Motif ID: Foxp1_Foxj2

Z-value: 1.183

Transcription factors associated with Foxp1_Foxj2:

Gene SymbolEntrez IDGene Name
Foxj2 ENSMUSG00000003154.9 Foxj2
Foxp1 ENSMUSG00000030067.11 Foxp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxp1mm10_v2_chr6_-_99266494_992665400.771.9e-16Click!
Foxj2mm10_v2_chr6_+_122819888_1228199380.544.3e-07Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp1_Foxj2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_22439719 28.612 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr6_-_148444336 24.895 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr8_-_84773381 17.955 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr8_+_36457548 17.872 ENSMUST00000135373.1
ENSMUST00000147525.1
6430573F11Rik

RIKEN cDNA 6430573F11 gene

chr16_-_22439570 16.676 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr15_-_60824942 15.757 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr3_+_68584154 14.884 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr15_-_66969616 14.627 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr4_-_15149755 14.185 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr6_-_58907120 14.060 ENSMUST00000059539.3
Nap1l5
nucleosome assembly protein 1-like 5
chr15_+_3270767 13.051 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr13_+_16014457 12.350 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr8_+_66386292 12.312 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr16_-_43979050 11.922 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr18_+_51117754 11.162 ENSMUST00000116639.2
Prr16
proline rich 16
chr10_+_60106452 11.141 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr4_-_14621805 10.900 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr18_+_36952621 10.804 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr2_-_64975762 10.539 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr19_+_26750939 10.521 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_155734800 10.331 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr9_-_102354685 9.984 ENSMUST00000035129.7
ENSMUST00000085169.5
Ephb1

Eph receptor B1

chr17_+_70561739 9.875 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr7_+_82175156 9.726 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr6_+_17491216 9.574 ENSMUST00000080469.5
Met
met proto-oncogene
chr15_-_101850778 9.071 ENSMUST00000023790.3
Krt1
keratin 1
chr7_+_16310412 8.615 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr11_-_54860564 8.588 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr13_+_118714678 8.572 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr9_-_121495678 8.515 ENSMUST00000035120.4
Cck
cholecystokinin
chr10_+_123264076 8.433 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr18_+_36939178 8.138 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr1_-_87573825 8.000 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr2_+_136713444 7.996 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr1_+_66386968 7.910 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr14_-_121698417 7.761 ENSMUST00000040700.7
Dock9
dedicator of cytokinesis 9
chr19_+_6400523 7.708 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr14_-_93888732 7.652 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr17_+_70522083 7.564 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr7_+_19176416 7.562 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr3_+_63295815 7.360 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chr16_-_4880284 7.329 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr16_-_92400067 7.301 ENSMUST00000023672.8
Rcan1
regulator of calcineurin 1
chr11_-_107348130 7.252 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr6_-_99028251 7.237 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
Foxp1



forkhead box P1



chr10_+_116177351 6.986 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr16_+_91269759 6.977 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr4_-_151108244 6.966 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr2_+_68117713 6.929 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_+_19658055 6.863 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr19_-_57118981 6.809 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
Ablim1


actin-binding LIM protein 1


chr17_+_70522149 6.722 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr12_-_11436607 6.696 ENSMUST00000072299.5
Vsnl1
visinin-like 1
chr7_+_16309577 6.673 ENSMUST00000002152.6
Bbc3
BCL2 binding component 3
chr15_+_92597104 6.608 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr3_-_145649970 6.606 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr8_-_46294592 6.528 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr7_+_110772604 6.496 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr17_+_55445375 6.347 ENSMUST00000133899.1
ENSMUST00000086878.3
St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr17_+_68837062 6.267 ENSMUST00000178545.1
Tmem200c
transmembrane protein 200C
chr15_+_21111452 6.228 ENSMUST00000075132.6
Cdh12
cadherin 12
chr16_-_23988852 6.204 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr9_-_112187766 6.203 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr4_+_101507947 6.112 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_33209259 6.071 ENSMUST00000108159.1
Srsf12
serine/arginine-rich splicing factor 12
chr2_-_6722187 5.964 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr9_-_40455670 5.889 ENSMUST00000165104.1
ENSMUST00000045682.5
Gramd1b

GRAM domain containing 1B

chr16_-_34263179 5.846 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr15_+_92161343 5.845 ENSMUST00000068378.5
Cntn1
contactin 1
chr18_+_37447641 5.802 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr15_+_25940846 5.757 ENSMUST00000110438.1
Fam134b
family with sequence similarity 134, member B
chr8_+_20136455 5.757 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811

predicted gene, 21811

chr1_-_72536930 5.741 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr4_+_85205120 5.739 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr4_-_14621669 5.732 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr9_-_77347816 5.687 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr3_-_146770218 5.678 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr4_+_101507855 5.673 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_-_99028874 5.601 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr7_-_19166119 5.473 ENSMUST00000094790.3
Gipr
gastric inhibitory polypeptide receptor
chr10_+_21882184 5.413 ENSMUST00000120509.1
Sgk1
serum/glucocorticoid regulated kinase 1
chr19_+_38264761 5.373 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr14_+_5517172 5.280 ENSMUST00000178220.1
Gm3488
predicted gene, 3488
chr14_+_5164535 5.280 ENSMUST00000179659.1
Gm3317
predicted gene 3317
chr2_+_32095518 5.247 ENSMUST00000057423.5
Ppapdc3
phosphatidic acid phosphatase type 2 domain containing 3
chr14_+_48120841 5.246 ENSMUST00000073150.4
Peli2
pellino 2
chr6_-_25690729 5.244 ENSMUST00000054867.6
Gpr37
G protein-coupled receptor 37
chr11_-_107470699 5.238 ENSMUST00000103064.3
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr6_-_99096196 5.219 ENSMUST00000175886.1
Foxp1
forkhead box P1
chr10_+_79716588 5.173 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr14_+_3667518 5.156 ENSMUST00000112801.3
Gm3020
predicted gene 3020
chr18_-_89769479 5.116 ENSMUST00000097495.3
Dok6
docking protein 6
chr2_-_57114970 5.056 ENSMUST00000028166.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr3_+_53488677 5.028 ENSMUST00000029307.3
Stoml3
stomatin (Epb7.2)-like 3
chr11_+_32286946 5.019 ENSMUST00000101387.3
Hbq1b
hemoglobin, theta 1B
chr11_-_101226414 5.008 ENSMUST00000100417.2
ENSMUST00000107285.1
ENSMUST00000107284.1
Ezh1


enhancer of zeste homolog 1 (Drosophila)


chr8_+_25911670 4.925 ENSMUST00000120653.1
ENSMUST00000126226.1
Kcnu1

potassium channel, subfamily U, member 1

chr2_-_45110336 4.892 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr2_-_7395879 4.885 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr8_+_19682268 4.872 ENSMUST00000153710.1
ENSMUST00000127799.1
Gm6483

predicted gene 6483

chr3_-_31310349 4.867 ENSMUST00000091259.2
Slc7a14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr18_-_61536522 4.809 ENSMUST00000171629.1
Arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr5_+_75152274 4.798 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr13_-_93499803 4.789 ENSMUST00000065537.7
Jmy
junction-mediating and regulatory protein
chr1_+_34005872 4.777 ENSMUST00000182296.1
Dst
dystonin
chr3_+_136670076 4.770 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr3_-_8964037 4.727 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr2_+_28641227 4.713 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
Tsc1


tuberous sclerosis 1


chr3_+_129532386 4.691 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr2_-_73892530 4.688 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
Atf2



activating transcription factor 2



chr3_+_68468162 4.683 ENSMUST00000182532.1
Schip1
schwannomin interacting protein 1
chr14_-_70630149 4.681 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr4_+_13751297 4.677 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_-_93519499 4.651 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr13_+_5861489 4.650 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr11_+_69095217 4.627 ENSMUST00000101004.2
Per1
period circadian clock 1
chrX_+_56786527 4.624 ENSMUST00000144600.1
Fhl1
four and a half LIM domains 1
chr4_+_43383449 4.599 ENSMUST00000135216.1
ENSMUST00000152322.1
Rusc2

RUN and SH3 domain containing 2

chr9_-_112187898 4.596 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr14_-_7473073 4.577 ENSMUST00000167833.2
Gm3752
predicted gene 3752
chr9_+_87015537 4.573 ENSMUST00000058846.4
Ripply2
ripply2 homolog (zebrafish)
chr5_+_150259922 4.548 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr18_-_34624562 4.529 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8



bromodomain containing 8



chr14_+_3348089 4.497 ENSMUST00000178722.1
Gm2956
predicted gene 2956
chr9_-_77347787 4.484 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr6_-_59024470 4.418 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr14_+_4126066 4.406 ENSMUST00000167397.2
Gm8108
predicted gene 8108
chr3_-_144202300 4.372 ENSMUST00000121796.1
ENSMUST00000121112.1
Lmo4

LIM domain only 4

chr7_-_140082489 4.334 ENSMUST00000026541.7
Caly
calcyon neuron-specific vesicular protein
chr6_-_99435345 4.332 ENSMUST00000113322.2
ENSMUST00000176850.1
ENSMUST00000176632.1
Foxp1


forkhead box P1


chr4_+_102570065 4.325 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_+_30541582 4.322 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr11_+_98741871 4.322 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr18_+_61105561 4.286 ENSMUST00000025523.6
Csf1r
colony stimulating factor 1 receptor
chr19_-_28911879 4.276 ENSMUST00000179171.1
AC163993.1
AC163993.1
chr14_+_4871156 4.263 ENSMUST00000166410.2
Gm3264
predicted gene 3264
chr13_-_102958084 4.227 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr14_-_7159273 4.203 ENSMUST00000090663.6
Gm3512
predicted gene 3512
chr18_-_36515798 4.183 ENSMUST00000025363.5
Hbegf
heparin-binding EGF-like growth factor
chr4_+_32238950 4.180 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr7_+_120843551 4.153 ENSMUST00000106489.1
ENSMUST00000143279.1
Eef2k

eukaryotic elongation factor-2 kinase

chr14_+_3428103 4.150 ENSMUST00000178060.1
Gm3005
predicted gene 3005
chr7_+_3303503 4.122 ENSMUST00000100301.4
Prkcg
protein kinase C, gamma
chr3_-_146781351 4.115 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr2_-_73892619 4.109 ENSMUST00000112007.1
ENSMUST00000112016.2
Atf2

activating transcription factor 2

chr14_+_4741737 4.101 ENSMUST00000178748.1
Gm3252
predicted gene 3252
chr2_-_73892588 4.092 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
Atf2


activating transcription factor 2


chr14_-_6874257 4.086 ENSMUST00000178298.1
ENSMUST00000179374.1
Gm3667
Gm3629
predicted gene 3667
predicted gene 3629
chr3_+_31902666 4.077 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr11_+_118433826 4.061 ENSMUST00000106286.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr13_-_67484225 4.058 ENSMUST00000019572.7
Zfp874b
zinc finger protein 874b
chr14_+_4198185 4.053 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr14_-_55116935 4.052 ENSMUST00000022819.5
Jph4
junctophilin 4
chr16_-_34262945 4.042 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr17_+_24886643 4.023 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr19_+_26623419 4.017 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_+_104178797 4.010 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chr14_+_4430992 4.002 ENSMUST00000164603.1
ENSMUST00000166848.1
Gm3173

predicted gene 3173

chr14_-_6411578 3.990 ENSMUST00000179312.1
Gm3591
predicted gene 3591
chr2_+_55437100 3.976 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr17_+_71204647 3.965 ENSMUST00000126681.1
Lpin2
lipin 2
chr12_-_85270564 3.948 ENSMUST00000019378.6
ENSMUST00000166821.1
Mlh3

mutL homolog 3 (E coli)

chr14_+_3825596 3.939 ENSMUST00000178256.1
Gm3002
predicted gene 3002
chr10_-_26373956 3.930 ENSMUST00000105519.3
ENSMUST00000040219.6
L3mbtl3

l(3)mbt-like 3 (Drosophila)

chr14_-_6266620 3.905 ENSMUST00000096172.5
Gm3411
predicted gene 3411
chr11_-_121388186 3.879 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr15_+_6422240 3.878 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr7_-_4844665 3.860 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr2_-_58052832 3.834 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr18_-_60648290 3.834 ENSMUST00000143275.2
Synpo
synaptopodin
chr7_-_12422751 3.798 ENSMUST00000080348.5
Zfp551
zinc fingr protein 551
chr5_+_5573952 3.796 ENSMUST00000101627.2
Gm8773
predicted gene 8773
chr8_+_25849618 3.786 ENSMUST00000098858.3
Kcnu1
potassium channel, subfamily U, member 1
chr18_+_37504264 3.778 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr7_-_12422488 3.769 ENSMUST00000120220.1
Zfp551
zinc fingr protein 551
chr6_+_8520008 3.747 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1

glucocorticoid induced transcript 1

chr6_-_83831736 3.738 ENSMUST00000058383.8
Paip2b
poly(A) binding protein interacting protein 2B
chr14_+_4514758 3.720 ENSMUST00000112776.2
Gm3173
predicted gene 3173
chr17_-_46890405 3.718 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr7_+_73391160 3.694 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr2_-_6721890 3.665 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr1_-_126830632 3.653 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr3_-_141931523 3.646 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr6_-_59024340 3.631 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr7_+_113207465 3.623 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr14_-_19569553 3.599 ENSMUST00000112595.2
Gm2237
predicted gene 2237
chr14_+_4665094 3.588 ENSMUST00000169675.2
Gm3239
predicted gene 3239
chr15_+_99392882 3.584 ENSMUST00000023749.8
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr12_-_71136611 3.577 ENSMUST00000021486.8
ENSMUST00000166120.1
Timm9

translocase of inner mitochondrial membrane 9

chr14_+_61607455 3.576 ENSMUST00000051184.8
Kcnrg
potassium channel regulator
chr11_-_110168073 3.568 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr4_-_42856771 3.542 ENSMUST00000107981.1
Gm12394
predicted gene 12394
chr11_+_75348433 3.538 ENSMUST00000044530.2
Smyd4
SET and MYND domain containing 4
chr3_+_101377074 3.515 ENSMUST00000043983.5
Igsf3
immunoglobulin superfamily, member 3
chr14_-_5863663 3.493 ENSMUST00000178594.1
Gm8237
predicted gene 8237
chr11_+_78499087 3.477 ENSMUST00000017488.4
Vtn
vitronectin
chr6_+_135362931 3.473 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr18_+_37518341 3.470 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr1_-_179546261 3.458 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr1_-_193370225 3.424 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 47.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
4.3 12.9 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
3.8 15.3 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
3.8 11.3 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
3.6 10.9 GO:0043379 memory T cell differentiation(GO:0043379)
3.5 10.5 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
2.7 18.7 GO:0019532 oxalate transport(GO:0019532)
2.5 12.3 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
2.5 7.4 GO:0071492 cellular response to UV-A(GO:0071492)
2.2 22.4 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
2.1 27.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.9 24.2 GO:0070842 aggresome assembly(GO:0070842)
1.8 14.5 GO:0060137 maternal process involved in parturition(GO:0060137)
1.7 7.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.7 24.4 GO:0001553 luteinization(GO:0001553)
1.7 8.7 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.7 6.9 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.7 5.0 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
1.7 18.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
1.7 10.0 GO:0014719 skeletal muscle satellite cell activation(GO:0014719) optic nerve morphogenesis(GO:0021631)
1.6 11.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.6 14.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
1.6 4.8 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
1.6 4.7 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
1.6 4.7 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
1.5 6.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.5 8.7 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
1.4 4.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.4 4.2 GO:0051542 elastin biosynthetic process(GO:0051542)
1.4 9.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.3 8.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
1.3 8.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.3 14.5 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
1.3 9.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
1.3 5.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
1.3 10.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.3 2.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.3 3.8 GO:0098886 modification of dendritic spine(GO:0098886)
1.3 5.1 GO:0051866 general adaptation syndrome(GO:0051866)
1.2 11.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.2 4.8 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
1.2 9.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
1.1 6.7 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
1.1 3.3 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
1.1 3.3 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.1 9.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.1 7.6 GO:0010968 regulation of microtubule nucleation(GO:0010968)
1.1 3.2 GO:0015886 heme transport(GO:0015886)
1.0 2.0 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.0 2.9 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.9 0.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.9 6.5 GO:0032264 IMP salvage(GO:0032264)
0.9 6.5 GO:0033227 dsRNA transport(GO:0033227)
0.9 2.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.9 9.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.9 8.0 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.9 4.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.9 2.6 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.9 9.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.9 2.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.9 2.6 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.8 3.4 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.8 3.4 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.8 4.1 GO:0032423 regulation of mismatch repair(GO:0032423)
0.8 8.5 GO:0097421 liver regeneration(GO:0097421)
0.8 6.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7 2.2 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.7 14.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.7 2.2 GO:0002159 desmosome assembly(GO:0002159)
0.7 2.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.7 2.2 GO:0009597 detection of virus(GO:0009597)
0.7 6.4 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.7 2.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.7 4.8 GO:0090527 actin filament reorganization(GO:0090527)
0.7 2.7 GO:0050904 diapedesis(GO:0050904)
0.7 2.7 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.7 3.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.7 2.0 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.7 2.0 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.7 3.9 GO:0007144 female meiosis I(GO:0007144)
0.7 5.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.7 2.6 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.6 1.9 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.6 1.3 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.6 1.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 3.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.6 9.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.6 1.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.6 2.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.6 12.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.6 2.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.6 0.6 GO:0014842 skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.6 8.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.6 2.9 GO:0008355 olfactory learning(GO:0008355)
0.6 1.7 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.6 16.6 GO:0018345 protein palmitoylation(GO:0018345)
0.6 2.2 GO:0016240 autophagosome docking(GO:0016240)
0.6 1.7 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.6 2.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.6 9.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 1.6 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.5 2.2 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.5 5.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.5 2.1 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.5 1.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 0.5 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.5 4.1 GO:0005513 detection of calcium ion(GO:0005513)
0.5 3.0 GO:0071476 cellular hypotonic response(GO:0071476)
0.5 1.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.5 6.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.5 3.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.5 13.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.5 19.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.5 2.8 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.5 3.7 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.4 2.2 GO:0060613 fat pad development(GO:0060613)
0.4 3.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.4 3.9 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.4 3.0 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4 4.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 2.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.4 4.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.4 0.4 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.4 2.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 2.0 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.4 1.2 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.4 6.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 9.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 10.0 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.4 1.9 GO:0090494 positive regulation of sphingolipid biosynthetic process(GO:0090154) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494) positive regulation of ceramide biosynthetic process(GO:2000304)
0.4 5.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.4 3.8 GO:0043589 skin morphogenesis(GO:0043589)
0.4 2.7 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.4 0.4 GO:0002086 diaphragm contraction(GO:0002086)
0.4 1.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.4 2.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.4 1.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.4 3.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 2.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.3 1.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.3 4.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 1.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 0.9 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.3 4.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.3 3.7 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.3 2.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 2.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.3 1.8 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.3 0.9 GO:0006553 lysine metabolic process(GO:0006553)
0.3 1.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.3 4.5 GO:0051639 actin filament network formation(GO:0051639)
0.3 2.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 5.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 0.9 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 6.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 1.5 GO:0019346 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.3 1.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.3 1.5 GO:0048539 bone marrow development(GO:0048539)
0.3 1.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.3 2.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 2.0 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.3 4.2 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.3 2.2 GO:0035608 protein deglutamylation(GO:0035608)
0.3 3.1 GO:0021766 hippocampus development(GO:0021766)
0.3 1.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.3 1.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 1.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3 0.8 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.3 2.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 1.9 GO:0042126 nitrate metabolic process(GO:0042126)
0.3 3.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 1.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.3 9.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.3 1.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.3 1.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.3 1.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 0.8 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.3 0.8 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.3 2.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 2.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 3.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 2.0 GO:0042118 endothelial cell activation(GO:0042118)
0.2 10.8 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.0 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.2 4.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.2 3.0 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 3.4 GO:0031280 negative regulation of cyclase activity(GO:0031280)
0.2 1.8 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 5.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 0.4 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 2.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.7 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 0.8 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 1.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.6 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 1.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 3.3 GO:0060973 cell migration involved in heart development(GO:0060973)
0.2 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.2 1.2 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.2 0.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 0.6 GO:0019230 proprioception(GO:0019230)
0.2 4.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 2.7 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 3.8 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 0.8 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.2 2.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 2.0 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.2 1.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 2.9 GO:0045475 locomotor rhythm(GO:0045475)
0.2 1.1 GO:0001927 exocyst assembly(GO:0001927)
0.2 6.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 2.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 3.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 2.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 4.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 0.9 GO:0017085 response to insecticide(GO:0017085)
0.2 2.1 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.2 1.6 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.2 2.0 GO:0007625 grooming behavior(GO:0007625)
0.2 21.0 GO:0007416 synapse assembly(GO:0007416)
0.2 0.8 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.2 1.0 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 2.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.2 0.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.6 GO:0010226 response to lithium ion(GO:0010226)
0.2 1.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 2.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 3.8 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 0.6 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.2 3.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 5.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 4.2 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.1 0.9 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 2.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 2.6 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.0 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 1.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.8 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 2.1 GO:0002021 response to dietary excess(GO:0002021)
0.1 2.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 2.5 GO:0007035 vacuolar acidification(GO:0007035)
0.1 1.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 2.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.7 GO:0045922 negative regulation of fatty acid biosynthetic process(GO:0045717) negative regulation of fatty acid metabolic process(GO:0045922)
0.1 2.7 GO:0019835 cytolysis(GO:0019835)
0.1 9.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 5.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 2.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 1.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 3.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.5 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 1.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 1.8 GO:0045581 negative regulation of T cell differentiation(GO:0045581)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.5 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 1.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 2.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.6 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 1.7 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.1 1.1 GO:0030953 astral microtubule organization(GO:0030953)
0.1 2.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 1.1 GO:0043153 photoperiodism(GO:0009648) entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.4 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.1 2.7 GO:0002931 response to ischemia(GO:0002931)
0.1 2.7 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.2 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.1 0.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 3.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 1.3 GO:0032060 bleb assembly(GO:0032060)
0.1 0.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.6 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 10.7 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.1 1.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 1.1 GO:0008209 androgen metabolic process(GO:0008209)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.8 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.1 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 5.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.7 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.6 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 1.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.9 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 1.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.0 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.6 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 1.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.3 GO:0060666 axonogenesis involved in innervation(GO:0060385) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 10.1 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.1 0.6 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.4 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1 1.4 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.1 0.7 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 1.6 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 0.2 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.2 GO:1902524 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.3 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.1 1.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.7 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.3 GO:0015817 histidine transport(GO:0015817)
0.1 0.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.7 GO:0045471 response to ethanol(GO:0045471)
0.1 0.1 GO:0032275 luteinizing hormone secretion(GO:0032275)
0.1 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.2 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 1.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.4 GO:0015879 carnitine transport(GO:0015879)
0.1 2.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.9 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.1 0.7 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.9 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.9 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.5 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.1 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.0 0.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 1.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.6 GO:0001881 receptor recycling(GO:0001881)
0.0 0.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0035412 regulation of catenin import into nucleus(GO:0035412) negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0042117 monocyte activation(GO:0042117)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.6 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.8 GO:0006826 iron ion transport(GO:0006826)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.4 GO:0001510 RNA methylation(GO:0001510)
0.0 1.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.9 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.0 2.2 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.0 0.7 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 1.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.0 0.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 2.0 GO:0050770 regulation of axonogenesis(GO:0050770)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.5 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 2.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.9 GO:0071806 intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
0.0 0.4 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 1.1 GO:0007030 Golgi organization(GO:0007030)
0.0 0.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.0 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.0 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 0.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0072384 organelle transport along microtubule(GO:0072384)
0.0 0.1 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 7.0 GO:0006396 RNA processing(GO:0006396)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0043512 inhibin A complex(GO:0043512)
2.0 8.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.8 9.1 GO:0001533 cornified envelope(GO:0001533)
1.8 8.8 GO:0097444 spine apparatus(GO:0097444)
1.7 5.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.7 5.2 GO:0098855 HCN channel complex(GO:0098855)
1.6 4.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.6 6.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.5 6.2 GO:0031673 H zone(GO:0031673)
1.2 4.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.9 4.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.9 7.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.8 4.1 GO:0030314 junctional membrane complex(GO:0030314)
0.8 4.8 GO:0005955 calcineurin complex(GO:0005955)
0.8 9.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 14.0 GO:0071564 npBAF complex(GO:0071564)
0.7 2.1 GO:0014802 terminal cisterna(GO:0014802)
0.7 3.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.7 2.6 GO:0071797 LUBAC complex(GO:0071797)
0.7 3.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.6 10.0 GO:0032433 filopodium tip(GO:0032433)
0.6 8.5 GO:0043203 axon hillock(GO:0043203)
0.6 2.4 GO:0044307 dendritic branch(GO:0044307)
0.6 1.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.6 2.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.5 6.0 GO:0070852 cell body fiber(GO:0070852)
0.5 2.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.5 15.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.5 3.8 GO:0033269 internode region of axon(GO:0033269)
0.5 5.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 14.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 3.6 GO:0033391 chromatoid body(GO:0033391)
0.4 2.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.4 3.9 GO:0032300 mismatch repair complex(GO:0032300)
0.4 1.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.4 2.8 GO:0005874 microtubule(GO:0005874)
0.4 2.2 GO:0035976 AP1 complex(GO:0035976)
0.4 2.2 GO:0044327 dendritic spine head(GO:0044327)
0.4 3.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 9.8 GO:0031430 M band(GO:0031430)
0.3 2.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 1.4 GO:0071437 invadopodium(GO:0071437)
0.3 2.0 GO:0061689 tricellular tight junction(GO:0061689)
0.3 3.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 4.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 4.6 GO:0032281 ionotropic glutamate receptor complex(GO:0008328) AMPA glutamate receptor complex(GO:0032281) neurotransmitter receptor complex(GO:0098878)
0.3 1.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 1.2 GO:0044305 calyx of Held(GO:0044305)
0.3 3.2 GO:0000812 Swr1 complex(GO:0000812)
0.3 2.6 GO:0002177 manchette(GO:0002177)
0.3 2.5 GO:0071565 nBAF complex(GO:0071565)
0.3 2.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 1.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 3.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.3 3.4 GO:0031672 A band(GO:0031672)
0.3 3.2 GO:0030057 desmosome(GO:0030057)
0.2 13.7 GO:0009925 basal plasma membrane(GO:0009925)
0.2 2.9 GO:0051286 cell tip(GO:0051286)
0.2 21.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 1.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 4.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 0.7 GO:0044194 cytolytic granule(GO:0044194)
0.2 8.7 GO:0044291 cell-cell contact zone(GO:0044291)
0.2 8.3 GO:0035861 site of double-strand break(GO:0035861)
0.2 1.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 1.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 5.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 0.8 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 8.1 GO:0031252 cell leading edge(GO:0031252)
0.2 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 1.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 3.9 GO:0030667 secretory granule membrane(GO:0030667)
0.2 1.5 GO:0001520 outer dense fiber(GO:0001520)
0.2 0.8 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 1.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 0.2 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.2 2.6 GO:0031143 pseudopodium(GO:0031143)
0.2 2.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 2.0 GO:0032590 dendrite membrane(GO:0032590)
0.2 3.4 GO:0005605 basal lamina(GO:0005605)
0.2 3.4 GO:0005921 gap junction(GO:0005921)
0.2 1.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 2.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 2.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 1.9 GO:0030673 axolemma(GO:0030673)
0.2 7.3 GO:0031941 filamentous actin(GO:0031941)
0.2 1.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 0.8 GO:0043219 lateral loop(GO:0043219)
0.2 6.2 GO:0031201 SNARE complex(GO:0031201)
0.2 1.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 2.2 GO:0031514 motile cilium(GO:0031514)
0.1 50.7 GO:0097060 synaptic membrane(GO:0097060)
0.1 1.6 GO:0032426 stereocilium tip(GO:0032426)
0.1 2.2 GO:0042555 MCM complex(GO:0042555)
0.1 1.9 GO:0043679 axon terminus(GO:0043679)
0.1 11.9 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 11.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 7.4 GO:0005769 early endosome(GO:0005769)
0.1 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 1.4 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 7.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 2.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.4 GO:0005869 dynactin complex(GO:0005869)
0.1 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.0 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.1 1.3 GO:0046930 pore complex(GO:0046930)
0.1 0.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 1.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 4.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 3.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.2 GO:0042588 zymogen granule(GO:0042588)
0.1 2.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 12.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 8.7 GO:0016605 PML body(GO:0016605)
0.1 10.3 GO:0005903 brush border(GO:0005903)
0.1 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 3.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.1 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 19.8 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.6 GO:0012505 endomembrane system(GO:0012505)
0.1 3.8 GO:0005795 Golgi stack(GO:0005795)
0.1 1.5 GO:0000145 exocyst(GO:0000145)
0.1 1.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 2.2 GO:0030018 Z disc(GO:0030018)
0.1 5.4 GO:0030139 endocytic vesicle(GO:0030139)
0.1 9.3 GO:0005770 late endosome(GO:0005770)
0.1 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.7 GO:0042641 actomyosin(GO:0042641)
0.1 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 12.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.8 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.7 GO:0038201 TOR complex(GO:0038201)
0.1 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 3.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0000243 commitment complex(GO:0000243)
0.1 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 17.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 0.2 GO:0031209 SCAR complex(GO:0031209)
0.1 26.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.6 GO:0043204 perikaryon(GO:0043204)
0.0 5.4 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 2.2 GO:0000502 proteasome complex(GO:0000502)
0.0 1.0 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.8 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 14.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 5.7 GO:0045202 synapse(GO:0045202)
0.0 4.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 6.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 1.7 GO:0005657 replication fork(GO:0005657)
0.0 1.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 5.2 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 2.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 6.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0045177 apical part of cell(GO:0045177)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 6.0 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 28.6 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 11.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
3.0 17.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
2.9 8.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
2.4 9.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
2.1 12.3 GO:0070699 type II activin receptor binding(GO:0070699)
1.7 6.9 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.7 18.7 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
1.7 10.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.6 6.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.4 8.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.4 4.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.4 4.2 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
1.4 4.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
1.3 4.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
1.3 5.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.2 13.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
1.2 7.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.1 12.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.1 1.1 GO:0050897 cobalt ion binding(GO:0050897)
1.1 3.2 GO:0015232 heme transporter activity(GO:0015232)
1.1 8.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.1 5.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.0 8.2 GO:0032051 clathrin light chain binding(GO:0032051)
1.0 7.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.0 3.9 GO:0019237 centromeric DNA binding(GO:0019237)
1.0 4.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.9 6.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.9 2.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.9 2.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.9 3.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.8 4.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.8 7.1 GO:0034046 poly(G) binding(GO:0034046)
0.8 3.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.8 6.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.7 2.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.7 4.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.7 2.0 GO:0009881 photoreceptor activity(GO:0009881)
0.7 2.0 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.6 7.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.6 15.1 GO:0042287 MHC protein binding(GO:0042287)
0.6 1.9 GO:0098809 nitrite reductase activity(GO:0098809)
0.6 2.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.6 2.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.6 2.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.6 16.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.6 4.7 GO:0005131 growth hormone receptor binding(GO:0005131)
0.6 4.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.6 1.7 GO:0071253 connexin binding(GO:0071253)
0.6 5.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.6 2.8 GO:0097643 amylin receptor activity(GO:0097643)
0.5 15.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 4.7 GO:0004630 phospholipase D activity(GO:0004630)
0.5 3.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.5 2.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.5 1.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.5 2.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 2.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.5 3.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.5 9.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.5 2.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5 2.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 2.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4 2.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 3.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4 1.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 2.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4 3.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 2.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 4.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 2.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 5.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.4 3.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 17.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 4.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 2.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 4.4 GO:0005243 gap junction channel activity(GO:0005243)
0.4 4.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.4 3.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.4 1.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.4 21.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.4 5.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 6.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 1.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 6.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.4 7.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 4.7 GO:0043621 protein self-association(GO:0043621)
0.3 1.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 4.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.3 1.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 1.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.5 GO:0045499 chemorepellent activity(GO:0045499)
0.3 0.6 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.3 3.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 2.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 9.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 2.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.3 5.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.3 0.8 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.3 1.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 10.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 0.8 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.3 9.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3 0.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 2.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.3 13.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 2.5 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 2.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 1.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 2.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 26.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 2.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 5.1 GO:0017046 peptide hormone binding(GO:0017046)
0.2 1.0 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 2.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.4 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.2 0.6 GO:0019966 C-X-C chemokine binding(GO:0019958) interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120)
0.2 6.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 6.9 GO:0005112 Notch binding(GO:0005112)
0.2 2.3 GO:0030957 Tat protein binding(GO:0030957)
0.2 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.0 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.2 4.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.3 GO:0019213 deacetylase activity(GO:0019213)
0.2 10.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 1.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 1.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 0.5 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 0.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 1.6 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.2 2.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 2.4 GO:0030955 potassium ion binding(GO:0030955)
0.2 1.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 9.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 1.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 1.0 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2 0.5 GO:0019002 GMP binding(GO:0019002)
0.2 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.8 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 0.8 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.2 0.8 GO:0031014 troponin T binding(GO:0031014)
0.2 2.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 3.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 1.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.7 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 4.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 1.3 GO:0043495 protein anchor(GO:0043495)
0.1 0.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.0 GO:0030911 TPR domain binding(GO:0030911)
0.1 2.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 3.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 6.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 5.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.6 GO:0008199 ferroxidase activity(GO:0004322) ferric iron binding(GO:0008199) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 19.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.6 GO:0048038 quinone binding(GO:0048038)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 1.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.0 GO:0001846 opsonin binding(GO:0001846)
0.1 3.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 4.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 7.7 GO:0051117 ATPase binding(GO:0051117)
0.1 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.7 GO:0051018 protein kinase A binding(GO:0051018)
0.1 2.1 GO:0031489 myosin V binding(GO:0031489)
0.1 1.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.4 GO:0005537 mannose binding(GO:0005537)
0.1 14.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 11.7 GO:0044325 ion channel binding(GO:0044325)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.6 GO:0035381 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381)
0.1 0.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.6 GO:0030553 cGMP binding(GO:0030553)
0.1 0.8 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.2 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.1 2.5 GO:0070888 E-box binding(GO:0070888)
0.1 2.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.9 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 4.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 2.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 3.6 GO:0019003 GDP binding(GO:0019003)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.3 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.1 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.1 GO:0005518 collagen binding(GO:0005518)
0.1 1.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.2 GO:0004096 catalase activity(GO:0004096)
0.1 1.4 GO:0045503 dynein light chain binding(GO:0045503)
0.1 2.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.5 GO:0050681 androgen receptor binding(GO:0050681)
0.1 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.1 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 2.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 19.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 1.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 2.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 6.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.6 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.5 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 3.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)
0.0 0.4 GO:0005507 copper ion binding(GO:0005507)
0.0 6.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 8.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.0 GO:0035091 phosphatidylinositol binding(GO:0035091)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 48.3 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
1.3 5.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.6 10.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5 2.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.5 9.0 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.5 14.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.4 2.6 PID_FOXO_PATHWAY FoxO family signaling
0.4 3.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 19.5 PID_RHOA_PATHWAY RhoA signaling pathway
0.4 2.3 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.4 4.8 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.4 13.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.3 11.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.3 8.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.3 7.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.3 5.5 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.3 2.6 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.3 13.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.3 4.1 PID_ENDOTHELIN_PATHWAY Endothelins
0.3 11.4 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.3 5.7 PID_IL2_1PATHWAY IL2-mediated signaling events
0.3 4.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.3 5.0 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.3 21.4 PID_LKB1_PATHWAY LKB1 signaling events
0.2 3.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.2 8.9 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.2 13.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.2 5.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 6.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.2 6.1 ST_ADRENERGIC Adrenergic Pathway
0.2 0.6 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.2 2.2 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.2 6.3 PID_SHP2_PATHWAY SHP2 signaling
0.2 3.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 4.2 PID_ALK1_PATHWAY ALK1 signaling events
0.2 0.7 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.9 ST_GA12_PATHWAY G alpha 12 Pathway
0.2 10.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.2 1.4 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.2 3.8 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 4.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.1 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 3.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 3.3 PID_FGF_PATHWAY FGF signaling pathway
0.1 1.7 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 4.0 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 1.8 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 0.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.1 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 2.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.4 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 2.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 0.9 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 1.9 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 0.6 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.1 9.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 1.2 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.3 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 3.2 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.4 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 2.2 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 3.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.6 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
1.1 11.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.0 2.0 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
1.0 2.0 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
1.0 1.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
1.0 12.4 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.9 2.7 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.9 15.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.6 14.7 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.6 8.0 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.6 20.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.5 11.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.5 6.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.5 4.2 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.5 2.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.4 5.2 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.4 6.8 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.4 6.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.4 10.7 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.4 3.4 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 4.4 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.3 3.1 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.3 4.0 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.3 11.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.3 8.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.3 11.7 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 4.9 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 4.2 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 2.8 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 5.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.3 3.0 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.3 7.5 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.3 3.3 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.2 1.7 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 3.1 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 5.1 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 0.6 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 4.7 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.2 6.3 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.2 4.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 1.8 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 1.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 4.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 8.7 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 2.7 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 4.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 4.7 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 2.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 3.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 1.9 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 5.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.1 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.7 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 2.2 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 1.6 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.9 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 11.8 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 1.1 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 1.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 2.5 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 1.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 4.5 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.1 3.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.1 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.1 0.9 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 1.4 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 4.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 4.2 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.1 0.8 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 0.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 1.4 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.2 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.1 1.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.1 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 1.1 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.6 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 0.7 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.1 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.9 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.8 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.8 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.8 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.4 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 4.4 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism