Motif ID: Foxj3_Tbl1xr1

Z-value: 1.237

Transcription factors associated with Foxj3_Tbl1xr1:

Gene SymbolEntrez IDGene Name
Foxj3 ENSMUSG00000032998.10 Foxj3
Tbl1xr1 ENSMUSG00000027630.8 Tbl1xr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj3mm10_v2_chr4_+_119539652_1195396980.181.2e-01Click!
Tbl1xr1mm10_v2_chr3_+_22076644_220766810.047.2e-01Click!


Activity profile for motif Foxj3_Tbl1xr1.

activity profile for motif Foxj3_Tbl1xr1


Sorted Z-values histogram for motif Foxj3_Tbl1xr1

Sorted Z-values for motif Foxj3_Tbl1xr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxj3_Tbl1xr1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 7.993 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893127 7.944 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_144893077 7.782 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr8_-_53638945 6.994 ENSMUST00000047768.4
 Neil3
nei like 3 (E. coli)
chr15_+_57694651 6.961 ENSMUST00000096430.4
 Zhx2
zinc fingers and homeoboxes 2
chr4_+_128846163 6.744 ENSMUST00000138291.1
 Gm12968
predicted gene 12968
chr5_+_134932351 6.410 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
 Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr3_-_116968969 6.280 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr1_-_55226768 5.992 ENSMUST00000027121.8
ENSMUST00000114428.2
 Rftn2

raftlin family member 2

chr13_-_23430826 5.791 ENSMUST00000153753.1
ENSMUST00000141543.1
 C230035I16Rik

RIKEN cDNA C230035I16 gene

chr7_+_66365905 5.757 ENSMUST00000107486.1
 Gm10974
predicted gene 10974
chr10_-_130280218 5.754 ENSMUST00000061571.3
 Neurod4
neurogenic differentiation 4
chr4_+_11704439 5.749 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr6_+_138140298 5.664 ENSMUST00000008684.4
 Mgst1
microsomal glutathione S-transferase 1
chr5_-_99252839 5.625 ENSMUST00000168092.1
ENSMUST00000031276.8
 Rasgef1b

RasGEF domain family, member 1B

chr4_-_110290884 5.437 ENSMUST00000142722.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_-_33942111 5.234 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
 Gm13403


predicted gene 13403


chr4_+_97777606 5.153 ENSMUST00000075448.6
ENSMUST00000092532.6
 Nfia

nuclear factor I/A

chr9_-_58313189 5.109 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr6_+_141524379 5.069 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 943 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 31.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 20.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
2.0 12.0 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.7 11.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.7 10.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.4 10.3 GO:0031297 replication fork processing(GO:0031297)
2.5 10.1 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.9 10.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.8 9.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 8.8 GO:0010842 retina layer formation(GO:0010842)
2.8 8.4 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 8.1 GO:0043488 regulation of mRNA stability(GO:0043488)
1.6 7.9 GO:0034421 post-translational protein acetylation(GO:0034421)
1.3 7.5 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.9 7.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.7 7.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.8 7.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.4 7.2 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.5 7.1 GO:0072189 ureter development(GO:0072189)
0.3 7.1 GO:0070207 protein homotrimerization(GO:0070207)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 333 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 16.7 GO:0016459 myosin complex(GO:0016459)
0.2 14.7 GO:0005814 centriole(GO:0005814)
0.1 14.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 14.2 GO:0032993 protein-DNA complex(GO:0032993)
1.2 13.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 12.8 GO:0051233 spindle midzone(GO:0051233)
0.1 11.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 10.9 GO:0005667 transcription factor complex(GO:0005667)
1.7 10.3 GO:0031262 Ndc80 complex(GO:0031262)
0.7 10.0 GO:0042788 polysomal ribosome(GO:0042788)
1.0 9.1 GO:0030478 actin cap(GO:0030478)
0.2 8.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 8.1 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.3 7.8 GO:0035371 microtubule plus-end(GO:0035371)
0.2 7.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.6 7.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.9 7.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.8 7.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.4 7.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 6.8 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 534 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 43.7 GO:0003677 DNA binding(GO:0003677)
0.0 35.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2 33.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
3.8 26.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 19.8 GO:0003774 motor activity(GO:0003774)
0.8 19.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 12.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 12.4 GO:0042393 histone binding(GO:0042393)
3.0 12.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.5 10.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.1 9.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 9.5 GO:0042605 peptide antigen binding(GO:0042605)
0.5 9.2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.8 9.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 9.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.7 8.5 GO:0050693 LBD domain binding(GO:0050693)
0.1 8.5 GO:0004386 helicase activity(GO:0004386)
0.4 7.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
1.3 7.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.5 7.5 GO:0000405 bubble DNA binding(GO:0000405)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 34.1 PID_PLK1_PATHWAY PLK1 signaling events
0.4 23.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 16.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.4 16.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.2 15.6 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 12.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 9.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 8.6 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.2 7.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 7.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 6.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.3 6.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 6.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.2 5.9 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 5.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 4.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.2 4.8 PID_BARD1_PATHWAY BARD1 signaling events
0.2 4.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 4.5 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 143 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 52.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.5 12.7 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 10.0 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.4 9.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.4 9.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.3 8.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 7.9 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.4 7.6 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 7.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 7.2 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.1 7.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.5 6.5 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
1.0 6.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 6.0 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4 5.9 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 5.9 REACTOME_KINESINS Genes involved in Kinesins
0.1 5.9 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 5.5 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.6 5.1 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 5.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination