Motif ID: Foxo6

Z-value: 0.422


Transcription factors associated with Foxo6:

Gene SymbolEntrez IDGene Name
Foxo6 ENSMUSG00000052135.8 Foxo6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo6mm10_v2_chr4_-_120287349_120287349-0.142.3e-01Click!


Activity profile for motif Foxo6.

activity profile for motif Foxo6


Sorted Z-values histogram for motif Foxo6

Sorted Z-values for motif Foxo6



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxo6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 82 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_75111684 3.309 ENSMUST00000100542.3
 Ly6c2
lymphocyte antigen 6 complex, locus C2
chrY_-_6681243 2.055 ENSMUST00000115940.1
 Gm21719
predicted gene, 21719
chr1_-_184883218 2.025 ENSMUST00000048308.5
 C130074G19Rik
RIKEN cDNA C130074G19 gene
chr11_-_12027958 2.001 ENSMUST00000109654.1
 Grb10
growth factor receptor bound protein 10
chr10_-_93310963 1.909 ENSMUST00000151153.1
 Elk3
ELK3, member of ETS oncogene family
chr6_-_23248264 1.681 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_-_84425258 1.664 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chr16_+_10812915 1.592 ENSMUST00000115822.1
 Gm11172
predicted gene 11172
chr10_-_93311073 1.520 ENSMUST00000008542.5
 Elk3
ELK3, member of ETS oncogene family
chr4_+_134510999 1.454 ENSMUST00000105866.2
 Aunip
aurora kinase A and ninein interacting protein
chr1_-_162898665 1.432 ENSMUST00000111510.1
ENSMUST00000045902.6
 Fmo2

flavin containing monooxygenase 2

chr12_-_113260217 1.370 ENSMUST00000178282.1
 Igha
immunoglobulin heavy constant alpha
chr1_+_74391479 1.316 ENSMUST00000027367.7
 Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr3_-_106167564 1.298 ENSMUST00000063062.8
 Chi3l3
chitinase 3-like 3
chr2_-_67194695 1.206 ENSMUST00000147939.1
 Gm13598
predicted gene 13598
chr15_+_3270767 1.183 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chrX_-_163761323 1.173 ENSMUST00000059320.2
 Rnf138rt1
ring finger protein 138, retrogene 1
chr14_-_47418407 0.892 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr6_+_88724667 0.885 ENSMUST00000163271.1
 Mgll
monoglyceride lipase
chr9_+_25089422 0.781 ENSMUST00000086238.2
 Gm10181
predicted gene 10181

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.4 1.7 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.3 1.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 1.4 GO:0002385 mucosal immune response(GO:0002385)
0.0 1.3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.7 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.2 0.6 GO:0045004 DNA replication proofreading(GO:0045004)
0.2 0.6 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 0.6 GO:0097421 liver regeneration(GO:0097421)
0.0 0.6 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.5 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.9 GO:0043196 varicosity(GO:0043196)
0.0 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.5 GO:0097444 spine apparatus(GO:0097444)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 3.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 1.7 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 1.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.2 GO:0019843 rRNA binding(GO:0019843)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 0.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 PID_IGF1_PATHWAY IGF1 pathway
0.0 1.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.2 PID_IL23_PATHWAY IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.7 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.4 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.2 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.9 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.5 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions