Motif ID: Gata5

Z-value: 0.806


Transcription factors associated with Gata5:

Gene SymbolEntrez IDGene Name
Gata5 ENSMUSG00000015627.5 Gata5



Activity profile for motif Gata5.

activity profile for motif Gata5


Sorted Z-values histogram for motif Gata5

Sorted Z-values for motif Gata5



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 138 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 11.178 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr16_-_50432340 6.598 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
 Bbx




bobby sox homolog (Drosophila)




chr8_+_45658666 6.386 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
 Sorbs2


sorbin and SH3 domain containing 2


chr8_+_45658273 6.330 ENSMUST00000153798.1
 Sorbs2
sorbin and SH3 domain containing 2
chr14_+_75455957 6.245 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr11_+_32276893 5.423 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276400 5.236 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr13_+_108316332 5.038 ENSMUST00000051594.5
 Depdc1b
DEP domain containing 1B
chr11_+_95337012 4.959 ENSMUST00000037502.6
 Fam117a
family with sequence similarity 117, member A
chr12_-_27342696 4.082 ENSMUST00000079063.5
 Sox11
SRY-box containing gene 11
chr16_-_50330987 4.015 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr16_-_44558879 3.954 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr13_+_108316395 3.826 ENSMUST00000171178.1
 Depdc1b
DEP domain containing 1B
chr5_+_93093428 3.517 ENSMUST00000074733.7
 Sept11
septin 11
chr11_-_101551837 3.405 ENSMUST00000017290.4
 Brca1
breast cancer 1
chr7_-_70366735 3.368 ENSMUST00000089565.5
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr12_+_95692212 2.865 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr13_-_62520451 2.685 ENSMUST00000082203.6
ENSMUST00000101547.4
 Zfp934

zinc finger protein 934

chr2_+_71786923 2.612 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr9_+_80165079 2.593 ENSMUST00000184480.1
 Myo6
myosin VI

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.4 21.8 GO:0015671 oxygen transport(GO:0015671)
0.3 15.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 8.9 GO:0060348 bone development(GO:0060348)
0.1 6.6 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
1.2 6.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
1.4 4.1 GO:0060023 soft palate development(GO:0060023)
0.2 4.0 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 3.5 GO:0051291 protein heterooligomerization(GO:0051291)
1.1 3.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.7 3.4 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 3.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.3 2.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.4 2.6 GO:0035878 nail development(GO:0035878)
0.2 2.6 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 2.2 GO:0090527 actin filament reorganization(GO:0090527)
0.2 2.2 GO:0006517 protein deglycosylation(GO:0006517)
0.1 2.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 2.2 GO:0007030 Golgi organization(GO:0007030)
0.7 2.1 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 2.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 17.0 GO:0005833 hemoglobin complex(GO:0005833)
0.0 13.9 GO:0014069 postsynaptic density(GO:0014069)
0.1 4.0 GO:0044295 axonal growth cone(GO:0044295)
0.6 3.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 3.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 2.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 2.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 2.5 GO:0036038 MKS complex(GO:0036038)
0.1 2.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0032993 protein-DNA complex(GO:0032993)
0.2 1.0 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.4 21.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 9.5 GO:0019904 protein domain specific binding(GO:0019904)
0.0 8.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 4.1 GO:0003774 motor activity(GO:0003774)
0.3 3.4 GO:0001972 retinoic acid binding(GO:0001972)
0.1 3.4 GO:0003684 damaged DNA binding(GO:0003684)
0.2 2.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.9 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.5 2.6 GO:0038132 neuregulin binding(GO:0038132)
0.2 2.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 2.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 2.0 GO:0052650 retinal binding(GO:0016918) NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 1.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.5 1.4 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 1.4 GO:0030553 cGMP binding(GO:0030553)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 3.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.3 2.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.4 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.4 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.2 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.1 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 3.4 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 3.4 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.6 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.2 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism