Motif ID: Foxp1_Foxj2
Z-value: 1.183
Transcription factors associated with Foxp1_Foxj2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxj2 | ENSMUSG00000003154.9 | Foxj2 |
| Foxp1 | ENSMUSG00000030067.11 | Foxp1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxp1 | mm10_v2_chr6_-_99266494_99266540 | 0.77 | 1.9e-16 | Click! |
| Foxj2 | mm10_v2_chr6_+_122819888_122819938 | 0.54 | 4.3e-07 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 407 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.4 | 47.2 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 2.1 | 27.2 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 1.7 | 24.4 | GO:0001553 | luteinization(GO:0001553) |
| 1.9 | 24.2 | GO:0070842 | aggresome assembly(GO:0070842) |
| 2.2 | 22.4 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
| 0.2 | 21.0 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.5 | 19.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 2.7 | 18.7 | GO:0019532 | oxalate transport(GO:0019532) |
| 1.7 | 18.3 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.6 | 16.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 3.8 | 15.3 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 1.8 | 14.5 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 1.6 | 14.5 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 1.3 | 14.5 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.7 | 14.1 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.5 | 13.5 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 4.3 | 12.9 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 0.6 | 12.5 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 2.5 | 12.3 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
| 1.6 | 11.4 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 211 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 50.7 | GO:0097060 | synaptic membrane(GO:0097060) |
| 0.0 | 28.6 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.1 | 26.6 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.2 | 21.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 19.8 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 17.3 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.5 | 15.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.5 | 14.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 14.2 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.7 | 14.0 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 13.7 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 12.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 12.5 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 4.1 | 12.3 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.1 | 11.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 11.3 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 10.3 | GO:0005903 | brush border(GO:0005903) |
| 0.6 | 10.0 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.8 | 9.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.3 | 9.8 | GO:0031430 | M band(GO:0031430) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 277 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 26.2 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.4 | 21.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 19.9 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 19.0 | GO:0005509 | calcium ion binding(GO:0005509) |
| 1.7 | 18.7 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 3.0 | 17.7 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.4 | 17.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.6 | 16.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.5 | 15.7 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.6 | 15.1 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 14.5 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 1.2 | 13.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.3 | 13.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 1.1 | 12.5 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 2.1 | 12.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 3.0 | 11.9 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.1 | 11.7 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.3 | 10.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.2 | 10.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 1.7 | 10.0 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 71 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 48.3 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.3 | 21.4 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.4 | 19.5 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.5 | 14.2 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.4 | 13.9 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.3 | 13.5 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.2 | 13.3 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.3 | 11.7 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.3 | 11.4 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.2 | 10.8 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.6 | 10.1 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 9.9 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.5 | 9.0 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.2 | 8.9 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
| 0.3 | 8.0 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.3 | 7.5 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.2 | 6.6 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.2 | 6.3 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.2 | 6.1 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.3 | 5.7 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 119 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 20.6 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.9 | 15.5 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.6 | 14.7 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 1.0 | 12.4 | REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 3.1 | 12.3 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 11.8 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.3 | 11.7 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 1.1 | 11.3 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.5 | 11.3 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.3 | 11.2 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.4 | 10.7 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.2 | 8.7 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.3 | 8.4 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.6 | 8.0 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.3 | 7.5 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.4 | 6.8 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
| 0.4 | 6.5 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.2 | 6.3 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.5 | 6.2 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.2 | 5.5 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
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