Motif ID: Gzf1

Z-value: 0.307


Transcription factors associated with Gzf1:

Gene SymbolEntrez IDGene Name
Gzf1 ENSMUSG00000027439.9 Gzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gzf1mm10_v2_chr2_+_148681199_148681218-0.421.5e-04Click!


Activity profile for motif Gzf1.

activity profile for motif Gzf1


Sorted Z-values histogram for motif Gzf1

Sorted Z-values for motif Gzf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gzf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_19751257 1.102 ENSMUST00000022340.3
 Nid2
nidogen 2
chr17_-_55915870 1.066 ENSMUST00000074828.4
 Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr4_-_134128707 1.002 ENSMUST00000105879.1
ENSMUST00000030651.8
 Sh3bgrl3

SH3 domain binding glutamic acid-rich protein-like 3

chr14_+_11227511 0.956 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr2_-_93996354 0.884 ENSMUST00000183110.1
 Gm27027
predicted gene, 27027
chr8_+_105855086 0.863 ENSMUST00000040445.7
 Thap11
THAP domain containing 11
chr4_+_129513581 0.709 ENSMUST00000062356.6
 Marcksl1
MARCKS-like 1
chr4_+_154960915 0.678 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr7_-_30612731 0.629 ENSMUST00000006476.4
 Upk1a
uroplakin 1A
chr8_-_78508876 0.607 ENSMUST00000049245.7
 Rbmxl1
RNA binding motif protein, X linked-like-1
chr9_-_116175318 0.564 ENSMUST00000061101.4
ENSMUST00000035014.6
 Tgfbr2

transforming growth factor, beta receptor II

chr6_-_52012476 0.461 ENSMUST00000078214.5
 Skap2
src family associated phosphoprotein 2
chr17_+_47594629 0.424 ENSMUST00000182846.1
 Ccnd3
cyclin D3
chr2_+_29827342 0.417 ENSMUST00000091142.3
 Urm1
ubiquitin related modifier 1 homolog (S. cerevisiae)
chr12_+_109540979 0.390 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
 Meg3


maternally expressed 3


chr4_-_129542710 0.390 ENSMUST00000102597.4
 Hdac1
histone deacetylase 1
chr16_+_65815508 0.328 ENSMUST00000168064.1
 Vgll3
vestigial like 3 (Drosophila)
chr8_+_78509319 0.307 ENSMUST00000034111.8
 Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr16_-_28445227 0.299 ENSMUST00000100024.1
 Fgf12
fibroblast growth factor 12
chr7_-_29168647 0.260 ENSMUST00000048923.6
 Spred3
sprouty-related, EVH1 domain containing 3
chr11_-_33163072 0.249 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
 Npm1



nucleophosmin 1



chr4_-_124862171 0.240 ENSMUST00000064444.7
 Maneal
mannosidase, endo-alpha-like
chr2_-_153632775 0.212 ENSMUST00000071852.3
 Commd7
COMM domain containing 7
chr14_+_55854115 0.076 ENSMUST00000168479.1
 Nynrin
NYN domain and retroviral integrase containing
chr13_+_37826225 0.020 ENSMUST00000128570.1
 Rreb1
ras responsive element binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003274 endocardial cushion fusion(GO:0003274)
0.2 0.7 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
0.1 0.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.4 GO:0061198 fungiform papilla formation(GO:0061198) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 1.0 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID_GLYPICAN_1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME_G1_PHASE Genes involved in G1 Phase