Motif ID: Foxg1

Z-value: 0.398


Transcription factors associated with Foxg1:

Gene SymbolEntrez IDGene Name
Foxg1 ENSMUSG00000020950.9 Foxg1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxg1mm10_v2_chr12_+_49382791_49382883-0.503.6e-06Click!


Activity profile for motif Foxg1.

activity profile for motif Foxg1


Sorted Z-values histogram for motif Foxg1

Sorted Z-values for motif Foxg1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxg1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_120476469 6.400 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr2_-_57124003 4.156 ENSMUST00000112629.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr18_-_34007206 4.106 ENSMUST00000025234.5
 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr15_-_85581809 3.017 ENSMUST00000023015.7
 Wnt7b
wingless-related MMTV integration site 7B
chr11_-_28583995 2.771 ENSMUST00000146385.2
 Ccdc85a
coiled-coil domain containing 85A
chr1_-_84284423 2.349 ENSMUST00000176720.1
 Pid1
phosphotyrosine interaction domain containing 1
chr9_+_91378636 1.548 ENSMUST00000066384.5
 Zic4
zinc finger protein of the cerebellum 4
chr12_-_10900296 1.540 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr3_-_127225847 1.529 ENSMUST00000182726.1
ENSMUST00000182779.1
 Ank2

ankyrin 2, brain

chr13_-_3918157 1.524 ENSMUST00000091853.4
 Net1
neuroepithelial cell transforming gene 1
chr15_-_95528228 1.518 ENSMUST00000075275.2
 Nell2
NEL-like 2
chr15_-_95528702 1.486 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr3_-_127225917 1.459 ENSMUST00000182064.1
ENSMUST00000182662.1
 Ank2

ankyrin 2, brain

chr18_+_11839220 1.340 ENSMUST00000171109.1
ENSMUST00000046948.8
 Cables1

CDK5 and Abl enzyme substrate 1

chr9_-_60649793 1.209 ENSMUST00000053171.7
 Lrrc49
leucine rich repeat containing 49
chr16_-_28929658 1.161 ENSMUST00000100023.1
 Mb21d2
Mab-21 domain containing 2
chr2_-_154558834 1.000 ENSMUST00000109716.2
ENSMUST00000000895.6
ENSMUST00000125793.1
 Necab3


N-terminal EF-hand calcium binding protein 3


chr14_-_121698417 0.917 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr19_-_4943049 0.895 ENSMUST00000133254.1
ENSMUST00000120475.1
ENSMUST00000025834.7
 Peli3


pellino 3


chr5_-_142906702 0.889 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
 Actb


actin, beta


chr2_-_152830615 0.850 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
 Bcl2l1



BCL2-like 1



chr10_+_22158566 0.817 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr12_-_104751900 0.777 ENSMUST00000041987.6
 Dicer1
dicer 1, ribonuclease type III
chr12_-_59011996 0.758 ENSMUST00000021375.5
 Sec23a
SEC23A (S. cerevisiae)
chr13_-_71963713 0.709 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr3_-_50443603 0.657 ENSMUST00000029297.4
 Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr11_+_72607221 0.592 ENSMUST00000021148.6
ENSMUST00000138247.1
 Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr2_-_152831112 0.565 ENSMUST00000128172.1
 Bcl2l1
BCL2-like 1
chr4_+_141793612 0.514 ENSMUST00000097805.4
ENSMUST00000030747.4
ENSMUST00000153094.1
 Casp9


caspase 9


chr4_-_108833544 0.503 ENSMUST00000102740.1
ENSMUST00000102741.1
 Btf3l4

basic transcription factor 3-like 4

chr2_+_174330006 0.399 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
 Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr13_+_34162953 0.365 ENSMUST00000124996.1
ENSMUST00000147632.1
 Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chr11_-_97744659 0.337 ENSMUST00000018691.8
 Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr9_+_54586450 0.334 ENSMUST00000167866.1
 Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr6_-_12109583 0.312 ENSMUST00000080891.5
 Gm6578
predicted gene 6578
chr14_-_24245913 0.303 ENSMUST00000073687.6
ENSMUST00000090398.4
 Dlg5

discs, large homolog 5 (Drosophila)

chr6_-_72345144 0.250 ENSMUST00000070345.3
 Usp39
ubiquitin specific peptidase 39
chr16_-_90284300 0.210 ENSMUST00000163419.1
 Scaf4
SR-related CTD-associated factor 4
chr2_-_164389095 0.185 ENSMUST00000167427.1
 Slpi
secretory leukocyte peptidase inhibitor
chr8_-_33641940 0.174 ENSMUST00000095349.4
 Ubxn8
UBX domain protein 8
chr9_+_72925622 0.171 ENSMUST00000038489.5
 Pygo1
pygopus 1
chr9_+_106170918 0.168 ENSMUST00000020490.5
 Wdr82
WD repeat domain containing 82
chr9_+_64121501 0.167 ENSMUST00000118215.1
 Lctl
lactase-like
chr18_-_68300194 0.148 ENSMUST00000152193.1
 Fam210a
family with sequence similarity 210, member A
chr19_+_11770415 0.116 ENSMUST00000167199.1
 Mrpl16
mitochondrial ribosomal protein L16
chr11_+_3488275 0.116 ENSMUST00000064265.6
 Pla2g3
phospholipase A2, group III
chr16_-_90284412 0.112 ENSMUST00000039280.7
 Scaf4
SR-related CTD-associated factor 4
chr5_-_106696530 0.055 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
 Zfp644




zinc finger protein 644




chr1_+_82839449 0.051 ENSMUST00000113444.1
ENSMUST00000063380.4
 Agfg1

ArfGAP with FG repeats 1

chr5_-_134314678 0.047 ENSMUST00000174354.1
ENSMUST00000174155.1
ENSMUST00000174513.1
ENSMUST00000174772.1
ENSMUST00000173341.1
ENSMUST00000111261.4
ENSMUST00000082057.3
ENSMUST00000059042.7
 Gtf2i







general transcription factor II I







chr7_-_115824699 0.046 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr11_-_89538556 0.017 ENSMUST00000169201.1
 Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr5_+_34369909 0.017 ENSMUST00000180376.1
 Fam193a
family with sequence similarity 193, member A
chr12_+_112999964 0.007 ENSMUST00000180971.1
 9230104M06Rik
RIKEN cDNA 9230104M06 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:0051866 general adaptation syndrome(GO:0051866)
1.0 3.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.7 6.4 GO:0060613 fat pad development(GO:0060613)
0.6 2.3 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.4 1.4 GO:0046898 response to cycloheximide(GO:0046898)
0.3 3.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 0.9 GO:0070428 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.3 0.9 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 3.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 0.8 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.2 0.7 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 1.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 1.5 GO:0051451 myoblast migration(GO:0051451)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.8 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.5 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0019731 antibacterial humoral response(GO:0019731)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.5 GO:0043293 apoptosome(GO:0043293)
0.1 3.0 GO:0031430 M band(GO:0031430)
0.1 1.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.8 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 3.0 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 4.2 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.4 6.4 GO:0003680 AT DNA binding(GO:0003680)
0.3 0.9 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2 0.7 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 1.4 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.8 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 4.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 3.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 3.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.9 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 2.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 WNT_SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.9 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 4.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.9 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.7 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG