Motif ID: Fubp1

Z-value: 0.718


Transcription factors associated with Fubp1:

Gene SymbolEntrez IDGene Name
Fubp1 ENSMUSG00000028034.9 Fubp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fubp1mm10_v2_chr3_+_152210458_152210534-0.104.0e-01Click!


Activity profile for motif Fubp1.

activity profile for motif Fubp1


Sorted Z-values histogram for motif Fubp1

Sorted Z-values for motif Fubp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Fubp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 129 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_112187766 7.837 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr7_-_110862944 7.451 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr9_-_112187898 7.015 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr11_+_44617310 6.338 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr2_-_32353283 5.358 ENSMUST00000091089.5
ENSMUST00000113350.1
 Dnm1

dynamin 1

chr2_-_32353247 5.208 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
 Dnm1


dynamin 1


chr18_+_86711520 4.655 ENSMUST00000122464.1
 Cbln2
cerebellin 2 precursor protein
chr12_+_109545390 4.263 ENSMUST00000146701.1
 Meg3
maternally expressed 3
chr18_+_86711059 3.951 ENSMUST00000068423.3
 Cbln2
cerebellin 2 precursor protein
chr5_-_44799643 3.809 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chrX_-_106485214 3.175 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr10_-_33624587 2.833 ENSMUST00000160299.1
ENSMUST00000019920.6
 Clvs2

clavesin 2

chr2_+_103970115 2.556 ENSMUST00000111143.1
ENSMUST00000138815.1
 Lmo2

LIM domain only 2

chr2_+_103970221 2.464 ENSMUST00000111140.2
ENSMUST00000111139.2
 Lmo2

LIM domain only 2

chr2_+_103969528 2.391 ENSMUST00000123437.1
ENSMUST00000163256.1
 Lmo2

LIM domain only 2

chr18_+_35770318 2.226 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr5_-_5266038 2.220 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
 Cdk14


cyclin-dependent kinase 14


chr2_-_28916412 2.132 ENSMUST00000050776.2
ENSMUST00000113849.1
 Barhl1

BarH-like 1 (Drosophila)

chr10_+_50895651 2.111 ENSMUST00000020071.3
 Sim1
single-minded homolog 1 (Drosophila)
chr11_-_106715251 2.052 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
 Pecam1



platelet/endothelial cell adhesion molecule 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 14.9 GO:0034605 cellular response to heat(GO:0034605)
1.5 10.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 8.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.7 7.5 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.6 7.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 4.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 3.8 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 3.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 2.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 2.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 2.2 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.5 2.1 GO:0050904 diapedesis(GO:0050904)
0.0 2.1 GO:0030901 midbrain development(GO:0030901)
0.4 1.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.6 1.7 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.5 1.6 GO:0015747 urate transport(GO:0015747)
0.5 1.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 1.6 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.3 GO:0005667 transcription factor complex(GO:0005667)
0.7 10.6 GO:0043196 varicosity(GO:0043196)
0.2 3.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 2.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 2.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4 2.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 1.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 1.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.5 1.4 GO:0018444 translation release factor complex(GO:0018444)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 1.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.2 0.9 GO:0032585 multivesicular body membrane(GO:0032585)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 13.3 GO:0005516 calmodulin binding(GO:0005516)
1.1 10.6 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.4 7.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 7.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.5 6.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 4.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 3.8 GO:0030274 LIM domain binding(GO:0030274)
0.3 3.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 2.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.1 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 1.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 1.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.5 1.6 GO:0004875 complement receptor activity(GO:0004875)
0.4 1.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 1.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.6 GO:0008276 protein methyltransferase activity(GO:0008276)
0.2 1.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.3 10.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.7 PID_ALK1_PATHWAY ALK1 signaling events
0.0 2.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.6 PID_BMP_PATHWAY BMP receptor signaling
0.1 1.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID_MYC_PATHWAY C-MYC pathway
0.0 0.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 10.6 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 8.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.7 7.0 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 2.7 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 2.7 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 2.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 1.6 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.3 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 1.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.1 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.1 0.8 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.7 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.7 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis