Motif ID: Gata6

Z-value: 0.322


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Showing 1 to 20 of 69 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 3.129 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_103853199 2.837 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr8_+_45628176 2.458 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627946 2.388 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627709 2.311 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr12_+_95692212 1.556 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr16_-_46010212 1.010 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr4_+_13751297 0.990 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_179803376 0.931 ENSMUST00000097454.2
Gm10518
predicted gene 10518
chr9_+_66350465 0.847 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr8_-_122699066 0.821 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr2_+_71786923 0.769 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr4_-_110287479 0.739 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr3_-_154330543 0.665 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr5_-_73191848 0.634 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr2_+_65930117 0.598 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr16_-_34262945 0.592 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr1_-_25829511 0.590 ENSMUST00000135518.1
ENSMUST00000151309.1
Bai3

brain-specific angiogenesis inhibitor 3

chr2_-_59948155 0.501 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr2_+_68104671 0.479 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.5 3.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 2.8 GO:0015671 oxygen transport(GO:0015671)
0.2 1.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.1 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.8 GO:0035878 nail development(GO:0035878)
0.1 0.8 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.7 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.6 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0000019 regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.5 GO:0014069 postsynaptic density(GO:0014069)
0.4 2.8 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.2 1.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:1990357 terminal web(GO:1990357)

Gene overrepresentation in molecular_function category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.8 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.3 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks