Motif ID: Foxi1_Foxo1

Z-value: 2.992

Transcription factors associated with Foxi1_Foxo1:

Gene SymbolEntrez IDGene Name
Foxi1 ENSMUSG00000047861.2 Foxi1
Foxo1 ENSMUSG00000044167.5 Foxo1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo1mm10_v2_chr3_+_52268337_522683880.037.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Foxi1_Foxo1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 121.656 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr3_-_52104891 75.790 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr8_+_34807287 67.639 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr2_+_181767283 64.707 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr2_+_181767040 64.542 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr17_-_70851710 47.706 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr7_-_37773555 47.172 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr15_+_25752860 45.742 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chr14_+_73237891 44.065 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr10_-_92165159 43.660 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr3_-_27153861 41.477 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr7_-_115824699 40.941 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr1_+_6487231 40.164 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr3_-_27153844 39.689 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2

ect2 oncogene

chr11_-_101551837 37.177 ENSMUST00000017290.4
Brca1
breast cancer 1
chr18_+_5593566 36.479 ENSMUST00000160910.1
Zeb1
zinc finger E-box binding homeobox 1
chr4_-_97584605 36.052 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584612 35.911 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_-_69206146 35.319 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr15_-_84855093 35.167 ENSMUST00000016768.5
Phf21b
PHD finger protein 21B
chr17_+_29090969 34.798 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr3_-_27153782 34.506 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene


chr1_-_138619687 32.650 ENSMUST00000027642.2
Nek7
NIMA (never in mitosis gene a)-related expressed kinase 7
chr18_-_47333311 32.302 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr1_-_139377094 32.127 ENSMUST00000131586.1
ENSMUST00000145244.1
Crb1

crumbs homolog 1 (Drosophila)

chr8_-_122699066 31.647 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr2_+_128126030 29.234 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr4_-_117178726 29.165 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr2_-_60125651 28.413 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr4_-_133967235 28.405 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_+_34314757 28.255 ENSMUST00000165963.1
ENSMUST00000093192.3
Fam196b

family with sequence similarity 196, member B

chr8_-_53638945 28.223 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr2_+_38511643 28.174 ENSMUST00000054234.3
ENSMUST00000112902.1
ENSMUST00000112895.1
Nek6


NIMA (never in mitosis gene a)-related expressed kinase 6


chr7_-_37772868 28.125 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr1_+_136467958 28.072 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr6_+_34598530 27.946 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr6_-_56369625 27.451 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
Pde1c


phosphodiesterase 1C


chr13_-_103920295 27.178 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr1_-_139377041 26.983 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr2_+_145785980 26.205 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chr6_+_34598500 26.157 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr12_+_109452833 26.111 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr10_+_37139558 25.930 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr6_+_14901344 25.517 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr4_-_109665249 25.162 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr2_-_51149100 25.096 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr16_-_50432340 24.376 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr3_+_34649987 23.996 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr4_-_43499608 23.474 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr7_+_51621830 23.382 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr9_+_65890237 23.248 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr19_+_37376359 23.049 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr10_-_92162753 22.934 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chrX_+_35888808 22.767 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr12_-_31950170 22.683 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chrX_+_9885622 22.499 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr19_+_53329413 22.431 ENSMUST00000025998.7
Mxi1
Max interacting protein 1
chr1_-_138848576 22.403 ENSMUST00000112030.2
Lhx9
LIM homeobox protein 9
chr19_+_55741810 22.302 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr6_-_39557830 22.071 ENSMUST00000036877.3
ENSMUST00000154149.1
Dennd2a

DENN/MADD domain containing 2A

chr2_-_127133909 21.390 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr14_+_55853997 21.316 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr11_+_69045640 21.280 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr12_-_31950210 21.076 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr12_-_31950535 21.066 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr14_-_31640878 21.030 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chrX_+_101254528 20.709 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr14_-_62456286 20.492 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr4_-_59549243 20.478 ENSMUST00000173699.1
ENSMUST00000173884.1
ENSMUST00000102883.4
ENSMUST00000174586.1
Ptbp3



polypyrimidine tract binding protein 3



chr9_+_119402444 20.397 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr5_-_99252839 20.339 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr2_+_26973416 20.320 ENSMUST00000014996.7
ENSMUST00000102891.3
Adamts13

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

chr2_-_18048784 19.624 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr4_+_105157339 19.506 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr4_+_65124174 19.468 ENSMUST00000084501.3
Pappa
pregnancy-associated plasma protein A
chrX_-_141725181 19.460 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr16_-_22161450 19.180 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr8_+_45507768 19.063 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr4_-_117182623 18.954 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr13_+_51846673 18.670 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr6_+_53573364 18.614 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr2_-_168601620 18.564 ENSMUST00000171689.1
ENSMUST00000137451.1
Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

chr12_+_38781093 17.693 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr11_-_102925086 17.685 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr7_+_75455534 17.454 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr5_+_64812336 17.311 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr1_-_14310198 17.309 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr5_+_139543889 17.202 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr5_+_137745730 17.135 ENSMUST00000100540.3
Tsc22d4
TSC22 domain family, member 4
chr2_-_64097994 17.066 ENSMUST00000131615.2
Fign
fidgetin
chr8_+_127064022 16.941 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr1_-_171281181 16.865 ENSMUST00000073120.4
Ppox
protoporphyrinogen oxidase
chr8_+_45658666 16.592 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr2_+_119047116 16.563 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr5_+_137745967 16.553 ENSMUST00000100539.3
Tsc22d4
TSC22 domain family, member 4
chr8_+_45627946 16.518 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr11_-_88718223 16.437 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr17_+_78491549 16.427 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr8_+_116504973 16.390 ENSMUST00000078170.5
Dynlrb2
dynein light chain roadblock-type 2
chr10_-_128180265 16.372 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr11_-_88718078 16.369 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr8_+_45658731 16.119 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr17_+_29093763 16.048 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr7_-_116038734 15.990 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr10_-_92164666 15.976 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chrX_+_112311334 15.976 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr6_+_34709610 15.924 ENSMUST00000031775.6
Cald1
caldesmon 1
chr11_-_12027958 15.859 ENSMUST00000109654.1
Grb10
growth factor receptor bound protein 10
chr12_+_71136848 15.794 ENSMUST00000149564.1
ENSMUST00000045907.8
2700049A03Rik

RIKEN cDNA 2700049A03 gene

chr8_+_45628176 15.761 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr2_+_118598209 15.739 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr6_+_48860339 15.485 ENSMUST00000101425.3
Gm7932
predicted gene 7932
chr10_+_96616998 15.474 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr4_+_89688196 15.450 ENSMUST00000052478.2
Dmrta1
doublesex and mab-3 related transcription factor like family A1
chr6_-_39206782 15.338 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr16_-_36784924 15.301 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr1_-_118982551 15.263 ENSMUST00000159678.1
Gli2
GLI-Kruppel family member GLI2
chr18_-_13972617 15.093 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr14_+_54259227 15.055 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr16_-_50330987 14.981 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr8_+_45627709 14.879 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr6_+_15185456 14.867 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr4_-_133967893 14.863 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr6_+_83135812 14.857 ENSMUST00000065512.4
Rtkn
rhotekin
chr9_+_96196246 14.846 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr7_-_38107490 14.765 ENSMUST00000108023.3
Ccne1
cyclin E1
chr12_+_52516077 14.696 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr16_-_36784784 14.608 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr3_-_63851251 14.602 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr19_-_34879452 14.548 ENSMUST00000036584.5
Pank1
pantothenate kinase 1
chr4_+_11191726 14.384 ENSMUST00000029866.9
ENSMUST00000108324.3
Ccne2

cyclin E2

chrX_+_151521146 14.315 ENSMUST00000112670.1
ENSMUST00000046962.4
ENSMUST00000112668.2
ENSMUST00000046950.6
Phf8



PHD finger protein 8



chr11_-_86993682 14.282 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr2_-_62483637 14.209 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr10_-_93311073 14.111 ENSMUST00000008542.5
Elk3
ELK3, member of ETS oncogene family
chr4_-_110290884 14.023 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr10_-_49783259 13.980 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr4_-_138725262 13.923 ENSMUST00000105811.2
Ubxn10
UBX domain protein 10
chr17_-_34627148 13.912 ENSMUST00000171376.1
ENSMUST00000169287.1
Ppt2

palmitoyl-protein thioesterase 2

chr4_-_110292719 13.855 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_+_5218546 13.850 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr2_+_119047129 13.742 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr7_+_80186835 13.702 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr12_+_38780817 13.648 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr17_+_40115358 13.551 ENSMUST00000061746.7
Gm7148
predicted gene 7148
chr14_+_46832127 13.376 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr7_+_79660196 13.323 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr11_+_119022962 13.300 ENSMUST00000026662.7
Cbx2
chromobox 2
chr2_+_84839395 13.263 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr6_+_8948608 13.245 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chrX_+_106920618 13.115 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr3_+_146500071 13.098 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr9_-_42461414 13.097 ENSMUST00000066179.7
Tbcel
tubulin folding cofactor E-like
chr6_+_34709442 13.029 ENSMUST00000115021.1
Cald1
caldesmon 1
chr4_+_97772734 13.004 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chr4_+_11704439 12.983 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr3_-_36571952 12.941 ENSMUST00000029270.3
Ccna2
cyclin A2
chr4_-_21767173 12.940 ENSMUST00000029915.5
Tstd3
thiosulfate sulfurtransferase (rhodanese)-like domain containing 3
chr15_+_72913357 12.912 ENSMUST00000166418.2
Gm3150
predicted gene 3150
chr1_+_74391479 12.909 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr4_-_133967953 12.892 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr14_+_55854115 12.833 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr12_+_71016658 12.766 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr4_+_52439235 12.681 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
Smc2


structural maintenance of chromosomes 2


chr8_+_116921735 12.619 ENSMUST00000034205.4
Cenpn
centromere protein N
chr10_+_88091070 12.581 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr17_-_34627365 12.575 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
Ppt2




palmitoyl-protein thioesterase 2




chr15_-_99651580 12.486 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
Racgap1




Rac GTPase-activating protein 1




chrX_-_143827391 12.462 ENSMUST00000087316.5
Capn6
calpain 6
chr18_+_50030977 12.412 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr13_+_4191163 12.374 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr1_-_97977233 12.343 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr17_-_35697971 12.287 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr18_+_4920509 12.231 ENSMUST00000126977.1
Svil
supervillin
chr19_+_59458372 12.227 ENSMUST00000062216.3
Emx2
empty spiracles homeobox 2
chr5_-_149051604 12.199 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr6_+_124830217 12.184 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr4_+_24496434 12.088 ENSMUST00000108222.2
ENSMUST00000138567.2
ENSMUST00000050446.6
Mms22l


MMS22-like, DNA repair protein


chr3_+_51693771 12.083 ENSMUST00000099104.2
Gm10729
predicted gene 10729
chr2_+_124610573 12.025 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr12_+_38783455 11.970 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr1_-_190170671 11.950 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr1_+_106171752 11.947 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr18_-_12121460 11.882 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
Tmem241


transmembrane protein 241


chr15_+_25742314 11.880 ENSMUST00000135981.1
Myo10
myosin X
chr3_+_5218516 11.848 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr5_+_110330697 11.842 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr9_+_74976096 11.797 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr11_-_115808068 11.794 ENSMUST00000132780.1
Caskin2
CASK-interacting protein 2
chrX_+_151520655 11.778 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
Phf8


PHD finger protein 8


chr1_-_169531343 11.771 ENSMUST00000028000.7
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr2_+_73312601 11.742 ENSMUST00000090811.4
ENSMUST00000112050.1
Scrn3

secernin 3

chr7_+_90426312 11.695 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr7_-_102100227 11.689 ENSMUST00000106937.1
Art5
ADP-ribosyltransferase 5
chr19_+_5406815 11.684 ENSMUST00000174412.1
ENSMUST00000153017.2
4930481A15Rik

RIKEN cDNA 4930481A15 gene

chr13_+_104229366 11.639 ENSMUST00000022227.6
Cenpk
centromere protein K
chr1_-_171196229 11.637 ENSMUST00000111332.1
Pcp4l1
Purkinje cell protein 4-like 1
chr12_+_38783503 11.624 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr8_+_31111816 11.608 ENSMUST00000046941.7
Rnf122
ring finger protein 122
chr4_+_97777606 11.565 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
20.3 121.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
14.7 14.7 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
12.4 37.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
11.7 129.2 GO:0060539 diaphragm development(GO:0060539)
10.1 30.4 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
9.6 48.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
8.7 26.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
7.5 120.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
7.5 67.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
7.5 134.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
7.5 44.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
7.3 80.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
7.1 21.4 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
7.0 28.1 GO:0021698 cerebellar cortex structural organization(GO:0021698)
6.9 20.8 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
6.8 6.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
6.7 20.2 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
6.6 19.9 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
6.4 32.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
6.3 18.8 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
6.0 29.9 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
5.8 23.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
5.8 87.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
5.6 22.4 GO:0035262 gonad morphogenesis(GO:0035262)
5.6 27.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
5.3 69.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
5.2 15.7 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
5.2 15.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
5.2 56.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
5.1 30.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
5.0 10.0 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
5.0 54.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
4.5 31.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
4.4 39.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
4.3 34.1 GO:0015074 DNA integration(GO:0015074)
4.2 37.9 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
4.2 12.6 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
4.1 20.3 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
3.9 11.8 GO:0045004 DNA replication proofreading(GO:0045004)
3.9 35.4 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
3.8 11.5 GO:0042908 xenobiotic transport(GO:0042908)
3.8 15.3 GO:0060032 notochord regression(GO:0060032)
3.8 45.7 GO:0060013 righting reflex(GO:0060013)
3.7 11.0 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.6 10.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
3.6 17.9 GO:0015671 oxygen transport(GO:0015671)
3.5 21.3 GO:0036089 cleavage furrow formation(GO:0036089)
3.5 7.1 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
3.5 38.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
3.4 10.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
3.4 10.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
3.4 3.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
3.3 10.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
3.3 9.8 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
3.2 6.5 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
3.1 3.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
3.1 28.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
3.1 9.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
3.0 9.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
3.0 3.0 GO:1902730 positive regulation of proteoglycan biosynthetic process(GO:1902730)
3.0 9.0 GO:0060382 regulation of DNA strand elongation(GO:0060382)
2.9 5.8 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
2.8 8.5 GO:0006553 lysine metabolic process(GO:0006553)
2.8 16.9 GO:0003383 apical constriction(GO:0003383)
2.8 2.8 GO:1905066 regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
2.8 22.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
2.7 22.0 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
2.7 24.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
2.7 21.5 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
2.7 48.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
2.7 18.6 GO:0034770 histone H4-K20 methylation(GO:0034770)
2.6 7.9 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
2.6 10.5 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
2.6 13.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
2.6 7.9 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
2.6 57.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
2.6 23.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
2.5 20.3 GO:0072615 interleukin-17 secretion(GO:0072615)
2.5 2.5 GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
2.5 7.4 GO:0097350 neutrophil clearance(GO:0097350)
2.4 2.4 GO:0002643 regulation of tolerance induction(GO:0002643)
2.4 11.9 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038)
2.4 7.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
2.4 11.9 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
2.4 7.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
2.4 40.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
2.3 6.9 GO:0021546 rhombomere development(GO:0021546)
2.3 9.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
2.3 4.6 GO:0006566 threonine metabolic process(GO:0006566)
2.3 22.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
2.3 2.3 GO:0002827 regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827)
2.2 6.7 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
2.2 30.9 GO:0051451 myoblast migration(GO:0051451)
2.2 11.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
2.2 6.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
2.1 6.3 GO:2000096 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
2.1 22.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
2.0 16.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
2.0 14.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
2.0 8.1 GO:0006014 D-ribose metabolic process(GO:0006014)
2.0 5.9 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.9 32.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.9 7.6 GO:0071475 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
1.9 22.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
1.9 7.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.9 13.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174) mitotic DNA replication checkpoint(GO:0033314)
1.9 11.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.9 5.6 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
1.9 9.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
1.9 5.6 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
1.8 3.7 GO:0001661 conditioned taste aversion(GO:0001661)
1.8 12.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.8 12.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.8 49.4 GO:0006270 DNA replication initiation(GO:0006270)
1.8 7.2 GO:0006545 glycine biosynthetic process(GO:0006545)
1.8 16.0 GO:0071763 nuclear membrane organization(GO:0071763)
1.8 24.6 GO:0072189 ureter development(GO:0072189)
1.8 29.8 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
1.7 10.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.7 6.7 GO:0030043 actin filament fragmentation(GO:0030043)
1.7 5.0 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
1.7 8.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.6 3.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
1.6 11.3 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
1.6 4.8 GO:0021759 globus pallidus development(GO:0021759)
1.6 3.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.6 9.4 GO:0046719 regulation by virus of viral protein levels in host cell(GO:0046719)
1.5 6.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
1.5 15.5 GO:0060179 male mating behavior(GO:0060179)
1.5 13.8 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
1.5 6.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
1.5 46.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
1.5 4.4 GO:1903722 regulation of centriole elongation(GO:1903722)
1.5 8.9 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.5 5.9 GO:0072592 oxygen metabolic process(GO:0072592)
1.5 11.7 GO:0060235 lens induction in camera-type eye(GO:0060235)
1.5 1.5 GO:0032275 luteinizing hormone secretion(GO:0032275)
1.4 1.4 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
1.4 28.4 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
1.4 31.1 GO:1904355 positive regulation of telomere capping(GO:1904355)
1.4 7.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
1.4 7.0 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.4 14.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.4 2.8 GO:2000851 positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
1.4 2.8 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.4 1.4 GO:1904173 regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
1.4 4.1 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
1.4 2.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.4 5.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
1.4 5.4 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.4 4.1 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
1.3 14.7 GO:0001675 acrosome assembly(GO:0001675)
1.3 9.3 GO:0070423 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
1.3 5.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.3 3.9 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
1.3 9.0 GO:0015669 gas transport(GO:0015669) carbon dioxide transport(GO:0015670)
1.3 1.3 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
1.3 16.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
1.3 13.9 GO:0006228 UTP biosynthetic process(GO:0006228)
1.2 13.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
1.2 45.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.2 6.1 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) terpenoid biosynthetic process(GO:0016114)
1.2 4.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.2 7.1 GO:0034587 piRNA metabolic process(GO:0034587)
1.2 2.3 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
1.2 3.5 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.2 3.5 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) regulation of cardiac ventricle development(GO:1904412) positive regulation of cardiac ventricle development(GO:1904414)
1.1 6.8 GO:0009235 cobalamin metabolic process(GO:0009235)
1.1 2.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
1.1 5.5 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
1.1 19.7 GO:0046069 cGMP catabolic process(GO:0046069)
1.1 5.4 GO:1990839 response to endothelin(GO:1990839)
1.1 16.0 GO:0042407 cristae formation(GO:0042407)
1.1 4.2 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
1.1 3.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.0 3.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
1.0 3.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
1.0 2.0 GO:0000189 MAPK import into nucleus(GO:0000189)
1.0 1.0 GO:0060017 parathyroid gland development(GO:0060017)
1.0 8.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.0 3.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
1.0 5.0 GO:0051684 maintenance of Golgi location(GO:0051684)
1.0 4.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
1.0 2.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
1.0 51.0 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
1.0 23.0 GO:0034508 centromere complex assembly(GO:0034508)
1.0 14.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
1.0 8.9 GO:0036158 outer dynein arm assembly(GO:0036158)
1.0 3.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.0 3.9 GO:0009313 oligosaccharide catabolic process(GO:0009313)
1.0 2.9 GO:0060854 patterning of lymph vessels(GO:0060854)
1.0 3.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.9 14.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.9 2.8 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.9 2.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.9 4.6 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.9 3.6 GO:0030091 protein repair(GO:0030091)
0.9 3.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.9 2.6 GO:0097274 urea homeostasis(GO:0097274)
0.9 3.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.9 8.6 GO:0009404 toxin metabolic process(GO:0009404)
0.9 5.1 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.8 2.5 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.8 11.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.8 2.5 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.8 5.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.8 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.8 3.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.8 0.8 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.8 5.7 GO:0097475 motor neuron migration(GO:0097475)
0.8 1.6 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.8 13.0 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.8 32.4 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.8 7.9 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.8 2.3 GO:0060051 negative regulation of protein glycosylation(GO:0060051)
0.8 10.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.8 24.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.8 4.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.8 5.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.8 3.1 GO:0070269 pyroptosis(GO:0070269)
0.7 29.1 GO:0006284 base-excision repair(GO:0006284)
0.7 2.2 GO:0051593 response to folic acid(GO:0051593)
0.7 6.5 GO:0002377 immunoglobulin production(GO:0002377)
0.7 4.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.7 2.1 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) negative regulation of intestinal absorption(GO:1904479)
0.7 2.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.7 1.4 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.7 3.4 GO:0031642 negative regulation of myelination(GO:0031642)
0.7 3.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.7 21.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.7 2.7 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.7 6.7 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.7 3.3 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.7 4.0 GO:0001821 histamine secretion(GO:0001821)
0.7 5.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.7 12.5 GO:0031297 replication fork processing(GO:0031297)
0.6 4.5 GO:0071294 cellular response to zinc ion(GO:0071294)
0.6 5.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.6 1.3 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.6 20.3 GO:0043171 peptide catabolic process(GO:0043171)
0.6 1.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.6 3.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.6 8.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.6 0.6 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.6 10.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.6 0.6 GO:0001787 natural killer cell proliferation(GO:0001787)
0.6 12.5 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.6 8.2 GO:0048368 lateral mesoderm development(GO:0048368)
0.6 2.3 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.6 1.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.6 0.6 GO:0007113 endomitotic cell cycle(GO:0007113)
0.6 11.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.6 1.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.6 2.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.6 1.1 GO:0016093 polyprenol metabolic process(GO:0016093)
0.6 2.2 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.6 2.2 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.5 3.2 GO:0015879 carnitine transport(GO:0015879)
0.5 4.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.5 2.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.5 1.6 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.5 5.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.5 2.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.5 1.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.5 1.5 GO:0072675 osteoclast fusion(GO:0072675)
0.5 3.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.5 1.0 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.5 2.5 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.5 6.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.5 2.4 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.5 2.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.5 5.8 GO:0002385 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.5 9.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.5 1.5 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.5 2.9 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.5 7.2 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.5 9.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.5 6.2 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.5 1.4 GO:0030224 monocyte differentiation(GO:0030224)
0.5 2.4 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.5 2.8 GO:1900225 NLRP3 inflammasome complex assembly(GO:0044546) regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.5 4.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.5 4.6 GO:0019730 antimicrobial humoral response(GO:0019730)
0.5 4.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.4 3.6 GO:0006527 arginine catabolic process(GO:0006527)
0.4 1.3 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.4 4.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.4 3.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 7.8 GO:0042832 defense response to protozoan(GO:0042832)
0.4 3.0 GO:0009249 protein lipoylation(GO:0009249)
0.4 2.1 GO:0071472 cellular response to salt stress(GO:0071472)
0.4 6.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.4 3.4 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.4 2.5 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.4 3.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.4 5.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.4 1.7 GO:1904714 chaperone-mediated autophagy(GO:0061684) regulation of chaperone-mediated autophagy(GO:1904714) negative regulation of chaperone-mediated autophagy(GO:1904715)
0.4 4.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.4 1.2 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.4 1.6 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.4 5.2 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.4 1.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.4 4.0 GO:0043144 snoRNA processing(GO:0043144)
0.4 1.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.4 17.7 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.4 5.1 GO:1990403 embryonic brain development(GO:1990403)
0.4 1.9 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.4 3.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.4 8.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.4 3.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 3.5 GO:0006833 water transport(GO:0006833)
0.4 5.4 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.4 2.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.4 6.5 GO:0030033 microvillus assembly(GO:0030033)
0.4 12.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.4 9.9 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.4 1.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 7.2 GO:0044804 nucleophagy(GO:0044804)
0.4 7.5 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.4 8.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.4 5.5 GO:0007379 segment specification(GO:0007379)
0.4 0.7 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.4 30.8 GO:0007052 mitotic spindle organization(GO:0007052)
0.4 0.7 GO:0032687 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.4 3.6 GO:0048664 neuron fate determination(GO:0048664)
0.4 1.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.4 3.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 11.7 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.3 1.0 GO:0006001 fructose catabolic process(GO:0006001) response to sucrose(GO:0009744) response to disaccharide(GO:0034285) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.3 5.8 GO:0001779 natural killer cell differentiation(GO:0001779)
0.3 2.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3 2.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 12.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 1.0 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.3 0.6 GO:0090656 t-circle formation(GO:0090656)
0.3 1.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 3.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.3 1.0 GO:1902527 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) positive regulation of protein monoubiquitination(GO:1902527)
0.3 3.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 1.6 GO:0060406 positive regulation of penile erection(GO:0060406)
0.3 2.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 1.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.3 1.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 4.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.3 1.2 GO:0040031 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.3 10.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.3 2.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 3.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.3 8.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 1.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 2.9 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.3 1.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3 3.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.3 0.8 GO:0019372 lipoxygenase pathway(GO:0019372)
0.3 2.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.3 1.6 GO:0006983 ER overload response(GO:0006983)
0.3 10.6 GO:0030901 midbrain development(GO:0030901)
0.3 1.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.3 2.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.3 3.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.3 4.1 GO:0021884 forebrain neuron development(GO:0021884)
0.3 2.3 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.3 1.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 1.5 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 1.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 2.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.3 2.5 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 5.5 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.2 3.6 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.2 11.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 4.1 GO:0015693 magnesium ion transport(GO:0015693)
0.2 13.8 GO:0051289 protein homotetramerization(GO:0051289)
0.2 1.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 4.2 GO:0009409 response to cold(GO:0009409)
0.2 1.4 GO:0042182 ketone catabolic process(GO:0042182)
0.2 2.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 3.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 0.7 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.2 0.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 2.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.2 1.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 1.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 2.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 3.6 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.2 4.0 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.2 1.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 0.6 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.2 5.0 GO:0051225 spindle assembly(GO:0051225)
0.2 10.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.2 11.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 0.6 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.2 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 1.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.2 4.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.2 3.2 GO:0006825 copper ion transport(GO:0006825)
0.2 1.7 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 1.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
0.2 2.8 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.2 1.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.9 GO:1902592 viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.2 0.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 6.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 1.3 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 1.1 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 4.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 3.2 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.2 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 4.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.2 1.1 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.2 4.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 3.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 0.5 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.2 4.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 3.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.9 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.3 GO:0036035 osteoclast development(GO:0036035)
0.1 4.3 GO:0035329 hippo signaling(GO:0035329)
0.1 4.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.7 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 3.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 11.3 GO:0051028 mRNA transport(GO:0051028)
0.1 1.3 GO:0007398 ectoderm development(GO:0007398)
0.1 1.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 8.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 2.8 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.1 0.6 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.5 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:0015817 histidine transport(GO:0015817)
0.1 0.2 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 4.1 GO:0042742 defense response to bacterium(GO:0042742)
0.1 0.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 6.1 GO:0007601 visual perception(GO:0007601)
0.1 1.3 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.2 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 6.8 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)
0.1 0.2 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 0.9 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 1.6 GO:0060420 regulation of cardiac muscle tissue growth(GO:0055021) regulation of heart growth(GO:0060420)
0.1 0.5 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 4.1 GO:0009060 aerobic respiration(GO:0009060)
0.1 2.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.3 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 2.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 2.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 1.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 3.3 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.6 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 1.6 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 11.4 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.8 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.3 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 1.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.2 GO:0021591 ventricular system development(GO:0021591)
0.1 0.2 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.9 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.2 GO:0038202 TORC1 signaling(GO:0038202)
0.0 1.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 1.0 GO:0007286 spermatid development(GO:0007286)
0.0 0.4 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.3 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 2.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
25.6 128.2 GO:0097149 centralspindlin complex(GO:0097149)
16.9 50.8 GO:0070557 PCNA-p21 complex(GO:0070557)
9.7 58.3 GO:0031262 Ndc80 complex(GO:0031262)
9.0 80.8 GO:0030478 actin cap(GO:0030478)
7.2 7.2 GO:0070552 BRISC complex(GO:0070552)
7.2 21.5 GO:0000799 nuclear condensin complex(GO:0000799)
6.8 20.5 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
6.3 37.9 GO:0070531 BRCA1-A complex(GO:0070531)
4.4 13.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
4.4 47.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
4.3 21.3 GO:0032133 chromosome passenger complex(GO:0032133)
4.1 4.1 GO:0042585 germinal vesicle(GO:0042585)
4.1 16.3 GO:0008623 CHRAC(GO:0008623)
4.0 12.1 GO:0035101 FACT complex(GO:0035101)
3.7 11.0 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
3.1 30.7 GO:0001939 female pronucleus(GO:0001939)
2.9 17.7 GO:0000235 astral microtubule(GO:0000235)
2.9 8.8 GO:0005588 collagen type V trimer(GO:0005588)
2.9 26.0 GO:0036157 outer dynein arm(GO:0036157)
2.9 20.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
2.6 7.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
2.6 10.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
2.4 12.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
2.4 26.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
2.3 14.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
2.1 8.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.0 4.0 GO:0001739 sex chromatin(GO:0001739)
2.0 17.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.9 7.6 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.9 19.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.8 27.5 GO:0042788 polysomal ribosome(GO:0042788)
1.8 12.7 GO:0000796 condensin complex(GO:0000796)
1.8 7.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.8 16.0 GO:0061617 MICOS complex(GO:0061617)
1.8 47.3 GO:0051233 spindle midzone(GO:0051233)
1.5 10.7 GO:0070187 telosome(GO:0070187)
1.5 4.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.5 18.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
1.4 4.2 GO:0035861 site of double-strand break(GO:0035861)
1.4 7.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
1.4 4.1 GO:0001674 female germ cell nucleus(GO:0001674)
1.4 2.8 GO:0033010 paranodal junction(GO:0033010)
1.4 5.5 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
1.3 2.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.3 47.0 GO:0035371 microtubule plus-end(GO:0035371)
1.3 8.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.3 16.9 GO:0043219 lateral loop(GO:0043219)
1.3 6.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.3 3.9 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
1.2 2.4 GO:0044753 amphisome(GO:0044753)
1.2 4.9 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
1.2 7.1 GO:0030896 checkpoint clamp complex(GO:0030896)
1.2 5.8 GO:0033553 rDNA heterochromatin(GO:0033553)
1.1 3.3 GO:0034657 GID complex(GO:0034657)
1.1 5.6 GO:0035189 Rb-E2F complex(GO:0035189)
1.1 8.7 GO:0070419 nonhomologous end joining complex(GO:0070419)
1.1 28.3 GO:0016363 nuclear matrix(GO:0016363)
1.1 19.4 GO:0035102 PRC1 complex(GO:0035102)
1.0 1.0 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
1.0 10.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.0 7.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
1.0 23.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.0 10.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.9 56.4 GO:0016459 myosin complex(GO:0016459)
0.8 2.5 GO:0070939 Dsl1p complex(GO:0070939)
0.8 10.8 GO:0042555 MCM complex(GO:0042555)
0.8 4.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.8 1.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.8 10.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.8 4.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.8 4.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.8 58.7 GO:0005902 microvillus(GO:0005902)
0.8 3.1 GO:0061702 inflammasome complex(GO:0061702)
0.7 3.7 GO:0000798 nuclear cohesin complex(GO:0000798)
0.7 4.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.7 5.7 GO:0070652 HAUS complex(GO:0070652)
0.7 9.3 GO:0097542 ciliary tip(GO:0097542)
0.7 9.2 GO:0031209 SCAR complex(GO:0031209)
0.7 16.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.7 29.6 GO:0005876 spindle microtubule(GO:0005876)
0.7 10.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.7 7.9 GO:0061700 GATOR2 complex(GO:0061700)
0.7 2.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 3.8 GO:0070847 core mediator complex(GO:0070847)
0.6 4.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.6 1.9 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.6 2.5 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.6 9.9 GO:0032156 septin cytoskeleton(GO:0032156)
0.6 2.4 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.6 19.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.6 13.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.6 28.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.6 2.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.6 14.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.5 52.0 GO:0032993 protein-DNA complex(GO:0032993)
0.5 5.3 GO:0010369 chromocenter(GO:0010369)
0.5 8.2 GO:0016580 Sin3 complex(GO:0016580)
0.5 76.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.5 2.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5 5.8 GO:0042581 specific granule(GO:0042581)
0.5 0.5 GO:0097422 tubular endosome(GO:0097422)
0.5 4.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.5 27.6 GO:0005844 polysome(GO:0005844)
0.4 4.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 4.4 GO:0090543 Flemming body(GO:0090543)
0.4 6.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.4 5.2 GO:0042101 T cell receptor complex(GO:0042101)
0.4 3.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 48.1 GO:0000776 kinetochore(GO:0000776)
0.4 3.0 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.4 134.1 GO:0016607 nuclear speck(GO:0016607)
0.4 2.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 2.3 GO:0070545 PeBoW complex(GO:0070545)
0.4 59.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 35.4 GO:0005814 centriole(GO:0005814)
0.4 4.8 GO:0016589 NURF complex(GO:0016589)
0.4 5.5 GO:0017119 Golgi transport complex(GO:0017119)
0.4 3.9 GO:0043596 nuclear replication fork(GO:0043596)
0.4 6.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 5.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.4 21.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 5.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.3 7.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 3.1 GO:0000813 ESCRT I complex(GO:0000813)
0.3 10.4 GO:0001772 immunological synapse(GO:0001772)
0.3 4.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 15.1 GO:0031519 PcG protein complex(GO:0031519)
0.3 1.9 GO:0030914 STAGA complex(GO:0030914)
0.3 1.6 GO:0071141 SMAD protein complex(GO:0071141)
0.3 7.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 5.3 GO:0002080 acrosomal membrane(GO:0002080)
0.3 1.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.3 4.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 4.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.3 5.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 8.1 GO:0002102 podosome(GO:0002102)
0.3 3.0 GO:0000800 lateral element(GO:0000800)
0.2 3.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 1.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.2 2.1 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.2 1.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 2.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.2 3.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 17.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 5.2 GO:0032420 stereocilium(GO:0032420)
0.2 2.2 GO:0031931 TORC1 complex(GO:0031931)
0.2 2.0 GO:0043194 axon initial segment(GO:0043194)
0.2 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.2 3.9 GO:0000922 spindle pole(GO:0000922)
0.2 7.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 5.8 GO:0043195 terminal bouton(GO:0043195)
0.2 1.3 GO:0089701 U2AF(GO:0089701)
0.2 18.0 GO:0005681 spliceosomal complex(GO:0005681)
0.2 9.2 GO:0043034 costamere(GO:0043034)
0.2 2.7 GO:0035253 ciliary rootlet(GO:0035253)
0.2 0.6 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 2.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 4.0 GO:0001891 phagocytic cup(GO:0001891)
0.2 11.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 3.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.5 GO:0030061 mitochondrial crista(GO:0030061)
0.2 7.3 GO:0014704 intercalated disc(GO:0014704)
0.2 373.7 GO:0005654 nucleoplasm(GO:0005654)
0.2 0.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 0.9 GO:0071986 Ragulator complex(GO:0071986)
0.2 3.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 1.0 GO:0097342 ripoptosome(GO:0097342)
0.2 1.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 1.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 5.0 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.1 7.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 2.8 GO:0005871 kinesin complex(GO:0005871)
0.1 1.9 GO:0030904 retromer complex(GO:0030904)
0.1 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.0 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 3.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 297.2 GO:0005634 nucleus(GO:0005634)
0.1 4.1 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 0.4 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.1 2.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 3.9 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.3 GO:0099503 secretory vesicle(GO:0099503)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.5 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850) eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
21.7 65.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
16.9 50.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
10.0 29.9 GO:0042936 dipeptide transporter activity(GO:0042936)
8.7 26.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
8.2 57.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
6.7 20.2 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
6.3 18.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
6.1 24.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
5.7 85.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
5.6 28.2 GO:0000405 bubble DNA binding(GO:0000405)
5.2 15.7 GO:0016015 morphogen activity(GO:0016015)
5.2 25.8 GO:0035174 histone serine kinase activity(GO:0035174)
5.1 40.9 GO:0050693 LBD domain binding(GO:0050693)
5.0 19.8 GO:0008142 oxysterol binding(GO:0008142)
4.1 12.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
3.9 11.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
3.9 11.7 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
3.6 18.2 GO:0004594 pantothenate kinase activity(GO:0004594)
3.6 17.9 GO:0005344 oxygen transporter activity(GO:0005344)
3.6 21.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
3.3 9.8 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
3.2 12.8 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
3.2 31.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
3.1 9.4 GO:0005118 sevenless binding(GO:0005118)
3.0 9.0 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
2.9 20.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
2.9 11.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
2.8 48.1 GO:0051010 microtubule plus-end binding(GO:0051010)
2.7 11.0 GO:0043515 kinetochore binding(GO:0043515)
2.7 10.6 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.6 10.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
2.6 12.9 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
2.6 10.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
2.5 47.7 GO:0070410 co-SMAD binding(GO:0070410)
2.5 7.4 GO:0032052 bile acid binding(GO:0032052)
2.5 29.6 GO:0070888 E-box binding(GO:0070888)
2.4 43.5 GO:0045295 gamma-catenin binding(GO:0045295)
2.4 16.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
2.4 7.2 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
2.4 9.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
2.3 21.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
2.3 7.0 GO:0030156 benzodiazepine receptor binding(GO:0030156)
2.3 14.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
2.3 4.6 GO:0070905 serine binding(GO:0070905)
2.3 22.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
2.2 6.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
2.2 44.0 GO:0030215 semaphorin receptor binding(GO:0030215)
2.2 8.6 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
2.1 10.6 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
2.0 7.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
2.0 5.9 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
2.0 9.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.9 15.5 GO:0046790 virion binding(GO:0046790)
1.9 59.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.9 17.2 GO:0008420 CTD phosphatase activity(GO:0008420)
1.9 5.7 GO:0043426 MRF binding(GO:0043426)
1.9 7.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.9 14.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.9 20.4 GO:0048185 activin binding(GO:0048185)
1.8 23.6 GO:0035198 miRNA binding(GO:0035198)
1.8 7.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
1.8 26.3 GO:0016805 dipeptidase activity(GO:0016805)
1.7 6.9 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
1.7 16.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
1.7 18.4 GO:0015250 water channel activity(GO:0015250)
1.7 14.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.6 9.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.6 4.7 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
1.6 7.9 GO:0042289 MHC class II protein binding(GO:0042289)
1.6 277.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.6 14.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
1.5 6.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
1.5 28.6 GO:0001222 transcription corepressor binding(GO:0001222)
1.5 5.9 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.4 46.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.4 23.4 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
1.4 5.4 GO:0048408 epidermal growth factor binding(GO:0048408)
1.3 5.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.3 7.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.2 12.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
1.2 4.8 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
1.2 2.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.2 9.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.2 3.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
1.1 10.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
1.1 3.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
1.1 13.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.1 17.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
1.1 5.5 GO:0004849 uridine kinase activity(GO:0004849)
1.1 1.1 GO:0008502 melatonin receptor activity(GO:0008502)
1.1 17.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.1 3.2 GO:0005124 scavenger receptor binding(GO:0005124)
1.1 10.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
1.0 4.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
1.0 11.1 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.0 17.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
1.0 3.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
1.0 122.5 GO:0017048 Rho GTPase binding(GO:0017048)
1.0 8.8 GO:0005540 hyaluronic acid binding(GO:0005540)
1.0 24.3 GO:0070840 dynein complex binding(GO:0070840)
1.0 2.9 GO:0071633 dihydroceramidase activity(GO:0071633)
1.0 3.8 GO:0004645 phosphorylase activity(GO:0004645)
0.9 2.8 GO:0048019 receptor antagonist activity(GO:0048019)
0.9 13.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.9 2.8 GO:0004966 galanin receptor activity(GO:0004966)
0.9 4.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.9 5.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.9 17.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.9 34.7 GO:0001671 ATPase activator activity(GO:0001671)
0.9 5.1 GO:0005042 netrin receptor activity(GO:0005042)
0.9 4.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.9 6.0 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.9 9.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.8 7.6 GO:0070700 BMP receptor binding(GO:0070700)
0.8 2.5 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.8 86.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.8 3.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.8 5.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.8 10.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.8 26.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.8 4.8 GO:0001849 complement component C1q binding(GO:0001849)
0.8 71.8 GO:0003774 motor activity(GO:0003774)
0.8 18.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.8 3.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.8 3.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.8 14.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.8 4.6 GO:0070728 leucine binding(GO:0070728)
0.8 3.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.7 12.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.7 2.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.7 40.8 GO:0003684 damaged DNA binding(GO:0003684)
0.7 35.7 GO:0001047 core promoter binding(GO:0001047)
0.7 25.7 GO:0017091 AU-rich element binding(GO:0017091)
0.7 3.5 GO:0051425 PTB domain binding(GO:0051425)
0.7 13.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.7 2.1 GO:0004568 chitinase activity(GO:0004568)
0.7 3.5 GO:0098821 BMP receptor activity(GO:0098821)
0.7 3.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.7 7.6 GO:0008430 selenium binding(GO:0008430)
0.7 1.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.7 2.0 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.7 7.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.7 8.0 GO:0050897 cobalt ion binding(GO:0050897)
0.7 22.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.7 2.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.7 28.7 GO:0005158 insulin receptor binding(GO:0005158)
0.6 1.9 GO:0017040 ceramidase activity(GO:0017040)
0.6 25.7 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.6 1.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 2.5 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.6 10.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.6 1.9 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.6 27.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6 4.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.6 3.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.6 2.4 GO:0008301 DNA binding, bending(GO:0008301)
0.6 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.6 5.8 GO:0008097 5S rRNA binding(GO:0008097)
0.6 3.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.6 2.3 GO:0003680 AT DNA binding(GO:0003680)
0.6 6.2 GO:0035497 cAMP response element binding(GO:0035497)
0.6 2.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.6 24.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 1.6 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.5 8.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.5 8.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.5 4.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.5 2.7 GO:0016918 retinal binding(GO:0016918)
0.5 1.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.5 1.6 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.5 1.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.5 3.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.5 1.5 GO:0071568 UFM1 transferase activity(GO:0071568)
0.5 3.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.5 6.0 GO:0043495 protein anchor(GO:0043495)
0.5 10.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 3.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.5 20.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.5 1.4 GO:0016531 copper chaperone activity(GO:0016531)
0.5 1.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.5 5.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 3.3 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.5 2.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.5 7.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.5 33.5 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.5 2.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4 7.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.4 5.7 GO:0070513 death domain binding(GO:0070513)
0.4 13.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 1.3 GO:0004875 complement receptor activity(GO:0004875)
0.4 2.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 9.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.4 36.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 3.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.4 2.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 4.8 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.4 8.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 5.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.4 1.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.4 1.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.4 2.7 GO:0051920 peroxiredoxin activity(GO:0051920)
0.4 7.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.4 21.5 GO:0035064 methylated histone binding(GO:0035064)
0.4 1.5 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.4 4.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 2.5 GO:0071253 connexin binding(GO:0071253)
0.4 1.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 1.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.4 5.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 51.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.3 3.1 GO:0044548 S100 protein binding(GO:0044548)
0.3 1.0 GO:0004454 ketohexokinase activity(GO:0004454)
0.3 5.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 4.1 GO:0031996 thioesterase binding(GO:0031996)
0.3 8.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 1.0 GO:0008527 taste receptor activity(GO:0008527)
0.3 1.3 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.3 2.3 GO:1990405 protein antigen binding(GO:1990405)
0.3 9.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 4.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.3 0.3 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.3 3.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 9.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 6.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 3.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.3 15.5 GO:0002039 p53 binding(GO:0002039)
0.3 7.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 6.3 GO:0030506 ankyrin binding(GO:0030506)
0.3 1.4 GO:0034235 GPI anchor binding(GO:0034235)
0.3 2.2 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.3 1.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 2.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 1.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 1.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.7 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 4.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 7.7 GO:0042169 SH2 domain binding(GO:0042169)
0.2 18.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 3.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 0.7 GO:0031208 POZ domain binding(GO:0031208)
0.2 2.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 10.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.2 5.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.2 4.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 2.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 5.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 1.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.2 0.6 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 5.1 GO:0032452 histone demethylase activity(GO:0032452)
0.2 2.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 1.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 0.6 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 4.3 GO:0031491 nucleosome binding(GO:0031491)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 5.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 3.5 GO:0016849 guanylate cyclase activity(GO:0004383) phosphorus-oxygen lyase activity(GO:0016849)
0.2 1.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 1.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 25.5 GO:0051015 actin filament binding(GO:0051015)
0.2 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.2 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.7 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.2 1.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 1.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.2 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 2.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 35.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 1.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 2.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 23.3 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2 5.2 GO:0030145 manganese ion binding(GO:0030145)
0.2 1.5 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.2 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 4.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 33.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 0.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 2.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0019863 IgE binding(GO:0019863)
0.1 30.3 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 2.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 4.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 3.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 1.8 GO:0015923 mannosidase activity(GO:0015923)
0.1 3.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 3.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 7.7 GO:0042393 histone binding(GO:0042393)
0.1 1.1 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.1 1.8 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 2.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0005506 iron ion binding(GO:0005506)
0.1 0.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.8 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.0 GO:0004386 helicase activity(GO:0004386)
0.1 24.4 GO:0005525 GTP binding(GO:0005525)
0.1 2.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 2.7 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 0.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.0 GO:0030332 cyclin binding(GO:0030332)
0.1 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 70.3 GO:0003676 nucleic acid binding(GO:0003676)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.7 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 50.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
4.1 20.4 PID_ALK1_PATHWAY ALK1 signaling events
3.8 53.7 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
2.5 129.8 PID_PLK1_PATHWAY PLK1 signaling events
2.4 117.4 PID_AURORA_B_PATHWAY Aurora B signaling
2.3 6.9 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.7 52.8 PID_MYC_PATHWAY C-MYC pathway
1.6 164.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
1.6 54.9 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
1.5 73.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
1.4 71.0 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
1.3 11.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
1.2 3.6 ST_STAT3_PATHWAY STAT3 Pathway
1.2 23.5 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.1 37.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
1.0 11.2 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.9 37.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.8 18.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.8 4.1 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.8 21.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.8 12.2 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.8 17.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.7 6.7 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.7 47.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.7 13.0 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.7 1.4 PID_IL3_PATHWAY IL3-mediated signaling events
0.7 14.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.7 7.6 PID_ALK2_PATHWAY ALK2 signaling events
0.7 26.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.6 20.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.5 22.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.5 13.9 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.5 9.4 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.5 15.7 PID_ATR_PATHWAY ATR signaling pathway
0.5 18.1 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.5 15.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.5 3.7 PID_IL23_PATHWAY IL23-mediated signaling events
0.5 17.5 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.5 5.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.5 10.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.4 5.7 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.4 9.1 PID_REELIN_PATHWAY Reelin signaling pathway
0.4 10.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.3 7.9 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.3 2.1 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.3 6.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 22.1 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.3 3.7 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.3 9.7 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.3 5.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 7.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.2 8.5 PID_BMP_PATHWAY BMP receptor signaling
0.2 11.8 PID_NOTCH_PATHWAY Notch signaling pathway
0.2 2.4 PID_IL1_PATHWAY IL1-mediated signaling events
0.2 5.1 PID_BARD1_PATHWAY BARD1 signaling events
0.2 10.5 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 3.3 PID_ATM_PATHWAY ATM pathway
0.2 4.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 2.4 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.2 23.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 5.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 18.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 1.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 3.5 NABA_COLLAGENS Genes encoding collagen proteins
0.1 1.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.1 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.5 PID_CERAMIDE_PATHWAY Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 47.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
5.1 86.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
4.3 63.9 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
3.1 82.6 REACTOME_KINESINS Genes involved in Kinesins
2.6 49.9 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
2.3 49.0 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
2.3 97.5 REACTOME_G1_PHASE Genes involved in G1 Phase
2.3 86.2 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
2.0 196.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
1.9 29.0 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
1.8 29.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.8 20.2 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.7 10.4 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.7 28.5 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
1.7 53.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
1.6 6.5 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.6 125.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
1.5 5.9 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
1.4 11.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.4 24.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
1.4 21.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
1.2 8.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.2 29.0 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
1.1 32.3 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
1.1 40.4 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
1.0 14.1 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.0 7.9 REACTOME_PI3K_AKT_ACTIVATION Genes involved in PI3K/AKT activation
0.9 10.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.9 13.1 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.9 51.5 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.9 6.3 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.9 12.3 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.7 23.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.7 6.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.7 4.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.6 5.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 31.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.6 9.0 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.6 7.4 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.6 7.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.6 9.9 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.6 15.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.6 1.7 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.5 22.3 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.5 5.2 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.5 5.0 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 1.8 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.4 3.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 3.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 21.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 7.1 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.4 7.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.4 3.1 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 8.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 6.4 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.4 13.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 1.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.3 13.4 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.3 3.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 1.6 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 2.4 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.3 9.8 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.3 5.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 1.0 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.3 5.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 3.9 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 2.4 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 1.4 REACTOME_IL_3_5_AND_GM_CSF_SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.2 6.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 6.3 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.2 3.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.2 5.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 12.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 2.6 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.2 3.0 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 3.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.2 10.5 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 4.1 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.2 1.3 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.2 2.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 6.8 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 1.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.8 REACTOME_SIGNALLING_TO_RAS Genes involved in Signalling to RAS
0.1 2.8 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.5 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.1 8.7 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 1.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 4.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.2 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.0 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.9 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.2 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.5 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.5 REACTOME_METABOLISM_OF_CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 4.5 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 2.8 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 1.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.2 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER Genes involved in Transcription-coupled NER (TC-NER)
0.0 1.4 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex