Motif ID: Gli1
Z-value: 0.803
Transcription factors associated with Gli1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Gli1 | ENSMUSG00000025407.6 | Gli1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Gli1 | mm10_v2_chr10_-_127341583_127341614 | -0.56 | 1.2e-07 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 6.8 | GO:0010751 | negative regulation of nitric oxide mediated signal transduction(GO:0010751) |
| 1.8 | 5.3 | GO:0016332 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) |
| 1.5 | 4.4 | GO:2000331 | regulation of terminal button organization(GO:2000331) |
| 1.5 | 4.4 | GO:0071336 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
| 1.4 | 6.9 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 1.1 | 4.3 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 1.1 | 4.2 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 1.0 | 15.6 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 0.9 | 10.3 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.9 | 2.6 | GO:2000850 | protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 0.8 | 7.6 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.8 | 4.5 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.7 | 5.4 | GO:0051798 | positive regulation of hair follicle development(GO:0051798) |
| 0.6 | 1.7 | GO:1904978 | regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
| 0.5 | 2.2 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.5 | 5.3 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.5 | 2.0 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.5 | 3.4 | GO:0098909 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.4 | 4.5 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.4 | 3.2 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.4 | 1.5 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.4 | 1.1 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 0.4 | 1.9 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.4 | 2.5 | GO:1990416 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.4 | 2.1 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.3 | 1.7 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) |
| 0.3 | 6.6 | GO:0042711 | maternal behavior(GO:0042711) |
| 0.3 | 1.3 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 0.3 | 3.8 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.3 | 1.3 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.2 | 1.4 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.2 | 0.7 | GO:0010838 | positive regulation of keratinocyte proliferation(GO:0010838) |
| 0.2 | 2.9 | GO:1901898 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.2 | 3.8 | GO:0001553 | luteinization(GO:0001553) |
| 0.2 | 1.0 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.2 | 3.0 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.2 | 0.6 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
| 0.2 | 3.1 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.2 | 2.5 | GO:0045019 | negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406) |
| 0.2 | 2.2 | GO:0031639 | plasminogen activation(GO:0031639) |
| 0.2 | 1.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.2 | 1.1 | GO:0032811 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811) |
| 0.2 | 0.9 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.1 | 1.4 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 0.1 | 1.5 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.1 | 0.6 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 0.5 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
| 0.1 | 0.6 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.1 | 2.8 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 0.7 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 0.4 | GO:1903028 | regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028) |
| 0.1 | 2.0 | GO:0042104 | positive regulation of activated T cell proliferation(GO:0042104) |
| 0.1 | 0.4 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.1 | 0.4 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) chromatin maintenance(GO:0070827) |
| 0.1 | 0.5 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.1 | 0.9 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.1 | 0.5 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.1 | 1.2 | GO:0007530 | sex determination(GO:0007530) |
| 0.1 | 3.6 | GO:0003407 | neural retina development(GO:0003407) |
| 0.0 | 2.1 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.2 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.0 | 1.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.2 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.0 | 2.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 4.8 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 2.4 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.1 | GO:0072014 | proximal tubule development(GO:0072014) |
| 0.0 | 5.5 | GO:0002757 | immune response-activating signal transduction(GO:0002757) |
| 0.0 | 0.4 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.4 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 1.6 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.0 | 0.2 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.0 | 0.6 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.0 | 0.1 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.0 | 0.5 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.2 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 0.0 | 0.2 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.0 | 0.7 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
| 0.0 | 2.4 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 5.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.8 | 2.4 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.6 | 4.2 | GO:0042825 | TAP complex(GO:0042825) |
| 0.5 | 7.6 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.5 | 1.4 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.4 | 1.9 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.3 | 9.0 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.2 | 1.1 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.2 | 2.5 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 2.1 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.1 | 0.6 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.1 | 0.4 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 1.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 1.4 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 0.6 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.1 | 6.9 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 0.9 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 9.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 6.9 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 2.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 1.7 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.1 | 1.3 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 8.7 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.1 | 2.8 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 14.4 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 2.6 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.8 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 2.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 1.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.2 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 3.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.0 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.2 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 7.7 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 4.4 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 1.6 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 3.6 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 1.4 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 2.2 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 2.1 | GO:0016324 | apical plasma membrane(GO:0016324) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 5.5 | GO:0070052 | collagen V binding(GO:0070052) |
| 1.3 | 5.3 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
| 1.1 | 4.4 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 1.1 | 4.2 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980) |
| 0.9 | 4.5 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.9 | 2.6 | GO:0009881 | photoreceptor activity(GO:0009881) |
| 0.8 | 2.4 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.8 | 6.9 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.7 | 2.1 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.6 | 4.3 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 0.6 | 2.2 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.5 | 1.6 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.5 | 2.2 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.5 | 5.4 | GO:0048185 | activin binding(GO:0048185) |
| 0.5 | 5.3 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.4 | 7.6 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.4 | 2.0 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.4 | 1.1 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.3 | 1.7 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.3 | 2.8 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 3.8 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.3 | 2.0 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.2 | 4.4 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 0.7 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.2 | 3.5 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.2 | 1.4 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.2 | 1.1 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.2 | 1.5 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.2 | 1.0 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.2 | 18.6 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.2 | 3.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.4 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.1 | 10.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 4.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 2.2 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.1 | 1.6 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.1 | 1.5 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.1 | 2.9 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 0.6 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.1 | 4.9 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 0.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.1 | 0.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 1.9 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 4.5 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 1.5 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 0.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 2.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.9 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.5 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.0 | 0.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.4 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.0 | 0.6 | GO:0001163 | RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.0 | 3.4 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 1.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 0.7 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 1.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.1 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.0 | 0.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.0 | 0.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.6 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 3.8 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.3 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.2 | 9.2 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.1 | 19.6 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 2.6 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.1 | 5.9 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 2.4 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 1.5 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 2.7 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.6 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 7.1 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 2.5 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
| 0.0 | 1.9 | PID_BCR_5PATHWAY | BCR signaling pathway |
| 0.0 | 1.7 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.0 | 1.5 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.4 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.0 | 1.0 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 5.3 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.5 | 6.9 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.5 | 7.6 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.4 | 4.4 | REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.3 | 4.2 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.3 | 9.0 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 4.2 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 2.8 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 2.0 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 1.5 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 2.2 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 2.3 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 2.9 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 3.8 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 0.9 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 5.5 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 6.4 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 5.1 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 2.5 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 2.6 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 1.9 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.7 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 1.7 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 1.1 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 2.5 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 1.0 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.9 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 0.4 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.0 | 0.6 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.4 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
