Motif ID: Hic1
Z-value: 1.380
Transcription factors associated with Hic1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hic1 | ENSMUSG00000043099.4 | Hic1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.2 | 15.7 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
3.1 | 15.6 | GO:0071692 | protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) |
2.8 | 2.8 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) |
2.7 | 18.6 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
2.7 | 8.0 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
2.6 | 7.9 | GO:0035604 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529) |
2.5 | 7.5 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
2.3 | 7.0 | GO:0071492 | cellular response to UV-A(GO:0071492) |
2.3 | 6.8 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
2.2 | 6.6 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
2.1 | 6.2 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
2.0 | 6.1 | GO:0086047 | membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) |
2.0 | 8.0 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
1.9 | 3.8 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
1.9 | 1.9 | GO:0035844 | cloaca development(GO:0035844) |
1.8 | 5.5 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
1.7 | 7.0 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
1.7 | 9.9 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
1.6 | 3.3 | GO:0097112 | gamma-aminobutyric acid receptor clustering(GO:0097112) |
1.6 | 4.8 | GO:0070650 | actin filament bundle distribution(GO:0070650) |
1.5 | 7.3 | GO:1990034 | calcium ion export from cell(GO:1990034) |
1.5 | 4.4 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
1.5 | 4.4 | GO:0010512 | negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) |
1.4 | 11.5 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
1.4 | 5.7 | GO:0051866 | general adaptation syndrome(GO:0051866) |
1.3 | 5.3 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
1.3 | 5.2 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
1.3 | 3.8 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
1.2 | 3.7 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
1.2 | 3.6 | GO:2000705 | regulation of dense core granule biogenesis(GO:2000705) |
1.2 | 7.1 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
1.2 | 5.8 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
1.1 | 3.4 | GO:0071317 | cellular response to isoquinoline alkaloid(GO:0071317) |
1.1 | 3.3 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
1.1 | 4.4 | GO:0021586 | pons maturation(GO:0021586) |
1.1 | 21.8 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
1.1 | 15.0 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
1.1 | 3.2 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
1.1 | 4.2 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
1.1 | 5.3 | GO:0043987 | histone H3-S10 phosphorylation(GO:0043987) |
1.0 | 2.1 | GO:0086048 | membrane depolarization during bundle of His cell action potential(GO:0086048) |
1.0 | 6.3 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
1.0 | 3.1 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
1.0 | 3.1 | GO:1990927 | calcium ion regulated lysosome exocytosis(GO:1990927) |
1.0 | 13.0 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
1.0 | 2.0 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
1.0 | 4.9 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
1.0 | 4.9 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
1.0 | 3.9 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
1.0 | 16.5 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
1.0 | 5.8 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
1.0 | 3.9 | GO:1903294 | regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296) |
1.0 | 2.9 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
0.9 | 2.8 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
0.9 | 2.8 | GO:0072194 | sensory perception of touch(GO:0050975) kidney smooth muscle tissue development(GO:0072194) |
0.9 | 0.9 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
0.9 | 6.3 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.9 | 2.7 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
0.9 | 2.7 | GO:0061526 | acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526) |
0.9 | 6.2 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
0.9 | 15.7 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.9 | 1.7 | GO:0061744 | motor behavior(GO:0061744) |
0.8 | 2.5 | GO:0031133 | regulation of axon diameter(GO:0031133) |
0.8 | 3.4 | GO:0001956 | positive regulation of neurotransmitter secretion(GO:0001956) |
0.8 | 2.5 | GO:1904978 | regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
0.8 | 2.5 | GO:1905223 | epicardium morphogenesis(GO:1905223) |
0.8 | 3.3 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.8 | 7.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.8 | 6.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.8 | 2.4 | GO:0099548 | drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548) |
0.8 | 3.2 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) |
0.8 | 14.1 | GO:0006491 | N-glycan processing(GO:0006491) |
0.8 | 2.3 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.8 | 3.0 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
0.7 | 2.2 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627) |
0.7 | 13.2 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.7 | 2.9 | GO:0072362 | regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
0.7 | 0.7 | GO:0014834 | skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834) |
0.7 | 2.1 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
0.7 | 2.7 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.7 | 0.7 | GO:0007567 | parturition(GO:0007567) |
0.7 | 17.8 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.7 | 2.0 | GO:0014916 | regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) |
0.7 | 2.6 | GO:1905167 | astrocyte activation involved in immune response(GO:0002265) positive regulation of lysosomal protein catabolic process(GO:1905167) |
0.6 | 1.9 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
0.6 | 2.6 | GO:0036015 | response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) |
0.6 | 1.9 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
0.6 | 6.4 | GO:0046959 | habituation(GO:0046959) |
0.6 | 5.1 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
0.6 | 1.9 | GO:1905169 | protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171) |
0.6 | 8.7 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
0.6 | 4.9 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.6 | 2.4 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.6 | 0.6 | GO:0035799 | ureter maturation(GO:0035799) |
0.6 | 1.7 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
0.6 | 1.7 | GO:0046878 | positive regulation of saliva secretion(GO:0046878) |
0.6 | 3.4 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.6 | 6.7 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.5 | 3.8 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
0.5 | 1.1 | GO:0042713 | sperm ejaculation(GO:0042713) |
0.5 | 3.2 | GO:0016266 | O-glycan processing(GO:0016266) |
0.5 | 0.5 | GO:0061349 | planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) |
0.5 | 2.1 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
0.5 | 3.7 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
0.5 | 4.2 | GO:0070314 | G1 to G0 transition(GO:0070314) |
0.5 | 4.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.5 | 2.1 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.5 | 2.0 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
0.5 | 4.0 | GO:0031053 | primary miRNA processing(GO:0031053) |
0.5 | 3.0 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.5 | 4.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.5 | 2.4 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.5 | 2.0 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
0.5 | 7.3 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
0.5 | 0.5 | GO:0014053 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) |
0.5 | 0.5 | GO:1901608 | regulation of vesicle transport along microtubule(GO:1901608) |
0.5 | 2.9 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.5 | 6.2 | GO:0070842 | aggresome assembly(GO:0070842) |
0.5 | 1.9 | GO:0097477 | NMDA glutamate receptor clustering(GO:0097114) lateral motor column neuron migration(GO:0097477) |
0.5 | 3.8 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
0.5 | 1.4 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
0.5 | 2.4 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.5 | 2.8 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.5 | 2.3 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
0.4 | 1.8 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
0.4 | 3.5 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
0.4 | 3.1 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.4 | 4.4 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.4 | 2.2 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.4 | 1.7 | GO:0072602 | interleukin-4 secretion(GO:0072602) |
0.4 | 3.0 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
0.4 | 1.3 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
0.4 | 4.2 | GO:0045634 | regulation of melanocyte differentiation(GO:0045634) |
0.4 | 3.4 | GO:0014850 | response to muscle activity(GO:0014850) |
0.4 | 4.2 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.4 | 1.3 | GO:0051933 | regulation of DNA-templated transcription, termination(GO:0031554) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
0.4 | 3.3 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.4 | 2.4 | GO:0019985 | translesion synthesis(GO:0019985) |
0.4 | 1.6 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
0.4 | 2.4 | GO:0070100 | negative regulation of chemokine-mediated signaling pathway(GO:0070100) |
0.4 | 0.8 | GO:0071494 | cellular response to UV-C(GO:0071494) |
0.4 | 2.4 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.4 | 2.0 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.4 | 2.3 | GO:2001184 | regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184) |
0.4 | 1.2 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
0.4 | 3.1 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
0.4 | 2.3 | GO:0048069 | eye pigmentation(GO:0048069) |
0.4 | 4.2 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.4 | 1.1 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.4 | 1.1 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.4 | 1.4 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
0.4 | 0.4 | GO:0032916 | positive regulation of transforming growth factor beta3 production(GO:0032916) |
0.4 | 0.4 | GO:0007354 | zygotic determination of anterior/posterior axis, embryo(GO:0007354) |
0.4 | 2.9 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
0.4 | 1.4 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
0.4 | 0.4 | GO:0060423 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) |
0.4 | 3.2 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
0.3 | 1.4 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
0.3 | 2.1 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
0.3 | 2.0 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.3 | 3.3 | GO:0042711 | maternal behavior(GO:0042711) |
0.3 | 1.0 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.3 | 1.6 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
0.3 | 1.6 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
0.3 | 1.9 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.3 | 3.2 | GO:0006968 | cellular defense response(GO:0006968) |
0.3 | 2.2 | GO:0033625 | positive regulation of integrin activation(GO:0033625) |
0.3 | 3.1 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.3 | 1.6 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
0.3 | 0.9 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
0.3 | 1.8 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.3 | 8.9 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.3 | 2.5 | GO:0031424 | keratinization(GO:0031424) |
0.3 | 0.9 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
0.3 | 6.7 | GO:0008209 | androgen metabolic process(GO:0008209) |
0.3 | 1.2 | GO:1903898 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
0.3 | 1.8 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
0.3 | 1.8 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.3 | 1.5 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
0.3 | 0.9 | GO:0019046 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
0.3 | 5.6 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.3 | 2.6 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
0.3 | 0.9 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.3 | 1.8 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
0.3 | 1.4 | GO:0090669 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669) |
0.3 | 1.4 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.3 | 1.7 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
0.3 | 1.7 | GO:0031034 | myosin filament assembly(GO:0031034) |
0.3 | 4.2 | GO:0051639 | actin filament network formation(GO:0051639) |
0.3 | 1.1 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.3 | 0.8 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
0.3 | 14.8 | GO:0034605 | cellular response to heat(GO:0034605) |
0.3 | 3.6 | GO:0071625 | vocalization behavior(GO:0071625) |
0.3 | 2.8 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.3 | 1.1 | GO:0019348 | dolichol metabolic process(GO:0019348) |
0.3 | 1.7 | GO:0032439 | endosome localization(GO:0032439) |
0.3 | 7.4 | GO:2000463 | positive regulation of excitatory postsynaptic potential(GO:2000463) |
0.3 | 20.3 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
0.3 | 1.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.3 | 0.8 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
0.3 | 1.6 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
0.3 | 0.8 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
0.3 | 6.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.3 | 1.8 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.3 | 2.8 | GO:0033005 | positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.3 | 1.8 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.3 | 2.3 | GO:0051764 | actin crosslink formation(GO:0051764) |
0.3 | 0.5 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.3 | 3.3 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.3 | 1.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.3 | 2.3 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.2 | 0.7 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
0.2 | 1.0 | GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) |
0.2 | 8.1 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
0.2 | 2.9 | GO:0006012 | galactose metabolic process(GO:0006012) |
0.2 | 0.7 | GO:2000850 | protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
0.2 | 2.2 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
0.2 | 0.7 | GO:0015886 | heme transport(GO:0015886) |
0.2 | 6.4 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
0.2 | 1.4 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.2 | 1.4 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.2 | 0.7 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
0.2 | 8.8 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.2 | 14.9 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.2 | 0.7 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
0.2 | 2.3 | GO:0001964 | startle response(GO:0001964) |
0.2 | 1.1 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
0.2 | 4.9 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.2 | 1.6 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
0.2 | 3.3 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.2 | 1.6 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.2 | 0.7 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.2 | 14.3 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.2 | 0.9 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
0.2 | 0.6 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
0.2 | 3.2 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.2 | 0.9 | GO:0014846 | gastro-intestinal system smooth muscle contraction(GO:0014831) esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
0.2 | 1.1 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.2 | 0.9 | GO:0010694 | positive regulation of alkaline phosphatase activity(GO:0010694) |
0.2 | 1.1 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.2 | 2.8 | GO:1901798 | positive regulation of signal transduction by p53 class mediator(GO:1901798) |
0.2 | 1.1 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
0.2 | 0.6 | GO:0090272 | negative regulation of fibroblast growth factor production(GO:0090272) |
0.2 | 2.5 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
0.2 | 0.6 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
0.2 | 0.4 | GO:0009405 | pathogenesis(GO:0009405) |
0.2 | 1.7 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.2 | 2.9 | GO:0008272 | sulfate transport(GO:0008272) |
0.2 | 2.3 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.2 | 0.4 | GO:1902022 | L-lysine transport(GO:1902022) |
0.2 | 0.8 | GO:0018202 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202) |
0.2 | 2.0 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.2 | 1.2 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.2 | 2.8 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065) |
0.2 | 3.0 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.2 | 1.8 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
0.2 | 0.6 | GO:0045869 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869) |
0.2 | 2.2 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.2 | 1.9 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
0.2 | 2.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.2 | 0.4 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
0.2 | 3.2 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.2 | 1.1 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
0.2 | 0.8 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
0.2 | 1.5 | GO:0034389 | lipid particle organization(GO:0034389) |
0.2 | 4.6 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.2 | 0.6 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031) |
0.2 | 1.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.2 | 0.9 | GO:0034214 | protein hexamerization(GO:0034214) |
0.2 | 0.9 | GO:0030952 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952) |
0.2 | 0.5 | GO:0044208 | AMP biosynthetic process(GO:0006167) 'de novo' AMP biosynthetic process(GO:0044208) |
0.2 | 5.0 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.2 | 0.5 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
0.2 | 2.8 | GO:0010954 | positive regulation of protein processing(GO:0010954) |
0.2 | 0.7 | GO:0010820 | positive regulation of T cell chemotaxis(GO:0010820) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
0.2 | 0.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
0.2 | 0.8 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
0.2 | 0.3 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.2 | 0.3 | GO:0006534 | cysteine metabolic process(GO:0006534) serine family amino acid metabolic process(GO:0009069) homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814) |
0.2 | 0.7 | GO:0070417 | regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) cellular response to cold(GO:0070417) |
0.2 | 0.7 | GO:0044331 | cell-cell adhesion mediated by cadherin(GO:0044331) |
0.2 | 1.1 | GO:0007492 | endoderm development(GO:0007492) |
0.2 | 0.7 | GO:0009414 | response to water deprivation(GO:0009414) |
0.2 | 1.1 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.2 | 0.5 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.2 | 1.1 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.2 | 0.6 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.2 | 1.6 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.2 | 6.6 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
0.2 | 5.4 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.2 | 1.6 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
0.2 | 1.7 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
0.2 | 0.3 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
0.2 | 0.8 | GO:0031297 | replication fork processing(GO:0031297) |
0.2 | 1.1 | GO:0003044 | regulation of systemic arterial blood pressure mediated by a chemical signal(GO:0003044) |
0.2 | 0.9 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
0.2 | 0.6 | GO:0035927 | RNA import into mitochondrion(GO:0035927) |
0.2 | 0.6 | GO:1900368 | regulation of RNA interference(GO:1900368) |
0.2 | 2.0 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
0.2 | 1.8 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.2 | 1.5 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.1 | 0.7 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
0.1 | 0.6 | GO:0089700 | protein kinase D signaling(GO:0089700) |
0.1 | 0.4 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
0.1 | 0.4 | GO:2000630 | positive regulation of miRNA metabolic process(GO:2000630) |
0.1 | 5.5 | GO:0019228 | neuronal action potential(GO:0019228) |
0.1 | 1.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.1 | 0.4 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
0.1 | 1.7 | GO:0097186 | amelogenesis(GO:0097186) |
0.1 | 1.4 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
0.1 | 3.0 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.1 | 2.9 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.1 | 1.9 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
0.1 | 0.8 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.1 | 0.8 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.1 | 3.2 | GO:0001706 | endoderm formation(GO:0001706) |
0.1 | 2.5 | GO:0043113 | receptor clustering(GO:0043113) |
0.1 | 1.3 | GO:0008063 | Toll signaling pathway(GO:0008063) |
0.1 | 1.3 | GO:0045109 | intermediate filament organization(GO:0045109) |
0.1 | 1.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.1 | 1.0 | GO:0010919 | regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
0.1 | 6.0 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
0.1 | 2.1 | GO:0051205 | protein insertion into membrane(GO:0051205) |
0.1 | 2.8 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
0.1 | 0.4 | GO:0051030 | snRNA transport(GO:0051030) |
0.1 | 1.2 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
0.1 | 3.1 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
0.1 | 0.5 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.1 | 0.5 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
0.1 | 0.8 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 2.1 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
0.1 | 0.5 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.1 | 1.7 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.1 | 0.1 | GO:0072367 | regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) |
0.1 | 2.5 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.1 | 0.5 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
0.1 | 0.9 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.1 | 0.6 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
0.1 | 0.5 | GO:0048631 | skeletal muscle tissue growth(GO:0048630) regulation of skeletal muscle tissue growth(GO:0048631) |
0.1 | 0.9 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.1 | 0.5 | GO:0071340 | skeletal muscle acetylcholine-gated channel clustering(GO:0071340) |
0.1 | 1.2 | GO:0030818 | negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) |
0.1 | 0.4 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.1 | 0.3 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
0.1 | 0.5 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.1 | 0.2 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
0.1 | 0.3 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
0.1 | 4.5 | GO:0007416 | synapse assembly(GO:0007416) |
0.1 | 1.0 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
0.1 | 4.4 | GO:0015914 | phospholipid transport(GO:0015914) |
0.1 | 0.4 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
0.1 | 0.7 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.1 | 1.6 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
0.1 | 0.3 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.1 | 1.0 | GO:0060749 | mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377) |
0.1 | 0.6 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
0.1 | 0.7 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
0.1 | 0.3 | GO:2000642 | negative regulation of vacuolar transport(GO:1903336) negative regulation of early endosome to late endosome transport(GO:2000642) |
0.1 | 0.3 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
0.1 | 0.2 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
0.1 | 1.6 | GO:0006677 | glycosylceramide metabolic process(GO:0006677) |
0.1 | 0.6 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.1 | 1.5 | GO:0033344 | cholesterol efflux(GO:0033344) |
0.1 | 0.4 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
0.1 | 1.1 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.1 | 0.9 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
0.1 | 0.4 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181) |
0.1 | 0.5 | GO:0060347 | heart trabecula formation(GO:0060347) |
0.1 | 1.3 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.1 | 0.4 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
0.1 | 0.6 | GO:0008228 | opsonization(GO:0008228) |
0.1 | 2.9 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.1 | 2.1 | GO:0048008 | platelet-derived growth factor receptor signaling pathway(GO:0048008) |
0.1 | 0.3 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
0.1 | 1.1 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
0.1 | 0.5 | GO:0006517 | protein deglycosylation(GO:0006517) |
0.1 | 0.3 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.1 | 0.5 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
0.1 | 1.4 | GO:0046034 | ATP metabolic process(GO:0046034) |
0.1 | 0.2 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.1 | 1.3 | GO:0002021 | response to dietary excess(GO:0002021) |
0.1 | 0.8 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.1 | 0.4 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
0.1 | 0.8 | GO:0006415 | translational termination(GO:0006415) |
0.1 | 0.3 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
0.1 | 1.5 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.1 | 0.2 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
0.1 | 1.5 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.1 | 9.1 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
0.1 | 0.5 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.1 | 0.2 | GO:0046032 | ADP catabolic process(GO:0046032) |
0.1 | 0.2 | GO:0035754 | B cell chemotaxis(GO:0035754) |
0.1 | 3.8 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
0.1 | 1.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.1 | 0.3 | GO:1901970 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
0.1 | 0.3 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
0.1 | 0.4 | GO:0006265 | DNA topological change(GO:0006265) |
0.1 | 0.2 | GO:0010046 | response to mycotoxin(GO:0010046) |
0.1 | 1.4 | GO:0055013 | cardiac muscle cell development(GO:0055013) |
0.1 | 0.4 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.1 | 1.6 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 1.5 | GO:0046785 | microtubule polymerization(GO:0046785) |
0.1 | 1.0 | GO:0015858 | nucleoside transport(GO:0015858) |
0.1 | 1.2 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.1 | 0.7 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
0.1 | 0.7 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.1 | 0.3 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.1 | 0.7 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
0.1 | 0.3 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
0.1 | 0.6 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.1 | 0.3 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
0.1 | 0.1 | GO:0002329 | immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329) |
0.1 | 0.6 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.1 | 0.3 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 0.2 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.1 | 1.3 | GO:0008542 | visual learning(GO:0008542) |
0.1 | 0.3 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) chaperone-mediated protein transport(GO:0072321) |
0.0 | 0.5 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.0 | 3.3 | GO:0055072 | iron ion homeostasis(GO:0055072) |
0.0 | 0.8 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
0.0 | 2.0 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
0.0 | 0.4 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.1 | GO:0045414 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) regulation of interleukin-8 biosynthetic process(GO:0045414) |
0.0 | 1.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.5 | GO:0070986 | left/right axis specification(GO:0070986) |
0.0 | 1.0 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 1.0 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.0 | 0.6 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
0.0 | 1.0 | GO:0042026 | protein refolding(GO:0042026) |
0.0 | 0.6 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.0 | 0.3 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
0.0 | 0.3 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.0 | 0.1 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
0.0 | 0.5 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.8 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
0.0 | 2.1 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 1.9 | GO:0045055 | regulated exocytosis(GO:0045055) |
0.0 | 0.4 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
0.0 | 0.1 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
0.0 | 0.2 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
0.0 | 0.7 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
0.0 | 0.4 | GO:0002446 | neutrophil mediated immunity(GO:0002446) |
0.0 | 2.3 | GO:0006906 | vesicle fusion(GO:0006906) organelle membrane fusion(GO:0090174) |
0.0 | 0.5 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
0.0 | 0.2 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.0 | 0.4 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.0 | 1.0 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
0.0 | 0.9 | GO:0007286 | spermatid development(GO:0007286) |
0.0 | 6.8 | GO:0006914 | autophagy(GO:0006914) |
0.0 | 0.3 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 0.6 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 1.3 | GO:0030641 | regulation of cellular pH(GO:0030641) |
0.0 | 0.2 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.0 | 0.2 | GO:0007296 | vitellogenesis(GO:0007296) |
0.0 | 2.2 | GO:0098656 | anion transmembrane transport(GO:0098656) |
0.0 | 0.3 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
0.0 | 0.1 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.0 | 0.4 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.0 | 0.6 | GO:0030199 | collagen fibril organization(GO:0030199) |
0.0 | 1.5 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
0.0 | 2.8 | GO:0051607 | defense response to virus(GO:0051607) |
0.0 | 0.1 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
0.0 | 0.1 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.0 | 0.1 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
0.0 | 0.8 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.5 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.4 | GO:0006089 | lactate metabolic process(GO:0006089) |
0.0 | 0.6 | GO:0001756 | somitogenesis(GO:0001756) |
0.0 | 0.3 | GO:0033622 | integrin activation(GO:0033622) |
0.0 | 0.1 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
0.0 | 0.2 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.1 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
0.0 | 0.0 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 0.2 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
0.0 | 0.5 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
0.0 | 1.1 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.0 | 0.1 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.0 | 0.7 | GO:0006400 | tRNA modification(GO:0006400) |
0.0 | 2.0 | GO:0043087 | regulation of GTPase activity(GO:0043087) |
0.0 | 0.2 | GO:0007143 | female meiotic division(GO:0007143) |
0.0 | 0.3 | GO:0050919 | negative chemotaxis(GO:0050919) |
0.0 | 0.1 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
0.0 | 0.3 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.8 | 14.3 | GO:0098855 | HCN channel complex(GO:0098855) |
3.3 | 9.9 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
2.5 | 7.5 | GO:0072534 | perineuronal net(GO:0072534) |
1.7 | 8.4 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
1.5 | 4.4 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
1.4 | 4.2 | GO:1903095 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
1.3 | 6.6 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
1.2 | 6.2 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
1.2 | 5.8 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
1.2 | 6.9 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
1.1 | 3.2 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
1.0 | 5.0 | GO:0032437 | cuticular plate(GO:0032437) |
0.9 | 17.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.9 | 0.9 | GO:0030128 | clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669) |
0.9 | 3.5 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
0.8 | 8.2 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.8 | 3.3 | GO:0031673 | H zone(GO:0031673) |
0.8 | 4.8 | GO:0097513 | myosin II filament(GO:0097513) |
0.8 | 3.9 | GO:0001533 | cornified envelope(GO:0001533) |
0.8 | 6.2 | GO:0033391 | chromatoid body(GO:0033391) |
0.7 | 9.7 | GO:0070852 | cell body fiber(GO:0070852) |
0.7 | 5.4 | GO:0097433 | dense body(GO:0097433) |
0.6 | 9.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.6 | 7.8 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.6 | 9.5 | GO:1990635 | proximal dendrite(GO:1990635) |
0.6 | 5.7 | GO:0032009 | early phagosome(GO:0032009) |
0.6 | 17.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.5 | 3.6 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.5 | 19.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.5 | 2.8 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.4 | 1.3 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.4 | 0.9 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
0.4 | 4.2 | GO:0030057 | desmosome(GO:0030057) |
0.4 | 4.1 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.4 | 6.1 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.4 | 2.8 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.4 | 2.0 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
0.4 | 5.5 | GO:0000145 | exocyst(GO:0000145) |
0.4 | 25.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.4 | 0.7 | GO:0098888 | extrinsic component of presynaptic membrane(GO:0098888) |
0.4 | 15.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.4 | 1.8 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.4 | 12.2 | GO:0051233 | spindle midzone(GO:0051233) |
0.4 | 1.1 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
0.4 | 3.3 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.4 | 1.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.4 | 0.7 | GO:0044308 | axonal spine(GO:0044308) |
0.4 | 1.1 | GO:0098835 | presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
0.3 | 1.7 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.3 | 2.3 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
0.3 | 6.7 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.3 | 1.4 | GO:0030891 | VCB complex(GO:0030891) |
0.3 | 17.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.3 | 3.0 | GO:0030427 | site of polarized growth(GO:0030427) |
0.3 | 2.4 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.3 | 2.1 | GO:0097427 | microtubule bundle(GO:0097427) |
0.3 | 3.4 | GO:0031209 | SCAR complex(GO:0031209) |
0.3 | 0.8 | GO:0034657 | GID complex(GO:0034657) |
0.3 | 4.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.2 | 1.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.2 | 9.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.2 | 1.2 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.2 | 0.2 | GO:1904949 | ATPase complex(GO:1904949) |
0.2 | 3.1 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.2 | 1.4 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.2 | 1.4 | GO:0005883 | neurofilament(GO:0005883) |
0.2 | 11.4 | GO:0031901 | early endosome membrane(GO:0031901) |
0.2 | 1.4 | GO:0000322 | storage vacuole(GO:0000322) |
0.2 | 2.1 | GO:0030478 | actin cap(GO:0030478) |
0.2 | 0.5 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.2 | 2.0 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.2 | 0.9 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
0.2 | 1.1 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.2 | 2.4 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.2 | 3.3 | GO:0031932 | TORC2 complex(GO:0031932) |
0.2 | 2.8 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.2 | 1.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.2 | 3.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.2 | 56.9 | GO:0060076 | excitatory synapse(GO:0060076) |
0.2 | 3.5 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
0.2 | 1.6 | GO:0032300 | mismatch repair complex(GO:0032300) |
0.2 | 5.1 | GO:0031201 | SNARE complex(GO:0031201) |
0.2 | 1.2 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.2 | 0.9 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.2 | 3.5 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.2 | 7.2 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.2 | 36.5 | GO:0000139 | Golgi membrane(GO:0000139) |
0.2 | 8.6 | GO:0005876 | spindle microtubule(GO:0005876) |
0.2 | 2.4 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
0.2 | 1.4 | GO:0042587 | glycogen granule(GO:0042587) |
0.2 | 1.5 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.1 | 0.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.1 | 1.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.1 | 1.4 | GO:0005915 | zonula adherens(GO:0005915) |
0.1 | 10.5 | GO:0034702 | ion channel complex(GO:0034702) |
0.1 | 3.2 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.1 | 3.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.1 | 0.4 | GO:0055087 | Ski complex(GO:0055087) |
0.1 | 1.4 | GO:0043296 | apical junction complex(GO:0043296) |
0.1 | 1.7 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 0.7 | GO:0070847 | core mediator complex(GO:0070847) |
0.1 | 4.2 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.1 | 1.9 | GO:0036038 | MKS complex(GO:0036038) |
0.1 | 0.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.1 | 2.8 | GO:0035869 | ciliary transition zone(GO:0035869) |
0.1 | 1.7 | GO:0043679 | axon terminus(GO:0043679) |
0.1 | 0.4 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 1.4 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 1.3 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.1 | 0.4 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
0.1 | 0.6 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 0.5 | GO:0005683 | U7 snRNP(GO:0005683) |
0.1 | 1.7 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.1 | 3.3 | GO:0032420 | stereocilium(GO:0032420) |
0.1 | 0.5 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.1 | 1.1 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) COPII vesicle coat(GO:0030127) |
0.1 | 1.3 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.1 | 1.1 | GO:0044754 | secondary lysosome(GO:0005767) autolysosome(GO:0044754) |
0.1 | 0.5 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.1 | 1.7 | GO:0035102 | PRC1 complex(GO:0035102) |
0.1 | 2.4 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
0.1 | 37.3 | GO:0030425 | dendrite(GO:0030425) |
0.1 | 1.4 | GO:0030027 | lamellipodium(GO:0030027) |
0.1 | 1.6 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.1 | 5.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.1 | 5.2 | GO:0005811 | lipid particle(GO:0005811) |
0.1 | 1.4 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
0.1 | 0.5 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
0.1 | 0.7 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
0.1 | 0.3 | GO:0033263 | CORVET complex(GO:0033263) |
0.1 | 0.3 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 1.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 0.5 | GO:0033061 | DNA recombinase mediator complex(GO:0033061) |
0.1 | 2.1 | GO:0036477 | somatodendritic compartment(GO:0036477) |
0.1 | 5.9 | GO:0005604 | basement membrane(GO:0005604) |
0.1 | 1.4 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 0.5 | GO:0031415 | NatA complex(GO:0031415) |
0.1 | 0.5 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.1 | 1.1 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.1 | 4.3 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 8.5 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
0.1 | 0.4 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 0.3 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.1 | 1.1 | GO:0032040 | small-subunit processome(GO:0032040) |
0.1 | 0.3 | GO:0030870 | Mre11 complex(GO:0030870) |
0.1 | 3.8 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
0.1 | 3.3 | GO:0005769 | early endosome(GO:0005769) |
0.1 | 0.3 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 1.4 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.1 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
0.0 | 9.2 | GO:0045202 | synapse(GO:0045202) |
0.0 | 1.5 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
0.0 | 1.0 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 0.3 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 1.6 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 3.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.2 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
0.0 | 0.5 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.0 | 4.2 | GO:0070382 | exocytic vesicle(GO:0070382) |
0.0 | 0.6 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 0.9 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 0.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 1.8 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 1.2 | GO:0036126 | sperm flagellum(GO:0036126) |
0.0 | 0.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 1.5 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.1 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.0 | 0.6 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) FHF complex(GO:0070695) |
0.0 | 0.8 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.4 | GO:0042641 | actomyosin(GO:0042641) |
0.0 | 0.9 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 1.3 | GO:0005903 | brush border(GO:0005903) |
0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.4 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.5 | GO:0030686 | 90S preribosome(GO:0030686) |
0.0 | 2.9 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 1.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.5 | GO:0031514 | motile cilium(GO:0031514) |
0.0 | 0.6 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 1.5 | GO:0009986 | cell surface(GO:0009986) |
0.0 | 3.9 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.0 | 1.9 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 0.2 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 45.5 | GO:0016021 | integral component of membrane(GO:0016021) |
0.0 | 0.3 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.1 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.0 | 0.1 | GO:0000812 | Swr1 complex(GO:0000812) |
0.0 | 0.1 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.6 | GO:0030016 | myofibril(GO:0030016) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.7 | 18.6 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
3.6 | 14.3 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
3.1 | 18.7 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
2.5 | 15.0 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
2.3 | 6.9 | GO:0016015 | morphogen activity(GO:0016015) |
2.1 | 6.4 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
1.9 | 11.5 | GO:0005042 | netrin receptor activity(GO:0005042) |
1.8 | 5.5 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
1.8 | 12.8 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
1.6 | 12.6 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
1.5 | 8.7 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
1.5 | 5.8 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
1.4 | 8.4 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
1.3 | 12.0 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
1.3 | 6.6 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
1.3 | 3.8 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
1.3 | 5.1 | GO:0001847 | opsonin receptor activity(GO:0001847) |
1.2 | 8.3 | GO:0032184 | SUMO polymer binding(GO:0032184) |
1.1 | 16.7 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
1.1 | 3.3 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
1.1 | 4.4 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
1.1 | 3.2 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
1.1 | 2.1 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
1.1 | 3.2 | GO:0051379 | epinephrine binding(GO:0051379) |
1.0 | 8.2 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
1.0 | 3.0 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
1.0 | 3.0 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
1.0 | 2.9 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
1.0 | 2.9 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
0.9 | 6.5 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.9 | 2.8 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
0.9 | 4.6 | GO:2001070 | starch binding(GO:2001070) |
0.9 | 3.6 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.9 | 2.7 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
0.9 | 4.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.9 | 6.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.9 | 2.6 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
0.8 | 18.5 | GO:0043274 | phospholipase binding(GO:0043274) |
0.8 | 4.2 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
0.8 | 3.3 | GO:0047237 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) |
0.8 | 2.4 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.8 | 11.1 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
0.8 | 8.4 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.8 | 2.3 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.7 | 6.1 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.7 | 6.1 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.7 | 5.4 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
0.7 | 2.7 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.7 | 2.6 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.7 | 2.0 | GO:0032052 | bile acid binding(GO:0032052) |
0.6 | 11.7 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.6 | 6.3 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.6 | 1.8 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.6 | 3.0 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
0.6 | 2.9 | GO:0035174 | histone serine kinase activity(GO:0035174) |
0.6 | 6.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.6 | 2.8 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
0.6 | 1.7 | GO:0071209 | U7 snRNA binding(GO:0071209) |
0.6 | 24.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.6 | 2.8 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
0.6 | 2.2 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.5 | 4.4 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.5 | 1.6 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142) |
0.5 | 2.7 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
0.5 | 2.7 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
0.5 | 2.5 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
0.5 | 7.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.5 | 7.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.5 | 1.5 | GO:1901618 | organic hydroxy compound transmembrane transporter activity(GO:1901618) |
0.5 | 2.4 | GO:0048495 | Roundabout binding(GO:0048495) |
0.5 | 7.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.5 | 4.8 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.5 | 3.8 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
0.5 | 4.2 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.5 | 2.8 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.5 | 6.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.5 | 4.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.4 | 8.0 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.4 | 3.4 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
0.4 | 1.7 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
0.4 | 1.7 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
0.4 | 3.8 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.4 | 3.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.4 | 2.0 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
0.4 | 5.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.4 | 1.6 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
0.4 | 5.7 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.4 | 2.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.4 | 8.2 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.4 | 12.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.4 | 8.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.4 | 3.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.4 | 7.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.4 | 2.2 | GO:0097001 | ceramide binding(GO:0097001) |
0.4 | 1.5 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.4 | 1.5 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.4 | 2.9 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.4 | 4.7 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.4 | 2.1 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.4 | 1.4 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.4 | 3.2 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
0.3 | 4.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.3 | 2.0 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.3 | 9.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.3 | 7.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.3 | 9.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.3 | 1.9 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
0.3 | 5.0 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.3 | 1.9 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.3 | 2.1 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
0.3 | 0.6 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
0.3 | 1.1 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
0.3 | 1.4 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
0.3 | 3.7 | GO:0031005 | filamin binding(GO:0031005) |
0.3 | 1.1 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.3 | 1.4 | GO:0070330 | aromatase activity(GO:0070330) |
0.3 | 2.0 | GO:0036122 | BMP binding(GO:0036122) |
0.3 | 6.7 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.3 | 2.5 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.3 | 0.8 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.3 | 0.8 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
0.3 | 8.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.3 | 2.9 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.3 | 1.1 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.3 | 1.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.3 | 0.8 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
0.3 | 0.5 | GO:0038132 | neuregulin binding(GO:0038132) |
0.3 | 2.8 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.2 | 2.0 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.2 | 1.7 | GO:0030911 | TPR domain binding(GO:0030911) |
0.2 | 1.7 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.2 | 0.5 | GO:0016247 | channel regulator activity(GO:0016247) |
0.2 | 0.7 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.2 | 0.7 | GO:0015232 | heme transporter activity(GO:0015232) |
0.2 | 0.7 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
0.2 | 1.9 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
0.2 | 3.1 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.2 | 2.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.2 | 1.4 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.2 | 1.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.2 | 2.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.2 | 0.9 | GO:0036033 | mediator complex binding(GO:0036033) |
0.2 | 6.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.2 | 2.2 | GO:0004890 | GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917) |
0.2 | 0.9 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
0.2 | 0.6 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
0.2 | 1.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.2 | 2.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.2 | 1.9 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.2 | 2.1 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
0.2 | 1.5 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
0.2 | 0.6 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
0.2 | 7.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.2 | 3.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.2 | 1.0 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.2 | 1.8 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
0.2 | 0.8 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.2 | 7.4 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.2 | 7.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.2 | 1.1 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.2 | 16.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.2 | 0.6 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.2 | 1.3 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
0.2 | 0.7 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
0.2 | 0.5 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
0.2 | 1.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.2 | 0.7 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
0.2 | 0.7 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.2 | 0.5 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
0.2 | 0.9 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
0.2 | 0.7 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.2 | 0.7 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.2 | 0.5 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
0.2 | 1.7 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.2 | 2.3 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
0.1 | 4.0 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 0.9 | GO:0008227 | G-protein coupled amine receptor activity(GO:0008227) |
0.1 | 0.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
0.1 | 0.4 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751) |
0.1 | 6.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 0.7 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 5.4 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.1 | 0.8 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.1 | 3.0 | GO:0042287 | MHC protein binding(GO:0042287) |
0.1 | 0.7 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.1 | 2.6 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.1 | 3.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.1 | 5.9 | GO:0015485 | cholesterol binding(GO:0015485) |
0.1 | 0.5 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
0.1 | 1.1 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
0.1 | 1.9 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.1 | 3.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.1 | 0.8 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
0.1 | 2.4 | GO:0032183 | SUMO binding(GO:0032183) |
0.1 | 0.4 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
0.1 | 0.6 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.1 | 0.6 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.1 | 2.2 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.1 | 1.6 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.1 | 0.9 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 2.3 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 0.5 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
0.1 | 0.4 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.1 | 1.1 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 0.8 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.1 | 0.8 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.1 | 0.8 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.1 | 0.4 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
0.1 | 2.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 1.1 | GO:0004659 | prenyltransferase activity(GO:0004659) |
0.1 | 0.3 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.1 | 0.8 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.1 | 1.7 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.1 | 1.5 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.1 | 2.0 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.1 | 0.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.1 | 0.3 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.1 | 3.2 | GO:0043175 | RNA polymerase core enzyme binding(GO:0043175) |
0.1 | 0.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 0.6 | GO:0097016 | L27 domain binding(GO:0097016) |
0.1 | 0.6 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 10.0 | GO:0005516 | calmodulin binding(GO:0005516) |
0.1 | 0.4 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.1 | 1.6 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.1 | 1.3 | GO:0070063 | RNA polymerase binding(GO:0070063) |
0.1 | 2.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 0.6 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.1 | 3.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.1 | 0.4 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
0.1 | 1.4 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.1 | 3.8 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.1 | 0.9 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.1 | 1.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 3.7 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.1 | 2.1 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.1 | 0.4 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
0.1 | 0.5 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.1 | 0.6 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.1 | 0.2 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
0.1 | 20.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.1 | 0.3 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.1 | 1.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 0.4 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
0.1 | 0.3 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
0.1 | 1.6 | GO:0019209 | kinase activator activity(GO:0019209) |
0.1 | 1.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 1.1 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.1 | 1.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 2.9 | GO:0000049 | tRNA binding(GO:0000049) |
0.1 | 1.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.1 | 1.1 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.1 | 0.3 | GO:0034452 | dynactin binding(GO:0034452) |
0.1 | 4.3 | GO:0072509 | divalent inorganic cation transmembrane transporter activity(GO:0072509) |
0.1 | 2.4 | GO:0019955 | cytokine binding(GO:0019955) |
0.1 | 2.9 | GO:0097110 | scaffold protein binding(GO:0097110) |
0.1 | 0.9 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 2.3 | GO:0019894 | kinesin binding(GO:0019894) |
0.1 | 1.1 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.3 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
0.0 | 0.6 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.5 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
0.0 | 0.4 | GO:0000182 | rDNA binding(GO:0000182) |
0.0 | 0.9 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 0.2 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
0.0 | 0.3 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
0.0 | 0.3 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
0.0 | 0.3 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
0.0 | 0.3 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 2.5 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 1.0 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.0 | 1.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 9.3 | GO:0003924 | GTPase activity(GO:0003924) |
0.0 | 1.8 | GO:0043022 | ribosome binding(GO:0043022) |
0.0 | 0.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.3 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
0.0 | 1.1 | GO:0035254 | glutamate receptor binding(GO:0035254) |
0.0 | 0.5 | GO:0030275 | LRR domain binding(GO:0030275) |
0.0 | 3.3 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
0.0 | 0.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.1 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.0 | 0.7 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 0.3 | GO:0015929 | hexosaminidase activity(GO:0015929) |
0.0 | 0.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.2 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
0.0 | 0.2 | GO:0070492 | oligosaccharide binding(GO:0070492) |
0.0 | 0.3 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.4 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
0.0 | 2.0 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.5 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.3 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.0 | 0.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
0.0 | 0.5 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.0 | 0.8 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 0.1 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
0.0 | 0.1 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.0 | 0.1 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 1.2 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.3 | GO:0017046 | peptide hormone binding(GO:0017046) |
0.0 | 0.3 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
0.0 | 0.2 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
0.0 | 0.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.0 | 0.5 | GO:0019905 | syntaxin binding(GO:0019905) |
0.0 | 3.8 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 0.2 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
0.0 | 0.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.3 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.3 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.2 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.0 | 1.5 | GO:0000287 | magnesium ion binding(GO:0000287) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 5.5 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
1.2 | 20.4 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.8 | 18.7 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.6 | 2.5 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.5 | 0.5 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.5 | 20.3 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.4 | 15.4 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.3 | 10.4 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.3 | 5.8 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.3 | 6.3 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.3 | 1.3 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.3 | 4.5 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.2 | 5.2 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
0.2 | 1.5 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.2 | 5.4 | PID_ARF_3PATHWAY | Arf1 pathway |
0.2 | 14.1 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.2 | 3.6 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.2 | 8.8 | PID_SHP2_PATHWAY | SHP2 signaling |
0.2 | 6.7 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.2 | 1.4 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.2 | 6.9 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.2 | 3.1 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
0.2 | 2.8 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
0.2 | 1.9 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.2 | 2.3 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.2 | 5.6 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.2 | 6.1 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.2 | 1.8 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.2 | 0.6 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
0.2 | 2.4 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.1 | 2.8 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.1 | 4.1 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.1 | 4.5 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
0.1 | 1.2 | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | EGF receptor (ErbB1) signaling pathway |
0.1 | 1.3 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
0.1 | 0.8 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.1 | 3.5 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.1 | 0.7 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
0.1 | 13.2 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.1 | 2.9 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.1 | 1.2 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
0.1 | 0.4 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
0.1 | 4.6 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.1 | 6.5 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.1 | 3.6 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.1 | 1.3 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.1 | 3.7 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
0.1 | 0.9 | SIG_BCR_SIGNALING_PATHWAY | Members of the BCR signaling pathway |
0.1 | 0.5 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.1 | 8.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 1.4 | PID_FGF_PATHWAY | FGF signaling pathway |
0.1 | 1.3 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.1 | 0.8 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
0.1 | 0.6 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.1 | 0.9 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
0.1 | 1.8 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.0 | 0.5 | PID_VEGFR1_PATHWAY | VEGFR1 specific signals |
0.0 | 1.1 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 1.8 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.0 | 6.5 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.0 | 0.7 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 1.2 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 0.6 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
0.0 | 0.4 | PID_IL1_PATHWAY | IL1-mediated signaling events |
0.0 | 0.2 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.0 | 1.1 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.3 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.2 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.0 | 0.3 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 0.2 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 0.3 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.0 | 0.3 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 0.5 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 0.1 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 17.2 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.9 | 2.7 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
0.8 | 5.6 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.7 | 7.1 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.7 | 5.7 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.7 | 12.7 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
0.7 | 7.3 | REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
0.7 | 26.2 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.6 | 8.4 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.6 | 17.2 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.5 | 18.1 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.5 | 12.5 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.5 | 4.7 | REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
0.5 | 1.5 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.5 | 16.4 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.4 | 10.2 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.4 | 1.8 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | Genes involved in Signaling by EGFR in Cancer |
0.4 | 11.2 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.4 | 4.6 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.4 | 11.5 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.4 | 38.3 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
0.4 | 15.7 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.4 | 0.4 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.3 | 4.7 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.3 | 10.9 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.3 | 4.3 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.3 | 9.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.3 | 4.1 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.3 | 12.1 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.3 | 4.9 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.3 | 3.6 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.3 | 0.8 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.3 | 6.6 | REACTOME_IL_RECEPTOR_SHC_SIGNALING | Genes involved in Interleukin receptor SHC signaling |
0.3 | 1.6 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.3 | 2.3 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.2 | 1.7 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.2 | 5.6 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.2 | 1.2 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.2 | 4.6 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
0.2 | 1.8 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
0.2 | 8.2 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.2 | 2.7 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.2 | 1.7 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
0.2 | 4.0 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.2 | 5.0 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
0.2 | 4.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.2 | 5.7 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.2 | 2.9 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.2 | 1.1 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.2 | 0.8 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.2 | 8.6 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.2 | 1.9 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.2 | 1.8 | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
0.2 | 4.7 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.2 | 2.0 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.2 | 2.2 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.2 | 1.5 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.2 | 1.0 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.2 | 5.9 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.2 | 4.5 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.2 | 2.1 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.2 | 1.6 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.2 | 4.4 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.1 | 3.2 | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
0.1 | 3.3 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.1 | 3.1 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.1 | 1.3 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.1 | 1.6 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.1 | 20.8 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 3.1 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
0.1 | 0.8 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.1 | 0.4 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
0.1 | 1.2 | REACTOME_IRON_UPTAKE_AND_TRANSPORT | Genes involved in Iron uptake and transport |
0.1 | 9.6 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.1 | 0.9 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
0.1 | 2.2 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.1 | 0.9 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
0.1 | 1.3 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.1 | 0.2 | REACTOME_FRS2_MEDIATED_CASCADE | Genes involved in FRS2-mediated cascade |
0.1 | 2.3 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.1 | 0.8 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
0.1 | 0.7 | REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS | Genes involved in Glucagon-type ligand receptors |
0.1 | 2.3 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.1 | 2.0 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.1 | 0.8 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.1 | 0.6 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.1 | 0.6 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
0.1 | 0.7 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
0.1 | 2.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.1 | 2.1 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
0.1 | 0.3 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.1 | 3.0 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.1 | 3.5 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.1 | 0.4 | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK |
0.1 | 0.3 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 0.2 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 1.4 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 0.5 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.0 | 1.8 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 2.3 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 0.6 | REACTOME_DOWNSTREAM_TCR_SIGNALING | Genes involved in Downstream TCR signaling |
0.0 | 0.8 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.5 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.6 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 1.4 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
0.0 | 1.1 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.5 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
0.0 | 0.4 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.4 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 0.7 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 0.7 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 3.3 | REACTOME_MRNA_PROCESSING | Genes involved in mRNA Processing |
0.0 | 0.2 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 1.3 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |