Motif ID: Hey1_Myc_Mxi1
Z-value: 0.982
Transcription factors associated with Hey1_Myc_Mxi1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hey1 | ENSMUSG00000040289.3 | Hey1 |
Mxi1 | ENSMUSG00000025025.7 | Mxi1 |
Myc | ENSMUSG00000022346.8 | Myc |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Mxi1 | mm10_v2_chr19_+_53329413_53329478 | -0.45 | 3.8e-05 | Click! |
Hey1 | mm10_v2_chr3_-_8667033_8667046 | -0.42 | 1.3e-04 | Click! |
Myc | mm10_v2_chr15_+_61987034_61987059 | 0.16 | 1.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.4 | 24.0 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
3.3 | 9.8 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
3.2 | 9.5 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
3.1 | 12.3 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
2.6 | 10.4 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
2.5 | 7.6 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
2.3 | 16.4 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
2.2 | 6.7 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
2.2 | 2.2 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
2.2 | 6.5 | GO:0046881 | positive regulation of follicle-stimulating hormone secretion(GO:0046881) |
2.2 | 10.8 | GO:0008355 | olfactory learning(GO:0008355) |
2.1 | 6.4 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
2.1 | 6.4 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
2.0 | 6.1 | GO:0043379 | memory T cell differentiation(GO:0043379) |
2.0 | 8.0 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
1.8 | 5.3 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
1.6 | 6.5 | GO:0097296 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296) |
1.6 | 8.1 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
1.6 | 4.8 | GO:0042823 | pyridoxal phosphate biosynthetic process(GO:0042823) |
1.6 | 4.8 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
1.5 | 7.7 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
1.5 | 4.6 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
1.5 | 4.5 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
1.5 | 4.4 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
1.4 | 8.6 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
1.4 | 2.8 | GO:0021586 | pons maturation(GO:0021586) |
1.4 | 4.1 | GO:0019405 | hexitol metabolic process(GO:0006059) alditol catabolic process(GO:0019405) |
1.4 | 6.8 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
1.3 | 3.9 | GO:1990523 | bone regeneration(GO:1990523) |
1.3 | 7.5 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
1.2 | 3.7 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
1.2 | 6.1 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
1.2 | 5.9 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
1.2 | 3.6 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
1.2 | 2.4 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
1.2 | 3.5 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
1.1 | 5.5 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
1.1 | 4.4 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
1.1 | 3.3 | GO:0072034 | renal vesicle induction(GO:0072034) |
1.1 | 11.7 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
1.0 | 3.1 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) |
1.0 | 1.0 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
0.9 | 2.8 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
0.9 | 4.6 | GO:0071692 | protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) |
0.9 | 2.7 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
0.9 | 4.5 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.9 | 2.7 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.9 | 7.1 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.9 | 25.9 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.8 | 3.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.8 | 2.4 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.8 | 4.7 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
0.8 | 8.5 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.8 | 0.8 | GO:1901536 | regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) |
0.7 | 2.2 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
0.7 | 3.7 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
0.7 | 5.0 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
0.7 | 2.8 | GO:0007412 | axon target recognition(GO:0007412) |
0.7 | 7.0 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.7 | 2.1 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.7 | 5.5 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
0.7 | 2.0 | GO:0090004 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
0.7 | 2.7 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
0.7 | 2.6 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
0.6 | 9.0 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
0.6 | 4.5 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.6 | 5.0 | GO:1901857 | positive regulation of cellular respiration(GO:1901857) |
0.6 | 2.5 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
0.6 | 3.7 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.6 | 1.9 | GO:0015886 | heme transport(GO:0015886) |
0.6 | 1.8 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
0.6 | 2.5 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.6 | 4.8 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
0.6 | 3.0 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
0.6 | 4.8 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
0.6 | 2.4 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.6 | 2.3 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.6 | 3.5 | GO:0035902 | response to immobilization stress(GO:0035902) |
0.6 | 2.9 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.6 | 1.7 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
0.6 | 4.0 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.6 | 2.8 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
0.5 | 14.6 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
0.5 | 2.7 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.5 | 4.8 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.5 | 8.6 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.5 | 2.1 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.5 | 3.7 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
0.5 | 1.0 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.5 | 4.2 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
0.5 | 2.6 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
0.5 | 3.5 | GO:0015862 | uridine transport(GO:0015862) |
0.5 | 1.5 | GO:0070625 | zymogen granule exocytosis(GO:0070625) |
0.5 | 3.5 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.5 | 0.5 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
0.5 | 2.4 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
0.5 | 2.4 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.5 | 1.9 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
0.5 | 1.4 | GO:0010512 | negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) |
0.5 | 0.5 | GO:0007567 | parturition(GO:0007567) |
0.5 | 2.3 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.5 | 1.4 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.5 | 2.3 | GO:0032423 | regulation of mismatch repair(GO:0032423) |
0.5 | 2.3 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.4 | 2.7 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
0.4 | 1.3 | GO:0045590 | negative regulation of regulatory T cell differentiation(GO:0045590) |
0.4 | 1.8 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
0.4 | 1.8 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
0.4 | 1.3 | GO:0051182 | coenzyme transport(GO:0051182) |
0.4 | 6.9 | GO:0031167 | rRNA methylation(GO:0031167) |
0.4 | 3.9 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
0.4 | 2.5 | GO:0051013 | microtubule severing(GO:0051013) |
0.4 | 3.6 | GO:0009644 | response to high light intensity(GO:0009644) |
0.4 | 3.2 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
0.4 | 1.2 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.4 | 1.2 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
0.4 | 2.0 | GO:0046113 | nucleobase catabolic process(GO:0046113) |
0.4 | 2.8 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.4 | 1.6 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
0.4 | 1.2 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) |
0.4 | 1.1 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.4 | 0.4 | GO:0001844 | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844) |
0.4 | 2.6 | GO:0019400 | glycerol metabolic process(GO:0006071) alditol metabolic process(GO:0019400) |
0.4 | 1.1 | GO:0090343 | positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774) |
0.4 | 2.6 | GO:0051004 | regulation of lipoprotein lipase activity(GO:0051004) |
0.4 | 1.5 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
0.4 | 8.1 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.4 | 4.7 | GO:0070842 | aggresome assembly(GO:0070842) |
0.4 | 1.1 | GO:0016240 | autophagosome docking(GO:0016240) |
0.4 | 2.1 | GO:0003383 | apical constriction(GO:0003383) |
0.4 | 1.4 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
0.3 | 1.0 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.3 | 0.7 | GO:0072179 | nephric duct formation(GO:0072179) |
0.3 | 1.7 | GO:1903609 | angiotensin-activated signaling pathway involved in heart process(GO:0086098) negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
0.3 | 2.7 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
0.3 | 0.3 | GO:0098712 | L-glutamate import across plasma membrane(GO:0098712) |
0.3 | 3.3 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.3 | 1.0 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.3 | 1.0 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.3 | 6.5 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
0.3 | 1.6 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
0.3 | 1.3 | GO:0021986 | epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866) |
0.3 | 1.3 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
0.3 | 0.6 | GO:1903294 | regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296) |
0.3 | 7.5 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
0.3 | 1.2 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
0.3 | 1.5 | GO:0015871 | choline transport(GO:0015871) |
0.3 | 4.5 | GO:1904874 | positive regulation of telomerase RNA localization to Cajal body(GO:1904874) |
0.3 | 1.2 | GO:0050812 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
0.3 | 0.9 | GO:0019659 | fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
0.3 | 3.0 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.3 | 0.6 | GO:0097477 | lateral motor column neuron migration(GO:0097477) |
0.3 | 0.9 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
0.3 | 1.5 | GO:0090292 | nuclear migration along microfilament(GO:0031022) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
0.3 | 5.1 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.3 | 1.1 | GO:0048703 | embryonic viscerocranium morphogenesis(GO:0048703) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
0.3 | 2.6 | GO:0071569 | protein ufmylation(GO:0071569) |
0.3 | 2.3 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
0.3 | 3.1 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.3 | 3.4 | GO:0097186 | amelogenesis(GO:0097186) |
0.3 | 7.3 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.3 | 1.7 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
0.3 | 3.3 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
0.3 | 3.3 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.3 | 1.9 | GO:0015879 | carnitine transport(GO:0015879) |
0.3 | 0.8 | GO:0030974 | thiamine pyrophosphate transport(GO:0030974) |
0.3 | 1.1 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
0.3 | 1.4 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
0.3 | 1.1 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.3 | 1.6 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
0.3 | 2.2 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
0.3 | 0.8 | GO:1903054 | protein targeting to vacuole involved in autophagy(GO:0071211) chaperone-mediated protein transport(GO:0072321) lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) |
0.3 | 1.1 | GO:0006244 | pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
0.3 | 2.4 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.3 | 1.6 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
0.3 | 0.8 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
0.3 | 1.6 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.3 | 0.3 | GO:0021593 | rhombomere morphogenesis(GO:0021593) |
0.3 | 0.8 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.3 | 0.5 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
0.3 | 7.3 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.2 | 6.5 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
0.2 | 0.2 | GO:0090035 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
0.2 | 1.2 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.2 | 4.2 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
0.2 | 1.0 | GO:0018201 | peptidyl-glycine modification(GO:0018201) |
0.2 | 0.5 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
0.2 | 4.4 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.2 | 2.7 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.2 | 0.7 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
0.2 | 2.4 | GO:0021960 | anterior commissure morphogenesis(GO:0021960) |
0.2 | 1.0 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
0.2 | 1.9 | GO:0002115 | store-operated calcium entry(GO:0002115) |
0.2 | 0.7 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
0.2 | 0.9 | GO:0007000 | nucleolus organization(GO:0007000) |
0.2 | 1.2 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
0.2 | 0.5 | GO:0001956 | positive regulation of neurotransmitter secretion(GO:0001956) |
0.2 | 1.2 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
0.2 | 0.7 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
0.2 | 0.5 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
0.2 | 0.7 | GO:0032763 | regulation of mast cell cytokine production(GO:0032763) |
0.2 | 1.4 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.2 | 1.6 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.2 | 0.7 | GO:0048820 | hair follicle maturation(GO:0048820) |
0.2 | 0.7 | GO:2000510 | positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.2 | 6.5 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
0.2 | 2.3 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.2 | 1.1 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
0.2 | 0.7 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.2 | 2.4 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
0.2 | 2.2 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.2 | 2.2 | GO:0003229 | ventricular cardiac muscle tissue development(GO:0003229) |
0.2 | 4.6 | GO:0046033 | AMP metabolic process(GO:0046033) |
0.2 | 6.5 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
0.2 | 0.7 | GO:0019046 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046) |
0.2 | 0.9 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.2 | 1.7 | GO:0014029 | neural crest formation(GO:0014029) |
0.2 | 4.5 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
0.2 | 0.6 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
0.2 | 1.3 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
0.2 | 0.6 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
0.2 | 3.2 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
0.2 | 1.1 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
0.2 | 0.8 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.2 | 14.0 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.2 | 1.7 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.2 | 0.2 | GO:1902548 | negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548) |
0.2 | 1.0 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
0.2 | 2.0 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.2 | 1.4 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
0.2 | 1.0 | GO:0046684 | response to insecticide(GO:0017085) response to pyrethroid(GO:0046684) |
0.2 | 1.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.2 | 1.0 | GO:0000393 | spliceosomal conformational changes to generate catalytic conformation(GO:0000393) |
0.2 | 2.4 | GO:0015816 | glycine transport(GO:0015816) |
0.2 | 0.4 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
0.2 | 1.5 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.2 | 0.9 | GO:0046950 | cellular ketone body metabolic process(GO:0046950) |
0.2 | 0.9 | GO:0046016 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016) |
0.2 | 1.1 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
0.2 | 1.9 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
0.2 | 0.9 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.2 | 1.9 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
0.2 | 1.3 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
0.2 | 1.5 | GO:0015791 | polyol transport(GO:0015791) |
0.2 | 1.7 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.2 | 0.7 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.2 | 0.6 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
0.2 | 0.7 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
0.2 | 2.4 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
0.2 | 4.9 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.2 | 0.9 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
0.2 | 0.9 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.2 | 0.2 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.2 | 1.8 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.2 | 1.8 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.2 | 1.3 | GO:0043084 | penile erection(GO:0043084) |
0.2 | 0.9 | GO:0032439 | endosome localization(GO:0032439) |
0.2 | 0.5 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055) |
0.2 | 0.5 | GO:0006449 | regulation of translational termination(GO:0006449) |
0.2 | 1.6 | GO:0018208 | peptidyl-proline modification(GO:0018208) |
0.2 | 0.5 | GO:0060468 | prevention of polyspermy(GO:0060468) |
0.2 | 2.4 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.2 | 2.1 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.2 | 1.0 | GO:0006560 | proline metabolic process(GO:0006560) |
0.2 | 1.2 | GO:0031424 | keratinization(GO:0031424) |
0.2 | 0.9 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
0.2 | 0.7 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
0.2 | 2.7 | GO:1990403 | embryonic brain development(GO:1990403) |
0.2 | 12.7 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
0.2 | 1.8 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.2 | 0.3 | GO:0009446 | putrescine biosynthetic process(GO:0009446) |
0.2 | 1.3 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.2 | 0.3 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.2 | 2.4 | GO:0030104 | water homeostasis(GO:0030104) |
0.2 | 4.8 | GO:0001706 | endoderm formation(GO:0001706) |
0.2 | 1.4 | GO:0048484 | enteric nervous system development(GO:0048484) |
0.2 | 2.5 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.2 | 0.9 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.2 | 2.8 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.2 | 0.5 | GO:0070459 | prolactin secretion(GO:0070459) |
0.2 | 0.5 | GO:0002014 | vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014) |
0.2 | 1.7 | GO:0042407 | cristae formation(GO:0042407) |
0.2 | 1.4 | GO:0043589 | anagen(GO:0042640) skin morphogenesis(GO:0043589) |
0.2 | 0.6 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.2 | 1.4 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.2 | 0.6 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.1 | 0.4 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
0.1 | 0.4 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.1 | 0.6 | GO:0098902 | regulation of membrane depolarization during action potential(GO:0098902) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825) |
0.1 | 1.3 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.1 | 1.4 | GO:0007141 | male meiosis I(GO:0007141) |
0.1 | 0.3 | GO:2000224 | regulation of testosterone biosynthetic process(GO:2000224) |
0.1 | 0.6 | GO:2000109 | macrophage apoptotic process(GO:0071888) protein sialylation(GO:1990743) regulation of macrophage apoptotic process(GO:2000109) negative regulation of macrophage apoptotic process(GO:2000110) |
0.1 | 3.9 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.1 | 0.6 | GO:0030576 | Cajal body organization(GO:0030576) |
0.1 | 0.4 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.1 | 0.4 | GO:0043686 | co-translational protein modification(GO:0043686) |
0.1 | 2.6 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.1 | 0.7 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.1 | 1.1 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.1 | 1.1 | GO:0034312 | diol biosynthetic process(GO:0034312) |
0.1 | 1.1 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
0.1 | 0.3 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
0.1 | 0.7 | GO:1905247 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247) |
0.1 | 0.3 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
0.1 | 0.9 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
0.1 | 1.1 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.1 | 2.1 | GO:0006308 | DNA catabolic process(GO:0006308) |
0.1 | 0.4 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
0.1 | 0.4 | GO:0034035 | sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
0.1 | 2.5 | GO:0002052 | positive regulation of neuroblast proliferation(GO:0002052) |
0.1 | 0.3 | GO:0048597 | post-embryonic camera-type eye morphogenesis(GO:0048597) |
0.1 | 0.4 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
0.1 | 0.5 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
0.1 | 0.2 | GO:2001160 | negative regulation of urine volume(GO:0035811) regulation of histone H3-K79 methylation(GO:2001160) |
0.1 | 0.4 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.1 | 0.7 | GO:0071880 | adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880) |
0.1 | 0.5 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.1 | 2.0 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.1 | 1.7 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
0.1 | 0.8 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.1 | 3.5 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.1 | 0.9 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
0.1 | 2.2 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.1 | 0.7 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.1 | 0.5 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
0.1 | 0.7 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) proton-transporting two-sector ATPase complex assembly(GO:0070071) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.1 | 0.6 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.1 | 1.1 | GO:0055012 | ventricular cardiac muscle cell differentiation(GO:0055012) |
0.1 | 0.3 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.1 | 1.0 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
0.1 | 2.2 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
0.1 | 5.4 | GO:0009311 | oligosaccharide metabolic process(GO:0009311) |
0.1 | 1.6 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
0.1 | 2.1 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.1 | 1.2 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
0.1 | 0.9 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.1 | 0.4 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
0.1 | 0.5 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.1 | 0.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.1 | 2.2 | GO:0050850 | positive regulation of calcium-mediated signaling(GO:0050850) |
0.1 | 0.6 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.1 | 7.0 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
0.1 | 3.6 | GO:0045471 | response to ethanol(GO:0045471) |
0.1 | 2.1 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.1 | 2.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.1 | 0.1 | GO:0043504 | mitochondrial DNA repair(GO:0043504) |
0.1 | 1.2 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.1 | 0.1 | GO:1900368 | regulation of RNA interference(GO:1900368) |
0.1 | 0.3 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.1 | 0.3 | GO:0002347 | response to tumor cell(GO:0002347) |
0.1 | 0.4 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
0.1 | 1.4 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.1 | 0.3 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
0.1 | 0.3 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
0.1 | 0.3 | GO:0042891 | antibiotic transport(GO:0042891) |
0.1 | 0.9 | GO:0018126 | protein hydroxylation(GO:0018126) |
0.1 | 0.4 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.1 | 1.1 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.1 | 0.2 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
0.1 | 1.1 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
0.1 | 0.5 | GO:0021554 | optic nerve development(GO:0021554) |
0.1 | 1.1 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.1 | 0.1 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
0.1 | 1.1 | GO:0070207 | protein homotrimerization(GO:0070207) |
0.1 | 0.4 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
0.1 | 2.0 | GO:1903146 | regulation of mitophagy(GO:1903146) |
0.1 | 2.0 | GO:0016079 | synaptic vesicle exocytosis(GO:0016079) |
0.1 | 1.1 | GO:0000338 | protein deneddylation(GO:0000338) |
0.1 | 0.4 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
0.1 | 1.1 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.1 | 2.6 | GO:0043406 | positive regulation of MAP kinase activity(GO:0043406) |
0.1 | 0.5 | GO:0000491 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492) |
0.1 | 2.4 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
0.1 | 1.2 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.1 | 0.4 | GO:0051601 | exocyst localization(GO:0051601) |
0.1 | 0.3 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.1 | 0.6 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.1 | 1.0 | GO:0040019 | positive regulation of embryonic development(GO:0040019) |
0.1 | 1.5 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.1 | 1.6 | GO:0030488 | tRNA methylation(GO:0030488) |
0.1 | 0.2 | GO:0018343 | protein farnesylation(GO:0018343) |
0.1 | 1.2 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.1 | 0.2 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
0.1 | 0.2 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
0.1 | 0.3 | GO:0014889 | muscle atrophy(GO:0014889) |
0.1 | 0.5 | GO:0044130 | negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146) |
0.1 | 0.3 | GO:0042220 | response to cocaine(GO:0042220) |
0.1 | 0.3 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.1 | 0.3 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.1 | 7.6 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
0.1 | 0.4 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.1 | 0.2 | GO:0034123 | positive regulation of toll-like receptor signaling pathway(GO:0034123) |
0.1 | 0.4 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
0.1 | 0.4 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
0.0 | 0.5 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 0.1 | GO:0023035 | CD40 signaling pathway(GO:0023035) |
0.0 | 0.2 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.0 | 0.9 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.0 | 0.3 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.0 | 0.2 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
0.0 | 0.2 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
0.0 | 0.2 | GO:0050909 | sensory perception of taste(GO:0050909) |
0.0 | 0.8 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 1.0 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 1.1 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.1 | GO:0046655 | folic acid metabolic process(GO:0046655) |
0.0 | 0.1 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate proteoglycan metabolic process(GO:0050655) |
0.0 | 0.3 | GO:0001773 | myeloid dendritic cell activation(GO:0001773) |
0.0 | 0.7 | GO:0071711 | basement membrane organization(GO:0071711) |
0.0 | 0.2 | GO:0006868 | glutamine transport(GO:0006868) |
0.0 | 1.5 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
0.0 | 0.2 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
0.0 | 0.6 | GO:0030203 | glycosaminoglycan metabolic process(GO:0030203) |
0.0 | 0.6 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 1.4 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.0 | 3.8 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
0.0 | 0.3 | GO:0009249 | protein lipoylation(GO:0009249) |
0.0 | 0.4 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 0.4 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.0 | 1.0 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
0.0 | 0.5 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
0.0 | 0.1 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
0.0 | 0.2 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
0.0 | 1.6 | GO:0042073 | intraciliary transport(GO:0042073) |
0.0 | 0.8 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
0.0 | 0.2 | GO:0051697 | protein delipidation(GO:0051697) |
0.0 | 0.2 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.0 | 0.0 | GO:0035247 | peptidyl-arginine N-methylation(GO:0035246) peptidyl-arginine omega-N-methylation(GO:0035247) |
0.0 | 1.0 | GO:0045214 | sarcomere organization(GO:0045214) |
0.0 | 0.7 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.0 | 1.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 1.7 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
0.0 | 0.4 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 1.8 | GO:0031398 | positive regulation of protein ubiquitination(GO:0031398) |
0.0 | 0.1 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
0.0 | 0.8 | GO:0006400 | tRNA modification(GO:0006400) |
0.0 | 0.4 | GO:0030317 | sperm motility(GO:0030317) |
0.0 | 0.1 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.0 | 0.6 | GO:0097178 | ruffle assembly(GO:0097178) |
0.0 | 0.1 | GO:0019062 | virion attachment to host cell(GO:0019062) transforming growth factor beta activation(GO:0036363) adhesion of symbiont to host cell(GO:0044650) complement-dependent cytotoxicity(GO:0097278) |
0.0 | 0.5 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.0 | 0.7 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 1.6 | GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway(GO:2001237) |
0.0 | 0.1 | GO:0051309 | female meiosis chromosome separation(GO:0051309) |
0.0 | 0.2 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.0 | 0.2 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
0.0 | 0.4 | GO:0046460 | triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463) |
0.0 | 0.5 | GO:0051341 | regulation of oxidoreductase activity(GO:0051341) |
0.0 | 0.1 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
0.0 | 0.8 | GO:0071466 | cellular response to xenobiotic stimulus(GO:0071466) |
0.0 | 0.2 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.6 | GO:0060291 | long-term synaptic potentiation(GO:0060291) |
0.0 | 0.1 | GO:1903432 | regulation of TORC1 signaling(GO:1903432) |
0.0 | 0.7 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.4 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
0.0 | 1.4 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
0.0 | 0.2 | GO:0002092 | positive regulation of receptor internalization(GO:0002092) |
0.0 | 0.3 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.0 | 0.2 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.3 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
0.0 | 0.1 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
0.0 | 0.2 | GO:0071549 | response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549) |
0.0 | 0.1 | GO:0060134 | prepulse inhibition(GO:0060134) |
0.0 | 0.0 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
0.0 | 0.2 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.0 | 0.6 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.0 | 0.1 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
0.0 | 0.3 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
0.0 | 0.2 | GO:0003338 | metanephros morphogenesis(GO:0003338) |
0.0 | 0.2 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.0 | 0.0 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
0.0 | 0.1 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.0 | 0.5 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 0.0 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.0 | 0.2 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.0 | 0.2 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 12.4 | GO:0044194 | cytolytic granule(GO:0044194) |
2.6 | 10.2 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
2.4 | 19.1 | GO:0097433 | dense body(GO:0097433) |
1.7 | 8.6 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
1.6 | 6.5 | GO:0043511 | inhibin complex(GO:0043511) |
1.5 | 7.6 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
1.2 | 6.1 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
1.2 | 4.9 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
1.2 | 2.4 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
1.0 | 16.3 | GO:0043196 | varicosity(GO:0043196) |
0.9 | 10.3 | GO:0005642 | annulate lamellae(GO:0005642) |
0.9 | 2.8 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.9 | 4.4 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.7 | 2.2 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
0.7 | 2.1 | GO:0005927 | muscle tendon junction(GO:0005927) |
0.7 | 13.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.7 | 2.8 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.7 | 6.7 | GO:0070545 | PeBoW complex(GO:0070545) |
0.7 | 9.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.6 | 3.2 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.6 | 3.7 | GO:0008091 | spectrin(GO:0008091) |
0.5 | 2.1 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.5 | 2.6 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.4 | 3.1 | GO:0033263 | CORVET complex(GO:0033263) |
0.4 | 3.1 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) |
0.4 | 3.5 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.4 | 4.8 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.4 | 1.2 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
0.4 | 0.8 | GO:0099524 | region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524) |
0.4 | 8.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.4 | 0.7 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.4 | 1.5 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.4 | 2.6 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.4 | 1.1 | GO:0000802 | transverse filament(GO:0000802) |
0.4 | 9.6 | GO:0030686 | 90S preribosome(GO:0030686) |
0.4 | 4.6 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.3 | 5.6 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.3 | 1.0 | GO:0044753 | amphisome(GO:0044753) |
0.3 | 0.7 | GO:0044432 | endoplasmic reticulum part(GO:0044432) |
0.3 | 2.0 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.3 | 7.4 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.3 | 1.3 | GO:0031527 | filopodium membrane(GO:0031527) |
0.3 | 4.8 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.3 | 3.9 | GO:0043203 | axon hillock(GO:0043203) |
0.3 | 14.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.3 | 2.1 | GO:0070695 | FHF complex(GO:0070695) |
0.3 | 2.4 | GO:0033391 | chromatoid body(GO:0033391) |
0.3 | 1.5 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.3 | 0.9 | GO:0002142 | stereocilia ankle link complex(GO:0002142) |
0.3 | 1.8 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.3 | 0.9 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
0.3 | 2.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.3 | 1.4 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.3 | 10.1 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.3 | 1.1 | GO:1990769 | proximal neuron projection(GO:1990769) |
0.3 | 4.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.3 | 1.1 | GO:0005901 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
0.3 | 3.3 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.3 | 1.6 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.3 | 0.8 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
0.3 | 2.4 | GO:0042587 | glycogen granule(GO:0042587) |
0.3 | 1.3 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
0.3 | 1.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.3 | 3.1 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.2 | 1.5 | GO:0005796 | Golgi lumen(GO:0005796) |
0.2 | 1.2 | GO:0001652 | granular component(GO:0001652) |
0.2 | 3.2 | GO:0046930 | pore complex(GO:0046930) |
0.2 | 1.2 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.2 | 1.0 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.2 | 1.5 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.2 | 1.4 | GO:0031415 | NatA complex(GO:0031415) |
0.2 | 1.2 | GO:0001533 | cornified envelope(GO:0001533) |
0.2 | 1.2 | GO:0032389 | MutLalpha complex(GO:0032389) |
0.2 | 0.7 | GO:0000801 | central element(GO:0000801) |
0.2 | 2.6 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.2 | 2.0 | GO:0061617 | MICOS complex(GO:0061617) |
0.2 | 0.4 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.2 | 9.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.2 | 3.3 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.2 | 1.9 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.2 | 1.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.2 | 12.5 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.2 | 1.8 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.2 | 2.0 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.2 | 1.5 | GO:0097427 | microtubule bundle(GO:0097427) |
0.2 | 0.6 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
0.2 | 1.1 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.2 | 1.5 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.2 | 6.0 | GO:0051233 | spindle midzone(GO:0051233) |
0.2 | 8.2 | GO:0031941 | filamentous actin(GO:0031941) |
0.2 | 3.0 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.2 | 1.9 | GO:0031931 | TORC1 complex(GO:0031931) |
0.2 | 4.3 | GO:0005921 | gap junction(GO:0005921) |
0.2 | 3.7 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.2 | 0.5 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
0.2 | 9.6 | GO:0005882 | intermediate filament(GO:0005882) |
0.2 | 1.6 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.2 | 3.7 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.2 | 0.8 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.2 | 3.3 | GO:0030914 | STAGA complex(GO:0030914) |
0.2 | 0.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.2 | 0.9 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.2 | 7.3 | GO:0031902 | late endosome membrane(GO:0031902) |
0.2 | 5.5 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
0.2 | 2.6 | GO:0072562 | blood microparticle(GO:0072562) |
0.2 | 1.5 | GO:0034709 | methylosome(GO:0034709) |
0.2 | 6.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 14.1 | GO:0043198 | dendritic shaft(GO:0043198) |
0.1 | 0.4 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
0.1 | 0.4 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.1 | 4.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 9.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.1 | 0.6 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
0.1 | 0.6 | GO:0098888 | extrinsic component of presynaptic membrane(GO:0098888) |
0.1 | 3.0 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.1 | 0.4 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.1 | 10.2 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
0.1 | 3.0 | GO:0005839 | proteasome core complex(GO:0005839) |
0.1 | 0.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.1 | 1.1 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
0.1 | 1.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 0.5 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.1 | 1.4 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.1 | 0.7 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.1 | 0.9 | GO:0005827 | polar microtubule(GO:0005827) |
0.1 | 1.5 | GO:0000974 | Prp19 complex(GO:0000974) |
0.1 | 0.6 | GO:0071817 | MMXD complex(GO:0071817) CIA complex(GO:0097361) |
0.1 | 6.8 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.1 | 0.9 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.1 | 1.1 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 26.7 | GO:0000139 | Golgi membrane(GO:0000139) |
0.1 | 0.5 | GO:0070852 | cell body fiber(GO:0070852) |
0.1 | 1.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.1 | 0.6 | GO:0097255 | R2TP complex(GO:0097255) |
0.1 | 0.3 | GO:0031533 | mRNA cap methyltransferase complex(GO:0031533) |
0.1 | 0.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.1 | 0.4 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
0.1 | 0.3 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
0.1 | 4.6 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.1 | 7.1 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
0.1 | 1.3 | GO:0005902 | microvillus(GO:0005902) |
0.1 | 1.8 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
0.1 | 0.8 | GO:0016272 | prefoldin complex(GO:0016272) |
0.1 | 1.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.1 | 2.6 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 0.5 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.1 | 1.1 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 5.2 | GO:0043197 | dendritic spine(GO:0043197) |
0.1 | 0.3 | GO:0016342 | catenin complex(GO:0016342) |
0.1 | 0.4 | GO:0097342 | ripoptosome(GO:0097342) |
0.1 | 0.7 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
0.1 | 0.9 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.1 | 1.9 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.1 | 1.0 | GO:0098797 | plasma membrane protein complex(GO:0098797) |
0.1 | 0.5 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 1.6 | GO:0005770 | late endosome(GO:0005770) |
0.1 | 5.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.1 | 0.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.1 | 0.8 | GO:0032040 | small-subunit processome(GO:0032040) |
0.1 | 0.6 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.1 | 2.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.1 | 7.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.1 | 0.4 | GO:0030057 | desmosome(GO:0030057) |
0.1 | 0.8 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.1 | 3.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.8 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 1.4 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.0 | 1.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.6 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.0 | 0.2 | GO:0097447 | dendritic tree(GO:0097447) |
0.0 | 1.0 | GO:0032589 | neuron projection membrane(GO:0032589) |
0.0 | 12.4 | GO:0014069 | postsynaptic density(GO:0014069) |
0.0 | 0.4 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.6 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 4.1 | GO:0044306 | neuron projection terminus(GO:0044306) |
0.0 | 2.8 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 1.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 5.4 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 0.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.2 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.0 | 0.6 | GO:0044439 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
0.0 | 0.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.3 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.0 | 0.9 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.3 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.0 | 2.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.9 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.0 | 6.5 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
0.0 | 1.4 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.5 | GO:0030667 | secretory granule membrane(GO:0030667) |
0.0 | 2.4 | GO:0034399 | nuclear periphery(GO:0034399) |
0.0 | 0.1 | GO:0030016 | myofibril(GO:0030016) |
0.0 | 1.4 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 1.0 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.6 | GO:0005840 | ribosome(GO:0005840) |
0.0 | 2.6 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 0.1 | GO:0031105 | septin complex(GO:0031105) |
0.0 | 1.3 | GO:0009986 | cell surface(GO:0009986) |
0.0 | 0.3 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 0.4 | GO:0005903 | brush border(GO:0005903) |
0.0 | 0.1 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.1 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 0.5 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 1.4 | GO:0043025 | neuronal cell body(GO:0043025) |
0.0 | 1.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 4.5 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.0 | 24.8 | GO:0070062 | extracellular exosome(GO:0070062) |
0.0 | 0.6 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 10.8 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
3.0 | 18.1 | GO:0043426 | MRF binding(GO:0043426) |
2.9 | 11.4 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
2.7 | 8.0 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
2.6 | 10.2 | GO:0031721 | haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721) |
2.4 | 14.1 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
1.9 | 13.5 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
1.8 | 24.0 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
1.8 | 5.3 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
1.7 | 8.6 | GO:0097643 | amylin receptor activity(GO:0097643) |
1.5 | 4.6 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
1.5 | 7.6 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
1.5 | 4.5 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
1.4 | 7.2 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
1.3 | 3.9 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
1.2 | 4.8 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
1.2 | 4.7 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
1.1 | 4.6 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
1.1 | 6.4 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
1.1 | 3.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
1.0 | 7.3 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
1.0 | 7.0 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
1.0 | 27.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
1.0 | 3.9 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
1.0 | 2.9 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
0.9 | 3.7 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
0.9 | 3.7 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.9 | 2.6 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.9 | 7.7 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
0.8 | 4.1 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
0.8 | 2.4 | GO:0031403 | lithium ion binding(GO:0031403) |
0.8 | 2.3 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
0.8 | 3.0 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.7 | 2.2 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
0.7 | 2.2 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
0.7 | 6.5 | GO:0034711 | inhibin binding(GO:0034711) |
0.7 | 2.1 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.7 | 2.1 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.7 | 3.4 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.7 | 3.4 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.7 | 11.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.6 | 3.9 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
0.6 | 10.3 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.6 | 1.9 | GO:0015232 | heme transporter activity(GO:0015232) |
0.6 | 7.8 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.6 | 2.4 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.6 | 1.7 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
0.6 | 2.2 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.5 | 3.3 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.5 | 9.2 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.5 | 10.8 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.5 | 2.7 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
0.5 | 1.6 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.5 | 2.6 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.5 | 1.5 | GO:0009383 | rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) |
0.5 | 5.5 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
0.5 | 1.0 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.5 | 1.9 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
0.5 | 6.3 | GO:0015643 | toxic substance binding(GO:0015643) |
0.5 | 2.4 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.5 | 1.4 | GO:0009374 | biotin binding(GO:0009374) |
0.5 | 2.3 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.5 | 1.4 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
0.4 | 2.2 | GO:0072349 | modified amino acid transmembrane transporter activity(GO:0072349) |
0.4 | 1.8 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
0.4 | 2.7 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.4 | 6.2 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.4 | 3.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.4 | 3.5 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.4 | 2.6 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.4 | 1.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.4 | 1.7 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
0.4 | 1.2 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
0.4 | 7.9 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.4 | 7.7 | GO:0043274 | phospholipase binding(GO:0043274) |
0.4 | 1.9 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.4 | 1.5 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.4 | 1.8 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.4 | 11.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.4 | 15.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.4 | 5.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.4 | 1.5 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.4 | 3.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.4 | 3.5 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.4 | 1.1 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.3 | 1.4 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
0.3 | 2.7 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.3 | 1.0 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.3 | 2.0 | GO:0030375 | thyroid hormone receptor coactivator activity(GO:0030375) |
0.3 | 2.6 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.3 | 1.6 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.3 | 3.9 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.3 | 0.9 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
0.3 | 2.4 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
0.3 | 1.2 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.3 | 0.9 | GO:0036004 | GAF domain binding(GO:0036004) |
0.3 | 1.8 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.3 | 1.2 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
0.3 | 1.2 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.3 | 1.2 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
0.3 | 6.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.3 | 1.1 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.3 | 1.4 | GO:0044020 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
0.3 | 0.8 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
0.3 | 3.2 | GO:0000182 | rDNA binding(GO:0000182) |
0.3 | 1.1 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.3 | 0.8 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.3 | 7.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.3 | 5.1 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.3 | 0.8 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.3 | 4.3 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.2 | 1.2 | GO:0002060 | purine nucleobase binding(GO:0002060) |
0.2 | 1.5 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.2 | 2.9 | GO:0010181 | FMN binding(GO:0010181) |
0.2 | 2.2 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.2 | 2.2 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.2 | 0.7 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
0.2 | 1.4 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
0.2 | 0.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.2 | 5.2 | GO:0071949 | FAD binding(GO:0071949) |
0.2 | 3.5 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.2 | 0.9 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.2 | 1.6 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.2 | 0.7 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
0.2 | 2.0 | GO:0071253 | connexin binding(GO:0071253) |
0.2 | 2.7 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.2 | 1.3 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.2 | 1.1 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.2 | 3.2 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.2 | 1.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.2 | 7.8 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.2 | 1.5 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.2 | 3.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.2 | 0.6 | GO:0030911 | TPR domain binding(GO:0030911) |
0.2 | 1.2 | GO:0015929 | hexosaminidase activity(GO:0015929) |
0.2 | 4.1 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.2 | 1.2 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.2 | 0.6 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
0.2 | 1.8 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.2 | 1.0 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.2 | 3.9 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.2 | 1.7 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.2 | 1.9 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.2 | 0.9 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
0.2 | 1.8 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.2 | 0.4 | GO:0051990 | (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990) |
0.2 | 28.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.2 | 0.7 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.2 | 3.8 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.2 | 0.7 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
0.2 | 3.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.2 | 1.8 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.2 | 0.5 | GO:0016635 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
0.2 | 4.7 | GO:0008378 | galactosyltransferase activity(GO:0008378) |
0.2 | 2.9 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
0.2 | 1.9 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.2 | 0.3 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.2 | 2.0 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.2 | 1.1 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.2 | 1.4 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
0.2 | 2.0 | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) |
0.2 | 7.5 | GO:0015485 | cholesterol binding(GO:0015485) |
0.2 | 0.5 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
0.1 | 0.4 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.1 | 2.7 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 0.4 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
0.1 | 0.4 | GO:0035939 | microsatellite binding(GO:0035939) |
0.1 | 0.4 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.1 | 1.9 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
0.1 | 0.4 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
0.1 | 0.6 | GO:0008443 | phosphofructokinase activity(GO:0008443) |
0.1 | 0.8 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) |
0.1 | 0.7 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 0.5 | GO:0008948 | oxaloacetate decarboxylase activity(GO:0008948) |
0.1 | 4.2 | GO:0020037 | heme binding(GO:0020037) |
0.1 | 4.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 1.3 | GO:0043495 | protein anchor(GO:0043495) |
0.1 | 1.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.1 | 0.9 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 4.7 | GO:0005507 | copper ion binding(GO:0005507) |
0.1 | 0.4 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
0.1 | 0.5 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
0.1 | 0.4 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
0.1 | 0.7 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.1 | 0.2 | GO:0004046 | aminoacylase activity(GO:0004046) |
0.1 | 0.7 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.1 | 6.7 | GO:0000049 | tRNA binding(GO:0000049) |
0.1 | 1.6 | GO:0048156 | tau protein binding(GO:0048156) |
0.1 | 2.2 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.1 | 8.1 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.1 | 0.4 | GO:0035242 | histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
0.1 | 5.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 1.1 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.1 | 0.6 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.1 | 0.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.1 | 1.9 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.1 | 6.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.1 | 0.3 | GO:0005118 | sevenless binding(GO:0005118) |
0.1 | 0.8 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
0.1 | 0.4 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 2.8 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.1 | 0.4 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
0.1 | 0.6 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.1 | 0.5 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.1 | 2.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.1 | 1.2 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.1 | 0.5 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
0.1 | 0.6 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
0.1 | 1.4 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
0.1 | 0.3 | GO:0004482 | mRNA (guanine-N7-)-methyltransferase activity(GO:0004482) |
0.1 | 0.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 1.5 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 3.5 | GO:0004497 | monooxygenase activity(GO:0004497) |
0.1 | 0.4 | GO:0030984 | kininogen binding(GO:0030984) |
0.1 | 1.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 0.4 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.1 | 0.8 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.1 | 1.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.1 | 0.3 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.1 | 0.4 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.1 | 0.3 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.1 | 0.9 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.1 | 0.3 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
0.1 | 0.7 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.1 | 2.1 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.1 | 2.1 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
0.1 | 0.5 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.1 | 0.6 | GO:0043140 | ATP-dependent 3'-5' DNA helicase activity(GO:0043140) |
0.1 | 1.4 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.1 | 1.4 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 0.6 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.1 | 0.2 | GO:0008527 | taste receptor activity(GO:0008527) |
0.1 | 0.5 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.1 | 1.6 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.1 | 0.4 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.1 | 0.6 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.1 | 0.8 | GO:0048038 | quinone binding(GO:0048038) |
0.1 | 0.3 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
0.1 | 0.7 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.1 | 0.5 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
0.1 | 1.4 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.1 | 0.4 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.1 | 0.8 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.1 | 3.8 | GO:0030507 | spectrin binding(GO:0030507) |
0.1 | 0.4 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.1 | 2.2 | GO:0030552 | cAMP binding(GO:0030552) |
0.1 | 0.4 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.1 | 0.2 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.1 | 0.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.1 | 1.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.1 | 5.6 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.1 | 1.2 | GO:0004970 | ionotropic glutamate receptor activity(GO:0004970) extracellular-glutamate-gated ion channel activity(GO:0005234) |
0.1 | 1.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.1 | 0.2 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.1 | 0.3 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
0.1 | 2.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.1 | 2.3 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.1 | 1.1 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
0.1 | 0.8 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
0.1 | 2.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.1 | 2.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 0.2 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
0.1 | 2.3 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.1 | 1.2 | GO:0008173 | RNA methyltransferase activity(GO:0008173) |
0.1 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 1.0 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 0.5 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.6 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
0.0 | 0.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.4 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.2 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
0.0 | 1.1 | GO:0001968 | fibronectin binding(GO:0001968) |
0.0 | 4.6 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.2 | GO:0042979 | ornithine decarboxylase regulator activity(GO:0042979) |
0.0 | 2.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 1.3 | GO:0009055 | electron carrier activity(GO:0009055) |
0.0 | 1.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.3 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.0 | 0.6 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 0.3 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.0 | 0.3 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
0.0 | 0.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.1 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
0.0 | 0.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.0 | 0.8 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.0 | 2.6 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.0 | 3.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.8 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.0 | 0.4 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
0.0 | 0.0 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
0.0 | 0.4 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
0.0 | 0.6 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.0 | 1.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.9 | GO:0005496 | steroid binding(GO:0005496) |
0.0 | 1.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.3 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.6 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.7 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
0.0 | 1.9 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.1 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.0 | 0.9 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
0.0 | 1.1 | GO:0005506 | iron ion binding(GO:0005506) |
0.0 | 0.1 | GO:0043199 | sulfate binding(GO:0043199) |
0.0 | 0.2 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.3 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.4 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.0 | 1.5 | GO:0016798 | hydrolase activity, acting on glycosyl bonds(GO:0016798) |
0.0 | 0.5 | GO:0019843 | rRNA binding(GO:0019843) |
0.0 | 0.2 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.0 | 0.3 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 0.5 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.0 | 0.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.4 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.0 | 0.2 | GO:0070840 | dynein complex binding(GO:0070840) |
0.0 | 0.0 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
0.0 | 0.5 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 0.2 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.3 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.0 | 0.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.3 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 0.1 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) |
0.0 | 0.1 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.1 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
0.0 | 1.2 | GO:0008201 | heparin binding(GO:0008201) |
0.0 | 3.6 | GO:0003924 | GTPase activity(GO:0003924) |
0.0 | 0.1 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.0 | 0.1 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 0.1 | GO:0015149 | hexose transmembrane transporter activity(GO:0015149) |
0.0 | 0.3 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.2 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 4.7 | PID_IFNG_PATHWAY | IFN-gamma pathway |
1.3 | 24.6 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
1.0 | 17.5 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.6 | 1.1 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.3 | 1.3 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.3 | 16.0 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.3 | 5.7 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.3 | 10.8 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.2 | 16.2 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.2 | 3.1 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.2 | 7.7 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.2 | 9.0 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.2 | 6.0 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
0.2 | 3.2 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.2 | 2.6 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.2 | 2.8 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 0.7 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.1 | 9.4 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.1 | 2.7 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.1 | 1.5 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.1 | 1.2 | PID_MYC_PATHWAY | C-MYC pathway |
0.1 | 9.7 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
0.1 | 5.3 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.1 | 2.3 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.1 | 5.3 | PID_BMP_PATHWAY | BMP receptor signaling |
0.1 | 0.7 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.1 | 3.3 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.1 | 15.5 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.1 | 1.6 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.1 | 1.4 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
0.1 | 1.0 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.1 | 16.3 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.1 | 1.0 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.1 | 1.3 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.1 | 1.6 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.1 | 1.7 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.1 | 2.2 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
0.1 | 1.3 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.1 | 0.1 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
0.1 | 0.5 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 0.4 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.1 | 1.9 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
0.1 | 9.0 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 0.7 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.1 | 3.1 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.1 | 3.4 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.1 | 0.7 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.1 | 0.5 | PID_TXA2PATHWAY | Thromboxane A2 receptor signaling |
0.1 | 0.3 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
0.0 | 1.0 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 0.5 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 4.2 | NABA_MATRISOME_ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
0.0 | 0.5 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.0 | 0.8 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.5 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
0.0 | 1.7 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.0 | 0.3 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
0.0 | 0.5 | ST_FAS_SIGNALING_PATHWAY | Fas Signaling Pathway |
0.0 | 0.5 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 0.5 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 0.1 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 0.2 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 1.7 | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | Genes involved in Transferrin endocytosis and recycling |
1.6 | 6.5 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
1.6 | 1.6 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
1.2 | 14.9 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
1.1 | 25.7 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
1.0 | 15.7 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.8 | 7.0 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.6 | 27.6 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.6 | 6.0 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.5 | 4.8 | REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | Genes involved in Acetylcholine Binding And Downstream Events |
0.5 | 9.2 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.5 | 15.6 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.4 | 11.6 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.4 | 5.4 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.4 | 12.6 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.4 | 6.0 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.4 | 10.0 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.4 | 3.5 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.3 | 23.3 | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
0.3 | 9.5 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.3 | 1.9 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.3 | 4.3 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.3 | 4.8 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.3 | 2.3 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.3 | 7.2 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.3 | 10.9 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.2 | 5.4 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.2 | 2.1 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.2 | 18.8 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.2 | 4.0 | REACTOME_TRNA_AMINOACYLATION | Genes involved in tRNA Aminoacylation |
0.2 | 6.9 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.2 | 8.2 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.2 | 4.1 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.2 | 7.2 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.2 | 7.1 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
0.2 | 5.0 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.2 | 0.8 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
0.2 | 3.0 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.2 | 4.4 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.2 | 13.5 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
0.2 | 4.6 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.2 | 1.5 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.2 | 6.9 | REACTOME_METABOLISM_OF_NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
0.1 | 2.3 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
0.1 | 0.3 | REACTOME_MRNA_CAPPING | Genes involved in mRNA Capping |
0.1 | 2.1 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.1 | 2.0 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.1 | 1.4 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.1 | 1.3 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.1 | 2.3 | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | Genes involved in Inwardly rectifying K+ channels |
0.1 | 2.6 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.1 | 2.2 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.1 | 18.2 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 1.8 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
0.1 | 2.0 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 0.8 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 1.4 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.1 | 4.9 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.1 | 5.7 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.1 | 6.5 | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | Genes involved in NCAM signaling for neurite out-growth |
0.1 | 2.2 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.1 | 7.3 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
0.1 | 1.4 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.1 | 1.7 | REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM | Genes involved in Keratan sulfate/keratin metabolism |
0.1 | 2.4 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.1 | 1.6 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.1 | 0.6 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.1 | 0.7 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.1 | 0.9 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.1 | 1.5 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | Genes involved in Post NMDA receptor activation events |
0.1 | 1.2 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.1 | 0.7 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.1 | 1.1 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
0.1 | 1.0 | REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
0.1 | 1.9 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.1 | 0.6 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.1 | 0.4 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.1 | 1.0 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.1 | 1.6 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.4 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 2.0 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.1 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 1.1 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 2.9 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.8 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 2.7 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.2 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.0 | 1.7 | REACTOME_TRANSLATION | Genes involved in Translation |
0.0 | 0.4 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 0.7 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 0.4 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 0.3 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.3 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.0 | 0.1 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.2 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 1.2 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
0.0 | 0.1 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 0.1 | REACTOME_DAG_AND_IP3_SIGNALING | Genes involved in DAG and IP3 signaling |
0.0 | 0.1 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.6 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
0.0 | 1.5 | REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION | Genes involved in PPARA Activates Gene Expression |
0.0 | 0.4 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.0 | 0.5 | REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
0.0 | 0.8 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 0.5 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.1 | REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
0.0 | 0.1 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.0 | 0.2 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.4 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
0.0 | 0.5 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 0.1 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
0.0 | 1.0 | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | Genes involved in G alpha (q) signalling events |