Motif ID: Foxm1

Z-value: 0.796


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_128363058-0.132.6e-01Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_65845833 8.764 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_65845767 8.072 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr18_+_67133713 6.266 ENSMUST00000076605.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr15_+_98167806 6.238 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr19_+_25672408 5.729 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chrX_-_141725181 5.103 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chrX_+_164373363 4.798 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr12_-_40037387 4.358 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr8_+_58912257 4.261 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr1_-_79440039 4.056 ENSMUST00000049972.4
Scg2
secretogranin II
chr18_+_36952621 3.692 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr4_-_36136463 3.536 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr18_-_62741387 3.289 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr6_-_59024340 3.257 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr7_-_19921139 3.218 ENSMUST00000043517.7
Pvr
poliovirus receptor
chr9_-_100571049 3.155 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr3_+_134828993 3.043 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr2_+_136052180 3.035 ENSMUST00000144403.1
Lamp5
lysosomal-associated membrane protein family, member 5
chr1_-_138842429 2.946 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr4_-_15149755 2.914 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr14_-_5455467 2.894 ENSMUST00000180867.1
Gm3194
predicted gene 3194
chr6_+_142413441 2.803 ENSMUST00000088263.4
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr10_+_94576254 2.616 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr6_+_142413833 2.515 ENSMUST00000126521.2
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr6_+_142414012 2.499 ENSMUST00000141548.1
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr10_-_63927434 2.411 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr9_-_75597643 2.327 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr11_-_42000284 2.169 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr8_-_36732897 2.168 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr10_+_90829780 1.859 ENSMUST00000179337.2
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_90829835 1.834 ENSMUST00000179964.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_+_68117713 1.779 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr11_-_42000532 1.715 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr19_-_58455161 1.680 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr10_-_116972609 1.614 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr7_+_31059342 1.609 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr2_+_96318014 1.580 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr9_-_121839460 1.491 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr7_-_30072801 1.471 ENSMUST00000183115.1
ENSMUST00000182919.1
ENSMUST00000183190.1
ENSMUST00000080834.8
Zfp82



zinc finger protein 82



chr10_+_112928501 1.465 ENSMUST00000180464.1
Gm26596
predicted gene, 26596
chr5_+_137553517 1.442 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chr5_-_125390176 1.436 ENSMUST00000156249.1
Ubc
ubiquitin C
chr1_+_74713551 1.373 ENSMUST00000027356.5
Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr6_+_142387215 1.302 ENSMUST00000032372.6
Golt1b
golgi transport 1 homolog B (S. cerevisiae)
chr13_+_55209776 1.275 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr2_+_138278481 1.269 ENSMUST00000075410.4
Btbd3
BTB (POZ) domain containing 3
chr8_+_34807287 1.264 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr19_-_58455398 1.244 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr2_+_104095796 1.237 ENSMUST00000040423.5
ENSMUST00000168176.1
Cd59a

CD59a antigen

chr10_-_20725023 1.226 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr9_+_3532295 1.207 ENSMUST00000115733.1
Gucy1a2
guanylate cyclase 1, soluble, alpha 2
chrX_-_75578188 1.181 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr1_+_89454769 1.176 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr5_-_103211251 1.165 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr19_+_55253369 1.149 ENSMUST00000043150.4
Acsl5
acyl-CoA synthetase long-chain family member 5
chr17_+_34305883 1.148 ENSMUST00000074557.8
H2-Eb1
histocompatibility 2, class II antigen E beta
chr7_-_126566364 1.131 ENSMUST00000032992.5
Eif3c
eukaryotic translation initiation factor 3, subunit C
chr4_-_103215147 1.104 ENSMUST00000150285.1
Slc35d1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr2_-_165852149 1.057 ENSMUST00000109258.3
Zmynd8
zinc finger, MYND-type containing 8
chr2_+_10372426 1.024 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2


Scm-like with four mbt domains 2


chr10_+_11281583 1.018 ENSMUST00000070300.4
Fbxo30
F-box protein 30
chr2_-_152831665 1.016 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chrX_+_9885622 1.006 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr19_-_58455903 0.980 ENSMUST00000131877.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr6_-_142386974 0.971 ENSMUST00000129694.1
Recql
RecQ protein-like
chr12_-_99393010 0.938 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr6_-_142387035 0.919 ENSMUST00000032370.6
ENSMUST00000100832.3
ENSMUST00000128082.1
ENSMUST00000111803.2
Recql



RecQ protein-like



chr3_+_106113229 0.917 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr10_+_11281304 0.905 ENSMUST00000129456.1
Fbxo30
F-box protein 30
chr11_-_3266377 0.891 ENSMUST00000020741.5
Drg1
developmentally regulated GTP binding protein 1
chr4_+_33209259 0.886 ENSMUST00000108159.1
Srsf12
serine/arginine-rich splicing factor 12
chr7_+_83755904 0.855 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr9_+_22454290 0.835 ENSMUST00000168332.1
Gm17545
predicted gene, 17545
chr8_-_47713920 0.830 ENSMUST00000038738.5
Cdkn2aip
CDKN2A interacting protein
chr5_-_24581879 0.828 ENSMUST00000088299.4
Gm10221
predicted gene 10221
chrX_-_56598069 0.811 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr4_+_63544747 0.805 ENSMUST00000035301.6
Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr11_-_97996171 0.800 ENSMUST00000042971.9
Arl5c
ADP-ribosylation factor-like 5C
chr8_-_22653406 0.771 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr7_-_133123770 0.759 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chr4_-_141790891 0.749 ENSMUST00000038014.4
ENSMUST00000153880.1
Dnajc16

DnaJ (Hsp40) homolog, subfamily C, member 16

chr4_+_155522462 0.742 ENSMUST00000177094.1
Gnb1
guanine nucleotide binding protein (G protein), beta 1
chr10_+_127849917 0.715 ENSMUST00000077530.2
Rdh19
retinol dehydrogenase 19
chr16_+_17208135 0.711 ENSMUST00000169803.1
Rimbp3
RIMS binding protein 3
chr10_-_5069044 0.701 ENSMUST00000095899.3
Syne1
spectrin repeat containing, nuclear envelope 1
chr2_-_32424005 0.643 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr12_-_51971289 0.640 ENSMUST00000040583.5
Heatr5a
HEAT repeat containing 5A
chr3_-_106167564 0.629 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr11_+_74770822 0.625 ENSMUST00000141755.1
ENSMUST00000010698.6
Mettl16

methyltransferase like 16

chr11_-_110168073 0.620 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr4_-_44710408 0.614 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
Pax5









paired box gene 5









chr6_-_13871459 0.610 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr6_-_13871477 0.606 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr16_-_23890805 0.605 ENSMUST00000004480.3
Sst
somatostatin
chr13_+_23934434 0.570 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr12_-_56536895 0.552 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr8_-_54529951 0.544 ENSMUST00000067476.8
Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr18_-_66022580 0.517 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr4_-_143299498 0.501 ENSMUST00000030317.7
Pdpn
podoplanin
chr11_-_96075581 0.458 ENSMUST00000107686.1
ENSMUST00000107684.1
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr10_-_13193096 0.447 ENSMUST00000019950.4
Ltv1
LTV1 homolog (S. cerevisiae)
chr10_+_128267997 0.431 ENSMUST00000050901.2
Apof
apolipoprotein F
chr3_-_28765364 0.426 ENSMUST00000094335.3
Gm6505
predicted pseudogene 6505
chr10_-_81230773 0.424 ENSMUST00000047408.4
Atcay
ataxia, cerebellar, Cayman type homolog (human)
chr12_+_98628126 0.418 ENSMUST00000048402.5
ENSMUST00000101144.3
ENSMUST00000101146.3
Spata7


spermatogenesis associated 7


chr13_-_92483996 0.393 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B
chr13_-_23934156 0.389 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr14_-_41008256 0.381 ENSMUST00000136661.1
Fam213a
family with sequence similarity 213, member A
chr5_-_87490869 0.346 ENSMUST00000147854.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr9_+_109931458 0.310 ENSMUST00000072772.5
ENSMUST00000035055.8
Map4

microtubule-associated protein 4

chr12_-_65073927 0.309 ENSMUST00000021332.8
Fkbp3
FK506 binding protein 3
chr4_+_143413002 0.307 ENSMUST00000155157.1
Pramef8
PRAME family member 8
chr6_-_71823805 0.290 ENSMUST00000065103.2
Mrpl35
mitochondrial ribosomal protein L35
chr14_-_24486994 0.281 ENSMUST00000026322.7
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chrX_+_7909542 0.265 ENSMUST00000086274.2
Gm10490
predicted gene 10490
chr2_-_30048827 0.254 ENSMUST00000113711.2
Wdr34
WD repeat domain 34
chr3_+_76075583 0.252 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr2_+_107290590 0.250 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr3_-_95357156 0.250 ENSMUST00000107171.3
ENSMUST00000015841.5
ENSMUST00000107170.2
Setdb1


SET domain, bifurcated 1


chr16_-_46155077 0.243 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr6_-_122340525 0.242 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr7_+_88278085 0.240 ENSMUST00000032779.5
ENSMUST00000128791.1
Ctsc

cathepsin C

chr11_+_94044194 0.231 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr13_+_43370710 0.226 ENSMUST00000066804.4
Sirt5
sirtuin 5
chr7_-_103741322 0.224 ENSMUST00000051346.2
Olfr629
olfactory receptor 629
chrX_-_103623704 0.205 ENSMUST00000130063.1
ENSMUST00000125419.1
Ftx

Ftx transcript, Xist regulator (non-protein coding)

chr11_+_94044241 0.195 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr7_-_28949670 0.195 ENSMUST00000148196.1
Actn4
actinin alpha 4
chr7_+_19382005 0.187 ENSMUST00000062831.9
ENSMUST00000108461.1
ENSMUST00000108460.1
Ercc2


excision repair cross-complementing rodent repair deficiency, complementation group 2


chr19_-_7019423 0.184 ENSMUST00000040772.8
Fermt3
fermitin family homolog 3 (Drosophila)
chr12_-_80760541 0.153 ENSMUST00000073251.6
Ccdc177
coiled-coil domain containing 177
chr5_+_145140362 0.153 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr8_-_41417042 0.139 ENSMUST00000033999.6
Frg1
FSHD region gene 1
chr11_+_94044111 0.132 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr18_-_65939048 0.125 ENSMUST00000025396.3
Rax
retina and anterior neural fold homeobox
chr7_-_133123409 0.118 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr7_-_30626145 0.116 ENSMUST00000075738.4
Cox6b1
cytochrome c oxidase, subunit VIb polypeptide 1
chr9_-_71163224 0.109 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr15_+_36174010 0.109 ENSMUST00000180159.1
ENSMUST00000057177.6
Polr2k

polymerase (RNA) II (DNA directed) polypeptide K

chr17_-_86145139 0.094 ENSMUST00000095187.3
Srbd1
S1 RNA binding domain 1
chr6_+_31574967 0.093 ENSMUST00000150540.1
Gm6117
predicted gene 6117
chr18_-_20682963 0.086 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr6_-_122340499 0.080 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr5_+_31526989 0.055 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
Slc4a1ap


solute carrier family 4 (anion exchanger), member 1, adaptor protein


chr16_-_35490873 0.051 ENSMUST00000023550.7
Pdia5
protein disulfide isomerase associated 5
chr1_+_75142775 0.044 ENSMUST00000097694.4
Fam134a
family with sequence similarity 134, member A
chr4_+_143412920 0.034 ENSMUST00000132915.1
ENSMUST00000037356.7
Pramef8

PRAME family member 8

chr12_+_3365108 0.023 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr10_-_88605017 0.006 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0061055 myotome development(GO:0061055)
1.1 3.2 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.0 6.3 GO:0009405 pathogenesis(GO:0009405)
0.8 4.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.7 3.3 GO:0060467 negative regulation of fertilization(GO:0060467)
0.6 2.9 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 3.9 GO:0071420 cellular response to histamine(GO:0071420)
0.4 3.6 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.4 2.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 1.9 GO:0000733 DNA strand renaturation(GO:0000733)
0.3 3.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 0.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.3 1.0 GO:0046898 response to cycloheximide(GO:0046898)
0.2 16.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 1.2 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.2 1.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 1.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 2.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.7 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.4 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.7 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 4.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.5 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 1.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 0.8 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.6 GO:0014823 response to activity(GO:0014823)
0.0 3.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 1.6 GO:0042551 neuron maturation(GO:0042551)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 3.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.6 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 3.9 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.8 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 3.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 4.1 GO:0031045 dense core granule(GO:0031045)
0.2 0.8 GO:0001652 granular component(GO:0001652)
0.2 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 7.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 3.0 GO:0032590 dendrite membrane(GO:0032590)
0.1 2.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:0034448 EGO complex(GO:0034448)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.9 GO:0097470 ribbon synapse(GO:0097470)
0.0 5.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 2.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 1.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.3 1.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 2.3 GO:0005523 tropomyosin binding(GO:0005523)
0.2 3.2 GO:0001618 virus receptor activity(GO:0001618)
0.2 6.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 3.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 0.6 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.2 0.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 4.1 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 3.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 1.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.8 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 2.2 GO:0043274 phospholipase binding(GO:0043274)
0.1 5.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 1.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.2 GO:0001848 complement binding(GO:0001848)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.6 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.6 GO:0015250 water channel activity(GO:0015250)
0.1 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.4 GO:0016209 antioxidant activity(GO:0016209)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 17.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 5.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 1.4 GO:0002020 protease binding(GO:0002020)
0.0 4.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.6 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.4 6.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 3.9 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.2 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.1 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 6.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.4 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 2.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.5 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.0 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 4.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 3.9 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 1.4 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.2 1.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 3.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.8 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 3.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.2 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.8 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 5.4 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.2 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.5 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis