex(GO:0071664) |
| 0.3 | 3.7 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 3.6 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 49 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 56.1 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 1.2 | 51.2 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 36.9 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.3 | 19.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 17.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 1.4 | 15.8 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 15.2 | GO:0019904 | protein domain specific binding(GO:0019904) |
| 0.2 | 13.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 11.0 | GO:0008289 | lipid binding(GO:0008289) |
| 1.7 | 9.9 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 9.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 2.4 | 9.4 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.0 | 8.3 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.4 | 8.0 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 6.2 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 5.9 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 5.2 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.4 | 5.1 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.2 | 4.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 1.6 | 4.8 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 22 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 51.2 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 1.4 | 43.2 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.6 | 19.1 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.5 | 14.0 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.4 | 13.5 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.2 | 11.6 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.6 | 9.9 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.1 | 8.1 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 7.6 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.2 | 6.6 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.2 | 4.9 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.2 | 4.4 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.2 | 4.2 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.2 | 3.7 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 2.6 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 2.3 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 1.8 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.1 | 1.5 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.4 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 1.2 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 24 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 18.4 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.5 | 16.9 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.6 | 15.8 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.3 | 11.2 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.3 | 9.9 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
| 0.1 | 9.5 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 9.4 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 8.1 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 6.1 | REACTOME_SIGNALLING_BY_NGF | Genes involved in Signalling by NGF |
| 0.0 | 5.6 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.3 | 4.7 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 4.7 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.3 | 4.4 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.1 | 4.2 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 3.5 | REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION | Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription |
| 0.1 | 3.1 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.2 | 2.9 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.2 | 2.7 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 2.7 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 2.6 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
