Motif ID: Hmga2

Z-value: 1.364


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_1204765270.019.1e-01Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_19418930 36.517 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_3013140 36.296 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr2_-_98667264 36.178 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr9_+_3004457 30.254 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr9_+_3023547 24.784 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3025417 24.577 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr9_+_3018753 22.424 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr9_+_3017408 21.106 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr11_-_102897123 4.501 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr7_-_5413145 4.043 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr14_-_100149764 3.549 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr3_+_53845086 3.547 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr1_+_172698046 3.490 ENSMUST00000038495.3
Crp
C-reactive protein, pentraxin-related
chr11_-_102897146 3.387 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr4_+_44756609 3.255 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chr4_+_44756553 3.161 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr13_-_62371936 3.108 ENSMUST00000107989.3
Gm3604
predicted gene 3604
chr19_+_12573508 2.903 ENSMUST00000025595.4
Fam111a
family with sequence similarity 111, member A
chr16_-_43979050 2.901 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr1_+_136676413 2.661 ENSMUST00000181491.1
Gm19705
predicted gene, 19705
chr5_+_14514918 2.612 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr2_+_158375638 2.541 ENSMUST00000109488.1
Snhg11
small nucleolar RNA host gene 11
chrX_-_164980310 2.324 ENSMUST00000004715.1
ENSMUST00000112248.2
Mospd2

motile sperm domain containing 2

chr12_-_23780265 2.289 ENSMUST00000072014.4
Gm10330
predicted gene 10330
chr4_+_103114712 2.171 ENSMUST00000143417.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chrM_+_10167 2.052 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chrM_+_9870 1.993 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr14_-_36919513 1.939 ENSMUST00000182042.1
Ccser2
coiled-coil serine rich 2
chr2_+_62664279 1.937 ENSMUST00000028257.2
Gca
grancalcin
chrX_+_103356464 1.915 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr16_-_36784784 1.865 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr1_+_46066738 1.852 ENSMUST00000069293.7
Dnah7b
dynein, axonemal, heavy chain 7B
chr9_-_8134294 1.847 ENSMUST00000037397.6
AK129341
cDNA sequence AK129341
chr14_-_36919314 1.846 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr10_+_58446845 1.769 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chr5_-_106926245 1.762 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr4_+_110397661 1.758 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr13_-_62607499 1.757 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr2_+_5951440 1.692 ENSMUST00000060092.6
Upf2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr5_-_96164147 1.665 ENSMUST00000137207.1
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr17_-_35000848 1.613 ENSMUST00000166828.3
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr11_+_75999912 1.541 ENSMUST00000066408.5
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chr9_+_92309362 1.513 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr3_+_135485605 1.503 ENSMUST00000029814.9
Manba
mannosidase, beta A, lysosomal
chr4_-_32923455 1.456 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr1_-_24612700 1.437 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr10_+_69787431 1.414 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr12_+_84285232 1.369 ENSMUST00000123614.1
ENSMUST00000147363.1
ENSMUST00000135001.1
ENSMUST00000146377.1
Ptgr2



prostaglandin reductase 2



chr9_+_13619990 1.363 ENSMUST00000159294.1
Maml2
mastermind like 2 (Drosophila)
chr7_-_12422488 1.356 ENSMUST00000120220.1
Zfp551
zinc fingr protein 551
chr1_+_132008285 1.326 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chrX_-_16817339 1.227 ENSMUST00000040820.6
Maob
monoamine oxidase B
chr18_+_37447641 1.207 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr11_+_77462325 1.185 ENSMUST00000102493.1
Coro6
coronin 6
chr10_-_117282262 1.168 ENSMUST00000092163.7
Lyz2
lysozyme 2
chr16_+_87454976 1.099 ENSMUST00000119504.1
ENSMUST00000131356.1
Usp16

ubiquitin specific peptidase 16

chr2_-_102901346 1.072 ENSMUST00000111192.2
ENSMUST00000111190.2
ENSMUST00000111198.2
ENSMUST00000111191.2
ENSMUST00000060516.7
ENSMUST00000099673.2
ENSMUST00000005218.8
ENSMUST00000111194.1
Cd44







CD44 antigen







chrX_+_37126777 1.050 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr13_-_74482943 1.045 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr9_-_97111117 1.012 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36
chr7_-_42642547 1.002 ENSMUST00000098503.2
9830147E19Rik
RIKEN cDNA 9830147E19 gene
chr7_+_7171330 0.953 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr7_-_12422751 0.942 ENSMUST00000080348.5
Zfp551
zinc fingr protein 551
chr4_+_57637816 0.927 ENSMUST00000150412.1
Gm20459
predicted gene 20459
chr13_+_21722057 0.922 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr9_+_88581036 0.892 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chr6_+_21949571 0.855 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3


inhibitor of growth family, member 3


chr11_-_83302586 0.848 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr1_-_144004142 0.802 ENSMUST00000127206.1
Rgs2
regulator of G-protein signaling 2
chr1_+_93235836 0.798 ENSMUST00000062202.7
Sned1
sushi, nidogen and EGF-like domains 1
chr17_-_74459096 0.795 ENSMUST00000052124.7
Nlrc4
NLR family, CARD domain containing 4
chr16_+_96361749 0.778 ENSMUST00000000163.6
ENSMUST00000081093.3
ENSMUST00000113795.1
Igsf5


immunoglobulin superfamily, member 5


chr2_-_18048784 0.738 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr17_+_40811089 0.731 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr7_-_46672537 0.729 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr16_-_36784924 0.698 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr1_+_66386968 0.681 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr2_+_29124106 0.666 ENSMUST00000129544.1
Setx
senataxin
chr11_+_22971991 0.607 ENSMUST00000049506.5
Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr7_+_45526330 0.594 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr11_+_82035569 0.589 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr18_+_37411674 0.579 ENSMUST00000051126.2
Pcdhb10
protocadherin beta 10
chr1_-_74588117 0.559 ENSMUST00000066986.6
Zfp142
zinc finger protein 142
chr17_+_73107982 0.514 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
Lclat1


lysocardiolipin acyltransferase 1


chr4_+_126286792 0.509 ENSMUST00000070132.6
Col8a2
collagen, type VIII, alpha 2
chr14_-_62456286 0.505 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr2_+_19344317 0.482 ENSMUST00000141289.1
4930447M23Rik
RIKEN cDNA 4930447M23 gene
chr16_+_33185045 0.429 ENSMUST00000039733.8
Osbpl11
oxysterol binding protein-like 11
chr9_+_122351555 0.404 ENSMUST00000156520.1
Abhd5
abhydrolase domain containing 5
chr17_-_35000746 0.394 ENSMUST00000163360.1
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr13_+_104178797 0.382 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chrX_+_164980592 0.368 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fancb


Fanconi anemia, complementation group B


chr17_-_6961156 0.351 ENSMUST00000063683.6
Tagap1
T cell activation GTPase activating protein 1
chr11_+_105178765 0.320 ENSMUST00000106939.2
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr5_+_21372642 0.308 ENSMUST00000035799.5
Fgl2
fibrinogen-like protein 2
chr6_+_128644838 0.294 ENSMUST00000036712.4
Gm5884
predicted pseudogene 5884
chr10_+_90071095 0.259 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_+_83302817 0.242 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr14_+_25980039 0.224 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr16_+_32277449 0.218 ENSMUST00000155649.1
ENSMUST00000014218.8
ENSMUST00000171474.1
Rnf168


ring finger protein 168


chr9_+_122351723 0.168 ENSMUST00000111497.3
Abhd5
abhydrolase domain containing 5
chr14_+_52197502 0.168 ENSMUST00000180857.1
Gm26590
predicted gene, 26590
chr16_+_96235801 0.115 ENSMUST00000113800.2
B3galt5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr17_+_36958571 0.111 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr10_+_29313500 0.109 ENSMUST00000020034.4
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr3_-_152210032 0.101 ENSMUST00000144950.1
Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr10_+_94550852 0.087 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3

transmembrane and coiled coil domains 3

chr11_-_116307168 0.086 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr4_-_25281801 0.062 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr3_+_85574109 0.050 ENSMUST00000127348.1
ENSMUST00000107672.1
ENSMUST00000107674.1
Pet112


PET112 homolog (S. cerevisiae)


chr2_+_27676440 0.040 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.9 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.9 2.6 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.6 3.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.5 1.5 GO:0016598 protein arginylation(GO:0016598)
0.5 2.6 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.4 1.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.4 1.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 1.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.4 1.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 1.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.3 1.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.3 1.0 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.7 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 1.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 0.8 GO:0070269 pyroptosis(GO:0070269)
0.2 1.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 1.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 0.8 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.2 1.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 2.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 1.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:2000427 eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683) positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.4 GO:0010889 regulation of sequestering of triglyceride(GO:0010889)
0.1 1.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 2.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.7 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 1.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.7 GO:0031100 organ regeneration(GO:0031100)
0.1 2.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 3.7 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 1.4 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 4.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.0 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.7 2.6 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.6 1.9 GO:0036156 inner dynein arm(GO:0036156)
0.2 1.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.8 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 0.8 GO:0061702 inflammasome complex(GO:0061702)
0.2 0.6 GO:0044299 C-fiber(GO:0044299)
0.2 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.6 GO:0089701 U2AF(GO:0089701)
0.0 1.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.6 GO:0070469 respiratory chain(GO:0070469)
0.0 3.0 GO:0030175 filopodium(GO:0030175)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0042936 dipeptide transporter activity(GO:0042936)
0.5 3.5 GO:0001849 complement component C1q binding(GO:0001849)
0.5 1.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.4 1.2 GO:0003796 lysozyme activity(GO:0003796)
0.3 1.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 0.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 0.7 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 2.6 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 3.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 9.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.5 GO:0005537 mannose binding(GO:0005537)
0.1 2.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.7 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1 1.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.0 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.6 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 3.3 GO:0008017 microtubule binding(GO:0008017)
0.0 3.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.8 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.6 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 1.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.4 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.5 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 7.9 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.7 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.7 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 0.8 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.8 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 2.6 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.7 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway