Motif ID: Hoxa5
Z-value: 0.918
Transcription factors associated with Hoxa5:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxa5 | ENSMUSG00000038253.6 | Hoxa5 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 16.8 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.6 | 4.4 | GO:0044838 | cell quiescence(GO:0044838) |
| 0.6 | 1.9 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
| 0.6 | 2.5 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 0.6 | 2.9 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.5 | 2.1 | GO:0014042 | positive regulation of neuron maturation(GO:0014042) |
| 0.5 | 1.5 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
| 0.5 | 1.4 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
| 0.5 | 2.3 | GO:0021856 | cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) facioacoustic ganglion development(GO:1903375) |
| 0.5 | 2.3 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.4 | 3.6 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.4 | 1.3 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
| 0.4 | 3.0 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.4 | 0.8 | GO:1990705 | cholangiocyte proliferation(GO:1990705) |
| 0.4 | 1.2 | GO:1901079 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) |
| 0.4 | 1.2 | GO:0019343 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) |
| 0.3 | 2.0 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
| 0.3 | 1.9 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.3 | 2.4 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
| 0.3 | 0.6 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.3 | 0.8 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
| 0.3 | 1.4 | GO:0042891 | antibiotic transport(GO:0042891) dipeptide transport(GO:0042938) |
| 0.3 | 4.2 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.3 | 0.8 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
| 0.2 | 10.1 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.2 | 2.0 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.2 | 0.9 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
| 0.2 | 1.2 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.2 | 0.9 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.2 | 1.1 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.2 | 0.8 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 0.2 | 0.6 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.2 | 0.6 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 0.2 | 0.6 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.2 | 0.8 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.2 | 0.6 | GO:1902071 | positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
| 0.2 | 0.7 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.2 | 0.5 | GO:0051105 | regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) |
| 0.2 | 0.5 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 0.2 | 0.9 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.2 | 1.7 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.2 | 0.5 | GO:0008594 | photoreceptor cell morphogenesis(GO:0008594) |
| 0.2 | 0.5 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
| 0.2 | 1.3 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.2 | 1.1 | GO:0007418 | ventral midline development(GO:0007418) |
| 0.2 | 1.4 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.2 | 4.1 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.2 | 0.9 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.1 | 1.0 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.1 | 0.7 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 0.1 | 1.4 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.1 | 0.5 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 1.1 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 0.9 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
| 0.1 | 0.8 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 0.4 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.1 | 0.8 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.1 | 0.4 | GO:0019046 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
| 0.1 | 0.4 | GO:0043031 | negative regulation of macrophage activation(GO:0043031) |
| 0.1 | 0.5 | GO:0060295 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 0.1 | 0.9 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 0.1 | 0.7 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.7 | GO:0032196 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196) |
| 0.1 | 0.4 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 0.1 | 0.5 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 0.1 | 9.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 1.5 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.1 | 0.3 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.1 | 0.5 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.1 | 1.0 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.1 | 0.3 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 0.1 | 0.8 | GO:2000258 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.1 | 4.8 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.1 | 1.6 | GO:0007606 | sensory perception of chemical stimulus(GO:0007606) |
| 0.1 | 0.5 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.1 | 0.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.1 | 0.3 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.1 | 0.9 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.1 | 1.9 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.1 | 1.1 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.1 | 0.3 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 0.1 | 0.6 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.1 | 1.1 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.1 | 0.9 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.1 | 0.1 | GO:0042558 | pteridine-containing compound metabolic process(GO:0042558) pteridine-containing compound biosynthetic process(GO:0042559) |
| 0.1 | 1.5 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.1 | 1.0 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.4 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.1 | 0.5 | GO:0032096 | negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099) |
| 0.1 | 1.1 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.1 | 2.6 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 0.3 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) regulation of osteoclast proliferation(GO:0090289) |
| 0.1 | 0.8 | GO:0042435 | indole-containing compound biosynthetic process(GO:0042435) |
| 0.1 | 0.3 | GO:1903207 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 0.1 | 1.3 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.1 | 2.4 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.1 | 1.0 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.1 | 0.5 | GO:0035247 | peptidyl-arginine omega-N-methylation(GO:0035247) |
| 0.1 | 3.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.1 | 1.3 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 0.1 | 0.5 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 0.1 | GO:0061526 | acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) musculoskeletal movement, spinal reflex action(GO:0050883) acetylcholine secretion(GO:0061526) |
| 0.1 | 0.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.1 | 2.3 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.1 | 0.2 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.1 | 1.4 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.1 | 0.8 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.1 | 1.4 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 0.7 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 0.3 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 0.1 | 0.3 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.1 | 0.3 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.1 | 0.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 0.7 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
| 0.1 | 0.3 | GO:0007320 | insemination(GO:0007320) |
| 0.1 | 0.4 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
| 0.1 | 0.2 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 0.1 | 0.5 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.1 | 2.8 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 7.5 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.1 | 2.8 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 0.3 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.1 | 0.6 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.1 | 0.8 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 1.0 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.1 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 0.0 | 0.3 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.0 | 1.1 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 0.2 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 0.0 | 0.3 | GO:0031397 | negative regulation of protein ubiquitination(GO:0031397) |
| 0.0 | 0.4 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.0 | 0.9 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.0 | 0.3 | GO:0019673 | GDP-mannose metabolic process(GO:0019673) |
| 0.0 | 0.7 | GO:0045745 | positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745) |
| 0.0 | 1.1 | GO:0033622 | integrin activation(GO:0033622) |
| 0.0 | 1.2 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.6 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.0 | 0.6 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.5 | GO:0045836 | positive regulation of meiotic nuclear division(GO:0045836) |
| 0.0 | 0.1 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.0 | 0.3 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.0 | 0.7 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 1.0 | GO:0034113 | heterotypic cell-cell adhesion(GO:0034113) |
| 0.0 | 0.2 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.0 | 0.2 | GO:0001302 | replicative cell aging(GO:0001302) |
| 0.0 | 0.3 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.0 | 1.8 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.0 | 0.4 | GO:0046548 | retinal rod cell development(GO:0046548) |
| 0.0 | 0.9 | GO:2000279 | negative regulation of DNA biosynthetic process(GO:2000279) |
| 0.0 | 0.3 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
| 0.0 | 0.4 | GO:0045019 | negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406) |
| 0.0 | 0.7 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.0 | 0.4 | GO:0045624 | positive regulation of T-helper cell differentiation(GO:0045624) |
| 0.0 | 0.2 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.0 | 0.2 | GO:0014054 | positive regulation of gamma-aminobutyric acid secretion(GO:0014054) |
| 0.0 | 1.2 | GO:0042246 | tissue regeneration(GO:0042246) |
| 0.0 | 0.6 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.0 | 0.6 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
| 0.0 | 0.2 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
| 0.0 | 0.3 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.0 | 1.0 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.0 | 0.3 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.5 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.0 | 0.1 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417) |
| 0.0 | 0.2 | GO:0051204 | protein insertion into mitochondrial membrane(GO:0051204) |
| 0.0 | 0.2 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.0 | 0.1 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 0.0 | 0.2 | GO:1903748 | negative regulation of establishment of protein localization to mitochondrion(GO:1903748) |
| 0.0 | 0.4 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.5 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.0 | 0.5 | GO:0051898 | negative regulation of protein kinase B signaling(GO:0051898) |
| 0.0 | 0.2 | GO:0098535 | positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535) |
| 0.0 | 0.1 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) |
| 0.0 | 0.1 | GO:0019732 | antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760) regulation of defense response to fungus(GO:1900150) regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035) |
| 0.0 | 0.5 | GO:0036344 | platelet morphogenesis(GO:0036344) |
| 0.0 | 0.3 | GO:0016246 | RNA interference(GO:0016246) |
| 0.0 | 1.4 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 0.0 | 0.6 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.0 | 0.3 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.0 | 0.2 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.0 | 0.4 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.1 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.0 | 0.0 | GO:0032661 | regulation of interleukin-18 production(GO:0032661) negative regulation of interleukin-18 production(GO:0032701) |
| 0.0 | 0.2 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.0 | 0.2 | GO:0097369 | sodium ion import(GO:0097369) |
| 0.0 | 0.5 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
| 0.0 | 0.1 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.0 | 0.1 | GO:0099645 | modification of postsynaptic actin cytoskeleton(GO:0098885) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645) |
| 0.0 | 0.3 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.5 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.0 | 0.4 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.6 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 0.3 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
| 0.0 | 0.6 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.0 | 0.6 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.5 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
| 0.0 | 0.7 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.0 | 0.1 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.0 | 0.2 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
| 0.0 | 1.5 | GO:0009566 | fertilization(GO:0009566) |
| 0.0 | 0.4 | GO:0001523 | retinoid metabolic process(GO:0001523) |
| 0.0 | 0.3 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 0.2 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.3 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 2.3 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 0.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.3 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.0 | 0.2 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.3 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 0.3 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 0.9 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.0 | 1.0 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 0.0 | 0.4 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 0.0 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.0 | 0.3 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.6 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity(GO:0032088) |
| 0.0 | 0.1 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.4 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.6 | 2.3 | GO:0097487 | vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487) |
| 0.4 | 2.1 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.4 | 2.5 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.4 | 1.5 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.3 | 1.0 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.3 | 1.2 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.3 | 1.2 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 0.3 | 4.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.3 | 1.3 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.3 | 4.1 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.2 | 0.5 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) |
| 0.2 | 0.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.2 | 0.8 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.2 | 0.6 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.2 | 0.5 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.1 | 0.4 | GO:0034657 | GID complex(GO:0034657) |
| 0.1 | 0.5 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.1 | 0.5 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.1 | 1.4 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 3.1 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 1.5 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.1 | 0.5 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.1 | 0.9 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 0.3 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.1 | 0.5 | GO:0030689 | Noc complex(GO:0030689) |
| 0.1 | 0.6 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 1.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 1.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 0.3 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.1 | 0.4 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 2.1 | GO:0043197 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
| 0.1 | 0.2 | GO:0000811 | GINS complex(GO:0000811) |
| 0.1 | 0.9 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 0.2 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.1 | 1.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 2.2 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.1 | 0.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 0.3 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.1 | 0.3 | GO:0031523 | Myb complex(GO:0031523) |
| 0.1 | 0.6 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.1 | 0.9 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 0.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.7 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 1.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 0.5 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 0.9 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 0.8 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.4 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 0.8 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 0.9 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 0.2 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.1 | 0.6 | GO:0030057 | desmosome(GO:0030057) |
| 0.1 | 3.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 1.0 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.2 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.0 | 0.2 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
| 0.0 | 0.9 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 0.9 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 2.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.5 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.0 | 0.8 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 0.8 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.9 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 1.2 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.3 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.5 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.5 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.4 | GO:1904949 | ATPase complex(GO:1904949) |
| 0.0 | 1.1 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 3.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 2.2 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
| 0.0 | 0.2 | GO:0098536 | deuterosome(GO:0098536) |
| 0.0 | 0.3 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.0 | 0.2 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.0 | 1.5 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 3.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 4.0 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 1.6 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 1.6 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.3 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.9 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 0.2 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.0 | 0.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.6 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 1.7 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.2 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 0.1 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 0.6 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 0.1 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.0 | 0.5 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 0.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.1 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 3.7 | GO:0005911 | cell-cell junction(GO:0005911) |
| 0.0 | 0.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.0 | 2.5 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.9 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 1.1 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 0.2 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.9 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 1.3 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 0.3 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.4 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 19.2 | GO:0038191 | neuropilin binding(GO:0038191) |
| 1.0 | 3.1 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.8 | 2.3 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.7 | 2.9 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
| 0.6 | 2.5 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.6 | 2.2 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.5 | 1.5 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.5 | 2.0 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.5 | 0.9 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.5 | 1.4 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
| 0.4 | 1.2 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.4 | 2.5 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
| 0.3 | 1.0 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.3 | 1.5 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.3 | 0.9 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.3 | 1.4 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
| 0.3 | 1.1 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.3 | 1.9 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.3 | 0.8 | GO:0019120 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
| 0.2 | 1.2 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.2 | 1.7 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.2 | 0.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 1.2 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.2 | 0.6 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.2 | 1.6 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.2 | 0.8 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.2 | 0.9 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.2 | 0.5 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.2 | 0.7 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 0.2 | 2.7 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.2 | 0.9 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.2 | 2.5 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.2 | 1.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.2 | 0.8 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
| 0.1 | 0.6 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 0.1 | 1.4 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 0.8 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.1 | 0.6 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 0.1 | 0.8 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.1 | 2.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.1 | 0.4 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.1 | 1.7 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.1 | 0.5 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.1 | 3.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.5 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.1 | 0.4 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.1 | 0.6 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.1 | 0.5 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.1 | 1.1 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 0.3 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153) |
| 0.1 | 0.8 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.1 | 0.6 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.1 | 1.1 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.1 | 0.4 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.1 | 0.7 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.1 | 0.3 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 4.1 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 1.9 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 0.3 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.1 | 0.4 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
| 0.1 | 0.3 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.1 | 0.5 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.1 | 0.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 1.1 | GO:0035004 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004) |
| 0.1 | 1.7 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.1 | 0.2 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.1 | 0.3 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 0.1 | 1.3 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 0.7 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.1 | 0.9 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 1.4 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.1 | 0.2 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.1 | 0.6 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 0.2 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.1 | 0.7 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 11.0 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.8 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.1 | 0.5 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 0.9 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 0.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 0.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 1.4 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
| 0.0 | 2.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.4 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.0 | 0.3 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.0 | 0.7 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.3 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 1.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.7 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.0 | 0.1 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 0.0 | 0.2 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.0 | 0.3 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.0 | 0.1 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.0 | 0.3 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.7 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 1.0 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.6 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.0 | 0.6 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.0 | 2.9 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 1.7 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 1.0 | GO:0043236 | laminin binding(GO:0043236) |
| 0.0 | 0.6 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.1 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
| 0.0 | 6.1 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.3 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.0 | 2.1 | GO:0061733 | peptide-lysine-N-acetyltransferase activity(GO:0061733) |
| 0.0 | 0.8 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.0 | 0.4 | GO:0016229 | steroid dehydrogenase activity(GO:0016229) |
| 0.0 | 0.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.2 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 3.2 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 1.4 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.2 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.0 | 0.5 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 0.7 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.5 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.2 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.0 | 0.6 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.6 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.2 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.0 | 0.4 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.0 | 0.0 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.0 | 0.1 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.0 | 0.9 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 1.5 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.8 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 1.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.0 | 0.3 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.4 | GO:0016835 | carbon-oxygen lyase activity(GO:0016835) |
| 0.0 | 1.4 | GO:0017124 | SH3 domain binding(GO:0017124) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.5 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.2 | 18.9 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 1.9 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
| 0.1 | 0.9 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 4.3 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 0.8 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
| 0.1 | 1.4 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.1 | 1.7 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 1.2 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 0.7 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
| 0.1 | 2.7 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
| 0.0 | 1.3 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.9 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.0 | 1.6 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.9 | PID_GMCSF_PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 0.8 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.0 | 1.0 | PID_ATM_PATHWAY | ATM pathway |
| 0.0 | 1.2 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.0 | PID_HIV_NEF_PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 1.0 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.9 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.5 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 0.6 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.1 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.0 | 1.0 | PID_CDC42_PATHWAY | CDC42 signaling events |
| 0.0 | 0.9 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.0 | 0.6 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
| 0.0 | 0.5 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 2.0 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.6 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.9 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 3.4 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.2 | 0.6 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.1 | 0.8 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 2.9 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.1 | 0.9 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 0.9 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 0.8 | REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.1 | 0.7 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 0.8 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 3.0 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.1 | 0.5 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 2.2 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.2 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.1 | 0.8 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 0.6 | REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.1 | 2.3 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 1.4 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 0.9 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 0.6 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 1.1 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 0.6 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.3 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 0.9 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.5 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.0 | 1.5 | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 0.9 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.8 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 1.4 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.9 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 0.9 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.0 | 0.8 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.6 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.3 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.4 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.3 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.5 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.3 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 0.2 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 1.4 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.5 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.4 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.3 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.5 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.2 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
| 0.0 | 0.3 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.2 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.6 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
